Published in Gene on November 01, 1983
Autodigestion of lexA and phage lambda repressors. Proc Natl Acad Sci U S A (1984) 5.94
Regulation of ribosomal RNA promoters with a synthetic lac operator. Proc Natl Acad Sci U S A (1984) 5.92
Strategies for achieving high-level expression of genes in Escherichia coli. Microbiol Rev (1996) 4.93
Promoters of Escherichia coli: a hierarchy of in vivo strength indicates alternate structures. EMBO J (1986) 3.89
Packaging specific segments of the Salmonella chromosome with locked-in Mud-P22 prophages. Genetics (1988) 3.33
Functional dissection of Escherichia coli promoters: information in the transcribed region is involved in late steps of the overall process. EMBO J (1986) 3.33
Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CP1. Mol Cell Biol (1990) 3.24
Degradation of sigma 32, the heat shock regulator in Escherichia coli, is governed by HflB. Proc Natl Acad Sci U S A (1995) 3.20
Construction of two Escherichia coli amber suppressor genes: tRNAPheCUA and tRNACysCUA. Proc Natl Acad Sci U S A (1986) 3.00
Control of Vibrio fischeri lux gene transcription by a cyclic AMP receptor protein-luxR protein regulatory circuit. J Bacteriol (1988) 3.00
Development of a genetic system for Geobacter sulfurreducens. Appl Environ Microbiol (2001) 2.91
Regulatory RNA as mediator in GacA/RsmA-dependent global control of exoproduct formation in Pseudomonas fluorescens CHA0. J Bacteriol (2002) 2.86
Modulation of stability of the Escherichia coli heat shock regulatory factor sigma. J Bacteriol (1989) 2.80
Transcription-induced mutations: increase in C to T mutations in the nontranscribed strand during transcription in Escherichia coli. Proc Natl Acad Sci U S A (1996) 2.65
Overproduction and purification of the luxR gene product: Transcriptional activator of the Vibrio fischeri luminescence system. Proc Natl Acad Sci U S A (1987) 2.59
Regulation of the bgl operon of Escherichia coli by transcriptional antitermination. EMBO J (1988) 2.49
Double-stranded cleavage of T-DNA and generation of single-stranded T-DNA molecules in Escherichia coli by a virD-encoded border-specific endonuclease from Agrobacterium tumefaciens. J Bacteriol (1987) 2.48
Association of the virD2 protein with the 5' end of T strands in Agrobacterium tumefaciens. J Bacteriol (1988) 2.44
Quantitation of putative activator-target affinities predicts transcriptional activating potentials. EMBO J (1996) 2.34
TnpA product encoded by the transposable element En-1 of Zea mays is a DNA binding protein. EMBO J (1988) 2.14
Enteropathogenic Escherichia coli: identification of a gene cluster coding for bundle-forming pilus morphogenesis. J Bacteriol (1996) 2.08
Liberation of an interaction domain from the phosphotransfer region of CheA, a signaling kinase of Escherichia coli. Proc Natl Acad Sci U S A (1994) 2.06
Identification of Escherichia coli region III flagellar gene products and description of two new flagellar genes. J Bacteriol (1984) 1.99
Gateway vectors for the production of combinatorially-tagged His6-MBP fusion proteins in the cytoplasm and periplasm of Escherichia coli. Protein Sci (2005) 1.98
Immunization of mice against tetanus with fragments of tetanus toxin synthesized in Escherichia coli. Infect Immun (1987) 1.97
Expression of the nodulation gene nodA in Rhizobium meliloti and localization of the gene product in the cytosol. Proc Natl Acad Sci U S A (1986) 1.96
A 3.6-kbp segment from the vir region of Ti plasmids contains genes responsible for border-sequence-directed production of T region circles in E. coli. EMBO J (1986) 1.92
Inducible overproduction of the mouse c-myc protein in mammalian cells. Proc Natl Acad Sci U S A (1986) 1.89
