Published in Nature on February 14, 1984
Organization and regulation of an operon that encodes a sporulation-essential sigma factor in Bacillus subtilis. J Bacteriol (1987) 4.79
Epidermal growth factor and oncogenes induce transcription of the same cellular mRNA in rat fibroblasts. EMBO J (1985) 3.60
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest (2011) 2.90
Mouse major histocompatibility class I gene expression begins at midsomite stage and is inducible in earlier-stage embryos by interferon. Proc Natl Acad Sci U S A (1985) 2.56
Cell-cycle-specific cDNAs from mammalian cells temperature sensitive for growth. Proc Natl Acad Sci U S A (1984) 2.02
Secretion of HLA-A and -B antigens via an alternative RNA splicing pathway. J Exp Med (1986) 1.89
Transcriptional regulation of two serum-induced RNAs in mouse fibroblasts: equivalence of one species to B2 repetitive elements. Mol Cell Biol (1985) 1.73
DNA sequence of the mouse H-2Dd transplantation antigen gene. Proc Natl Acad Sci U S A (1985) 1.65
Differential expression of the human gonadotropin alpha gene in ectopic and eutopic cells. Mol Cell Biol (1985) 1.53
Regulation of RNA polymerase III transcription in response to Simian virus 40 transformation. EMBO J (1990) 1.31
The tumor promoter phorbol 12-myristate 13-acetate induces a program of altered gene expression similar to that induced by platelet-derived growth factor and transforming oncogenes. Proc Natl Acad Sci U S A (1986) 1.21
Functional role of HLA class I cell-surface molecules in human T-lymphocyte activation and proliferation. Proc Natl Acad Sci U S A (1986) 1.19
Sequences coding for part of oncogene-induced transin are highly conserved in a related rat gene. Nucleic Acids Res (1987) 1.17
Adenovirus type 2 preferentially stimulates polymerase III transcription of Alu elements by relieving repression: a potential role for chromatin. Mol Cell Biol (1995) 1.09
Snail represses the splicing regulator epithelial splicing regulatory protein 1 to promote epithelial-mesenchymal transition. J Biol Chem (2012) 1.06
Class I genes and molecules: an update. Immunology (1986) 1.05
T3 delta pre-mRNA is transcribed from a non-TATA promoter and is alternatively spliced in human T cells. EMBO J (1986) 1.05
Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts. J Clin Invest (1988) 1.02
Alternative protein products with different carboxyl termini from a single class I gene, H-2Kb. Proc Natl Acad Sci U S A (1986) 1.00
Transcriptional induction of the ubiquitin gene during herpes simplex virus infection is dependent upon the viral immediate-early protein ICP4. Nucleic Acids Res (1987) 1.00
RNAs containing B2 repeated sequences are transcribed in the early stages of mouse embryogenesis. EMBO J (1985) 0.95
Alternative processing of H-2Dd pre-mRNAs results in membrane expression of differentially phosphorylated protein products. EMBO J (1986) 0.95
Intramolecular recombination between partially homologous sequences in Escherichia coli and Xenopus laevis oocytes. Proc Natl Acad Sci U S A (1987) 0.95
Alternative splicing in the 5' moiety of the H-2Kd gene transcript. EMBO J (1984) 0.93
Characterization of highly and moderately repetitive 500 bp Eco RI fragments from Xenopus laevis DNA. Nucleic Acids Res (1984) 0.93
Keratin gene expression in simian virus 40-transformed human keratinocytes. Proc Natl Acad Sci U S A (1985) 0.92
Unusual RNA splicing generates a secreted form of HLA-A2 in a mutagenized B lymphoblastoid cell line. EMBO J (1985) 0.92
Fine mapping of epitopes by intradomain Kd/Dd recombinants. J Exp Med (1987) 0.92
Selective and synchronous activation of early-S-phase replicons of Ehrlich ascites cells. Mol Cell Biol (1993) 0.91
Malignant transformation and tumor promoter treatment increase levels of a transcript for a secreted glycoprotein. Mol Cell Biol (1985) 0.90
A gene sequence expressed only in undifferentiated EC, EK cells and testes. EMBO J (1984) 0.90
Functional heterogeneity in allospecific cytotoxic T lymphocyte clones. I. CTL clones express strong anti-self suppressive activity. J Exp Med (1984) 0.87
