Published in J Cell Biol on October 01, 1980
The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy. J Cell Biol (1986) 3.90
Structure of nuclear ribonucleoprotein: identification of proteins in contact with poly(A)+ heterogeneous nuclear RNA in living HeLa cells. J Cell Biol (1981) 2.42
Structure of nuclear ribonucleoprotein: heterogeneous nuclear RNA is complexed with a major sextet of proteins in vivo. Proc Natl Acad Sci U S A (1983) 2.19
Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly. J Cell Biol (1984) 1.81
Nuclear ribonucleoprotein particles probed in living cells. Proc Natl Acad Sci U S A (1981) 1.79
Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs. Nucleic Acids Res (1990) 1.68
Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells. Mol Cell Biol (1983) 1.54
Nuclear RNA-protein interactions and messenger RNA processing. J Cell Biol (1983) 1.33
Abundant nuclear ribonucleoprotein form of CAD RNA. Mol Cell Biol (1985) 1.30
Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA. Proc Natl Acad Sci U S A (1993) 1.28
Nuclear matrix and hnRNP share a common structural constituent associated with premessenger RNA. EMBO J (1983) 1.19
In vitro assembly of a pre-messenger ribonucleoprotein. Proc Natl Acad Sci U S A (1983) 1.09
Identification of proteins that bind tightly to pre-mRNA during in vitro splicing. Proc Natl Acad Sci U S A (1986) 1.03
Sequence dependent interaction of hnRNP proteins with late adenoviral transcripts. Nucleic Acids Res (1982) 1.02
U1, U2, and U6 small nuclear ribonucleoproteins (snRNPs) are associated with large nuclear RNP particles containing transcripts of an amplified gene in vivo. Proc Natl Acad Sci U S A (1986) 1.00
A major heat-shock protein defined by a monoclonal antibody. EMBO J (1984) 0.97
Ultrastructure of free ribonucleoprotein complexes in spread mammalian nuclei. J Cell Biol (1982) 0.96
Localization of heterogeneous nuclear ribonucleoprotein in the interphase nuclear matrix core filaments and on perichromosomal filaments at mitosis. Proc Natl Acad Sci U S A (1991) 0.90
Assembly of nuclear ribonucleoprotein particles during in vitro transcription. Proc Natl Acad Sci U S A (1982) 0.88
A unique ribonucleoprotein complex assembles preferentially on ecdysone-responsive sites in Drosophila melanogaster. Mol Cell Biol (1993) 0.87
Specific regions of beta-globin RNA are resistant to nuclease digestion in RNA-protein complexes in chicken reticulocyte nuclei. Mol Cell Biol (1985) 0.80
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J Mol Biol (1977) 205.11
Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paper. Methods Enzymol (1979) 18.24
A freeze-squeeze method for recovering long DNA from agarose gels. Anal Biochem (1975) 11.28
THE CELLULAR SITES OF SYNTHESIS OF RIBOSOMAL AND 4S RNA. Proc Natl Acad Sci U S A (1962) 6.61
The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor. Proc Natl Acad Sci U S A (1978) 6.20
Identification and characterization of the packaging proteins of core 40S hnRNP particles. Cell (1977) 5.50
Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences. Proc Natl Acad Sci U S A (1977) 5.28
Fine structural organization of the interphase nucleus in some mammalian cells. J Ultrastruct Res (1969) 3.81
RNA transport from nucleus to cytoplasm in Chironomus salivary glands. J Cell Biol (1966) 3.41
Globin RNA precursor molecules: biosynthesis and process in erythroid cells. Cell (1977) 3.40
Structural organization of nuclear complexes containing DNA-like RNA. J Mol Biol (1968) 3.38
Proteins associated with heterogeneous nuclear RNA in eukaryotic cells. J Mol Biol (1974) 3.13
Characterization of the non-histone nuclear proteins associated with rapidly labeled heterogeneous nuclear RNA. J Biol Chem (1977) 2.84
Precursors of alpha and beta globin messenger RNAs. J Mol Biol (1978) 2.26
The precursor of mouse beta-globin messenger RNA contains two intervening RNA sequences. Cell (1978) 2.21
Some properties of RNA:protein complexes from the nucleus of eukaryotic cells. Cold Spring Harb Symp Quant Biol (1974) 2.11
Comparison of proteins bound to heterogeneous nuclear RNA and messenger RNA in HeLa cells. J Mol Biol (1975) 2.00
