Published in Proc Natl Acad Sci U S A on September 01, 1982
The paradoxical functions of B cells and antibodies in transplantation. J Immunol (2013) 0.92
Diversity at the variable-joining region boundary of lambda light chains has a pronounced effect on immunoglobulin ligand-binding activity. Proc Natl Acad Sci U S A (1984) 0.91
T helper cells recognize an idiotope located on peptide 88-114/117 of the light chain variable domain of an isologous myeloma protein (315). J Exp Med (1983) 0.83
Monoclonal anti-VH141 antibodies that specifically recognize the heavy chain variable region of, and are closely related to, MOPC141 myeloma protein whose VH gene belongs to VHQ52 family. Immunology (1991) 0.75
Activation of idiotype-specific CD4+ T-cell line: cellular processing of exogenous self-immunoglobulin. Immunology (1990) 0.75
Towards a network theory of the immune system. Ann Immunol (Paris) (1974) 16.43
Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. Proc Natl Acad Sci U S A (1978) 6.80
Affinity labeling of a phosphorylcholine binding mouse myeloma protein. Biochemistry (1972) 4.26
Expression and function of idiotypes of lymphocytes. Adv Immunol (1978) 4.16
The three-dimensional structure of a phosphorylcholine-binding mouse immunoglobulin Fab and the nature of the antigen binding site. Proc Natl Acad Sci U S A (1974) 3.92
The role of antigen-specific T cell factors in the immune response. Adv Immunol (1979) 2.95
Affinity labeling of a mouse myeloma protein which binds nitrophenyl ligands. Kinetics of labeling and isolation of a labeled peptide. Biochemistry (1970) 2.88
Similar idiotypic specificities in immunoglobulin fractions with different antibody functions or even without detectable antibody function. Proc Natl Acad Sci U S A (1971) 2.73
Recognition of idiotypes in lymphocyte interactions. II. Antigen-independent cooperation between T and B lymphocytes that possess similar and complementary idiotypes. Eur J Immunol (1978) 2.47
Amino acid sequence of the light chain of a mouse myeloma protein (MOPC-315). Biochemistry (1973) 2.30
Presence on idiotype-specific suppressor T cells of receptors that interact with molecules bearing the idiotype. J Exp Med (1977) 2.29
Autoimmune-like antibodies to the ligand-binding sites of myeloma proteins. Proc Natl Acad Sci U S A (1971) 2.17
The induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells. J Exp Med (1979) 2.09
Myeloma proteins as tumor-specific transplantation antigens. Proc Natl Acad Sci U S A (1972) 2.09
The three dimensional structure of a combining region-ligand complex of immunoglobulin NEW at 3.5-A resolution. Proc Natl Acad Sci U S A (1974) 1.97
Recovery of binding activity in reconstituted mouse myeloma proteins. Biochemistry (1971) 1.75
An active antibody fragment (Fv) composed of the variable portions of heavy and light chains. Biochemistry (1973) 1.68
Antibodies to idiotypes of isologous immunoglobulins. J Exp Med (1975) 1.56
Suppression of idiotype and generation of suppressor T cells with idiotype-conjugated thymocytes. J Exp Med (1979) 1.56
Antigen- and receptor-driven regulatory mechanisms. II. Induction of suppressor T cells with idiotype-coupled syngeneic spleen cells. J Exp Med (1979) 1.42
DNA sequences of the joining regions of mouse lambda light chain immunoglobulin genes. Proc Natl Acad Sci U S A (1982) 1.38
Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity. Proc Natl Acad Sci U S A (1974) 1.36
Idiotype-specific T cell immunity. I. Generation of effector and suppressor T lymphocytes reactive with myeloma idiotypic determinants. J Immunol (1980) 1.35
Recognition of immunoglobulin idiotypes by thymus-derived lymphocytes. Proc Natl Acad Sci U S A (1975) 1.33
Identification of a third type of lambda light chain in mouse immunoglobulins. Proc Natl Acad Sci U S A (1981) 1.31
Structural alterations in J regions of mouse immunoglobulin lambda genes are associated with differential gene expression. Nature (1982) 1.30
Crystallization with hapten of the Fab' fragment from a mouse IgA myeloma protein with antidinitrophenyl activity. J Biol Chem (1971) 1.24
Subunit interactions in mouse myeloma proteins with anti-galactan activity. Proc Natl Acad Sci U S A (1976) 1.13