Reduced tumorigenicity of a spontaneous mouse lung carcinoma following H-2 gene transfection. Proc Natl Acad Sci U S A (1987) 0.86
Expression of class I and II major histocompatibility complex antigens in Wilms' tumour and normal developing human kidney. Br J Cancer (1988) 0.84
Differential expression of H-2Dd and H-2Ld histocompatibility antigens. J Exp Med (1985) 0.83
Expression of a mouse long terminal repeat is cell cycle-linked. Proc Natl Acad Sci U S A (1985) 0.83
A putative transmembrane protein with histidine-rich charge clusters encoded in the H-2K/tw5 region of mice. Mol Cell Biol (1990) 0.81
Activation of endogenous retroviral transcription in SV40-transformed mouse cells. Nucleic Acids Res (1991) 0.81
Tumour immunology: a review. J R Soc Med (1984) 0.80
Expression of structurally diverse Qa-2-encoded molecules on the surface of cloned cytotoxic T lymphocytes. J Exp Med (1984) 0.80
Differential Hm antigen expression on EC cells and early differentiated derivatives. EMBO J (1985) 0.77
The structure of HSAG-1, a middle repetitive genetic element which elicits a leukemia-related cellular surface antigen. Nucleic Acids Res (1986) 0.76
Non-cytotoxic antibodies in chronic lymphocytic leukaemia. J Clin Pathol (1987) 0.75
Detection of alternative splicing during epithelial-mesenchymal transition. J Vis Exp (2014) 0.75
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
Biochemical method for mapping mutational alterations in DNA with S1 nuclease: the location of deletions and temperature-sensitive mutations in simian virus 40. Proc Natl Acad Sci U S A (1975) 7.57
Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes Dev (1988) 7.52
Negative regulation of viral enhancers in undifferentiated embryonic stem cells. Cell (1985) 5.88
McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning. Nucleic Acids Res (1988) 5.76
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo. Nature (1990) 4.69
Know your neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell (1996) 4.55
Do formal advance directives affect resuscitation decisions and the use of resources for seriously ill patients? SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. J Clin Ethics (1994) 4.23
Activation of mouse genes in transformed cells. Cell (1983) 3.85
Absence of the type I IFN system in EC cells: transcriptional activator (IRF-1) and repressor (IRF-2) genes are developmentally regulated. Cell (1990) 3.58
Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Genes Dev (1991) 3.46
Cardiac stress protein elevation 24 hours after brief ischemia or heat stress is associated with resistance to myocardial infarction. Circulation (1993) 3.27
The regulation of myogenin gene expression during the embryonic development of the mouse. Genes Dev (1993) 3.15
T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol. Nature (1992) 3.12
Depletion and disruption of dietary fibre. Effects on satiety, plasma-glucose, and serum-insulin. Lancet (1977) 3.08
The role of radiotracer imaging in Parkinson disease. Neurology (2005) 3.02
In a minority of gay men, sexual risk practice indicates strategic positioning for perceived risk reduction rather than unbridled sex. AIDS Care (2002) 3.01
Synthesis and characterization of phosphorescent cyclometalated iridium complexes. Inorg Chem (2001) 2.94
Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript. J Virol (1990) 2.87
Highly phosphorescent bis-cyclometalated iridium complexes: synthesis, photophysical characterization, and use in organic light emitting diodes. J Am Chem Soc (2001) 2.61
PINK1 protein in normal human brain and Parkinson's disease. Brain (2006) 2.49
Isolation and characterization of an alphoid centromeric repeat family from the human Y chromosome. J Mol Biol (1985) 2.39
Situs revisited: imaging of the heterotaxy syndrome. Radiographics (1999) 2.33
Large DNA restriction fragment polymorphism in the Mycobacterium avium-M. intracellulare complex: a potential epidemiologic tool. J Clin Microbiol (1993) 2.25
The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo. Proc Natl Acad Sci U S A (1993) 2.20
Scheduled change of antibiotic classes: a strategy to decrease the incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med (1997) 2.20