Interaction of HeLa cell proteins with RNA. J Mol Biol (1970) 1.90
Sequence organization of the beta-globin mRNA precursor. Nucleic Acids Res (1978) 1.89
Poly (A)-rich ribonucleoprotein complexes from HeLa cell messenger RNA. J Biol Chem (1976) 1.74
The effect of HeLa cell cytoplasm on the rate of sedimentation of RNA. Proc Natl Acad Sci U S A (1966) 1.69
Ribonucleoprotein organization of polyadenylate sequences in HeLa cell heterogeneous nuclear RNA. J Mol Biol (1975) 1.67
Post-replicative nonribosomal transcription units in D. melanogaster embryos. Cell (1979) 1.64
Characterization of ribosomal precursor particles from HeLa cell nucleoli. J Mol Biol (1972) 1.61
Chromatin: its isolation from cultured mammalian cells with particular reference to contamination by nuclear ribnucleoprotein particles. Biochemistry (1973) 1.54
Evolution of the transcription unit of ribosomal RNA. Proc Natl Acad Sci U S A (1970) 1.49
Analysis of chromatin-associated fiber arrays. Chromosoma (1976) 1.45
Nonhistone chromosomal proteins in synchronized HeLa cells. Proc Natl Acad Sci U S A (1972) 1.32
Secondary structure of heterogeneous nuclear RNA: two classes of double-stranded RNA in native ribonucleoprotein. Proc Natl Acad Sci U S A (1977) 1.31
The structure of chromosome-derived ribonucleoprotein in oocytes of Triturus cristatus carnifex (Laurenti). Chromosoma (1974) 1.30
Morphology of transcription units in Drosophila melanogaster. Chromosoma (1976) 1.26
Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1975) 1.25
STUDIES ON ISOLATED NUCLEI. II. ISOLATION AND CHEMICAL CHARACTERIZATION OF NUCLEOLAR AND NUCLEOPLASMIC SUBFRACTIONS. J Cell Biol (1963) 1.24
Gene activation in eukaryotes: are nuclear acidic proteins the cause or the effect? Proc Natl Acad Sci U S A (1974) 1.20
Isolation and characterization of ribonucleoprotein particles containing heterogeneous nuclear RNA. Methods Cell Biol (1978) 1.17
Nucleoprotein organization of inverted repeat DNA transcripts in heterogeneous nuclear RNA-ribonucleoprotein particles from HeLa cells. J Mol Biol (1978) 1.15
Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A (1979) 1.15
Evidence for a role of RNA in eukaryotic chromosome structure. Metabolically stable, small nuclear RNA species are covalently linked to chromosomal DNA in HeLa cells. J Mol Biol (1979) 1.07
Relationship between protein synthesis and ribosome assembly in HeLa cells. J Mol Biol (1971) 1.06
Centrifugation of nuclear ribonucleoprotein particles of sea urchin embryos in cesium sulfate. Biochemistry (1973) 0.96
Isolation and characterization of chromatin from the cellular slime mold, Dictyostelium discoideum. Biochemistry (1977) 0.95
A quantitative electron microscopic analysis of transcription in sea urchin embryos. Chromosoma (1979) 0.93
Heterogeneous nuclear RNA secondary structure: oligo (U) sequences base-paired with poly (A) and their possible role as binding sites for heterogeneous nuclear RNA-specific proteins. Proc Natl Acad Sci U S A (1977) 0.91
Photochemical cross-linking of secondary structure in HeLa cell heterogeneous nuclear RNA in situ 1. Nucleic Acids Res (1979) 0.88
Chromatin structure and gene transcription: nucleosomes permit a new synthesis. Int Rev Cytol (1978) 0.87
Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells. Proc Natl Acad Sci U S A (1998) 3.36
U6 small nuclear RNA is transcribed by RNA polymerase III. Proc Natl Acad Sci U S A (1986) 3.14
Proteins associated with heterogeneous nuclear RNA in eukaryotic cells. J Mol Biol (1974) 3.13
An artificial anchor domain: hydrophobicity suffices to stop transfer. Cell (1985) 2.65
Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used. Genes Dev (1988) 2.55
Base-pairing interactions between small nuclear RNAs and nuclear RNA precursors as revealed by psoralen cross-linking in vivo. Cell (1981) 2.49
Structure of nuclear ribonucleoprotein: identification of proteins in contact with poly(A)+ heterogeneous nuclear RNA in living HeLa cells. J Cell Biol (1981) 2.42
Fine structure of a membrane anchor domain. J Mol Biol (1985) 2.40
Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells. Curr Biol (1999) 2.20
