Published in Nature on July 01, 1999
Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells. J Cell Biol (2005) 3.96
The formation of skeletal muscle: from somite to limb. J Anat (2003) 3.37
MicroRNA-206: the skeletal muscle-specific myomiR. Biochim Biophys Acta (2008) 2.64
Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition. Am J Pathol (2002) 2.17
A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb. Genes Dev (2006) 2.02
Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer. Cancer Res (2010) 1.74
Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. Am J Pathol (2003) 1.49
Tbx4 and tbx5 acting in connective tissue are required for limb muscle and tendon patterning. Dev Cell (2010) 1.22
Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness. PLoS One (2011) 1.19
Six proteins regulate the activation of Myf5 expression in embryonic mouse limbs. Proc Natl Acad Sci U S A (2007) 1.14
Microarray analysis of the temporal response of skeletal muscle to methylprednisolone: comparative analysis of two dosing regimens. Physiol Genomics (2007) 1.10
Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development. BMC Dev Biol (2008) 1.08
Hedgehog can drive terminal differentiation of amniote slow skeletal muscle. BMC Dev Biol (2004) 1.08
A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiation. Genes Dev (2009) 1.04
Meox homeodomain proteins are required for Bapx1 expression in the sclerotome and activate its transcription by direct binding to its promoter. Mol Cell Biol (2004) 0.95
Myotome meanderings. Cellular morphogenesis and the making of muscle. EMBO Rep (2003) 0.95
Regulation of myogenic differentiation in the developing limb bud. J Anat (2003) 0.93
Lack of the mesodermal homeodomain protein MEOX1 disrupts sclerotome polarity and leads to a remodeling of the cranio-cervical joints of the axial skeleton. Dev Biol (2009) 0.92
Transient activation of meox1 is an early component of the gene regulatory network downstream of hoxa2. Mol Cell Biol (2011) 0.90
Myogenesis and muscle regeneration. Histochem Cell Biol (2012) 0.88
Morphogenesis and evolution of vertebrate appendicular muscle. J Anat (2001) 0.85
Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity. Genes Dev (2012) 0.84
Other model organisms for sarcomeric muscle diseases. Adv Exp Med Biol (2008) 0.83
Mutation in MEOX1 gene causes a recessive Klippel-Feil syndrome subtype. BMC Genet (2013) 0.83
Mesodermal gene expression during the embryonic and larval development of the articulate brachiopod Terebratalia transversa. Evodevo (2015) 0.80
NDR Kinases Are Essential for Somitogenesis and Cardiac Looping during Mouse Embryonic Development. PLoS One (2015) 0.79
Different requirements for Wnt signaling in tongue myogenic subpopulations. J Dent Res (2015) 0.76
EMBO Workshop Report: Molecular genetics of muscle development and neuromuscular diseases Kloster Irsee, Germany, September 26-October 1, 1999. EMBO J (2000) 0.76
Notchless is required for axial skeleton formation in mice. PLoS One (2014) 0.76
Identification and characterization of a Mef2 transcriptional activator in schistosome parasites. PLoS Negl Trop Dis (2012) 0.76
Shaping muscle bioarchitecture for the fin to limb transition. Bioarchitecture (2012) 0.75
Strain-Dependent Gene Expression during Mouse Embryonic Palate Development. J Dev Biol (2015) 0.75
Fine-tuning the onset of myogenesis by homeobox proteins that interact with the Myf5 limb enhancer. Biol Open (2015) 0.75
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development (1996) 9.58
Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40. Proc Natl Acad Sci U S A (1975) 7.57
Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes Dev (1988) 7.52
Negative regulation of viral enhancers in undifferentiated embryonic stem cells. Cell (1985) 5.88
McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning. Nucleic Acids Res (1988) 5.76
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret. Nature (1994) 5.61
Bmp4 is required for the generation of primordial germ cells in the mouse embryo. Genes Dev (1999) 5.19
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature (1990) 4.69
Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell (1996) 4.55
Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development (1995) 4.38
Activation of mouse genes in transformed cells. Cell (1983) 3.85
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev (1991) 3.46
The regulation of myogenin gene expression during the embryonic development of the mouse. Genes Dev (1993) 3.15
The medial ganglionic eminence gives rise to a population of early neurons in the developing cerebral cortex. J Neurosci (1999) 3.03
Neurodevelopment of children exposed in utero to phenytoin and carbamazepine monotherapy. JAMA (1994) 2.82
Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas. Genesis (2000) 2.48
Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development (1992) 2.43
Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation. Nat Genet (1997) 2.41
Isolation and characterization of an alphoid centromeric repeat family from the human Y chromosome. J Mol Biol (1985) 2.39
DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction. Development (1992) 2.38
Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature (1996) 2.35
Inhibition in the human motor cortex is reduced just before a voluntary contraction. Neurology (1999) 2.26
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes Dev (1991) 2.20
SPTLC1 is mutated in hereditary sensory neuropathy, type 1. Nat Genet (2001) 2.20
The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development (1991) 2.17
Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene. Mol Cell Biol (1997) 2.16
Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development (1995) 2.16
Gene duplication in experimental enzyme evolution. Nature (1974) 2.16
Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development. Development (1998) 2.15
Activation of a Qa/Tla class I major histocompatibility antigen gene is a general feature of oncogenesis in the mouse. Nature (1984) 2.13
Induction of the zebrafish ventral brain and floorplate requires cyclops/nodal signalling. Nature (1998) 2.10
Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature (1996) 2.09
Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium. Development (1997) 2.05
Cortical-basal ganglionic degeneration. Neurology (1990) 2.04
Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development. Development (1996) 1.96
An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell (1987) 1.96
Corticospinal projections to upper limb motoneurones in humans. J Physiol (1992) 1.95
Transcripts regulated during normal embryonic development and oncogenic transformation share a repetitive element. Cell (1983) 1.94
Organizer-specific homeobox genes in Xenopus laevis embryos. Science (1991) 1.90
Expansion of Pdx1-expressing pancreatic epithelium and islet neogenesis in transgenic mice overexpressing transforming growth factor alpha. Gastroenterology (1999) 1.88
A role for the TATA-box-binding protein component of the transcription factor IID complex as a general RNA polymerase III transcription factor. Proc Natl Acad Sci U S A (1992) 1.85
A fragment of the SV40 large T-antigen gene transforms. Nature (1982) 1.82
Regulation of RNA polymerase III transcription in response to F9 embryonal carcinoma stem cell differentiation. Cell (1989) 1.81
Locus unlinked to alpha-fetoprotein under the control of the murine raf and Rif genes. Proc Natl Acad Sci U S A (1984) 1.80
Prognostic significance of DNA ploidy and proliferative index (MIB-1 index) in gastrointestinal stromal tumors. Hum Pathol (1997) 1.78
Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development (1996) 1.75
Cloning and characterization of the integrated viral DNA from three lines of SV40-transformed mouse cells. Cell (1981) 1.72
An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2). Mol Cell Biol (1998) 1.72
Synaptic connections from large muscle afferents to the motoneurons of various leg muscles in man. Exp Brain Res (1984) 1.71
Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis. Dev Biol (1994) 1.71
Molecular mechanisms of Spemann's organizer formation: conserved growth factor synergy between Xenopus and mouse. Genes Dev (1995) 1.71
Mechanism of the silent period following transcranial magnetic stimulation. Evidence from epidural recordings. Exp Brain Res (1999) 1.68
Pancreatic beta cell-specific transcription of the pdx-1 gene. The role of conserved upstream control regions and their hepatic nuclear factor 3beta sites. J Biol Chem (2000) 1.64
Wnt8 is required in lateral mesendodermal precursors for neural posteriorization in vivo. Development (2001) 1.58
Parietal Pick's disease mimicking cortical-basal ganglionic degeneration. Neurology (1994) 1.55
A BAC transgenic analysis of the Mrf4/Myf5 locus reveals interdigitated elements that control activation and maintenance of gene expression during muscle development. Development (2001) 1.54
Differential utilization of the same reading frame in a Xenopus homeobox gene encodes two related proteins sharing the same DNA-binding specificity. EMBO J (1988) 1.54
Murine Cdx-4 bears striking similarities to the Drosophila caudal gene in its homeodomain sequence and early expression pattern. Mech Dev (1993) 1.54
XIHbox 8, an endoderm-specific Xenopus homeodomain protein, is closely related to a mammalian insulin gene transcription factor. Mol Endocrinol (1994) 1.54