Penicillin acylase from E. coli: unique gene-protein relation. Nucleic Acids Res (1986) 1.82
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function. Proc Natl Acad Sci U S A (1987) 1.81
Rhizobium meliloti nodA and nodB genes are involved in generating compounds that stimulate mitosis of plant cells. Proc Natl Acad Sci U S A (1988) 1.81
Effect of single amino acid replacements on the thermal stability of the NH2-terminal domain of phage lambda repressor. Proc Natl Acad Sci U S A (1984) 1.80
Cloning, expression, and mapping of the Aeromonas hydrophila aerolysin gene determinant in Escherichia coli K-12. J Bacteriol (1986) 1.77
Overproduction and dissection of proteins by the expression-cassette polymerase chain reaction. Proc Natl Acad Sci U S A (1990) 1.77
Bacteriophage lambda cro mutations: effects on activity and intracellular degradation. Proc Natl Acad Sci U S A (1986) 1.77
dnaA protein-regulated transcription: effects on the in vitro replication of Escherichia coli minichromosomes. EMBO J (1985) 1.77
A protein that binds to the regulatory region of the Escherichia coli ilvIH operon. J Bacteriol (1989) 1.75
Expression of tetanus toxin fragment C in E. coli: high level expression by removing rare codons. Nucleic Acids Res (1989) 1.75
Production of a polyhedral particle in Escherichia coli from a cDNA copy of the large genomic segment of bacteriophage phi 6. J Virol (1988) 1.74
Bacillus sphaericus as a mosquito pathogen: properties of the organism and its toxins. Microbiol Rev (1991) 1.71
Purification and preliminary characterization of the Escherichia coli K-12 recF protein. J Bacteriol (1990) 1.70
Multiple beta-ketothiolases mediate poly(beta-hydroxyalkanoate) copolymer synthesis in Ralstonia eutropha. J Bacteriol (1998) 1.65
Transmembrane orientation and receptor-like structure of the Rhizobium meliloti common nodulation protein NodC. EMBO J (1988) 1.65
Acinetobacter cyclohexanone monooxygenase: gene cloning and sequence determination. J Bacteriol (1988) 1.63
The cisA cistron of Bacillus subtilis sporulation gene spoIVC encodes a protein homologous to a site-specific recombinase. J Bacteriol (1990) 1.61
Cloning of the C-terminal cytoplasmic fragment of the tar protein and effects of the fragment on chemotaxis of Escherichia coli. J Bacteriol (1988) 1.60
Cross talk to the phosphate regulon of Escherichia coli by PhoM protein: PhoM is a histidine protein kinase and catalyzes phosphorylation of PhoB and PhoM-open reading frame 2. J Bacteriol (1990) 1.60
A convenient technique to compare the efficiency of promoters in Escherichia coli. Nucleic Acids Res (1985) 1.59
Exotoxin A of Pseudomonas aeruginosa: active, cloned toxin is secreted into the periplasmic space of Escherichia coli. J Bacteriol (1987) 1.58
Immunogenicity of peptide fusions to hepatitis B virus core antigen. Proc Natl Acad Sci U S A (1989) 1.57
Genetic organization of plasmid R1162 DNA involved in conjugative mobilization. J Bacteriol (1986) 1.55
Expression of the nodulation gene nod C of Rhizobium meliloti in Escherichia coli: role of the nod C gene product in nodulation. EMBO J (1985) 1.55
Essential sites at transposon Tn 10 termini. Proc Natl Acad Sci U S A (1984) 1.55
Protein RepC is involved in copy number control of the broad host range plasmid RSF1010. Proc Natl Acad Sci U S A (1985) 1.55
Cloning and sequencing of a Bacteroides ruminicola B(1)4 endoglucanase gene. J Bacteriol (1990) 1.53
Characterization of the DNA-binding properties of the polyomavirus capsid protein VP1. J Virol (1991) 1.49
Gene- and strand-specific repair in vitro: partial purification of a transcription-repair coupling factor. Proc Natl Acad Sci U S A (1991) 1.48
A cII-dependent promoter is located within the Q gene of bacteriophage lambda. Proc Natl Acad Sci U S A (1985) 1.46