Structure of nuclear ribonucleoprotein: heterogeneous nuclear RNA is complexed with a major sextet of proteins in vivo. Proc Natl Acad Sci U S A (1983) 2.19
Clathrin facilitates the internalization of seven transmembrane segment receptors for mating pheromones in yeast. J Cell Biol (1993) 2.14
Ubiquitination of the yeast a-factor receptor. J Cell Biol (1996) 2.06
Comparison of proteins bound to heterogeneous nuclear RNA and messenger RNA in HeLa cells. J Mol Biol (1975) 2.00
Nuclear domains of the RNA subunit of RNase P. J Cell Sci (1997) 1.99
The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins. Proc Natl Acad Sci U S A (1988) 1.98
Signal recognition particle components in the nucleolus. Proc Natl Acad Sci U S A (2000) 1.95
Regulated transcription of the genes for actin and heat-shock proteins in cultured Drosophila cells. J Cell Biol (1981) 1.95
Reconstitution of the U1 small nuclear ribonucleoprotein particle. Mol Cell Biol (1987) 1.94
Chromatin structure and the cell cycle. Proc Natl Acad Sci U S A (1972) 1.91
Localization of signal recognition particle RNA in the nucleolus of mammalian cells. Proc Natl Acad Sci U S A (1998) 1.89
Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly. J Cell Biol (1984) 1.81
Nuclear ribonucleoprotein particles probed in living cells. Proc Natl Acad Sci U S A (1981) 1.79
Dynamic localization of RNase MRP RNA in the nucleolus observed by fluorescent RNA cytochemistry in living cells. J Cell Biol (1995) 1.77
Localization of pre-messenger RNA at discrete nuclear sites. Proc Natl Acad Sci U S A (1991) 1.74
Poly (A)-rich ribonucleoprotein complexes from HeLa cell messenger RNA. J Biol Chem (1976) 1.74
Small nuclear ribonucleoproteins of Drosophila: identification of U1 RNA-associated proteins and their behavior during heat shock. Mol Cell Biol (1982) 1.70
Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs. Nucleic Acids Res (1990) 1.68
Ribonucleoprotein organization of polyadenylate sequences in HeLa cell heterogeneous nuclear RNA. J Mol Biol (1975) 1.67
Transcription-dependent localization of U1 and U2 small nuclear ribonucleoproteins at major sites of gene activity in polytene chromosomes. J Mol Biol (1984) 1.66
Protein binding sites are conserved in U1 small nuclear RNA from insects and mammals. Proc Natl Acad Sci U S A (1983) 1.63
cDNA cloning of a human autoimmune nuclear ribonucleoprotein antigen. Proc Natl Acad Sci U S A (1985) 1.59
U1 small nuclear ribonucleoprotein particle-specific proteins interact with the first and second stem-loops of U1 RNA, with the A protein binding directly to the RNA independently of the 70K and Sm proteins. Mol Cell Biol (1989) 1.56
Chromatin: its isolation from cultured mammalian cells with particular reference to contamination by nuclear ribnucleoprotein particles. Biochemistry (1973) 1.54
Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells. Mol Cell Biol (1983) 1.54
Small nuclear RNA U2 is base-paired to heterogeneous nuclear RNA. Science (1982) 1.53
Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proc Natl Acad Sci U S A (1990) 1.50
Eukaryotic small ribonucleoproteins. Anti-La human autoantibodies react with U1 RNA-protein complexes. J Biol Chem (1984) 1.46
Akr1p and the type I casein kinases act prior to the ubiquitination step of yeast endocytosis: Akr1p is required for kinase localization to the plasma membrane. Mol Cell Biol (2000) 1.41
Comparison of mitotic phenomena and effects induced by hypertonic solutions in HeLa cells. J Cell Biol (1970) 1.37
Precursors of U4 small nuclear RNA. J Cell Biol (1984) 1.36
Transcription of a human U6 small nuclear RNA gene in vivo withstands deletion of intragenic sequences but not of an upstream TATATA box. Nucleic Acids Res (1989) 1.36
Transcription boundaries of U1 small nuclear RNA. Mol Cell Biol (1985) 1.36
Review: movement of mRNA from transcription site to nuclear pores. J Struct Biol (2000) 1.35
Nuclear RNA-protein interactions and messenger RNA processing. J Cell Biol (1983) 1.33
Nonhistone chromosomal proteins in synchronized HeLa cells. Proc Natl Acad Sci U S A (1972) 1.32
Secondary structure of heterogeneous nuclear RNA: two classes of double-stranded RNA in native ribonucleoprotein. Proc Natl Acad Sci U S A (1977) 1.31
