Published in J Mol Appl Genet on January 01, 1981
Regeneration of insertionally inactivated streptococcal DNA fragments after excision of transposon Tn916 in Escherichia coli: strategy for targeting and cloning of genes from gram-positive bacteria. J Bacteriol (1984) 6.82
Transposon mutagenesis of type III group B Streptococcus: correlation of capsule expression with virulence. Proc Natl Acad Sci U S A (1987) 3.99
Streptococcus faecalis sex pheromone (cAM373) also produced by Staphylococcus aureus and identification of a conjugative transposon (Tn918). J Bacteriol (1985) 3.84
A yeast gene important for protein assembly into the endoplasmic reticulum and the nucleus has homology to DnaJ, an Escherichia coli heat shock protein. J Cell Biol (1989) 3.56
Sequence analysis of termini of conjugative transposon Tn916. J Bacteriol (1988) 3.22
Genetic organization of the bacterial conjugative transposon Tn916. J Bacteriol (1988) 3.18
Homology of a transferable tetracycline resistance determinant of Clostridium difficile with Streptococcus (Enterococcus) faecalis transposon Tn916. Antimicrob Agents Chemother (1987) 2.43
A conjugative transposon (Tn919) in Streptococcus sanguis. Infect Immun (1985) 2.41
Essential sites at transposon Tn 10 termini. Proc Natl Acad Sci U S A (1984) 1.55
In vivo and in vitro synthesis of Escherichia coli maltose-binding protein under regulatory control of the lacUV5 promoter-operator. J Bacteriol (1985) 1.34
Expression of polyoma early gene products in E. coli. Nucleic Acids Res (1985) 1.29
Increased production of the siderophore anguibactin mediated by pJM1-like plasmids in Vibrio anguillarum. Infect Immun (1988) 1.28
Cocrystals of the DNA-binding domain of phage 434 repressor and a synthetic phage 434 operator. Proc Natl Acad Sci U S A (1984) 1.24
Transposon Tn916 mutagenesis in Bacillus anthracis. Infect Immun (1988) 1.23
Cloning and characterization of the tetracycline resistance determinant of and several promoters from within the conjugative transposon Tn919. Appl Environ Microbiol (1988) 1.19
SecB-independent export of Escherichia coli ribose-binding protein (RBP): some comparisons with export of maltose-binding protein (MBP) and studies with RBP-MBP hybrid proteins. J Bacteriol (1990) 1.05
Retroregulation of the bacteriophage lambda int gene: limited secondary degradation of the RNase III-processed transcript. J Bacteriol (1989) 0.96
Wild-type bacteriophage T4 is restricted by the lambda rex genes. J Virol (1987) 0.95
GAL4-VP16 is an unusually potent transcriptional activator. Nature (1988) 16.53
Deletion analysis of GAL4 defines two transcriptional activating segments. Cell (1987) 14.13
Construction of plasmids carrying the cI gene of bacteriophage lambda. Proc Natl Acad Sci U S A (1976) 13.10
Specific DNA binding of GAL4, a positive regulatory protein of yeast. Cell (1985) 10.25
Gene regulation by proteins acting nearby and at a distance. Nature (1986) 9.71
A new class of yeast transcriptional activators. Cell (1987) 9.53
Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1981) 9.45
Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli. Gene (1983) 8.85
A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell (1985) 8.30
A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res (1989) 8.06
Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG. Mol Cell Biol (1984) 7.83
Negative effect of the transcriptional activator GAL4. Nature (1988) 7.15
Autoregulation and function of a repressor in bacteriophage lambda. Science (1976) 6.83
Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein. Science (1986) 6.79
Structure of the lambda operators. Nature (1973) 6.66
How the lambda repressor and cro work. Cell (1980) 6.65
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 6.23
Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature (1974) 6.22
Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit beta-globin. Cell (1980) 6.20
Mechanism of action of the lexA gene product. Proc Natl Acad Sci U S A (1981) 6.13
Cooperative binding of lambda repressors to sites separated by integral turns of the DNA helix. Cell (1986) 5.81
DNA recognition by GAL4: structure of a protein-DNA complex. Nature (1992) 5.60
Multiple repressor binding at the operators in bacteriophage lambda. Proc Natl Acad Sci U S A (1973) 5.15
Interactions between DNA-bound repressors govern regulation by the lambda phage repressor. Proc Natl Acad Sci U S A (1979) 5.02
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proc Natl Acad Sci U S A (1984) 4.90
Novel properties of a restriction endonuclease isolated from Haemophilus parahaemolyticus. Proc Natl Acad Sci U S A (1976) 4.74
Recognition of a DNA operator by the repressor of phage 434: a view at high resolution. Science (1988) 4.60
A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature (1990) 4.57
lambda Repressor and cro--components of an efficient molecular switch. Nature (1981) 4.52
The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80. Cell (1987) 4.49
Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus. J Virol (2001) 4.48
Mutants of GAL4 protein altered in an activation function. Cell (1987) 4.44
Mechanism of action of the cro protein of bacteriophage lambda. Proc Natl Acad Sci U S A (1978) 4.34
Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda. Cell (1975) 4.28
Control elements in the DNA of bacteriophage lambda. Cold Spring Harb Symp Quant Biol (1974) 4.23
Specific binding of the lambda phage repressor to lambda DNA. Nature (1967) 4.23
A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene. Nature (1985) 4.08
Gene regulation at the right operator (OR) of bacteriophage lambda. II. OR1, OR2, and OR3: their roles in mediating the effects of repressor and cro. J Mol Biol (1980) 4.02
Transcription in yeast activated by a putative amphipathic alpha helix linked to a DNA binding unit. Nature (1988) 3.93
Maximizing gene expression on a plasmid using recombination in vitro. Cell (1978) 3.84
Repressor structure and the mechanism of positive control. Cell (1983) 3.82
GAL4 activates gene expression in mammalian cells. Cell (1988) 3.81
GAL4 activates transcription in Drosophila. Nature (1988) 3.73
Cooperative DNA binding of the yeast transcriptional activator GAL4. Proc Natl Acad Sci U S A (1988) 3.72
The lambda repressor contains two domains. Proc Natl Acad Sci U S A (1979) 3.68
A general method for maximizing the expression of a cloned gene. Proc Natl Acad Sci U S A (1979) 3.67
GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell (1988) 3.67
An amino-terminal fragment of GAL4 binds DNA as a dimer. J Mol Biol (1989) 3.65
Gene regulation at the right operator (OR) bacteriophage lambda. I. OR3 and autogenous negative control by repressor. J Mol Biol (1980) 3.64
Generating yeast transcriptional activators containing no yeast protein sequences. Nature (1991) 3.21
Lambda repressor turns off transcription of its own gene. Proc Natl Acad Sci U S A (1975) 3.12
The lexA gene product represses its own promoter. Proc Natl Acad Sci U S A (1980) 3.03
Structure of the repressor-operator complex of bacteriophage 434. Nature (1987) 3.00
How different eukaryotic transcriptional activators can cooperate promiscuously. Nature (1990) 2.91
Contact with a component of the polymerase II holoenzyme suffices for gene activation. Cell (1995) 2.85
Regulatory functions of the lambda repressor reside in the amino-terminal domain. Nature (1979) 2.77
Determinants of binding-site specificity among yeast C6 zinc cluster proteins. Science (1993) 2.57
DNA loops induced by cooperative binding of lambda repressor. Nature (1986) 2.50
Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro. Nature (1987) 2.49
An activator target in the RNA polymerase II holoenzyme. Mol Cell (1998) 2.37
