Published in J Virol on March 01, 1981
Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production. J Virol (1986) 2.27
Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus. Mol Cell Biol (1992) 1.83
Separation of PP2A core enzyme and holoenzyme with monoclonal antibodies against the regulatory A subunit: abundant expression of both forms in cells. Mol Cell Biol (1997) 1.79
Cellular proteins that associate with the middle and small T antigens of polyomavirus. J Virol (1988) 1.78
Molecular cloning and sequence of cDNA encoding polyoma medium tumor antigen-associated 61-kDa protein. Proc Natl Acad Sci U S A (1989) 1.69
Complete interaction of cellular 56,000- and 32,000-Mr proteins with simian virus 40 small-t antigen in productively infected cells. J Virol (1987) 1.63
Purification of biologically active simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A (1983) 1.61
Molecular model of the A subunit of protein phosphatase 2A: interaction with other subunits and tumor antigens. J Virol (1994) 1.56
BK virus and human cancer: innocent until proven guilty. Semin Cancer Biol (2009) 1.45
Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation. J Virol (1994) 1.42
Constant expression and activity of protein phosphatase 2A in synchronized cells. Mol Cell Biol (1991) 1.23
Homologous cellular proteins associated with simian virus 40 small T antigen and polyomavirus medium T antigen. J Virol (1988) 1.21
Isolation and characterization of NIH 3T3 cells expressing polyomavirus small T antigen. J Virol (1986) 1.18
Novel monoclonal antibodies that differentiate between the binding of pp60c-src or protein phosphatase 2A by polyomavirus middle T antigen. J Virol (1993) 1.12
Association of simian virus 40 small-t antigen with the 61-kilodalton component of a cellular protein complex. J Virol (1990) 1.11
Characterization of the interaction of polyomavirus middle T antigen with type 2A protein phosphatase. J Virol (1992) 1.11
Human cancer-associated mutations in the Aα subunit of protein phosphatase 2A increase lung cancer incidence in Aα knock-in and knockout mice. Mol Cell Biol (2011) 1.00
Protein phosphatases and DNA tumor viruses: transformation through the back door? Cell Regul (1991) 1.00
The cellular proteins which can associate specifically with polyomavirus middle T antigen in human 293 cells include the major human 70-kilodalton heat shock proteins. J Virol (1989) 0.99
Presence in growth-arrested cells of cellular proteins that interact with simian virus 40 small-t antigen. J Virol (1982) 0.89
The role of Merkel cell polyomavirus and other human polyomaviruses in emerging hallmarks of cancer. Viruses (2015) 0.85
Cellular proteins which can specifically associate with simian virus 40 small t antigen. J Virol (1986) 0.84
Functional role of BK virus tumor antigens in transformation. J Virol (1988) 0.80
Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells. Cell (1978) 5.23
New region of the simian virus 40 genome required for efficient viral transformation. Proc Natl Acad Sci U S A (1978) 4.24
The nucleotide sequence and genome organization of the polyoma early region: extensive nucleotide and amino acid homology with SV40. Cell (1979) 4.23
Characterization of T antigens in polyoma-infected and transformed cells. Cell (1978) 3.76
Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus. Proc Natl Acad Sci U S A (1977) 3.68
The roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells. Cell (1979) 3.57
Sequence from early region of polyoma virus DNA containing viral replication origin and encoding small, middle and (part of) large T antigens. Cell (1979) 3.29
Amino acid sequence homology between polyoma and SV40 tumour antigens deduced from nucleotide sequences. Nature (1978) 3.11
Host range selection of transformation-defective hr-t mutants of polyoma virus. Virology (1977) 2.68
Cellular proteins associated with simian virus 40 early gene products in newly infected cells. J Virol (1979) 2.44
Cellular alterations dependent upon the polyoma virus Hr-t function: separation of mitogenic from transforming capacities. Cell (1978) 2.05
Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus. Proc Natl Acad Sci U S A (1973) 2.01
Simian virus 40 small-t protein is required for loss of actin cable networks in rat cells. J Virol (1980) 1.68
Untransformed rat cells containing free and integrated DNA of a polyoma nontransforming (Hr-t) mutant. Cell (1979) 1.65
Relationship between the methionine tryptic peptides of simian virus 40 and BK virus tumor antigens. J Virol (1977) 1.38
Virion polypeptide composition of the human papovavirus BK: comparison with simian virus 40 and polyoma virus. J Virol (1975) 1.30
Multiple forms of polyoma virus tumor antigens from infected and transformed cells. J Virol (1979) 1.04
Identification of the human papovavirus T antigen and comparison with the simian virus 40 protein a. Virology (1977) 0.93
SV40 17K protein is associated with two cellular proteins. Cold Spring Harb Symp Quant Biol (1980) 0.89
Regulation of tumor antigen synthesis by simain virus 40 gene A. J Virol (1975) 9.93
Organization and expression of early genes of simian virus 40. Proc Natl Acad Sci U S A (1978) 7.10
Identification of simian virus 40 protein A. J Virol (1977) 4.93
Immune reconstitution inflammatory syndrome in natalizumab-associated PML. Neurology (2011) 4.63
Modification of simian virus 40 protein A. J Virol (1977) 3.79
Establishment of a line of human fetal glial cells that supports JC virus multiplication. Proc Natl Acad Sci U S A (1985) 2.93
Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proc Natl Acad Sci U S A (1998) 2.89
Control of protein phosphatase 2A by simian virus 40 small-t antigen. Mol Cell Biol (1991) 2.80
JC virus infection of hematopoietic progenitor cells, primary B lymphocytes, and tonsillar stromal cells: implications for viral latency. J Virol (1996) 2.60
Cellular proteins associated with simian virus 40 early gene products in newly infected cells. J Virol (1979) 2.44
Detection of JC virus DNA in human tonsil tissue: evidence for site of initial viral infection. J Virol (1998) 2.43
Large T antigens of many polyomaviruses are able to form complexes with the retinoblastoma protein. J Virol (1990) 2.40
The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain. Mol Cell Biol (1997) 2.33
Involvement of JC virus-infected mononuclear cells from the bone marrow and spleen in the pathogenesis of progressive multifocal leukoencephalopathy. N Engl J Med (1988) 2.32
JC virus DNA is present in the mucosa of the human colon and in colorectal cancers. Proc Natl Acad Sci U S A (1999) 2.08
Detection of JC virus DNA in peripheral lymphocytes from patients with and without progressive multifocal leukoencephalopathy. Ann Neurol (1992) 2.07
Malignant transformation of BHK21 clone 13 cells by BK virus--a human papovavirus. Proc Natl Acad Sci U S A (1973) 2.01
Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigen. Mol Cell Biol (1991) 1.99
Transient exposure to HIV-1 Tat protein results in cytokine production in macrophages and astrocytes. A hit and run phenomenon. J Biol Chem (1999) 1.90
Induction of cyclin D1 by simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A (1996) 1.86
HIV-1 infection of subcortical astrocytes in the pediatric central nervous system. Neurology (1994) 1.86
Management and outcome of CSF-JC virus PCR-negative PML in a natalizumab-treated patient with MS. Neurology (2011) 1.83
Progressive multifocal leukoencephalopathy. Semin Neurol (1999) 1.75
A classification scheme for human polyomavirus JCV variants based on the nucleotide sequence of the noncoding regulatory region. J Neurovirol (2001) 1.72
HIV-1 Tat induces monocyte chemoattractant protein-1-mediated monocyte transmigration across a model of the human blood-brain barrier and up-regulates CCR5 expression on human monocytes. J Immunol (1999) 1.63
Complete interaction of cellular 56,000- and 32,000-Mr proteins with simian virus 40 small-t antigen in productively infected cells. J Virol (1987) 1.63
Comparison of antibody titers determined by hemagglutination inhibition and enzyme immunoassay for JC virus and BK virus. J Clin Microbiol (2000) 1.63
Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro. J Virol (1992) 1.55
Progression of progressive multifocal leukoencephalopathy despite treatment with beta-interferon. Neurology (2006) 1.47
Critical role for SV40 small-t antigen in human cell transformation. Virology (2001) 1.46
Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody. Exp Neurol (2000) 1.45
Interaction of the human polyomavirus, JCV, with human B-lymphocytes. Virology (1992) 1.44
Simian virus 40 t antigen affects the sensitivity of cellular DNA synthesis to theophylline. J Virol (1979) 1.43
Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation. J Virol (1994) 1.42
Extension of JC virus host range to monkey cells by insertion of a simian virus 40 enhancer into the JC virus regulatory region. Virology (1989) 1.41
BK-related polyomavirus vasculopathy in a renal-transplant recipient. N Engl J Med (2001) 1.41
Interaction of a nuclear factor-1-like protein with the regulatory region of the human polyomavirus JC virus. J Biol Chem (1989) 1.36
Human microglia convert l-tryptophan into the neurotoxin quinolinic acid. Biochem J (1996) 1.32
Expression of multiple classes of the nuclear factor-1 family in the developing human brain: differential expression of two classes of NF-1 genes. J Neurovirol (1996) 1.32
Mechanisms of leukocyte trafficking into the CNS. J Neurovirol (2000) 1.28
Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes. J Virol (1996) 1.27
Proteolysis at the 2A/2B junction in Theiler's murine encephalomyelitis virus. Virology (1991) 1.26
Adjacent nuclear factor-1 and activator protein binding sites in the enhancer of the neurotropic JC virus. A common characteristic of many brain-specific genes. J Biol Chem (1992) 1.24
Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types. Biochem J (1997) 1.24
Relation of JC virus DNA in the cerebrospinal fluid to survival in acquired immunodeficiency syndrome patients with biopsy-proven progressive multifocal leukoencephalopathy. Ann Neurol (1999) 1.22
Homologous cellular proteins associated with simian virus 40 small T antigen and polyomavirus medium T antigen. J Virol (1988) 1.21
Progressive multifocal leukoencephalopathy: JC virus induced demyelination in the immune compromised host. J Neurovirol (2000) 1.21
Progressive multifocal leukoencephalopathy: molecular biology, pathogenesis and clinical impact. Intervirology (1997) 1.20
Failure of simian virus 40 small t antigen to disorganize actin cables in nonpermissive cell lines. J Virol (1988) 1.20
Hypothesis: "Rogue cell"-type chromosomal damage in lymphocytes is associated with infection with the JC human polyoma virus and has implications for oncopenesis. Proc Natl Acad Sci U S A (1996) 1.17
Relapsing and remitting human immunodeficiency virus-associated leukoencephalomyelopathy. Ann Neurol (1992) 1.17
Human embryonic kidney cells: stable transformation with an origin-defective simian virus 40 DNA and use as hosts for human papovavirus replication. Mol Cell Biol (1984) 1.16
Progressive multifocal leukoencephalopathy: investigation of three cases using in situ hybridization with JC virus biotinylated DNA probe. Ann Neurol (1985) 1.15
Interaction of simian virus 40 small-T antigen produced in bacteria with 56K and 32K proteins of animal cells. J Virol (1985) 1.13
Mutational analysis of simian virus 40 small-t antigen. J Virol (1990) 1.13
Evaluation of the role of cytokine activation in the multiplication of JC virus (JCV) in human fetal glial cells. J Neurovirol (1995) 1.12
The efficacy of nucleoside analogs against JC virus multiplication in a persistently infected human fetal brain cell line. J Neurovirol (1998) 1.11
Association of simian virus 40 small-t antigen with the 61-kilodalton component of a cellular protein complex. J Virol (1990) 1.11
Progressive multifocal leukoencephalopathy: JC virus detection by in situ hybridization compared with immunohistochemistry. Neurology (1986) 1.10
In vitro generation and transplantation of precursor-derived human dopamine neurons. J Neurosci Res (2001) 1.09
AIDS- and non-AIDS-related PML association with distinct p53 polymorphism. Neurology (2000) 1.08