Antigen recognition by T cells. I. Suppressor T cells fail to recognize cross-reactivity between native and denatured ovalbumin. J Immunol (1980) 1.09
The effect of light chain gene expression on the inheritance of an idiotype associated with primary anti-(4-hydroxy-3-nitrophenyl)acetyl(NP) antibodies. Eur J Immunol (1979) 1.00
Quantitation of conformational changes on chemical modification of proteins: use of succinylated proteins as a model. Arch Biochem Biophys (1967) 0.98
T helper lymphocytes recognize the VL domain of the isologous mouse myeloma protein 315. Scand J Immunol (1979) 0.91
Molecular heterogeneity and fine specificity of BALB/c antibodies elicited by isologous myeloma protein. Eur J Immunol (1978) 0.87
Immunization with the light chain and the VL domain of the isologous myeloma protein 315 inhibits growth of mouse plasmacytoma MOPC315. Scand J Immunol (1980) 0.84
Mouse myeloma proteins with lambda 2 and lambda 3 light chains. J Immunol (1981) 0.83
Immune responses of BALB/c mice to the idiotype of T15 and of other myeloma proteins of BALB/c origin: implications for an immune network and antibody multispecificity. Cold Spring Harb Symp Quant Biol (1977) 0.83
Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer (2001) 5.36
Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages. J Exp Med (1975) 5.19
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences. Nature (1984) 5.19
Mouse myeloma proteins with antihapten antibody acitivity. The protein produced by plasma cell tumor MOPC-315. Biochemistry (1968) 4.83
Recombination and clonal groupings within Helicobacter pylori from different geographical regions. Mol Microbiol (1999) 4.72
Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response. Immunity (1996) 4.68
Homeostasis-stimulated proliferation drives naive T cells to differentiate directly into memory T cells. J Exp Med (2000) 4.54
EXCITATION ENERGY TRANSFER AND THE QUANTITATIVE STUDY OF THE ANTIBODY HAPTEN REACTION. Proc Natl Acad Sci U S A (1960) 4.43
Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science (1997) 4.19
Helicobacter pylori CagA protein can be tyrosine phosphorylated in gastric epithelial cells. J Exp Med (2000) 3.74
Structure, organization, and somatic rearrangement of T cell gamma genes. Cell (1985) 3.49
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature (1984) 3.46
Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell (1995) 3.08
Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan. J Clin Microbiol (1997) 2.89
Naturally processed viral peptides recognized by cytotoxic T lymphocytes on cells chronically infected by human immunodeficiency virus type 1. J Exp Med (1994) 2.81
Distinctiveness of genotypes of Helicobacter pylori in Calcutta, India. J Bacteriol (2000) 2.81
Origins of MIT inquiry. Nature (1991) 2.81
Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells. Mol Cell Biol (1983) 2.70
NF-kappa B RelA-deficient lymphocytes: normal development of T cells and B cells, impaired production of IgA and IgG1 and reduced proliferative responses. J Exp Med (1997) 2.66
Hyperammonaemia and Helicobacter pylori. Lancet (1995) 2.59
Limited diversity of the rearranged T-cell gamma gene. Nature (1985) 2.58
Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera. Proc Natl Acad Sci U S A (1984) 2.54
A novel serine esterase expressed by cytotoxic T lymphocytes. Nature (1985) 2.43
Kinetic and affinity limits on antibodies produced during immune responses. Proc Natl Acad Sci U S A (1995) 2.41
Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes. Immunity (1994) 2.39
A naturally occurring peptide recognized by alloreactive CD8+ cytotoxic T lymphocytes in association with a class I MHC protein. Cell (1992) 2.34
Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells. Oncogene (2007) 2.34
The relative affinity of antibodies synthesized in the secondary response. J Exp Med (1967) 2.33
Attachment of an anti-receptor antibody to non-target cells renders them susceptible to lysis by a clone of cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1984) 2.32
Amino acid sequence of the light chain of a mouse myeloma protein (MOPC-315). Biochemistry (1973) 2.30
