Published in J Biol Chem on October 10, 1981
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Genetic dissection of Drosophila adenylate cyclase. Proc Natl Acad Sci U S A (1985) 1.21
Role and mechanisms of action of acetylcholine in the regulation of rat cholangiocyte secretory functions. J Clin Invest (1997) 1.20
Temporal asymmetry in activation of Aplysia adenylyl cyclase by calcium and transmitter may explain temporal requirements of conditioning. Proc Natl Acad Sci U S A (1992) 0.99
Activation of Neurospora crassa soluble adenylate cyclase by calmodulin. Biochem J (1984) 0.95
GTP is not required for calmodulin stimulation of bovine brain adenylate cyclase. Proc Natl Acad Sci U S A (1982) 0.83
Effect of trifluoperazine on rabbit cortical collecting tubular response to vasopressin. J Physiol (1986) 0.80
Identification of the catalytic subunit of brain adenylate cyclase: a calmodulin binding protein of 135 kDa. Proc Natl Acad Sci U S A (1985) 0.79
Activation and stabilization of the catalytic unit of adenylate cyclase. Biochem J (1985) 0.77
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Inhibition of calmodulin-dependent myosin light-chain kinase by growth-hormone-releasing factor and vasoactive intestinal peptide. Biochem J (1994) 0.75
The WD repeat: a common architecture for diverse functions. Trends Biochem Sci (1999) 8.39
Solution structure of a calmodulin-target peptide complex by multidimensional NMR. Science (1992) 6.16
The beta gamma subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. Nature (1987) 6.05
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G protein beta gamma subunits. Annu Rev Pharmacol Toxicol (1997) 3.50
Identification of the NH2-terminal blocking group of calcineurin B as myristic acid. FEBS Lett (1982) 3.42
Solution structure of calcium-free calmodulin. Nat Struct Biol (1995) 3.36
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Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains. Nat Struct Biol (2001) 3.18
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry (1992) 3.05
Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. Proc Natl Acad Sci U S A (1992) 2.98
Purification of cyclic 3',5'-nucleotide phosphodiesterase inhibitory protein by affinity chromatography on activator protein coupled to Sepharose. Biochemistry (1978) 2.89
Purification and characterization of smooth muscle myosin light chain kinase. J Biol Chem (1981) 2.84
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Changes in D(--)-beta-hydroxybutyric dehydrogenase activity during brain maturation in the rat. J Biol Chem (1967) 2.55
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G-protein beta gamma-subunits activate the cardiac muscarinic K+-channel via phospholipase A2. Nature (1989) 2.14
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Positive cooperative binding of calcium to bovine brain calmodulin. Biochemistry (1980) 2.08
Dual calcium ion regulation of calcineurin by calmodulin and calcineurin B. Biochemistry (1994) 2.02
Effects of cations on affinity of calmodulin for calcium: ordered binding of calcium ions allows the specific activation of calmodulin-stimulated enzymes. Biochemistry (1981) 1.87
Functional domain structure of calcineurin A: mapping by limited proteolysis. Biochemistry (1989) 1.86
Activation of calcineurin by limited proteolysis. Proc Natl Acad Sci U S A (1983) 1.85
Physical and immunological characterization of a guanine nucleotide-binding protein purified from bovine cerebral cortex. J Biol Chem (1985) 1.81
Embryonic stem cells lacking a functional inhibitory G-protein subunit (alpha i2) produced by gene targeting of both alleles. Proc Natl Acad Sci U S A (1991) 1.74
G0 is a major growth cone protein subject to regulation by GAP-43. Nature (1990) 1.72
Transient cardiac expression of constitutively active Galphaq leads to hypertrophy and dilated cardiomyopathy by calcineurin-dependent and independent pathways. Proc Natl Acad Sci U S A (1998) 1.68
