Published in J Immunol on February 01, 1975
Modulation of the immune response by a synthetic adjuvant and analogs. Proc Natl Acad Sci U S A (1976) 2.82
Endotoxin protein: a B-cell mitogen and polyclonal activator of C3H/HeJ lymphocytes. J Exp Med (1976) 2.77
Enterobacterial common antigen. Bacteriol Rev (1976) 2.41
Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. J Exp Med (1975) 2.22
Dissociation between mitogenicity and immunogenicity of TNP-lipopolysaccharide, a T-independent antigen. J Exp Med (1975) 2.10
Induction of murine autoimmune disease by chronic polyclonal B cell activation. J Exp Med (1983) 2.06
Induction of autoimmunity in good and poor responder mice with mouse thyroglobulin and lipopolysaccharide. J Exp Med (1977) 1.73
Cellular requirements for lipopolysaccharide adjuvanticity. A role for both T lymphocytes and macrophages for in vitro responses to particulate antigens. J Exp Med (1979) 1.73
Failure of endotoxin to increase nonspecific resistance to infection of lipopolysaccharide low-responder mice. Infect Immun (1976) 1.71
Mitogenic stimulation of murine spleen cells: relation to susceptibility to Salmonella infection. Infect Immun (1977) 1.68
Molecular requirements for B-lymphocyte activation by Escherichia coli lipopolysaccharide. Proc Natl Acad Sci U S A (1983) 1.51
Subclass-restricted IgG polyclonal antibody production in mice injected with lipid A-rich lipopolysaccharides. J Exp Med (1981) 1.48
Pretranslational regulation of the synthesis of the third component of complement in human mononuclear phagocytes by the lipid A portion of lipopolysaccharide. J Clin Invest (1985) 1.45
Cytokine response of T-cell subsets from Brucella abortus-infected mice to soluble Brucella proteins. Infect Immun (1993) 1.44
Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol. J Exp Med (1977) 1.37
Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med (1976) 1.34
Genetic analysis of lymphocyte activation by lipopolysaccharide Endotoxin. Infect Immun (1976) 1.33
Immunocompetent cells in resistance to bacterial infections. Bacteriol Rev (1976) 1.31
Role for endotoxin in the leukocyte infiltration accompanying Escherichia coli inflammation. Infect Immun (1982) 1.29
Immunogenicity and efficacy of oral or intranasal Shigella flexneri 2a and Shigella sonnei proteosome-lipopolysaccharide vaccines in animal models. Infect Immun (1993) 1.29
Genetic control of endotoxic responses in mice. J Exp Med (1978) 1.24
Role of endotoxin contamination in ribiosomal vaccines prepared from Salmonella typhimurium. Infect Immun (1977) 1.21
Effects of BCG infection on the susceptibility of mouse macrophages to endotoxin. Infect Immun (1979) 1.21
Genetical control of B-cell responses. IV. Inheritance of the unresponsiveness to lipopolysaccharides. J Exp Med (1975) 1.19
Identification of protective cell surface proteins in ribosomal fractions from Salmonella typhimurium. Infect Immun (1979) 1.16
Defective prostaglandin synthesis by C3H/HeJ mouse macrophages stimulated with endotoxin preparations. Infect Immun (1979) 1.16
Immune and mitogenic responses by BALB/c, C3H/HeJ, and nude mice to Brucella abortus bacterin and lipopolysaccharide. Infect Immun (1979) 1.16
Immunologic responsiveness of the C3H/HeJ mouse: differential ability of butanol-extracted lipopolysaccharide (LPS) to evoke LPS-mediated effects. J Exp Med (1978) 1.13
B-cell activation by lipopolysaccharide. Distinct pathways for induction of mitosis and antibody production. J Exp Med (1977) 1.11
Immunological responses of mice to lipopolysaccharide: lack of secondary responsiveness by C3H/HeJ mice. Infect Immun (1977) 1.09
Strain-dependent cytotoxic effects of endotoxin for mouse peritoneal macrophages. Infect Immun (1978) 1.09
Effect of lipid A-associated protein and lipid A on the expression of lipopolysaccharide activity. I. Immunological activity. Immunology (1980) 1.03
Mild alkaline hydrolysis of lipopolysaccharide endotoxin enhances its mitogencity for murine B cells. Infect Immun (1977) 1.01
Distribution of endotoxin (lipopolysaccharide) in the tissues of lipopolysaccharide-responsive and -unresponsive mice. Infect Immun (1978) 1.01
Variables which affect suppression of the immune response induced by Pseudomonas aeruginosa exotoxin A. Infect Immun (1986) 1.00
Structural features of Salmonella typhimurium lipopolysaccharide required for activation of tissue factor in human mononuclear cells. J Clin Invest (1977) 0.97