Expression of the wheat mitochondrial nad3-rps12 transcription unit: correlation between editing and mRNA maturation. Plant Cell (1991) 1.45
Synthesis of pyrroloquinoline quinone in vivo and in vitro and detection of an intermediate in the biosynthetic pathway. J Bacteriol (1995) 1.43
Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier. Infect Immun (1990) 1.42
The product of the Drosophila zeste gene binds to specific DNA sequences in white and Ubx. EMBO J (1987) 1.42
Chromosomal location and structure of the operon encoding peptide-chain-release factor 2 of Escherichia coli. Proc Natl Acad Sci U S A (1988) 1.41
Role of PhoU in phosphate transport and alkaline phosphatase regulation. J Bacteriol (1992) 1.41
NH2-terminal arm of phage lambda repressor contributes energy and specificity to repressor binding and determines the effects of operator mutations. Proc Natl Acad Sci U S A (1985) 1.36
Profilins constitute a novel family of functional plant pan-allergens. J Exp Med (1992) 1.35
Hepatitis B virus polypeptide X: expression in Escherichia coli and identification of specific antibodies in sera from hepatitis B virus-infected humans. J Virol (1986) 1.35
DNA binding specificity of the Arc and Mnt repressors is determined by a short region of N-terminal residues. Proc Natl Acad Sci U S A (1989) 1.34
Additivity of mutant effects assessed by binomial mutagenesis. Proc Natl Acad Sci U S A (1993) 1.34
In vivo translation of a region within the rrnB 16S rRNA gene of Escherichia coli. J Bacteriol (1987) 1.33
Eight base changes are sufficient to convert a leucine-inserting tRNA into a serine-inserting tRNA. Proc Natl Acad Sci U S A (1992) 1.31
A new generalizable test for detection of mutations affecting Tn10 transposition. Genetics (1987) 1.31
A propionate-inducible expression system for enteric bacteria. Appl Environ Microbiol (2005) 1.30
Escherichia coli 6S RNA gene is part of a dual-function transcription unit. J Bacteriol (1985) 1.30
Mutations in bacteriophage lambda repressor that prevent RecA-mediated cleavage. J Bacteriol (1985) 1.30
Characterization of Shiga-like toxin I B subunit purified from overproducing clones of the SLT-I B cistron. Biochem J (1990) 1.30
Ethylene synthesis and regulated expression of recombinant protein in Synechocystis sp. PCC 6803. PLoS One (2012) 1.30
Replication of the broad-host-range plasmid RK2: direct measurement of intracellular concentrations of the essential TrfA replication proteins and their effect on plasmid copy number. J Bacteriol (1990) 1.29
Substrate specificity of trypsin investigated by using a genetic selection. Proc Natl Acad Sci U S A (1990) 1.29
Chicken triosephosphate isomerase complements an Escherichia coli deficiency. Proc Natl Acad Sci U S A (1985) 1.27
The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme. Proc Natl Acad Sci U S A (1996) 1.26
The dimer interfaces of protease and extra-protease domains influence the activation of protease and the specificity of GagPol cleavage. J Virol (2003) 1.25
Cocrystals of the DNA-binding domain of phage 434 repressor and a synthetic phage 434 operator. Proc Natl Acad Sci U S A (1984) 1.24
Copy-number of broad host-range plasmid R1162 is regulated by a small RNA. Nucleic Acids Res (1986) 1.24
Vaccine efficacy of Salmonella strains expressing glycoprotein 63 with different promoters. Infect Immun (1997) 1.23
Identification of hepatitis B virus polypeptides encoded by the entire pre-s open reading frame. J Virol (1985) 1.23
Identification of residues critical for metallo-beta-lactamase function by codon randomization and selection. Protein Sci (2001) 1.23
Tn10 transposition promotes RecA-dependent induction of a lambda prophage. Proc Natl Acad Sci U S A (1988) 1.23