Multiple spatially specific enhancers are required to reconstruct the pattern of Hox-2.6 gene expression. Genes Dev (1991) 2.20
The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo. Development (1991) 2.17
Gene duplication in experimental enzyme evolution. Nature (1974) 2.16
Explicit and implicit neural mechanisms for processing of social information from facial expressions: a functional magnetic resonance imaging study. Hum Brain Mapp (2000) 2.04
Assessment of enzyme immunoassay and immunofluorescence tests for detection of Chlamydia trachomatis. J Clin Microbiol (1987) 2.03
An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell (1987) 1.96
Transcripts regulated during normal embryonic development and oncogenic transformation share a repetitive element. Cell (1983) 1.94
Novel cell lines display properties of nociceptive sensory neurons. Proc Biol Sci (1990) 1.89
Chemotaxis of macrophages is abolished in the Wiskott-Aldrich syndrome. Br J Haematol (1998) 1.87
Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. Curr Biol (1994) 1.87
A role for the TATA-box-binding protein component of the transcription factor IID complex as a general RNA polymerase III transcription factor. Proc Natl Acad Sci U S A (1992) 1.85
Developmental and transformation-sensitive expression of the Sparc gene on mouse chromosome 11. EMBO J (1986) 1.83
A fragment of the SV40 large T-antigen gene transforms. Nature (1982) 1.82
Regulation of RNA polymerase III transcription in response to F9 embryonal carcinoma stem cell differentiation. Cell (1989) 1.81
The severity of alcohol dependence questionnaire: its use, reliability and validity. Br J Addict (1983) 1.76
Switching transgene expression in the brain using an adenoviral tetracycline-regulatable system. Nat Biotechnol (1998) 1.75
Cloning and characterization of the integrated viral DNA from three lines of SV40-transformed mouse cells. Cell (1981) 1.72
The chaperonin containing t-complex polypeptide 1 (TCP-1). Multisubunit machinery assisting in protein folding and assembly in the eukaryotic cytosol. Eur J Biochem (1995) 1.70
Octamer motif mediates transcriptional repression of HSV immediate-early genes and octamer-containing cellular promoters in neuronal cells. Neuron (1990) 1.65
Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis. J Biol Chem (2000) 1.65
Difficulty in diagnosing double-chambered right ventricle in adults. Am J Cardiol (2001) 1.64
A comparison of autoanalyser methods for the estimation of glucose in blood. Clin Chim Acta (1973) 1.63
Functional wrist motion: a biomechanical study. J Hand Surg Am (1985) 1.63
The impact of nosocomial infections on patient outcomes following cardiac surgery. Chest (1997) 1.62
Expression of multiple functional chemokine receptors and monocyte chemoattractant protein-1 in human neurons. Neuroscience (2000) 1.61
Gene regulation in the magnocellular hypothalamo-neurohypophysial system. Physiol Rev (2001) 1.61
Laparoscopic management of generalized peritonitis due to perforated colonic diverticula. Am J Surg (1996) 1.60
Growth characteristics and response to growth hormone therapy in patients with hypochondroplasia: genetic linkage of the insulin-like growth factor I gene at chromosome 12q23 to the disease in a subgroup of these patients. Clin Endocrinol (Oxf) (1991) 1.60
Efficient and rapid affinity purification of proteins using recombinant fusion proteases. Biotechnology (N Y) (1994) 1.60
Human immunodeficiency virus 1. Predominance of a group-specific neutralizing epitope that persists despite genetic variation. J Exp Med (1989) 1.59
A dual-centre, cohort comparison of open, laparoscopic and robotic-assisted radical cystectomy. Int J Clin Pract (2012) 1.58
Bacterial contamination of home nebuliser. Br Med J (Clin Res Ed) (1987) 1.55
A BAC transgenic analysis of the Mrf4/Myf5 locus reveals interdigitated elements that control activation and maintenance of gene expression during muscle development. Development (2001) 1.54
The assignment of chain specificities for anti-Ia monoclonal antibodies using L cell transfectants. J Immunol (1986) 1.54