Identification of an activity that interacts with the 3'-untranslated region of c-myc mRNA and the role of its target sequence in mediating rapid mRNA degradation. J Biol Chem (1994) 1.08
JC virus-induced owl monkey glioblastoma cells in culture: biological properties associated with the viral early gene product. Virology (1984) 1.08
Simian virus 40 small-t antigen binds two zinc ions. J Virol (1993) 1.04
Comparison of the serology, transforming ability, and polypeptide composition of human papovaviruses isolated from urine. J Virol (1976) 1.04
The Tikhoff-Linberg procedure: report of ten patients and presentation of a modified technique for tumors of the proximal humerus. Surgery (1985) 1.03
Transfection of human fetal glial cells with molecularly cloned JCV DNA. Prog Clin Biol Res (1983) 1.02
In vivo and in vitro infection of the astrocyte by HIV-1. Adv Neuroimmunol (1994) 1.01
Review: JC virus infection of lymphocytes--revisited. J Infect Dis (1997) 1.01
JC virus multiplication in human hematopoietic progenitor cells requires the NF-1 class D transcription factor. J Virol (2001) 1.01
The simian virus 40 small-t and large-T antigens jointly regulate cell cycle reentry in human fibroblasts. J Virol (1999) 1.00
Viral variant nucleotide sequences help expose leukocytic positioning in the JC virus pathway to the CNS. J Leukoc Biol (1999) 1.00
Simian virus 40 small-t antigen stimulates viral DNA replication in permissive monkey cells. J Virol (1994) 0.99
Cell cycle progression in monkey cells expressing simian virus 40 small t antigen from adenovirus vectors. J Virol (1998) 0.98
Resistance of Salmonella typhimurium mutants to galactose death. J Bacteriol (1969) 0.97
JC virus infection in cells from lymphoid tissue. Dev Biol Stand (1998) 0.97
Stages of restricted HIV-1 infection in astrocyte cultures derived from human fetal brain tissue. J Neurovirol (2000) 0.97
Progressive multifocal leukoencephalopathy in HIV-1-infected children. AIDS (1992) 0.97
Simian virus 40 small-t antigen-induced theophylline resistance is not mediated by cyclic AMP. J Virol (1985) 0.96
Varicella-zoster virus infection of human astrocytes, Schwann cells, and neurons. Virology (1990) 0.96
Effect of zinc ions on the biochemical behavior of simian virus 40 small-t antigen expressed in bacteria. J Virol (1992) 0.96
Human immunodeficiency virus type 1 infection of the brain. Clin Microbiol Rev (1993) 0.94
HIV-associated dementia. Science (2000) 0.93
Owl monkey astrocytoma cells in culture spontaneously produce infectious JC virus which demonstrates altered biological properties. J Virol (1987) 0.93
Identification of the human papovavirus T antigen and comparison with the simian virus 40 protein a. Virology (1977) 0.93
SV40 antitumor sera that directly immunoprecipitate small-t-associated cellular proteins. Virology (1981) 0.93
Simian virus 40 small-t does not transactivate RNA polymerase II promoters in virus infections. J Virol (1991) 0.92
Early appearance of type II astrocytes in developing human fetal brain. Brain Res (1988) 0.92
Human fetal Schwann cells support JC virus multiplication. J Virol (1991) 0.90
Comparison of pain, motion, and edema after modified radical mastectomy vs. local excision with axillary dissection and radiation. Breast Cancer Res Treat (1992) 0.90
A rapid method for in situ hybridization for viral DNA in brain biopsies from patients with AIDS. AIDS (1989) 0.90
Differences in NMDA receptor expression during human development determine the response of neurons to HIV-tat-mediated neurotoxicity. Neurotox Res (2010) 0.90
High titers of antibodies to two human polyomaviruses, JCV and BKV, correlate with increased frequency of chromosomal damage in human lymphocytes. Cancer Lett (1996) 0.90
JC virus T protein expression in owl monkey tumor cell lines. Prog Clin Biol Res (1983) 0.89
SV40 17K protein is associated with two cellular proteins. Cold Spring Harb Symp Quant Biol (1980) 0.89
Presence in growth-arrested cells of cellular proteins that interact with simian virus 40 small-t antigen. J Virol (1982) 0.89