Published in Cell on May 01, 1983
Posttranslational association of immunoglobulin heavy chain binding protein with nascent heavy chains in nonsecreting and secreting hybridomas. J Cell Biol (1986) 8.65
Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme. J Cell Biol (1985) 4.24
Mutations of the Rous sarcoma virus env gene that affect the transport and subcellular location of the glycoprotein products. J Cell Biol (1984) 3.11
A single amino acid substitution in a hydrophobic domain causes temperature-sensitive cell-surface transport of a mutant viral glycoprotein. J Virol (1985) 2.68
Four secretory proteins synthesized by hepatocytes are transported from endoplasmic reticulum to Golgi complex at different rates. EMBO J (1984) 2.27
Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody. Proc Natl Acad Sci U S A (1993) 2.10
Intracellular transport of membrane glycoproteins: two closely related histocompatibility antigens differ in their rates of transit to the cell surface. J Cell Biol (1985) 1.76
The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA. Nucleic Acids Res (1989) 1.60
Gonadotropin beta subunits determine the rate of assembly and the oligosaccharide processing of hormone dimer in transfected cells. J Cell Biol (1987) 1.46
A vesicular intermediate in the transport of hepatoma secretory proteins from the rough endoplasmic reticulum to the Golgi complex. J Cell Biol (1987) 1.44
The variable domain of nonassembled Ig light chains determines both their half-life and binding to the chaperone BiP. Proc Natl Acad Sci U S A (1998) 1.26
Structural mutation affecting intracellular transport and cell surface expression of murine class II molecules. J Exp Med (1988) 1.26
A single amino acid substitution in the variable region of the light chain specifically blocks immunoglobulin secretion. Proc Natl Acad Sci U S A (1990) 1.21
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Beta 2-microglobulin induces intracellular transport of human class I transplantation antigen heavy chains in Xenopus laevis oocytes. J Cell Biol (1984) 1.07
Mutations that influence the secretory path in animal cells. Biochem J (1983) 0.92
Variants of vaccinia virus hemagglutinin altered in intracellular transport. Mol Cell Biol (1986) 0.89
Different exon-intron organization at the 5' part of a mouse class I gene is used to generate a novel H-2Kd-related mRNA. Proc Natl Acad Sci U S A (1983) 0.87
Comparable outcomes in nonsecretory and secretory multiple myeloma after autologous stem cell transplantation. Biol Blood Marrow Transplant (2008) 0.83
Aggregates, crystals, gels, and amyloids: intracellular and extracellular phenotypes at the crossroads of immunoglobulin physicochemical property and cell physiology. Int J Cell Biol (2013) 0.83
Sequence of a cDNA encoding Basilea kappa light chains (K2 isotype) suggests a possible relationship of protein structure to limited expression. J Exp Med (1984) 0.82
Defective secretion of an immunoglobulin caused by mutations in the heavy chain complementarity determining region 2. J Exp Med (1994) 0.81
Alternative pathways of disulfide bond formation yield secretion-competent, stable and functional immunoglobulins. Mol Immunol (2008) 0.76
Sequences of mouse immunoglobulin light chain genes before and after somatic changes. Cell (1978) 7.53
Evidence for somatic rearrangement of immunoglobulin genes coding for variable and constant regions. Proc Natl Acad Sci U S A (1976) 5.81
Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities. EMBO J (1996) 5.17
Cloning of an immunoglobulin variable region gene from mouse embryo. Proc Natl Acad Sci U S A (1977) 3.21
Analysis of cosmids using linearization by phage lambda terminase. Gene (1985) 2.98
Identification of a second Escherichia coli groE gene whose product is necessary for bacteriophage morphogenesis. Proc Natl Acad Sci U S A (1981) 2.94
Head morphogenesis of complex double-stranded deoxyribonucleic acid bacteriophages. Microbiol Rev (1978) 2.82
Intracisternal A-particle genes as movable elements in the mouse genome. Proc Natl Acad Sci U S A (1983) 2.76
Somatic changes in the content and context of immunoglobulin genes. Cold Spring Harb Symp Quant Biol (1977) 2.73
Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat Immunol (2000) 2.59
Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences. Proc Natl Acad Sci U S A (1982) 2.44
Production of functional chimaeric mouse/human antibody. Nature (1985) 2.35
The morphogenesis of bacteriophage lambda. IV. Identification of gene products and control of the expression of the morphogenetic information. Virology (1972) 2.15