Prediction of CsrA-regulating small RNAs in bacteria and their experimental verification in Vibrio fischeri. Nucleic Acids Res (2006) 1.23
Expression of human glutathione S-transferase 2 in Escherichia coli. Immunological comparison with the basic glutathione S-transferases isoenzymes from human liver. Biochem J (1987) 1.21
Rhizobium meliloti Fix L is an oxygen sensor and regulates R. meliloti nifA and fixK genes differently in Escherichia coli. J Bacteriol (1990) 1.21
Transcripts within the replication origin, oriC, of Escherichia coli. Nucleic Acids Res (1987) 1.21
Identification and localization of pre-s-encoded polypeptides from woodchuck and ground squirrel hepatitis viruses. J Virol (1986) 1.21
Evidence that the sigma 1 protein of reovirus serotype 3 is a multimer. J Virol (1987) 1.20
Catalytic mechanism of active-site serine beta-lactamases: role of the conserved hydroxy group of the Lys-Thr(Ser)-Gly triad. Biochem J (1994) 1.19
The 42- and 51-kilodalton mosquitocidal proteins of Bacillus sphaericus 2362: construction of recombinants with enhanced expression and in vivo studies of processing and toxicity. J Bacteriol (1990) 1.18
Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase. J Cell Biol (1991) 1.18
Nitrile-inducible gene expression in mycobacteria. Tuberculosis (Edinb) (2008) 1.18
Complete nucleotide sequence of a 16S ribosomal RNA gene from Escherichia coli. Proc Natl Acad Sci U S A (1978) 32.65
Gene organization and primary structure of a ribosomal RNA operon from Escherichia coli. J Mol Biol (1981) 29.04
GAL4-VP16 is an unusually potent transcriptional activator. Nature (1988) 16.53
Deletion analysis of GAL4 defines two transcriptional activating segments. Cell (1987) 14.13
Construction of plasmids carrying the cI gene of bacteriophage lambda. Proc Natl Acad Sci U S A (1976) 13.10
Specific DNA binding of GAL4, a positive regulatory protein of yeast. Cell (1985) 10.25
Gene regulation by proteins acting nearby and at a distance. Nature (1986) 9.71
A new class of yeast transcriptional activators. Cell (1987) 9.53
Secondary structure model for bacterial 16S ribosomal RNA: phylogenetic, enzymatic and chemical evidence. Nucleic Acids Res (1980) 9.50
Fusion of Escherichia coli lacZ to the cytochrome c gene of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1981) 9.45
Construction and fine mapping of recombinant plasmids containing the rrnB ribosomal RNA operon of E. coli. Plasmid (1981) 9.00
A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor. Cell (1985) 8.30
A vector for expressing GAL4(1-147) fusions in mammalian cells. Nucleic Acids Res (1989) 8.06
Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG. Mol Cell Biol (1984) 7.83
Complete nucleotide sequence of a 23S ribosomal RNA gene from Escherichia coli. Proc Natl Acad Sci U S A (1980) 7.80
Negative effect of the transcriptional activator GAL4. Nature (1988) 7.15
Secondary structure model for 23S ribosomal RNA. Nucleic Acids Res (1981) 7.12
Autoregulation and function of a repressor in bacteriophage lambda. Science (1976) 6.83
Separation of DNA binding from the transcription-activating function of a eukaryotic regulatory protein. Science (1986) 6.79
Structure of the lambda operators. Nature (1973) 6.66
How the lambda repressor and cro work. Cell (1980) 6.65
Plasmid vectors for the selection of promoters. Gene (1984) 6.33
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol Cell Biol (1984) 6.23
Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature (1974) 6.22
Improved methods for maximizing expression of a cloned gene: a bacterium that synthesizes rabbit beta-globin. Cell (1980) 6.20
Mechanism of action of the lexA gene product. Proc Natl Acad Sci U S A (1981) 6.13