Overexpression of BMP-2 and BMP-4 alters the size and shape of developing skeletal elements in the chick limb. Mech Dev (1996) 1.54
Wiskott-Aldrich syndrome protein is necessary for efficient IgG-mediated phagocytosis. Blood (2000) 1.53
Robotic assisted radical cystectomy: short to medium-term oncologic and functional outcomes. Int J Clin Pract (2008) 1.52
Fate of viral DNA in nonpermissive cells infected with simian virus 40. Proc Natl Acad Sci U S A (1981) 1.51
Mox2 is a component of the genetic hierarchy controlling limb muscle development. Nature (1999) 1.50
Tumour necrosis factor-alpha (TNF-alpha) synthesis is associated with the skin and peripheral nerve pathology of leprosy reversal reactions. Clin Exp Immunol (1995) 1.50
The occurrence, nature and distribution of flares in a cohort of patients with systemic lupus erythematosus: a rheumatological view. Br J Rheumatol (1995) 1.49
Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701. J Biol Chem (2001) 1.49
Does simian virus 40 DNA integrate into cellular DNA during productive infection? J Virol (1978) 1.48
Pathogenicity of cyathostome infection. Vet Parasitol (1999) 1.47
The construction of cosmid libraries of eukaryotic DNA using the Homer series of vectors. Nucleic Acids Res (1982) 1.47
Interns as teachers of medical students: a pilot programme. Ir J Med Sci (2010) 1.46
Impaired ability of schizophrenics, relative to manics or depressives, to appreciate social knowledge about their culture. Br J Psychiatry (1990) 1.46
Guidelines for transesophageal echocardiography in children. J Am Soc Echocardiogr (1993) 1.45
Dehydration-induced proteome changes in the rat hypothalamo-neurohypophyseal system. Endocrinology (2007) 1.45
Involvement of bone morphogenetic protein-4 and bone morphogenetic protein-7 in the differentiation of the adrenergic phenotype in developing sympathetic neurons. Development (1996) 1.44
Urinary 17-hydroxycorticosteroids measured by gas-liquid chromatography. J Endocrinol (1966) 1.44
Loss of heterozygosity and microsatellite instability at the MLL locus are common in childhood acute leukemia, but not in infant acute leukemia. Blood (1999) 1.42
Wiskott-Aldrich syndrome protein (WASp) is a binding partner for c-Src family protein-tyrosine kinases. Curr Biol (1996) 1.42
Analysis of antigen-specific, Ig-restricted cell-free material made by I-J+ Ly-1 cells (Ly-1 TsiF) that induces Ly-2+ cells to express suppressive activity. Eur J Immunol (1981) 1.42
A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells. Nucleic Acids Res (1992) 1.41
Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. Development (1994) 1.40
Opposing actions of STAT-1 and STAT-3 on the Bcl-2 and Bcl-x promoters. Cell Death Differ (2000) 1.40
Ribitol dehydrogenase from Klebsiella aerogenes. Purification and subunit structure. Biochem J (1974) 1.39
Long-term follow-up of children after repair of atrial septal defects. Cleve Clin J Med (1994) 1.39
Epithelioid angiosarcoma of the orbit presenting as Tolosa-Hunt syndrome. A clinicopathologic case report with review of the literature. Ophthalmology (1983) 1.39
Mapping of mutational alterations in DNA with S1 nuclease: the location of deletions, insertions and temperature-sensitive mutations in SV40. Cold Spring Harb Symp Quant Biol (1975) 1.39
The s(p)elling of apo(p)tosis. Nature (1995) 1.38
Psychiatric disorders in Parkinson's disease. Br J Hosp Med (1992) 1.38
Amplification and rearrangement of integrated SV40 DNA sequences accompany the selection of anchorage-independent transformed mouse cells. Cell (1980) 1.38
Chronic debilitating fatigue in Irish general practice: a survey of general practitioners' experience. Br J Gen Pract (1997) 1.34
The octamer-binding protein Oct-2 represses HSV immediate-early genes in cell lines derived from latently infectable sensory neurons. Neuron (1991) 1.34
Combined test of anterior pituitary function in children. Arch Dis Child (1978) 1.34
Analysis of an antigen-specific H-2-restricted cell-free products(s) made by "I-J-" Ly-2 cells (Ly-2 TsF) that suppresses Ly-2 cell-depleted spleen cell activity. Eur J Immunol (1981) 1.34
Opposing actions of STAT-1 and STAT-3. Growth Factors (2005) 1.33