Functional immunoglobulin M production after transfection of cloned immunoglobulin heavy and light chain genes into lymphoid cells. Proc Natl Acad Sci U S A (1983) 2.03
Orientation of cohesive end site cos determines the active orientation of chi sequence in stimulating recA . recBC-mediated recombination in phage lambda lytic infections. Proc Natl Acad Sci U S A (1982) 1.90
Studies on an in vitro system for the packaging and maturation of phage lambda DNA. Virology (1977) 1.86
Structural transitions during maturation of bacteriophage lambda capsids. J Mol Biol (1993) 1.79
VH gene family utilization in colonies derived from B and pre-B cells detected by the RNA colony blot assay. EMBO J (1986) 1.77
Bacteriophage lambda DNA: the beginning of the end. J Bacteriol (1990) 1.58
Conservation of sequence in recombination signal sequence spacers. Nucleic Acids Res (1994) 1.58
The role of gene Nu3 in bacteriophage lambda head morphogenesis. Virology (1975) 1.56
Transposition of two different intracisternal A particle elements into an immunoglobulin kappa-chain gene. Mol Cell Biol (1984) 1.55
RNA splicing mutation in an aberrantly rearranged immunoglobulin lambda I gene. Proc Natl Acad Sci U S A (1981) 1.55
Bacteriophage lambda preconnectors. Purification and structure. J Mol Biol (1984) 1.53
Transfer of a cloned immunoglobulin light-chain gene to mutant hybridoma cells restores specific antibody production. Nature (1983) 1.51
The interaction of E. coli integration host factor and lambda cos DNA: multiple complex formation and protein-induced bending. Nucleic Acids Res (1989) 1.50
Morphogenetic genes C and Nu3 overlap in bacteriophage lambda. Nature (1980) 1.49
Hypothesis: genes which function in a stochastic lineage commitment process are subject to monoallelic expression. Semin Immunol (1999) 1.42
Molecular cloning of an immunoglobulin kappa constant gene from NZB mouse. Gene (1981) 1.37
Enumeration and characterization of DJH structures in mouse fetal liver. EMBO J (1992) 1.37
The morphogenesis of bacteriophage lambda. II. Identification of the principal structural proteins. Virology (1970) 1.36
Stimulation of groE synthesis in Escherichia coli by bacteriophage lambda infection. J Bacteriol (1982) 1.36
Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain. Proc Natl Acad Sci U S A (1991) 1.36
Site-specific DNA methylation by a complex of PU.1 and Dnmt3a/b. Oncogene (2006) 1.35
Functional differences between immunoglobulins M and D expressed on the surface of an immature B-cell line. Proc Natl Acad Sci U S A (1988) 1.33
High level functional engraftment of severe combined immunodeficient mice with human peripheral blood lymphocytes following pretreatment with radiation and anti-asialo GM1. J Immunol Methods (1994) 1.32
Modulation of the IL-7 dose-response threshold during pro-B cell differentiation is dependent on pre-B cell receptor expression. J Immunol (1998) 1.31
Genetic map of bacteriophage lambda. Microbiol Rev (1978) 1.25
Early intermediates in bacteriophage lambda prohead assembly. II. Identification of biologically active intermediates. Virology (1983) 1.23
Rearrangement of the T-cell receptor beta-chain gene in non-T-cell, non-B-cell acute lymphoblastic leukemia of childhood. N Engl J Med (1985) 1.23
Dynamics of immunoglobulin genes. Immunol Rev (1977) 1.22
Early intermediates in bacteriophage lambda prohead assembly. Virology (1979) 1.21
Killing of antigen-reactive B cells by class II-restricted, soluble antigen-specific CD8+ cytolytic T lymphocytes. Nature (1988) 1.18
Nucleotide sequence of a chromosomal rearranged lambda 2 immunoglobulin gene of mouse. Nucleic Acids Res (1982) 1.17
B and T cells are not required for the viable motheaten phenotype. J Exp Med (1996) 1.14
Human primary immune response in SCID mice engrafted with human peripheral blood lymphocytes. J Immunol (1994) 1.13
Frequency of VH81x usage during B cell development: initial decline in usage is independent of Ig heavy chain cell surface expression. J Immunol (1996) 1.13
Inducible cellular transformation by a metallothionein-ras hybrid oncogene leads to natural killer cell susceptibility. Nature (1986) 1.11
Immunoglobulin mu-chain gene rearrangement in a patient with T cell acute lymphoblastic leukemia. J Clin Invest (1984) 1.10
Molecular cloning of POEM: a novel adhesion molecule that interacts with alpha8beta1 integrin. J Biol Chem (2001) 1.10
Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector. Proc Natl Acad Sci U S A (1985) 1.09
Immunoglobulin gene rearrangement in acute myelogenous leukemia. Cancer Res (1984) 1.08
Kappa light chain rearrangement in mouse fetal liver. J Immunol (1994) 1.07