Regulation of ribosomal RNA promoters with a synthetic lac operator. Proc Natl Acad Sci U S A (1984) 5.92
Cooperative binding of lambda repressors to sites separated by integral turns of the DNA helix. Cell (1986) 5.81
RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse. EMBO J (2001) 5.70
DNA recognition by GAL4: structure of a protein-DNA complex. Nature (1992) 5.60
Multiple repressor binding at the operators in bacteriophage lambda. Proc Natl Acad Sci U S A (1973) 5.15
Interactions between DNA-bound repressors govern regulation by the lambda phage repressor. Proc Natl Acad Sci U S A (1979) 5.02
Precise location of two promoters for the beta-lactamase gene of pBR322. S1 mapping of ribonucleic acid isolated from Escherichia coli or synthesized in vitro. J Biol Chem (1982) 4.90
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization. Proc Natl Acad Sci U S A (1984) 4.90
rII cistrons of bacteriophage T4. DNA sequence around the intercistronic divide and positions of genetic landmarks. J Mol Biol (1981) 4.76
Novel properties of a restriction endonuclease isolated from Haemophilus parahaemolyticus. Proc Natl Acad Sci U S A (1976) 4.74
Recognition of a DNA operator by the repressor of phage 434: a view at high resolution. Science (1988) 4.60
A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives. Nature (1990) 4.57
Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. Proc Natl Acad Sci U S A (2000) 4.54
lambda Repressor and cro--components of an efficient molecular switch. Nature (1981) 4.52
The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80. Cell (1987) 4.49
"ATG vectors' for regulated high-level expression of cloned genes in Escherichia coli. Gene (1985) 4.48
Mutants of GAL4 protein altered in an activation function. Cell (1987) 4.44
Mechanism of action of the cro protein of bacteriophage lambda. Proc Natl Acad Sci U S A (1978) 4.34
Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda. Cell (1975) 4.28
Control elements in the DNA of bacteriophage lambda. Cold Spring Harb Symp Quant Biol (1974) 4.23
Specific binding of the lambda phage repressor to lambda DNA. Nature (1967) 4.23
A bacterial repressor protein or a yeast transcriptional terminator can block upstream activation of a yeast gene. Nature (1985) 4.08
Gene regulation at the right operator (OR) of bacteriophage lambda. II. OR1, OR2, and OR3: their roles in mediating the effects of repressor and cro. J Mol Biol (1980) 4.02
Activity of the hybrid trp-lac (tac) promoter of Escherichia coli in Pseudomonas putida. Construction of broad-host-range, controlled-expression vectors. Gene (1983) 3.98
Transcription in yeast activated by a putative amphipathic alpha helix linked to a DNA binding unit. Nature (1988) 3.93
Maximizing gene expression on a plasmid using recombination in vitro. Cell (1978) 3.84
Repressor structure and the mechanism of positive control. Cell (1983) 3.82
GAL4 activates gene expression in mammalian cells. Cell (1988) 3.81
GAL4 activates transcription in Drosophila. Nature (1988) 3.73
Cooperative DNA binding of the yeast transcriptional activator GAL4. Proc Natl Acad Sci U S A (1988) 3.72
The lambda repressor contains two domains. Proc Natl Acad Sci U S A (1979) 3.68
A general method for maximizing the expression of a cloned gene. Proc Natl Acad Sci U S A (1979) 3.67
GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell (1988) 3.67
An amino-terminal fragment of GAL4 binds DNA as a dimer. J Mol Biol (1989) 3.65
Gene regulation at the right operator (OR) bacteriophage lambda. I. OR3 and autogenous negative control by repressor. J Mol Biol (1980) 3.64
Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I. Biochem J (1993) 3.43
