Published in Biochemistry on February 01, 1969
Some studies on insolubilized nicotinamide nucleotides. Biochem J (1972) 0.83
Controlling human fixed-interval performance. J Exp Anal Behav (1969) 7.81
ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins. Proc Natl Acad Sci U S A (1986) 5.55
Deoxynucleoside [1-thio]triphosphates prevent proofreading during in vitro DNA synthesis. Proc Natl Acad Sci U S A (1981) 4.14
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development (2001) 3.14
Spinach leaf phosphoenolpyruvate carboxylase: purification, properties, and kinetic studies. Arch Biochem Biophys (1974) 2.46
Structure of mitochondrial aldehyde dehydrogenase: the genetic component of ethanol aversion. Structure (1997) 2.38
Conditioning history and maladaptive human operant behavior. Psychol Rep (1965) 2.38
Zinc in DNA polymerases. Biochem Biophys Res Commun (1971) 2.15
Preference and switching under ratio contingencies with humans. Psychol Rep (1966) 1.91
Aspects of enzyme mechanisms studies by nuclear spin relazation induced by paramagnetic probes. Adv Enzymol Relat Areas Mol Biol (1970) 1.90
On the fidelity of DNA replication: manganese mutagenesis in vitro. Biochemistry (1985) 1.90
Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase. Biochemistry (1989) 1.85
Horse liver aldehyde dehydrogenase. II. Kinetics and mechanistic implications of the dehydrogenase and esterase activity. J Biol Chem (1972) 1.83
Kinetic and magnetic resonance studies of the pyruvate kinase reaction. II. Complexes of enzyme, metal, and substrates. J Biol Chem (1966) 1.79
Involvement of glutamate 268 in the active site of human liver mitochondrial (class 2) aldehyde dehydrogenase as probed by site-directed mutagenesis. Biochemistry (1995) 1.68
Protective autoimmunity is a physiological response to CNS trauma. J Neurosci (2001) 1.64
Investigation of the active site cysteine residue of rat liver mitochondrial aldehyde dehydrogenase by site-directed mutagenesis. Biochemistry (1995) 1.56
Alzheimer's disease comorbidity in normal pressure hydrocephalus: prevalence and shunt response. J Neurol Neurosurg Psychiatry (2000) 1.56
Interaction of a spin-labeled analog of nicotinamide-adenine dinucleotide with alcohol dehydrogenase. I. Synthesis, kinetics, and electron paramagnetic resonance studies. Biochemistry (1969) 1.55
Environments and mechanistic roles of the tyrosine residues of delta 5-3-ketosteroid isomerase. Biochemistry (1993) 1.53
Mitochondrial aldehyde dehydrogenase activity is required for male fertility in maize. Plant Cell (2001) 1.50
Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase. J Biol Chem (1994) 1.50
Kinetic and magnetic resonance studies of active-site mutants of staphylococcal nuclease: factors contributing to catalysis. Biochemistry (1987) 1.46
NMR docking of a substrate into the X-ray structure of staphylococcal nuclease. Proteins (1992) 1.46
Horse liver aldehyde dehydrogenase. I. Purification and characterization. J Biol Chem (1972) 1.46
Vaccinia DNA topoisomerase I: single-turnover and steady-state kinetic analysis of the DNA strand cleavage and ligation reactions. Biochemistry (1994) 1.46
Instructional control of human operant responding during extinction following fixed-ratio conditioning. J Exp Anal Behav (1970) 1.45
Life events, depressive symptoms, and immune function. Am J Psychiatry (1987) 1.42
Conditioning history and the control of human avoidance and escape responding. J Exp Anal Behav (1969) 1.40
Cortical abnormalities in epilepsy revealed by local EEG synchrony. Neuroimage (2007) 1.37
Vaccinia DNA topoisomerase I: evidence supporting a free rotation mechanism for DNA supercoil relaxation. Biochemistry (1997) 1.35
NMR evidence for the participation of a low-barrier hydrogen bond in the mechanism of delta 5-3-ketosteroid isomerase. Proc Natl Acad Sci U S A (1996) 1.33
The role of metal ions in the mechanisms of DNA and RNA polymerases. CRC Crit Rev Biochem (1979) 1.33
Stuies on the interaction of substrate and monovalent and divalent cations with pyruvate kinase. Biochemistry (1966) 1.33
Mechanism of malic enzyme from pigeon liver. Magnetic resonance and kinetic studies of the role of Mn2+. J Biol Chem (1976) 1.32
Social confrontation "stress" in aggressive fish is associated with an endogenous opioid-mediated suppression of proliferative response to mitogens and nonspecific cytotoxicity. Brain Behav Immun (1989) 1.32
Real and imagined cost effects upon human fixed-interval responding. Psychol Rep (1965) 1.31
