P W Rigby

Author PubWeight™ 320.46‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol 1977 205.11
2 Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40. Proc Natl Acad Sci U S A 1975 7.57
3 Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes Dev 1988 7.52
4 Negative regulation of viral enhancers in undifferentiated embryonic stem cells. Cell 1985 5.88
5 McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning. Nucleic Acids Res 1988 5.76
6 A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature 1990 4.69
7 Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell 1996 4.55
8 Activation of mouse genes in transformed cells. Cell 1983 3.85
9 Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev 1991 3.46
10 The regulation of myogenin gene expression during the embryonic development of the mouse. Genes Dev 1993 3.15
11 Isolation and characterization of an alphoid centromeric repeat family from the human Y chromosome. J Mol Biol 1985 2.39
12 Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes Dev 1991 2.20
13 The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development 1991 2.17
14 Gene duplication in experimental enzyme evolution. Nature 1974 2.16
15 Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse. Nature 1984 2.13
16 An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell 1987 1.96
17 Transcripts regulated during normal embryonic development and oncogenic transformation share a repetitive element. Cell 1983 1.94
18 A role for the TATA-box-binding protein component of the transcription factor IID complex as a general RNA polymerase III transcription factor. Proc Natl Acad Sci U S A 1992 1.85
19 A fragment of the SV40 large T-antigen gene transforms. Nature 1982 1.82
20 Regulation of RNA polymerase III transcription in response to F9 embryonal carcinoma stem cell differentiation. Cell 1989 1.81
21 Cloning and characterization of the integrated viral DNA from three lines of SV40-transformed mouse cells. Cell 1981 1.72
22 A BAC transgenic analysis of the Mrf4/Myf5 locus reveals interdigitated elements that control activation and maintenance of gene expression during muscle development. Development 2001 1.54
23 Fate of viral DNA in nonpermissive cells infected with simian virus 40. Proc Natl Acad Sci U S A 1981 1.51
24 Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature 1999 1.50
25 Does simian virus 40 DNA integrate into cellular DNA during productive infection? J Virol 1978 1.48
26 The construction of cosmid libraries of eukaryotic DNA using the Homer series of vectors. Nucleic Acids Res 1982 1.47
27 Ribitol dehydrogenase from Klebsiella aerogenes. Purification and subunit structure. Biochem J 1974 1.39
28 Mapping of mutational alterations in DNA with S1 nuclease: the location of deletions, insertions and temperature-sensitive mutations in SV40. Cold Spring Harb Symp Quant Biol 1975 1.39
29 Regulation of RNA polymerase III transcription in response to Simian virus 40 transformation. EMBO J 1990 1.31
30 Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis. Dev Biol 2001 1.28
31 Derivatives of Moloney murine sarcoma virus capable of being transcribed in embryonal carcinoma stem cells have gained a functional Sp1 binding site. J Virol 1991 1.23
32 The expression of Myf5 in the developing mouse embryo is controlled by discrete and dispersed enhancers specific for particular populations of skeletal muscle precursors. Development 2000 1.22
33 Cloning vectors derived from animal viruses. J Gen Virol 1983 1.22
34 Cosmid clones derived from both euchromatic and heterochromatic regions of the human Y chromosome. EMBO J 1984 1.21
35 Structure and synthesis of a simian virus 40 super T-antigen. J Virol 1982 1.21
36 T antigens of SV40-transformed cells. Cold Spring Harb Symp Quant Biol 1980 1.20
37 The embryonal carcinoma stem cell Ela-like activity involves a differentiation-regulated transcription factor. Nucleic Acids Res 1990 1.16
38 Construction of intergeneric hybrids using bacteriophage P1CM: transfer of the Klebsiella aerogenes ribitol dehydrogenase gene to Escherichia coli. J Bacteriol 1976 1.15