Immunological defects in SJL mice. Immunology (1986) 0.97
Suppression of the immune response in C3H/HeJ mice by protein-free lipopolysaccharides. J Exp Med (1978) 0.94
Lipopolysaccharide prevents apoptosis and induces responsiveness to antigen receptor cross-linking in immature B cells. Immunology (1996) 0.93
Transfer of Salmonella resistance and delayed hypersensitivity with murine-derived transfer factor. Infect Immun (1982) 0.91
Mitogenicity of Corynebacterium parvum for mouse lymphocytes. Clin Exp Immunol (1975) 0.91
Differential effects of polyadenylic: polyuridylic acid and lipopolysaccharide on the generation of cytotoxic T lymphocytes. J Exp Med (1978) 0.90
Elicitation of endotoxemic effects in C3H/HeJ mice with glucocorticoid antagonizing factor and partial characterization of the factor. Infect Immun (1978) 0.87
Biological effects of Escherichia coli lipopolysaccharide (LPS) in vivo. II. Selection in the mouse thymus of PHA- and con A-responsive cells. Immunology (1976) 0.86
Dissociation of the anti-hapten and anti-carrier responses of mice injected with dinitrophenylated lipopolysaccharide. Infect Immun (1981) 0.86
Immunological activities of Capnocytophaga cellular components. Infect Immun (1982) 0.85
Modulation of the immune response to sheep erythrocytes by lipid-free glycerol teichoic acid. Infect Immun (1979) 0.85
Bacterial lipopolysaccharide induces long-lasting IgA deficiency concurrently with features of polyclonal B cell activation in normal and in lupus-prone mice. Clin Exp Immunol (1991) 0.82
Response of C3H/HeJ and C3H/HeN mice and their peritoneal macrophages to the toxicity of Chlamydia psittaci elementary bodies. Infect Immun (1978) 0.82
Nocardia water-soluble mitogen and lipopolysaccharide. Comparative study of two adjuvants and B-cell mitogens in mice. Immunology (1977) 0.82
Mice refractory to lipopolysaccharide manifest high immunoglobulin A responses to orally administered antigen. Infect Immun (1980) 0.81
Breast milk lymphocyte response to K1 antigen of Escherichia coli. Infect Immun (1980) 0.81
Adjuvant activity of naturally occurring monophosphoryl lipopolysaccharide preparations from mucosa-associated bacteria. Infect Immun (2013) 0.79
Immunomodulation of the antibody response to lipopolysaccharide in C3H/HeJ mice by complexing with heterologous ribosomes. Infect Immun (1985) 0.79
The effect of endotoxin and endotoxin tolerance on inflammation induced by mycobacterial adjuvant. Yale J Biol Med (1984) 0.79
Relationship between biological activities of polymers. I. Immunogenicity, C3 activation, mitogenicity for B cells and adjuvant properties. Immunology (1975) 0.78
Susceptibility of lipopolysaccharide-responsive and -hyporesponsive ItyS Mice to infection with rough mutants of Salmonella typhimurium. Infect Immun (1996) 0.78
Modulating LPS signal transduction at the LPS receptor complex with synthetic Lipid A analogues. Adv Carbohydr Chem Biochem (2014) 0.77
Influence of lipopolysaccharide on graft versus host reactivity of lipopolysaccharide-unresponsive C3H/HeJ mice. Infect Immun (1979) 0.76
Effects of structural variations in synthetic glycolipids upon mitogenicity for spleen lymphocytes, adjuvancy for humoral immune response and on anti-tumour potential. Br J Cancer (1982) 0.76
Immunoglobulin M and immunoglobulin G responses in BALB/c mice to conjugated outer membrane extracts of four Salmonella serotypes. Infect Immun (1985) 0.75
Stimulation of murine lymphocyte blastogenesis by mitogens in heat-killed Histoplasma capsulatum yeast cells. Infect Immun (1987) 0.75
Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders. Biomol Ther (Seoul) (2016) 0.75
Genetic control of lymphocyte activation: lack of response to low doses of concanavalin A in lipopolysaccharide-nonresponder mice. J Exp Med (1977) 0.75
In vitro studies on the adjuvanticity of Brucella fractions. Infect Immun (1982) 0.75
Biological activity of Bordetella pertussis in lipopolysaccharide-resistant mice. Infect Immun (1981) 0.75
New phenotypic marker for lipopolysaccharide responsiveness. Infect Immun (1980) 0.75
Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence. J Exp Med (1984) 10.66
Endotoxins and disease mechanisms. Annu Rev Med (1987) 6.07
The effects of bacterial endotoxins on host mediation systems. A review. Am J Pathol (1978) 6.03
Binding of polymyxin B to the lipid A portion of bacterial lipopolysaccharides. Immunochemistry (1976) 5.43
