Published in J Virol on September 01, 1986
Polyomavirus small t antigen: overproduction in bacteria, purification, and utilization for monoclonal and polyclonal antibody production. J Virol (1986) 2.27
Purification and functional properties of simian virus 40 large and small T antigens overproduced in insect cells. J Virol (1988) 1.14
Signaling from polyomavirus middle T and small T defines different roles for protein phosphatase 2A. Mol Cell Biol (1998) 0.94
Monoclonal antibody analysis of simian virus 40 small t-antigen expression in infected and transformed cells. J Virol (1989) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis. J Biol Chem (1977) 72.51
SV40-transformed simian cells support the replication of early SV40 mutants. Cell (1981) 34.67
Construction and analysis of viable deletion mutants of simian virus 40. J Virol (1976) 9.11
Cell-free translation of simian virus 40 early messenger RNA coding for viral T-antigen. Proc Natl Acad Sci U S A (1977) 6.57
Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells. Cell (1978) 5.23
DNA infectivity and the induction of host DNA synthesis with temperature-sensitive mutants of simian virus 40. J Virol (1975) 5.22
New region of the simian virus 40 genome required for efficient viral transformation. Proc Natl Acad Sci U S A (1978) 4.24
The roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells. Cell (1979) 3.57
Nuclear location of the putative transforming protein of avian myelocytomatosis virus. Cell (1982) 3.51
Amino acid sequence homology between polyoma and SV40 tumour antigens deduced from nucleotide sequences. Nature (1978) 3.11
The display of microtubules in transformed cells. Cell (1977) 3.04
Identification with cellular microtubules of one of the co-assemlbing microtubule-associated proteins. Cell (1979) 2.64
Comparisons of two early gene functions essential for transformation in polyoma virus and SV-40. Virology (1979) 2.64
Cellular proteins associated with simian virus 40 early gene products in newly infected cells. J Virol (1979) 2.44
Microtubule assembly and nucleation. Int Rev Cytol (1978) 2.41
Monoclonal antibodies to baculovirus structural proteins: determination of specificities by Western blot analysis. Virology (1983) 2.28
Properties of simian virus 40 small t antigen overproduced in bacteria. J Virol (1981) 2.08
Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins. J Virol (1984) 2.02
Growth control in simian virus 40-transformed rat cells: temperature-independent expression of the transformed phenotype in tsA transformants derived by agar selection. J Virol (1978) 1.81
Effect of alkylation on the physical properties of simian virus 40 T-antigen species. J Virol (1979) 1.77
Role of small t antigen in the acute transforming activity of SV40. Cell (1982) 1.76
Simian virus 40 small-t protein is required for loss of actin cable networks in rat cells. J Virol (1980) 1.68
Association of cellular 56,000- and 32,000-molecular-weight protein with BK virus and polyoma virus t-antigens. J Virol (1981) 1.63
Purification of biologically active simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A (1983) 1.61
Growth state of the cell early after infection with simian virus 40 determines whether the maintenance of transformation will be A-gene dependent or independent. J Virol (1979) 1.51
Simian virus 40 gene A regulation of cellular DNA synthesis. II. In nonpermissive cells. J Virol (1981) 1.51
Simian virus 40 t antigen affects the sensitivity of cellular DNA synthesis to theophylline. J Virol (1979) 1.43
Requirement for the large T and small T proteins of SV40 in the maintenance of the transformed state. Cold Spring Harb Symp Quant Biol (1980) 1.43
MAP2 (microtubule-associated protein 2). Cell Muscle Motil (1984) 1.16
Variable defectiveness for lytic growth of the dl 54/59 mutants of simian virus 40. J Virol (1980) 1.15
Identification and initial characterization of a new low-molecular-weight virus-encoded T antigen in a line of simian virus 40-transformed cells. J Virol (1980) 1.11
Monoclonal antibody to simian virus 40 small t. J Virol (1984) 1.08
Localization of the simian virus 40 small t antigen in the nucleus and cytoplasm of monkey and mouse cells. J Virol (1984) 1.07
High-level synthesis in Escherichia coli of the SV40 small-t antigen under control of the bacteriophage lambda pL promoter. Gene (1982) 1.02
Presence in growth-arrested cells of cellular proteins that interact with simian virus 40 small-t antigen. J Virol (1982) 0.89
Rapid and sensitive quantitative immunoassay for the large simian virus 40 T antigen. J Virol (1981) 0.88
Stimulation of host centriolar antigen in TC7 cells by simian virus 40: requirement for RNA and protein syntheses and an intact simian virus 40 small-t gene function. J Virol (1982) 0.88
SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell (1988) 12.69
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev (1994) 8.92
Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell (1997) 8.28
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell (1993) 7.19
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell (1998) 6.73
Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell (1991) 6.55
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell (1989) 6.43
Immunoaffinity chromatography of proteins. Methods Enzymol (1974) 6.40
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell (1997) 5.92
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science (2001) 5.58
E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell (1996) 5.26
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem (1996) 5.15
Binding and modulation of p53 by p300/CBP coactivators. Nature (1997) 5.12
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci U S A (1994) 5.11
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell (1992) 5.05
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell (2001) 5.05
T antigen repression of SV40 early transcription from two promoters. Cell (1981) 4.83
An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci U S A (1996) 4.57
Identification of a growth suppression domain within the retinoblastoma gene product. Genes Dev (1992) 4.56
A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature (1995) 4.40
In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature (2000) 4.38
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell (1991) 4.24
Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell (1994) 4.01
Spinocerebellar ataxia type 5 in a family descended from the grandparents of President Lincoln maps to chromosome 11. Nat Genet (1994) 3.89
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature (1996) 3.88
SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family. Cell (1989) 3.88
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell (1998) 3.86
Genetic analysis of BRCA1 function in a defined tumor cell line. Mol Cell (1999) 3.83
Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med (2000) 3.72
Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion. Cell (1980) 3.62
Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation. Cell (1990) 3.61
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature (2000) 3.48
Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell (1991) 3.47
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300. Proc Natl Acad Sci U S A (1996) 3.43
Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity. Mol Cell (2001) 3.43
Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature (1995) 3.39
lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Cell (1987) 3.33
Infectious C-type virus isolated from a baboon placenta. Nature (1974) 3.32
Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cells. Cell (1988) 3.29
p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell (1998) 3.27
Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev (1996) 3.24
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev (2000) 3.24
E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell (1994) 3.24
Radioimmunoassay of mammalian type C viral proteins. I. Species specific reactions of murine and feline viruses. J Immunol (1972) 3.23
The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. Cell (1990) 3.19
The p400 complex is an essential E1A transformation target. Cell (2001) 3.05
E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev (1994) 3.05
Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes Dev (1995) 3.02
An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120. Cell (1989) 2.78
Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell (1995) 2.70
Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science (1993) 2.70
Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc Natl Acad Sci U S A (1995) 2.70
The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway. Genes Dev (1996) 2.58
TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest. Cell (1993) 2.57
BRCA1 is a component of the RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A (1997) 2.55
Control of Saccharomyces cerevisiae 2microN DNA replication by cell division cycle genes that control nuclear DNA replication. J Mol Biol (1977) 2.55
Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev (1999) 2.51
E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control. Mol Cell (2000) 2.48
Identification of regions of the SV40 genome which contain preferred SV40 T antigen-binding sites. Cell (1976) 2.47
Association of p300 and CBP with simian virus 40 large T antigen. Mol Cell Biol (1996) 2.40
Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins. Science (1992) 2.39
Effect of limited homology on gene conversion in a Saccharomyces cerevisiae plasmid recombination system. Mol Cell Biol (1988) 2.37
Specific enzymatic dephosphorylation of the retinoblastoma protein. Mol Cell Biol (1993) 2.37
Relationship of oligomerization to enzymatic and DNA-binding properties of the SV40 large T antigen. Cell (1982) 2.35
Thermolabile T (tumor) antigen from cells transformed by a temperature-sensitive mutant of simian virus 40. Proc Natl Acad Sci U S A (1975) 2.32
Definition of the minimal simian virus 40 large T antigen- and adenovirus E1A-binding domain in the retinoblastoma gene product. Mol Cell Biol (1990) 2.27
Mitotic gene conversion lengths, coconversion patterns, and the incidence of reciprocal recombination in a Saccharomyces cerevisiae plasmid system. Mol Cell Biol (1986) 2.27
Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiation. Nature (1998) 2.25
The subcellular localization of E2F-4 is cell-cycle dependent. Proc Natl Acad Sci U S A (1997) 2.24
A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting. Genes Dev (1998) 2.19
Interaction of partially purified simian virus 40 T antigen with circular viral DNA molecules. Proc Natl Acad Sci U S A (1975) 2.17
Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens. Proc Natl Acad Sci U S A (1987) 2.15
SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen. Cell (1987) 2.13
Interaction between human cyclin A and adenovirus E1A-associated p107 protein. Science (1992) 2.13
Radioimmunoassay of mammalian type C viral proteins. 3. Detection of viral antigen in normal murine cells and tissues. J Exp Med (1973) 2.13
Expansions of CAG repeat tracts are frequent in a yeast mutant defective in Okazaki fragment maturation. Hum Mol Genet (1998) 2.06
Endogenous type C virus from a cat cell clone with properties distinct from previously described feline type C virus. Virology (1973) 2.05
Inheritance of the 2 micrometer m DNA plasmid from Saccharomyces. Genetics (1977) 2.01
trans-activation of RNA polymerase II and III promoters by SV40 small t antigen. Cell (1988) 1.98
The transcription factor E2F-1 is a downstream target of RB action. Mol Cell Biol (1995) 1.97
The retinoblastoma-susceptibility gene product becomes phosphorylated in multiple stages during cell cycle entry and progression. Proc Natl Acad Sci U S A (1992) 1.94
Location of BRCA1 in human breast and ovarian cancer cells. Science (1996) 1.88
Multiple members of the E2F transcription factor family are the products of oncogenes. Proc Natl Acad Sci U S A (1995) 1.86
Partial purification and characterization of the SV40 T antigen. Cell (1974) 1.81
Isolation of a condensed, intracellular form of the 2-micrometer DNA plasmid of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1979) 1.81
SV40 T antigen: partial purification and properties. Cold Spring Harb Symp Quant Biol (1975) 1.80
Mammalian cells in culture frequently release type C viruses. Science (1973) 1.79
Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6. Proc Natl Acad Sci U S A (1998) 1.77
The simian virus 40 large T antigen. A lot packed into a little. Mol Biol Med (1987) 1.77
Role of small t antigen in the acute transforming activity of SV40. Cell (1982) 1.76
p19ARF targets certain E2F species for degradation. Proc Natl Acad Sci U S A (2001) 1.75
Protein kinase activity associated with simian virus 40 T antigen. Proc Natl Acad Sci U S A (1979) 1.72
Deoxyribonucleic acid polymerase III of Escherichia coli. Purification and properties. J Biol Chem (1975) 1.72
Synthesis of simian virus 40 t antigen in Escherichia coli. Proc Natl Acad Sci U S A (1979) 1.70
Measurements of the molecular size of the simian virus 40 large T antigen. J Virol (1978) 1.70
A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth. J Virol (1986) 1.68