An optimal viral peptide recognized by CD8+ T cells binds very tightly to the restricting class I major histocompatibility complex protein on intact cells but not to the purified class I protein. Proc Natl Acad Sci U S A (1991) 2.26
Preparation and characterization of antibodies specific for the 2,4,6-trinitrophenyl group. Biochemistry (1966) 2.20
Autoimmune-like antibodies to the ligand-binding sites of myeloma proteins. Proc Natl Acad Sci U S A (1971) 2.17
A DEMONSTRATION OF ANTIBODY ACTIVITY ON MICROSOMES. Proc Natl Acad Sci U S A (1959) 2.12
Myeloma proteins as tumor-specific transplantation antigens. Proc Natl Acad Sci U S A (1972) 2.09
High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. Proc Natl Acad Sci U S A (1994) 2.09
Phosphotyrosine-containing proteins isolated by affinity chromatography with antibodies to a synthetic hapten. Nature (1981) 2.08
Functional differences between memory and naive CD8 T cells. Proc Natl Acad Sci U S A (1999) 1.94
Variations in the number of peptide-MHC class I complexes required to activate cytotoxic T cell responses. J Immunol (1995) 1.91
Anterior sagittal anorectoplasty for rectovestibular and anovestibular fistula. J Pediatr Surg (1992) 1.89
Vesicular stomatitis virus glycoprotein is necessary for H-2-restricted lysis of infected cells by cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1978) 1.88
Serine esterase in cytolytic T lymphocytes. Nature (1986) 1.85
Secondary, tertiary, and quaternary structure of T-cell-specific immunoglobulin-like polypeptide chains. Proc Natl Acad Sci U S A (1986) 1.81
Sequential changes in the relative affinity of antibodies synthesized during the immune response. J Exp Med (1967) 1.80
Semisynthetic -lactam antibiotics. 2. Synthesis and properties of D- and L- -sulfobenzylpenicillins. J Med Chem (1972) 1.70
Subunit structure and number of combining sites of the immunoglobulin A myeloma protein produced by mouse plasmacytoma MOPC-315. Biochemistry (1971) 1.68
Symposium on in vitro studies of the immune response. I. Variations in the immune response to a simple determinant. Bacteriol Rev (1966) 1.65
A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone. Proc Natl Acad Sci U S A (1993) 1.63
Cognate peptides induce self-destruction of CD8+ cytolytic T lymphocytes. Proc Natl Acad Sci U S A (1990) 1.63
Dependence of lymphopenia-induced T cell proliferation on the abundance of peptide/ MHC epitopes and strength of their interaction with T cell receptors. Proc Natl Acad Sci U S A (2001) 1.61
Antibodies to idiotypes of isologous immunoglobulins. J Exp Med (1975) 1.56
Amino acid sequence of the light chain from a mouse myeloma protein with anti-hapten activity: evidence for a third type of light chain. Proc Natl Acad Sci U S A (1971) 1.52
Experimental approaches to homogenous antibody populations. Myeloma proteins with antihapten antibody activity. Fed Proc (1970) 1.51
Myeloma proteins with anti-hapten antibody activity: epsilon-2,4-dinitrophenyl lysine binding by the protein produced by mouse plasmacytoma MOPC-460. J Immunol (1969) 1.51
Calcium ion concentrations and DNA fragmentation in target cell destruction by murine cloned cytotoxic T lymphocytes. J Exp Med (1988) 1.49
The immune response to a simple antigenic determinant. Harvey Lect (1966) 1.47
Peptide antagonism and T cell receptor interactions with peptide-MHC complexes. Immunity (1998) 1.46
Heat shock fusion proteins as vehicles for antigen delivery into the major histocompatibility complex class I presentation pathway. Proc Natl Acad Sci U S A (1997) 1.46
Neurosecretory cell: capable of conducting impulse in rats. Science (1966) 1.45
Specificity of the immune response to the 2,4-dinitrophenyl and 2,4,6-trinitrophenyl groups. Ligand binding and fluorescence properties of cross-reacting antibodies. J Exp Med (1969) 1.44
The law of mass action governs antigen-stimulated cytolytic activity of CD8+ cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1995) 1.43
Semisynthetic beta-lactam antibiotics. 6. 1 Sulfocephalosporins and their antipseudomonal activities. J Med Chem (1974) 1.42
Deleted HTLV provirus in peripheral blood cells of a patient with T-cell prolymphocytic leukaemia. Br J Haematol (1998) 1.41