Fractions of lipopolysaccharide from Escherichia coli O111:B4 prepared by two extraction procedures. J Biol Chem (1975) 4.80
Lymphocyte specificity to protein antigens. I. Characterization of the antigen-induced in vitro T cell-dependent proliferative response with lymph node cells from primed mice. J Immunol (1977) 4.67
Bacterial endotoxins and host immune responses. Adv Immunol (1979) 4.50
Activation of the classical and properdin pathways of complement by bacterial lipopolysaccharides (LPS). J Immunol (1977) 4.35
Kinetic differences in unresponsiveness of thymus and bone marrow cells. Science (1971) 4.13
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med (1983) 3.52
Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils. J Clin Invest (1975) 3.39
Cellular sites of immunologic unresponsiveness. Proc Natl Acad Sci U S A (1970) 3.01
Isolation of a lipid A bound polypeptide responsible for "LPS-initiated" mitogenesis of C3H/HeJ spleen cells. J Exp Med (1976) 2.88
Mothers as behavior therapists for their own children. Behav Res Ther (1965) 2.86
Immunological unresponsiveness. Adv Immunol (1973) 2.75
Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. Proc Natl Acad Sci U S A (1973) 2.61
Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol (1993) 2.56
Recent observations and concepts in immunological unresponsiveness and autoimmunity. Clin Exp Immunol (1971) 2.45
Bactericidal activity of the alternative complement pathway generated from 11 isolated plasma proteins. J Exp Med (1979) 2.39
Stimulation of a T-independent primary anti-hapten response in vitro by TNP-lipopolysaccharide (TNP-LPS). J Immunol (1975) 2.30
Analysis of autoimmunity through experimental models of thyroiditis and allergic encephalomyelitis. Adv Immunol (1980) 2.27
Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. J Exp Med (1975) 2.22
Enterically induced immunologic tolerance. I. Induction of suppressor T lymphoyctes by intragastric administration of soluble proteins. J Immunol (1978) 2.17
An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide. J Biol Chem (1997) 2.17
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
Transfer of experimental autoimmune thyroiditis by serum from thyroidectomized donors. J Exp Med (1969) 2.12
Dissociation between mitogenicity and immunogenicity of TNP-lipopolysaccharide, a T-independent antigen. J Exp Med (1975) 2.10
Dissociation of antigenicity and immunogenicity of neonatal epidermal allografts in the mouse. Transplantation (1990) 2.05
The production of thyroiditis and antibody following injection of unaltered thyroglobulin without adjuvant into rabbits previously stimulated with altered thyroglobulin. J Exp Med (1965) 1.96
Mediation systems in bacterial lipopolysaccharide-induced hypotension and disseminated intravascular coagulation. I. The role of complement. J Exp Med (1975) 1.91
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J Immunol (1993) 1.88
Propagation of antigen-specific T cell helper function in vitro. J Immunol (1979) 1.88
Specific endotoxic lipopolysaccharide-binding receptors on murine splenocytes. III. Binding specificity and characterization. J Immunol (1991) 1.86
The production of antisera to human gammaGlobulin subclasses in rabbits using immunological unresponsiveness. J Immunol (1968) 1.82
Studies on the induction of immunologic unresponsiveness. 3. Antigen form and mouse strain variation. J Immunol (1969) 1.81
Lipopolysaccharide nomenclature--past, present, and future. J Bacteriol (1986) 1.80
Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J Immunol (1990) 1.79
Direct evidence for Hageman factor (factor XII) activation by bacterial lipopolysaccharides (endotoxins). J Exp Med (1974) 1.74
Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. I. Detection of lipopolysaccharide-binding sites on splenocytes and splenocyte subpopulations. J Immunol (1988) 1.73
Lymphocyte specificity to protein antigens. II. Fine specificity of T-cell activation with cytochrome c and derived peptides as antigenic probes. J Exp Med (1979) 1.73
Cellular events during induction of immunologic unresponsiveness in adult mice. J Immunol (1971) 1.72
Studies on the induction of immunologic unresponsiveness. II. Kinetics. J Immunol (1967) 1.70
Cellular events in the induction of experimental allergic encephalomyelitis in rats. J Exp Med (1976) 1.69