Magnesium stimulation of catalytic activity of horse liver aldehyde dehydrogenase. Changes in molecular weight and catalytic sites. J Biol Chem (1980) 1.30
Anorexia nervosa. Immaturity of the 24-hour luteinizing hormone secretory pattern. N Engl J Med (1974) 1.28
Proton magnetic relaxation studies of the interaction of D-xylose and xylitol with D-xylose isomerase. Characterization of metal-enzyme-substrate interactions. J Biol Chem (1975) 1.27
Kinetic analysis of Escherichia coli deoxyribonucleic acid polymerase I. J Biol Chem (1975) 1.27
The mechanism of aconitase action. I. Preparation, physical properties of the enzyme, and activation by iron (II). J Biol Chem (1971) 1.25
Rate-limiting steps for the esterase and dehydrogenase reaction catalyzed by horse liver aldehyde dehydrogenase. J Biol Chem (1976) 1.24
4-Oxalocrotonate tautomerase: pH dependence of catalysis and pKa values of active site residues. Biochemistry (1996) 1.24
Escherichia coli deoxyribonucleic acid polymerase I, a zinc metalloenzyme. Nuclear quadrupolar relaxation studies of the role of bound zinc. J Biol Chem (1973) 1.24
Kinetic and magnetic resonance studies of effects of genetic substitution of a Ca2+-liganding amino acid in staphylococcal nuclease. Biochemistry (1986) 1.24
Conformation of deoxynucleoside triphosphate substrates on DNA polymerase I from Escherichia coli as determined by nuclear magnetic relaxation. J Biol Chem (1975) 1.23
The role of Glu 57 in the mechanism of the Escherichia coli MutT enzyme by mutagenesis and heteronuclear NMR. Biochemistry (1996) 1.21
Catalytic role of the amino-terminal proline in 4-oxalocrotonate tautomerase: affinity labeling and heteronuclear NMR studies. Biochemistry (1996) 1.20
Immune system changes after the death of a partner in HIV-positive gay men. Psychosom Med (1996) 1.20
Molecular cloning, characterization, and potential roles of cytosolic and mitochondrial aldehyde dehydrogenases in ethanol metabolism in Saccharomyces cerevisiae. J Bacteriol (1998) 1.18
Cloning and expression of the full-length cDNAS encoding human liver class 1 and class 2 aldehyde dehydrogenase. Alcohol Clin Exp Res (1993) 1.18
The mechanism of Escherichia coli deoxyribonucleic acid polymerase I. Magnetic resonance and kinetic studies of the role of metals. J Biol Chem (1972) 1.17
Solution structure of the MutT enzyme, a nucleoside triphosphate pyrophosphohydrolase. Biochemistry (1995) 1.17
Increase in the stoichiometry of the functioning active sites of horse liver aldehyde dehydrogenase in the presence of magnesium ions. Arch Biochem Biophys (1980) 1.15
Structures of enzyme-bound metal-nucleotide complexes in the phosphoryl transfer reaction of muscle pyruvate kinase. 31P NMR studies with magnesium and kinetic studies with chromium nucleotides. J Biol Chem (1977) 1.15
Aldehyde dehydrogenase activity as the rate-limiting factor for acetaldehyde metabolism in rat liver. Arch Biochem Biophys (1985) 1.14
Escherichia coli orf17 codes for a nucleoside triphosphate pyrophosphohydrolase member of the MutT family of proteins. Cloning, purification, and characterization of the enzyme. J Biol Chem (1996) 1.13
Kinetic and magnetic resonance studies of the mechanism of D-xylose isomerase. I. Binary and ternary complexes with manganese(II), substrates, and inhibitors. J Biol Chem (1972) 1.12
The formation of anhydrochymotrypsin by removing the elements of water from the serine at the active site. J Am Chem Soc (1966) 1.12
Electron paramagnetic resonance, 1-H, and 13C nuclear magnetic resonance studies of the interaction of manganese and bicarbonate with ribulose 1, 5-diphosphate carboxylase. J Biol Chem (1974) 1.12
Release of neutrophil chemotactic activity during immediate hypersensitivity reactions in humans. Ann Intern Med (1977) 1.12
Human liver mitochondrial aldehyde dehydrogenase: three-dimensional structure and the restoration of solubility and activity of chimeric forms. Protein Sci (1999) 1.12
Basis for half-of-the-site reactivity and the dominance of the K487 oriental subunit over the E487 subunit in heterotetrameric human liver mitochondrial aldehyde dehydrogenase. Biochemistry (2000) 1.11
Anorexia nervosa and gonadal dysgenesis. Further evidence of a relationship. Arch Gen Psychiatry (1977) 1.11
Combined effects of two mutations of catalytic residues on the ketosteroid isomerase reaction. Biochemistry (1990) 1.09
15N NMR relaxation studies of free and inhibitor-bound 4-oxalocrotonate tautomerase: backbone dynamics and entropy changes of an enzyme upon inhibitor binding. Biochemistry (1996) 1.09