39 A comparison of wild-type and mutant ribitol dehydrogenases from Klebsiella aerogenes. Biochem J 1974 1.12
40 Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting. Nucleic Acids Res 2001 1.12
41 Expression and function of Pax 1 during development of the pectoral girdle. Development 1994 1.11
42 Functional analysis of a simian virus 40 super T-antigen. J Virol 1982 1.11
43 Regional localization of 3 Y-derived sequences on the human X and Y chromosomes. Ann Hum Genet 1984 1.09
44 The structure and expression of the preproenkephalin gene. Nucleic Acids Res 1982 1.06
45 SV40 and polyoma viruses: their analysis by deoxyribonucleic acid recombination in vitro and their use as vectors in eukaryotic systems. Biochem Soc Symp 1979 0.99
46 Expression of the L14 lectin during mouse embryogenesis suggests multiple roles during pre- and post-implantation development. Development 1992 0.98
47 Effect of passage in culture on a clone of BALB/c 3T3 cells transformed by simian virus 40. J Virol 1976 0.97
48 Transcripts from an aberrantly re-arranged human T-cell receptor beta-chain gene. EMBO J 1985 0.96
49 Cloning of DNA fragments from the left end of the adenovirus type 12 genome: transformation by cloned early region 1. J Gen Virol 1982 0.93
50 The class I major histocompatibility antigen gene activated in a line of SV40-transformed mouse cells is H-2Dd, not Qa/Tla. Nature 1985 0.93
51 The regulation of SV40 early gene expression in embryonal carcinoma stem cells--faithful transcriptional regulation in vitro. Nucleic Acids Res 1988 0.91
52 Multiple positive and negative regulatory elements in the promoter of the mouse homeobox gene Hoxb-4. Mol Cell Biol 1994 0.91
53 The gene encoding the calcium binding protein calcyclin is expressed at sites of exocytosis in the mouse. J Cell Sci 1993 0.91
54 The structure and expression of the integrated viral DNA in mouse cells transformed by simian virus 40. Proc R Soc Lond B Biol Sci 1980 0.89
55 The use of histone as a facilitator to improve the efficiency of retroviral gene transfer. Nucleic Acids Res 1996 0.88
56 Transcriptional regulation during somitogenesis. Curr Top Dev Biol 2000 0.87
57 Sequences and factors required for the F9 embryonal carcinoma stem cell E1a-like activity. Mol Cell Biol 1991 0.87
58 Simian virus 40 specific cytotoxic lymphocyte clones localize two distinct TSTA sites on cells synthesizing a 48 kD SV40 T antigen. Virology 1984 0.87
59 The oncogenic circle closes. Nature 1982 0.87
60 The TATA-binding protein is a general transcription factor for RNA polymerase III. J Cell Sci Suppl 1992 0.87
61 The branchial Hox code and its implications for gene regulation, patterning of the nervous system and head evolution. Development 1991 0.85
62 The regulation of gene expression in murine teratocarcinoma cells. Cold Spring Harb Symp Quant Biol 1985 0.82
63 Activation of endogenous retroviral transcription in SV40-transformed mouse cells. Nucleic Acids Res 1991 0.81
64 The regulation of cellular transcription by Simian virus 40 large T-antigen. Proc R Soc Lond B Biol Sci 1985 0.80
65 High efficiency gene transfer into mammalian cells. Philos Trans R Soc Lond B Biol Sci 1984 0.79
66 Isolation of developmentally regulated genes by differential display screening of cDNA libraries. Nucleic Acids Res 1998 0.79
67 Evidence against expression of an endogenous murine leukemia virus causing cellular resistance to lysis by activated macrophages. J Immunol 1989 0.77
68 Oct-3 and mammalian development: correction of discussion. Science 1992 0.75
69 Progress maintained in molecular biology. Nature 1972 0.75
70 The activation of cellular genes in transformed cells. Philos Trans R Soc Lond B Biol Sci 1984 0.75
71 Oct-3 and the beginning of mammalian development. Science 1991 0.75
72 Hybrid oncogenes. A multi-purpose tool for studying multi-step processes. Nature 1985 0.75
73 The use of cDNA cloning techniques to isolate genes activated in tumour cells. Haematol Blood Transfus 1983 0.75
74 Reporter genes for the study of transcriptional regulation in transgenic mouse embryos. Methods Mol Biol 1999 0.75
75 The detection of cellular transforming genes. Nature 1981 0.75