Generating yeast transcriptional activators containing no yeast protein sequences. Nature (1991) 3.21
Spacing of the -10 and -35 regions in the tac promoter. Effect on its in vivo activity. J Biol Chem (1985) 3.14
Genetic variation in the human insulin gene. Science (1980) 3.13
Lambda repressor turns off transcription of its own gene. Proc Natl Acad Sci U S A (1975) 3.12
The lexA gene product represses its own promoter. Proc Natl Acad Sci U S A (1980) 3.03
Structure of the repressor-operator complex of bacteriophage 434. Nature (1987) 3.00
Sequence alignment of the G-protein coupled receptor superfamily. DNA Cell Biol (1992) 2.97
How different eukaryotic transcriptional activators can cooperate promiscuously. Nature (1990) 2.91
Contact with a component of the polymerase II holoenzyme suffices for gene activation. Cell (1995) 2.85
Regulatory functions of the lambda repressor reside in the amino-terminal domain. Nature (1979) 2.77
Characterization of cDNA coding for human factor XIIIa. Proc Natl Acad Sci U S A (1986) 2.62
Determinants of binding-site specificity among yeast C6 zinc cluster proteins. Science (1993) 2.57
DNA loops induced by cooperative binding of lambda repressor. Nature (1986) 2.50
Effect of non-contacted bases on the affinity of 434 operator for 434 repressor and Cro. Nature (1987) 2.49
An activator target in the RNA polymerase II holoenzyme. Mol Cell (1998) 2.37
Quantitation of putative activator-target affinities predicts transcriptional activating potentials. EMBO J (1996) 2.34
Toxicity of an overproduced foreign gene product in Escherichia coli and its use in plasmid vectors for the selection of transcription terminators. Gene (1984) 2.31
GAL11P: a yeast mutation that potentiates the effect of weak GAL4-derived activators. Cell (1990) 2.26
Identification of a site on 23S ribosomal RNA located at the peptidyl transferase center. Proc Natl Acad Sci U S A (1984) 2.22
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Neural BC1 RNA: cDNA clones reveal nonrepetitive sequence content. Proc Natl Acad Sci U S A (1987) 2.19
An HMG-like protein that can switch a transcriptional activator to a repressor. Nature (1994) 2.18
Promoters are in the operators in phage lambda. Nature (1974) 2.16
A potent GAL4 derivative activates transcription at a distance in vitro. Science (1990) 2.15
Structure of the operator-binding domain of bacteriophage lambda repressor: implications for DNA recognition and gene regulation. Cold Spring Harb Symp Quant Biol (1983) 2.15
Chromatin components as part of a putative transcriptional repressing complex. Proc Natl Acad Sci U S A (1998) 2.14
A new-specificity mutant of 434 repressor that defines an amino acid-base pair contact. Nature (1987) 2.13
Yeast activators stimulate plant gene expression. Nature (1988) 2.13
DNA twisting and the affinity of bacteriophage 434 operator for bacteriophage 434 repressor. Proc Natl Acad Sci U S A (1988) 2.08
Changing the binding specificity of a repressor by redesigning an alpha-helix. Nature (1985) 2.08
Activation of yeast polymerase II transcription by herpesvirus VP16 and GAL4 derivatives in vitro. Mol Cell Biol (1989) 2.06
A phage repressor-operator complex at 7 A resolution. Nature (1985) 2.00
Gene regulation at the right operator (OR) of bacteriophage lambda. III. lambda repressor directly activates gene transcription. J Mol Biol (1980) 1.99
Structure of a phage 434 Cro/DNA complex. Nature (1988) 1.98
Cleavage of the lambda and P22 repressors by recA protein. J Biol Chem (1982) 1.97
Construction of overproducers of the bacteriophage 434 repressor and cro proteins. J Mol Appl Genet (1981) 1.95
Gene activation by recruitment of the RNA polymerase II holoenzyme. Genes Dev (1996) 1.90