Primary structures of rat and bovine liver mitochondrial aldehyde dehydrogenases deduced from cDNA sequences. Eur J Biochem (1989) 1.09
Hydrogen bonding at the active site of delta 5-3-ketosteroid isomerase. Biochemistry (1997) 1.08
Catalytic mechanism of an active-site mutant (D38N) of delta 5-3-ketosteroid isomerase. Direct spectroscopic evidence for dienol intermediates. Biochemistry (1991) 1.08
Studies of the mechanism of the delta 5-3-ketosteroid isomerase reaction by substrate, solvent, and combined kinetic deuterium isotope effects on wild-type and mutant enzymes. Biochemistry (1990) 1.08
Nuclear relaxation measurements of the geometry of enzyme-bound substrates and analogs. Methods Enzymol (1978) 1.07
NMR studies of conformations and interactions of substrates and ribonucleotide templates bound to the large fragment of DNA polymerase I. Biochemistry (1986) 1.07
Vaccinia DNA topoisomerase I: kinetic evidence for general acid-base catalysis and a conformational step. Biochemistry (1994) 1.06
Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate. Biochemistry (1998) 1.06
The aldehyde dehydrogenase ALDH2*2 allele exhibits dominance over ALDH2*1 in transduced HeLa cells. J Clin Invest (1995) 1.06
High-precision measurement of hydrogen bond lengths in proteins by nuclear magnetic resonance methods. Proteins (1999) 1.05
Nuclear magnetic resonance studies of the function of potassium in the mechanism of pyruvate kinase. Biochemistry (1972) 1.05
Most patients with multiple sclerosis or a clinically isolated demyelinating syndrome should be treated at the time of diagnosis. Arch Neurol (2006) 1.05
NMR studies of the role of hydrogen bonding in the mechanism of triosephosphate isomerase. Biochemistry (1997) 1.05
Involvement of glutamate 399 and lysine 192 in the mechanism of human liver mitochondrial aldehyde dehydrogenase. J Biol Chem (1997) 1.05
NMR studies of the MgATP binding site of adenylate kinase and of a 45-residue peptide fragment of the enzyme. Biochemistry (1985) 1.04
Evidence for two distinct active sites on aldehyde dehydrogenase. J Biol Chem (1988) 1.04
Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenases. Protein Sci (1999) 1.04
Impaired natural killer cell activity during bereavement. Brain Behav Immun (1987) 1.03
Grief and depression after miscarriage: their separation, antecedents, and course. Psychosom Med (1996) 1.03
Import of chemically synthesized signal peptides into rat liver mitochondria. J Biol Chem (1990) 1.03
The mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashion. J Clin Invest (1996) 1.03
Mutational, kinetic, and NMR studies of the roles of conserved glutamate residues and of lysine-39 in the mechanism of the MutT pyrophosphohydrolase. Biochemistry (2000) 1.03
The potential roles of the conserved amino acids in human liver mitochondrial aldehyde dehydrogenase. J Biol Chem (1997) 1.03
Proton transfer in the mechanism of triosephosphate isomerase. Biochemistry (1998) 1.02
Molecular cloning of the mitochondrial aldehyde dehydrogenase gene of Saccharomyces cerevisiae by genetic complementation. J Bacteriol (1991) 1.02
Magnetic resonance and kinetic studies of the manganese(II) ion and substrate complexes of the catalytic subunit of adenosine 3',5'-monophosphate dependent protein kinase from bovine heart. Biochemistry (1979) 1.02
Immune and neuroendocrine changes during bereavement. Psychiatr Clin North Am (1987) 1.02
Studies of the catalytic mechanism of an active-site mutant (Y14F) of delta 5-3-ketosteroid isomerase by kinetic deuterium isotope effects. Biochemistry (1991) 1.02
Purification of liver aldehyde dehydrogenase by p-hydroxyacetophenone-sepharose affinity matrix and the coelution of chloramphenicol acetyl transferase from the same matrix with recombinantly expressed aldehyde dehydrogenase. Protein Expr Purif (1992) 1.02
Positioning of a spin-labeled substrate analogue into the structure of delta 5-3-ketosteroid isomerase by combined kinetic, magnetic resonance, and X-ray diffraction methods. Biochemistry (1987) 1.02
The enzymatic carboxylation of phosphoenolpyruvate. IV. The binding of manganese and substrates by phosphoenolpyruvate carbosy-kinase and phosphoenolypyruvate carboxylase. J Biol Chem (1968) 1.02
Hyperactivity in anorexia nervosa: a fundamental clinical feature. Compr Psychiatry (1978) 1.02
Dual divalent cation requirement of the MutT dGTPase. Kinetic and magnetic resonance studies of the metal and substrate complexes. J Biol Chem (1994) 1.01