Activation of the alternative complement pathway: recognition of surface structures on activators by bound C3b. J Immunol (1980) 1.65
Ability of antigen-specific helper cells to effect a class-restricted increase in total Ig-secreting cells in spleens after immunization with the antigen. J Exp Med (1979) 1.65
Synthesis and biochemical characterization of a photoactivatable, iodinatable, cleavable bacterial lipopolysaccharide derivative. J Biol Chem (1985) 1.64
The cellular and subcellular bases of immunosenescence. Adv Immunol (1989) 1.59
Inhibition of the mitogenic response to lipopolysaccharide (LPS) in mouse spleen cells by polymyxin B. J Immunol (1977) 1.57
Lipopolysaccharide-induced selective priming effects on tumor necrosis factor alpha and nitric oxide production in mouse peritoneal macrophages. J Exp Med (1993) 1.57
Binding and activation of the first component of human complement by the lipid A region of lipopolysaccharides. J Immunol (1978) 1.53
Inhibition of lipopolysaccharide-initiated activation of serum complement by polymyxin B. Infect Immun (1976) 1.53
The pulmonary vascular sequestration of neutrophils in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit. Am Rev Respir Dis (1987) 1.52
B-lymphocytes activation by the Fc region of IgG. J Exp Med (1977) 1.51
Cyclical production of antibody as a regulatory mechanism in the immune response. Adv Immunol (1975) 1.50
Lipid A-dependent lymphocyte proliferation in "endotoxin-nonresponder" mice. Rev Infect Dis (1984) 1.49
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49
Interstitial immune complex thyroiditis in mice: the role of autoantibody to thyroglobulin. J Exp Med (1974) 1.49
Orally induced tolerance. Definition at the cellular level. Int Arch Allergy Appl Immunol (1981) 1.48
Lymphokines and aging: interleukin-2 production and activity in aged animals. J Immunol (1981) 1.48
Studies on the induction of immunologic unresponsiveness. I. Effects of endotoxin and phytochemagglutinin. J Immunol (1967) 1.47
Effect of immunological unresponsiveness on different cell populations. Transplant Rev (1972) 1.45
Specific endotoxic lipopolysaccharide-binding proteins on murine splenocytes. II. Membrane localization and binding characteristics. J Immunol (1988) 1.43
Regulation of immune response by components of the complement cascade and their activated fragments. Springer Semin Immunopathol (1983) 1.41
Cutting edge: bacterial DNA and LPS act in synergy in inducing nitric oxide production in RAW 264.7 macrophages. J Immunol (1999) 1.39
Roles of T and B lymphocytes in the termination of unresponsiveness to autologous thyroglobulin in mice. J Exp Med (1974) 1.38
Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol. J Exp Med (1977) 1.37
Effect of chronic viral infection on the immune system. I. Comparison of the immune responsiveness of mice chronically infected with LCM virus with that of noninfected mice. J Immunol (1973) 1.36
Antibody response in rainbow trout (Salmo gairdneri) II. Studies on the kinetics of development of antibody-producing cells and on complement and natural hemolysin. J Immunol (1969) 1.36
The development of autoimmune thyroiditis in rabbits following injection of aqueous preparations of heterologous thyroglobulins. J Immunol (1967) 1.35
Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptors. J Exp Med (1982) 1.35
Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med (1976) 1.34
Bacterial endotoxins and pathogenesis. Rev Infect Dis (1983) 1.33
Cell-mediated immunity in aged mice: an underlying lesion in IL 2 synthesis. J Immunol (1982) 1.33
CD4+ T cell activation and tolerance induction in B cell knockout mice. J Exp Med (1996) 1.32
Th1 and Th2 clones differ in their response to a tolerogenic signal. J Immunol (1990) 1.31
Specific suppression of the immune response by HGG tolerant spleen cells. I. Parameters affecting the level of suppression. J Immunol (1976) 1.30
Adenosine and a related carbocyclic nucleoside analogue selectively inhibit tumor necrosis factor-alpha production and protect mice against endotoxin challenge. J Immunol (1993) 1.30
Reprogramming of lipopolysaccharide-primed macrophages is controlled by a counterbalanced production of IL-10 and IL-12. J Immunol (1998) 1.30
Major histocompatibility complex-restricted cellular interactions determining B cell activation. Eur J Immunol (1982) 1.30
Studies on membrane synthesis in Bacillus megaterium KM. J Mol Biol (1970) 1.30