Calmodulin. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 1.65
Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin. J Biol Chem (1992) 1.64
Inhibition of neutrophil chemokinesis on vitronectin by inhibitors of calcineurin. Science (1992) 1.53
Cloning of human calcineurin A: evidence for two isozymes and identification of a polyproline structural domain. Proc Natl Acad Sci U S A (1989) 1.52
Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit. Biochemistry (1996) 1.48
G alpha(o) is necessary for muscarinic regulation of Ca2+ channels in mouse heart. Proc Natl Acad Sci U S A (1997) 1.48
Specificity of G protein beta and gamma subunit interactions. J Biol Chem (1992) 1.46
Dilated cardiomyopathy in two transgenic mouse lines expressing activated G protein alpha(q): lack of correlation between phospholipase C activation and the phenotype. J Mol Cell Cardiol (2001) 1.43
Atrial natriuretic factor gene expression in ventricles of rats with spontaneous biventricular hypertrophy. J Clin Invest (1988) 1.42
Sites for Galpha binding on the G protein beta subunit overlap with sites for regulation of phospholipase Cbeta and adenylyl cyclase. J Biol Chem (1998) 1.36
Go, a guanine nucleotide-binding protein: immunohistochemical localization in rat brain resembles distribution of second messenger systems. Proc Natl Acad Sci U S A (1986) 1.35
Superoxide dismutase protects calcineurin from inactivation. Nature (1996) 1.32
Subunit structure and catalytic properties of bovine brain Ca2+-dependent cyclic nucleotide phosphodiesterase. Biochemistry (1979) 1.29
Folding a WD repeat propeller. Role of highly conserved aspartic acid residues in the G protein beta subunit and Sec13. J Biol Chem (1998) 1.28
Physical and functional properties of adenylate cyclase from mature rat testis. J Biol Chem (1978) 1.26
The processive degradation of individual polyribonucleotide chains. II. Micrococcus lysodeikticus polynucleotide phosphorylase. J Biol Chem (1968) 1.26
Isolation and characterization of bovine brain calcineurin: a calmodulin-stimulated protein phosphatase. Methods Enzymol (1983) 1.23
Dephosphorylation of phosphopeptides by calcineurin (protein phosphatase 2B). Eur J Biochem (1994) 1.23
Calmodulin binding by calcineurin. Ligand-induced renaturation of protein immobilized on nitrocellulose. J Biol Chem (1987) 1.22
Purification of smooth muscle myosin light-chain kinase. Methods Enzymol (1982) 1.21
In vitro synthesis of G protein beta gamma dimers. J Biol Chem (1991) 1.21
Interaction of calmodulin with myosin light chain kinase and cAMP-dependent protein kinase in bovine brain. J Biol Chem (1981) 1.21
Identification, characterization, and functional correlation of calmodulin-dependent protein phosphatase in sperm. J Cell Biol (1988) 1.19
Calcium modulation of inositol 1,4,5-trisphosphate-induced calcium release from neuroblastoma x glioma hybrid (NG108-15) microsomes. J Biol Chem (1986) 1.17
The effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding. J Biol Chem (1989) 1.16
Multiple forms of adenylate cyclase. Adv Cyclic Nucleotide Res (1978) 1.16
Phosphorylase kinase from rabbit skeletal muscle: identification of the calmodulin-binding subunits. Eur J Biochem (1980) 1.16
A convenient method for the preparation of primer-dependent polynucleotide phosphorylase from Micrococcus lysodeikticus. Biochem Biophys Res Commun (1967) 1.14
Agonist and antagonist properties of calmodulin fragments. J Biol Chem (1984) 1.13
Ultrastructural immunocytochemical localization of calmodulin in cultured cells. J Histochem Cytochem (1983) 1.13
Identification of cDNA encoding an additional alpha subunit of a human GTP-binding protein: expression of three alpha i subtypes in human tissues and cell lines. Proc Natl Acad Sci U S A (1988) 1.13
Isotope-edited multidimensional NMR of calcineurin B in the presence of the non-deuterated detergent CHAPS. J Biomol NMR (1993) 1.11