Quantitation of putative activator-target affinities predicts transcriptional activating potentials. EMBO J (1996) 2.34
GAL11P: a yeast mutation that potentiates the effect of weak GAL4-derived activators. Cell (1990) 2.26
The operators controlled by the lambda phage repressor. Proc Natl Acad Sci U S A (1968) 2.21
An HMG-like protein that can switch a transcriptional activator to a repressor. Nature (1994) 2.18
Promoters are in the operators in phage lambda. Nature (1974) 2.16
A potent GAL4 derivative activates transcription at a distance in vitro. Science (1990) 2.15
Structure of the operator-binding domain of bacteriophage lambda repressor: implications for DNA recognition and gene regulation. Cold Spring Harb Symp Quant Biol (1983) 2.15
Chromatin components as part of a putative transcriptional repressing complex. Proc Natl Acad Sci U S A (1998) 2.14
A new-specificity mutant of 434 repressor that defines an amino acid-base pair contact. Nature (1987) 2.13
Yeast activators stimulate plant gene expression. Nature (1988) 2.13
DNA twisting and the affinity of bacteriophage 434 operator for bacteriophage 434 repressor. Proc Natl Acad Sci U S A (1988) 2.08
Changing the binding specificity of a repressor by redesigning an alpha-helix. Nature (1985) 2.08
Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro. Mol Cell Biol (1989) 2.06
A phage repressor-operator complex at 7 A resolution. Nature (1985) 2.00
Gene regulation at the right operator (OR) of bacteriophage lambda. III. lambda repressor directly activates gene transcription. J Mol Biol (1980) 1.99
Structure of a phage 434 Cro/DNA complex. Nature (1988) 1.98
Cleavage of the lambda and P22 repressors by recA protein. J Biol Chem (1982) 1.97
Gene activation by recruitment of the RNA polymerase II holoenzyme. Genes Dev (1996) 1.90
Expression of the human fibroblast interferon gene in Escherichia coli. Proc Natl Acad Sci U S A (1980) 1.84
Serum interleukin 4 and interleukin 10 levels in patients with chronic hepatitis C virus infection. J Hepatol (1997) 1.82
In vitro repression of RNA synthesis by purified lambda phage repressor. Nat New Biol (1971) 1.82
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function. Proc Natl Acad Sci U S A (1987) 1.81
Cellular immune responses against hepatitis C virus: the evidence base 2002. Clin Exp Immunol (2002) 1.81
Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells. Proc Natl Acad Sci U S A (1982) 1.80
Synthesis of simian virus 40 t antigen in Escherichia coli. Proc Natl Acad Sci U S A (1979) 1.70
New eukaryotic transcriptional repressors. Nature (1993) 1.68
How lambda repressor and lambda Cro distinguish between OR1 and OR3. Cell (1986) 1.68
A single glutamic acid residue plays a key role in the transcriptional activation function of lambda repressor. Cell (1989) 1.67
Completed DNA sequences and organization of repressor-binding sites in the operators of phage lambda. J Mol Biol (1977) 1.66
Regulation of damage-inducible genes in Escherichia coli. J Mol Biol (1982) 1.63
Substituting an alpha-helix switches the sequence-specific DNA interactions of a repressor. Cell (1984) 1.63
RNA polymerase II holoenzyme recruitment is sufficient to remodel chromatin at the yeast PHO5 promoter. Cell (1997) 1.63
p53 and K-RAS alterations in pancreatic epithelial cell lesions. Oncogene (1993) 1.62
Telomere looping permits gene activation by a downstream UAS in yeast. Nature (2001) 1.61
Homologous interactions of lambda repressor and lambda Cro with the lambda operator. Cell (1986) 1.58
Sites of contact between lambda operators and lambda repressor. Nucleic Acids Res (1977) 1.58
Overproduction and purification of protein P6 of Bacillus subtilis phage phi 29: role in the initiation of DNA replication. Nucleic Acids Res (1985) 1.56
Delineation of two functional regions of transcription factor TFIIB. Proc Natl Acad Sci U S A (1993) 1.55