Helicobacter pylori infection induces hyperammonaemia in Mongolian gerbils with liver cirrhosis. Gut (2001) 1.41
Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule. Proc Natl Acad Sci U S A (1990) 1.41
Human pregnancy serum suppresses the proliferative response of lymphocytes to autologous PHA-activated T lymphoblasts. Am J Reprod Immunol (1996) 1.40
The performance of a novel ball-tipped Flush knife for endoscopic submucosal dissection: a case-control study. Aliment Pharmacol Ther (2010) 1.39
Effects of N alpha-tosyl-L-lysyl-chloromethylketone on the activity of cytotoxic T lymphocytes. J Immunol (1980) 1.39
Active and passive mechanical characteristics of bovine mesenteric lymphatics. Am J Physiol (1980) 1.39
Neuroprotective effects of gelsolin during murine stroke. J Clin Invest (1999) 1.38
In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist. Eur J Pharmacol (2000) 1.36
Amino-acid sequence of the variable region of the heavy (alpha) chain of a mouse myeloma protein with anti-hapten activity. Proc Natl Acad Sci U S A (1974) 1.36
Junctional amino acids determine the maturation pathway of an antibody. Immunity (1999) 1.36
Recognition of immunoglobulin idiotypes by thymus-derived lymphocytes. Proc Natl Acad Sci U S A (1975) 1.33
Adenomatoid Transformation of the Glomerular Capsular Epithelium. Am J Pathol (1946) 1.33
Full-length sequence analysis of the vacA gene from cytotoxic and noncytotoxic Helicobacter pylori. J Infect Dis (1998) 1.32
Usefulness of selective arterial secretin injection test for localization of gastrinoma in the Zollinger-Ellison syndrome. Ann Surg (1987) 1.32
Specificity and structure of the myeloma protein produced by mouse plasmacytoma MOPC-460. Biochemistry (1971) 1.32
Synthetic phospholipid vesicles containing a purified viral antigen and cell membrane proteins stimulate the development of cytotoxic T lymphocytes. J Exp Med (1979) 1.31
Identification of a third type of lambda light chain in mouse immunoglobulins. Proc Natl Acad Sci U S A (1981) 1.31
Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor. Proc Natl Acad Sci U S A (2001) 1.30
Resistance of cytotoxic T lymphocytes to lysis by a clone of cytotoxic T lymphocytes. Proc Natl Acad Sci U S A (1987) 1.30
Expression of the T-cell-specific gamma gene is unnecessary in T cells recognizing class II MHC determinants. Nature (1985) 1.29
Retrospective study of technical aspects and complications of endoscopic submucosal dissection for laterally spreading tumors of the colorectum. Endoscopy (2010) 1.29
Degeneracy in the secondary immune response: stimulation of antibody formation by cross-reacting antigens. Isr J Med Sci (1969) 1.27
In vivo cytotoxic T lymphocyte elicitation by mycobacterial heat shock protein 70 fusion proteins maps to a discrete domain and is CD4(+) T cell independent. J Exp Med (2000) 1.26
Gelsolin binding and cellular presentation of lysophosphatidic acid. J Biol Chem (2000) 1.24
The natural abundance of lambda2-light chains in inbred mice. J Exp Med (1978) 1.23
Profile of Helicobacter pylori cytotoxin derived from two areas of Japan with different prevalence of atrophic gastritis. Gut (1996) 1.23
Crawling movements of lymphocytes on and beneath fibroblasts in culture. Proc Natl Acad Sci U S A (1979) 1.21
Cell-bound myeloma proteins on the surface of myeloma cells: potential targets for the immune system. Proc Natl Acad Sci U S A (1972) 1.20
Affinity labeling of the heavy and light chains of a myeloma protein with anti-2,4-dinitrophenyl activity. Proc Natl Acad Sci U S A (1970) 1.20
Cofilin and gelsolin segment-1: molecular dynamics simulation and biochemical analysis predict a similar actin binding mode. J Mol Biol (1998) 1.20
IMPAIRMENT OF ANTIBODY RESPONSE IN PYRIDOXINE-DEFICIENT RATS. J Exp Med (1947) 1.19
Cell motility as a prognostic factor in Stage I nonsmall cell lung carcinoma: the role of gelsolin expression. Cancer (1999) 1.18
Inhibition of cytotoxic T lymphocyte activity by concanavalin A. J Immunol (1982) 1.17
Localization of affinity-labeled residues on the heavy and light chain of two myeloma proteins with anti-hapten activity. Biochemistry (1972) 1.17