Analysis of hybridoma mutants defective in synthesis of immunoglobulin M. Somat Cell Mol Genet (1986) 1.06
The overproduction of DNA terminase of coliphage lambda. Gene (1987) 1.06
High frequency of normal DJH joints in B cell progenitors in severe combined immunodeficiency mice. J Exp Med (1993) 1.04
Poly(U) polymerase in rat brain. Nature (1975) 1.04
A linkage map of the mouse immunoglobulin lambda light chain locus. Immunogenetics (1989) 1.04
The morphogenesis of phage lambda. V. Form-determining function of the genes required for the assembly of the head. Virology (1972) 1.04
Nucleotide sequences of immunoglobulin mu heavy chain deletion mutants. Nucleic Acids Res (1983) 1.03
Antigen presentation by a B-cell line transfected with cloned immunoglobulin heavy- and light-chain genes specific for a defined hapten. Proc Natl Acad Sci U S A (1986) 1.02
The origins of V(D)J recombination. Cell (1997) 1.00
Development of CD4+CD8+ thymocytes in RAG-deficient mice through a T cell receptor beta chain-independent pathway. J Exp Med (1995) 1.00
The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1. Curr Biol (1998) 0.99
Characterization of a mouse DNA clone containing an immunoglobulin variable region gene. Nucleic Acids Res (1978) 0.99
Development of the immunoglobulin repertoire. Clin Immunol Immunopathol (1996) 0.98
Somatic point mutations in unrearranged immunoglobulin gene segments encoding the variable region of lambda light chains. EMBO J (1987) 0.98
The old and the restless. J Exp Med (2000) 0.97
Rejection of B16 melanoma induced by expression of a transfected major histocompatibility complex class I gene. Mol Cell Biol (1988) 0.97
Bacteriophage lambda DNA maturation. The functional relationships among the products of genes Nul, A and FI. J Mol Biol (1981) 0.96
Tolerance is overcome in beef insulin-transgenic mice by activation of low-affinity autoreactive T cells. Eur J Immunol (1996) 0.95
Amplification of the gene for histidyl-tRNA synthetase in histidinol-resistant Chinese hamster ovary cells. Mol Cell Biol (1985) 0.95
Activation of complement by immunoglobulin M is impaired by the substitution serine-406----asparagine in the immunoglobulin mu heavy chain. Proc Natl Acad Sci U S A (1986) 0.95
Amino acid residues in the T cell receptor CDR3 determine the antigenic reactivity patterns of insulin-reactive hybridomas. J Immunol (1991) 0.95
Class I (H-2Kb) gene transfection reduces susceptibility of YAC-1 lymphoma targets to natural killer cells. Eur J Immunol (1990) 0.94
The maturation of coliphage lambda DNA in the absence of its packaging. Gene (1984) 0.93
Endogenous interleukin 6 can function as an in vivo growth- stimulatory factor for advanced-stage human melanoma cells. Clin Cancer Res (1996) 0.93
Complement activation by IgM: evidence for the importance of the third constant domain of the mu heavy chain. Eur J Immunol (1987) 0.92
Detection of RNA transcripts in normal lymphoid and myeloid colonies. J Immunol Methods (1986) 0.92
Production of lambda-phi 29 phage chimeras. Virology (1990) 0.92
Bacteriophage lambda DNA packaging. The product of the FI gene promotes the incorporation of the prohead to the DNA-terminase complex. J Mol Biol (1988) 0.92
Synthesis of a trans-acting inhibitor of DNA maturation by prohead mutants of phage lambda. Genetics (1987) 0.91
A human model of xenogeneic graft-versus-host disease in SCID mice engrafted with human peripheral blood lymphocytes. Transplantation (1995) 0.91
Ig gene rearrangements on individual alleles of Abelson murine leukemia cell lines from (C57BL/6 x BALB/c) F1 fetal livers. J Immunol (1991) 0.91
V(H) gene replacement occurs in the spleen and bone marrow of non-autoimmune quasi-monoclonal mice. Eur J Immunol (1998) 0.90
Differential sensitivity of specific and nonspecific antigen-presentation by B cells to a protein synthesis inhibitor. J Immunol (1990) 0.89
Lineage specific classification of leukaemia: results of the analysis of sixty cases of childhood leukaemia. Br J Haematol (1985) 0.89
Somatic generation of antibody diversity. Ann Immunol (Paris) (1976) 0.89
Identification of USF as the ubiquitous murine factor that binds to and stimulates transcription from the immunoglobulin lambda 2-chain promoter. Nucleic Acids Res (1992) 0.89
A genetic analysis of bacteriophage lambda prohead assembly in vitro. J Mol Biol (1978) 0.89
Inversions produced during V(D)J rearrangement at IgH, the immunoglobulin heavy-chain locus. Mol Cell Biol (1995) 0.89
Molecular mechanisms involved in receptor editing at the Ig heavy chain locus. Int Immunol (1998) 0.89