The role of alpha-lactalbumin in lactose synthetase. Biochem Biophys Res Commun (1970) 1.10
Subunit interactions of native and ADP-ribosylated alpha 39 and alpha 41, two guanine nucleotide-binding proteins from bovine cerebral cortex. J Biol Chem (1986) 1.09
The structure of the B subunit of calcineurin. Eur J Biochem (1984) 1.09
Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel. Proc Natl Acad Sci U S A (1988) 1.07
Mutagenesis of the amino terminus of the alpha subunit of the G protein Go. In vitro characterization of alpha o beta gamma interactions. J Biol Chem (1992) 1.06
The proteolytic conversion of polynucleotide phosphorylase to a primer-dependent form. J Biol Chem (1969) 1.06
Increase in the size of soluble brain adenylate cyclase with activation by guanosine 5'-(beta, gamma-imino)triphosphate. J Biol Chem (1980) 1.05
The size of adenylate cyclase. J Biol Chem (1974) 1.05
Molecular cloning and characterization of cDNA encoding the GTP-binding protein alpha i and identification of a related protein, alpha h. Proc Natl Acad Sci U S A (1986) 1.05
Conformations of the alpha 39, alpha 41, and beta.gamma components of brain guanine nucleotide-binding proteins. Analysis by limited proteolysis. J Biol Chem (1986) 1.04
Interaction of 125I-labeled Ca2+-dependent regulator protein with cyclic nucleotide phosphodiesterase and its inhibitory protein. J Biol Chem (1978) 1.04
Low affinity Ca2+-binding sites of calcineurin B mediate conformational changes in calcineurin A. Biochemistry (2000) 1.04
Development of muscarinic cholinergic inhibition of adenylate cyclase in embryonic chick heart. Its relationship to changes in the inhibitory guanine nucleotide regulatory protein. J Biol Chem (1986) 1.04
Activation of phosphorylase kinase from rabbit skeletal muscle by calmodulin and troponin. FEBS Lett (1979) 1.03
Exocytosis induction in Paramecium tetraurelia cells by exogenous phosphoprotein phosphatase in vivo and in vitro: possible involvement of calcineurin in exocytotic membrane fusion. J Cell Biol (1987) 1.03
Sites important for PLCbeta2 activation by the G protein betagamma subunit map to the sides of the beta propeller structure. J Biol Chem (1998) 1.02
Structural and functional studies of cross-linked Go protein subunits. J Biol Chem (1991) 1.02
Analysis of the physical properties and molecular modeling of Sec13: A WD repeat protein involved in vesicular traffic. Biochemistry (1996) 1.01
Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit. Cell Regul (1989) 1.00
Calcineurin A alpha (PPP3CA), calcineurin A beta (PPP3CB) and calcineurin B (PPP3R1) are located on human chromosomes 4, 10q21-->q22 and 2p16-->p15 respectively. Cytogenet Cell Genet (1996) 0.99
G-protein alpha o subunit: mutation of conserved cysteines identifies a subunit contact surface and alters GDP affinity. Proc Natl Acad Sci U S A (1993) 0.99
Serine/threonine phosphatases in the nervous system. Curr Opin Neurobiol (1991) 0.98
Genetically engineered calmodulins differentially activate target enzymes. J Biol Chem (1986) 0.98
1H, 13C, 15N nuclear magnetic resonance backbone assignments and secondary structure of human calcineurin B. Biochemistry (1994) 0.97
Cardiac myocytes express mRNA for ten RGS proteins: changes in RGS mRNA expression in ventricular myocytes and cultured atria. FEBS Lett (1998) 0.97
Reversible and irreversible activation of cyclic nucleotide phosphodiesterase: separation of the regulatory and catalytic domains by limited proteolysis. Adv Cyclic Nucleotide Protein Phosphorylation Res (1984) 0.97
Reactive sulfhydryl groups of alpha 39, a guanine nucleotide-binding protein from brain. Location and function. J Biol Chem (1987) 0.96
Properties of the separated catalytic and regulatory units of brain adenylate cyclase. Proc Natl Acad Sci U S A (1980) 0.95
Promotion of the GTP-liganded state of the Go alpha protein by deletion of the C terminus. J Biol Chem (1992) 0.95