Vertebrate homeodomain proteins: families of region-specific transcription factors. Trends Biochem Sci (1989) 1.52
Fate of viral DNA in nonpermissive cells infected with simian virus 40. Proc Natl Acad Sci U S A (1981) 1.51
Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. Genes Dev (2001) 1.51
Corticospinal projections to lower limb motoneurons in man. Exp Brain Res (1992) 1.48
Does simian virus 40 DNA integrate into cellular DNA during productive infection? J Virol (1978) 1.48
Regulatory regions driving developmental and tissue-specific expression of the essential pancreatic gene pdx1. Dev Biol (2001) 1.47
The construction of cosmid libraries of eukaryotic DNA using the Homer series of vectors. Nucleic Acids Res (1982) 1.47
Fgf-8 determines rostral-caudal polarity in the first branchial arch. Development (1999) 1.46
Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system. Development (1999) 1.46
Reduction of insulin gene transcription in HIT-T15 beta cells chronically exposed to a supraphysiologic glucose concentration is associated with loss of STF-1 transcription factor expression. Proc Natl Acad Sci U S A (1995) 1.45
Ipsilateral fast corticospinal pathways do not account for recovery in stroke. Ann Neurol (1992) 1.44
Two regulatory domains flank the mouse H19 gene. Mol Cell Biol (1988) 1.44
Evidence that a long latency stretch reflex in humans is transcortical. J Physiol (1992) 1.43
Relationship between EPSP shape and cross-correlation profile explored by computer simulation for studies on human motoneurons. Exp Brain Res (1982) 1.41
Are spinal "presynaptic" inhibitory mechanisms suppressed in spasticity? J Neurol Sci (1972) 1.40
Ribitol dehydrogenase from Klebsiella aerogenes. Purification and subunit structure. Biochem J (1974) 1.39
Mapping of mutational alterations in DNA with S1 nuclease: the location of deletions, insertions and temperature-sensitive mutations in SV40. Cold Spring Harb Symp Quant Biol (1975) 1.39
Effects of extensor and flexor group I afferent volleys on the excitability of individual soleus motoneurones in man. J Neurol Neurosurg Psychiatry (1977) 1.38
Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter. Genesis (2000) 1.37
Characteristics of postsynaptic potentials produced in single human motoneurons by homonymous group 1 volleys. Exp Brain Res (1982) 1.32
Nodal induces ectopic goosecoid and lim1 expression and axis duplication in zebrafish. Development (1995) 1.32
Corticospinal projections to upper and lower limb spinal motoneurons in man. Electroencephalogr Clin Neurophysiol (1990) 1.31
Regulation of RNA polymerase III transcription in response to Simian virus 40 transformation. EMBO J (1990) 1.31
Stretch reflexes in the upper limb of spastic man. J Neurol Neurosurg Psychiatry (1971) 1.30
Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function. Development (2000) 1.29
Differentiation of new insulin-producing cells is induced by injury in adult pancreatic islets. Endocrinology (1997) 1.28
Hedgehog signalling is required for maintenance of myf5 and myoD expression and timely terminal differentiation in zebrafish adaxial myogenesis. Dev Biol (2001) 1.28
Targeted disruption of the galanin gene reduces the number of sensory neurons and their regenerative capacity. Proc Natl Acad Sci U S A (2000) 1.27
Derivatives of Moloney murine sarcoma virus capable of being transcribed in embryonal carcinoma stem cells have gained a functional Sp1 binding site. J Virol (1991) 1.23
The expression of Myf5 in the developing mouse embryo is controlled by discrete and dispersed enhancers specific for particular populations of skeletal muscle precursors. Development (2000) 1.22
Cloning vectors derived from animal viruses. J Gen Virol (1983) 1.22
Multipotential progenitors of the mammalian enteric nervous system capable of colonising aganglionic bowel in organ culture. Development (1999) 1.22
Cosmid clones derived from both euchromatic and heterochromatic regions of the human Y chromosome. EMBO J (1984) 1.21
Structure and synthesis of a simian virus 40 super T-antigen. J Virol (1982) 1.21
Functional characterization of the transactivation properties of the PDX-1 homeodomain protein. Mol Cell Biol (1997) 1.21
T antigens of SV40-transformed cells. Cold Spring Harb Symp Quant Biol (1980) 1.20
Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis. Development (1999) 1.20
Conduction velocity in the proximal segments of a motor nerve in the Guillain-Barré syndrome. J Neurol Neurosurg Psychiatry (1976) 1.17
The embryonal carcinoma stem cell Ela-like activity involves a differentiation-regulated transcription factor. Nucleic Acids Res (1990) 1.16
Spasticity, decerebrate rigidity and the clasp-knife phenomenon: an experimental study in the cat. Brain (1972) 1.16