The small nuclear RNAs of Drosophila. J Mol Biol (1984) 1.30
A large PEST-like sequence directs the ubiquitination, endocytosis, and vacuolar degradation of the yeast a-factor receptor. J Cell Biol (1998) 1.29
Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA. Proc Natl Acad Sci U S A (1993) 1.28
Diffusional protein transport within the nucleus: a message in the medium. Nat Cell Biol (2000) 1.26
Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1975) 1.25
Pseudouridine formation in U2 small nuclear RNA. Proc Natl Acad Sci U S A (1994) 1.24
Ubiquitination of the PEST-like endocytosis signal of the yeast a-factor receptor. J Biol Chem (2000) 1.24
Iron: its intracellular localization and possible role in cell division. Proc Natl Acad Sci U S A (1970) 1.20
Gene activation in eukaryotes: are nuclear acidic proteins the cause or the effect? Proc Natl Acad Sci U S A (1974) 1.20
Recycling of the yeast a-factor receptor. J Cell Biol (2000) 1.19
Response of yeast alpha cells to a-factor pheromone: topology of the receptor and identification of a component of the response pathway. Cold Spring Harb Symp Quant Biol (1988) 1.18
U2 small nuclear RNP assembly in vitro. Nucleic Acids Res (1989) 1.18
Isolation and characterization of ribonucleoprotein particles containing heterogeneous nuclear RNA. Methods Cell Biol (1978) 1.17
U1 small nuclear ribonucleoprotein studied by in vitro assembly. J Cell Biol (1983) 1.16
Ribonucleoprotein organization of eukaryotic RNA. XXXII. U2 small nuclear RNA precursors and their accurate 3' processing in vitro as ribonucleoprotein particles. J Mol Biol (1985) 1.15
Nucleoprotein organization of inverted repeat DNA transcripts in heterogeneous nuclear RNA-ribonucleoprotein particles from HeLa cells. J Mol Biol (1978) 1.15
Sequence complexity of nuclear and messenger RNA in HeLa cells. J Mol Biol (1980) 1.15
Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A (1979) 1.15
Mutations that alter the third cytoplasmic loop of the a-factor receptor lead to a constitutive and hypersensitive phenotype. Proc Natl Acad Sci U S A (1993) 1.14
Chromatin structure and the cell division cycle. Actinomycin binding in synchronized HeLa cells. J Cell Biol (1972) 1.11
A 62,000 molecular weight spliceosome protein crosslinks to the intron polypyrimidine tract. Nucleic Acids Res (1990) 1.10
Accurate and efficient 3' processing of U2 small nuclear RNA precursor in a fractionated cytoplasmic extract. Mol Cell Biol (1987) 1.10
In vitro assembly of a pre-messenger ribonucleoprotein. Proc Natl Acad Sci U S A (1983) 1.09
Evidence for a role of RNA in eukaryotic chromosome structure. Metabolically stable, small nuclear RNA species are covalently linked to chromosomal DNA in HeLa cells. J Mol Biol (1979) 1.07
A special class of non-histone protein tightly complexed with template-inactive DNA in chromatin. Biochemistry (1975) 1.07
Relationship between protein synthesis and ribosome assembly in HeLa cells. J Mol Biol (1971) 1.06
A 7-methylguanosine cap commits U3 and U8 small nuclear RNAs to the nucleolar localization pathway. Nucleic Acids Res (1998) 1.05
U2 small nuclear RNA 3' end formation is directed by a critical internal structure distinct from the processing site. Mol Cell Biol (1993) 1.04
Identification of proteins that bind tightly to pre-mRNA during in vitro splicing. Proc Natl Acad Sci U S A (1986) 1.03
RNA processing and ribonucleoprotein assembly studied in vivo by RNA transfection. Proc Natl Acad Sci U S A (1990) 1.03
Ribonucleoprotein organization of eukaryotic RNA. XXXI. Structure of the U1 small nuclear ribonucleoprotein. J Mol Biol (1984) 0.99
Ribonucleoprotein organization of eukaryotic RNA. XXX. Evidence that U1 small nuclear RNA is a ribonucleoprotein when base-paired with pre-messenger RNA in vivo. J Mol Biol (1984) 0.99
A human U2 RNA mutant stalled in 3' end processing is impaired in nuclear import. Nucleic Acids Res (1999) 0.95
Isolation and characterization of chromatin from the cellular slime mold, Dictyostelium discoideum. Biochemistry (1977) 0.95
A method for improving synchrony in the G2 phase of the cell cycle. J Cell Biol (1971) 0.94
A beta-like DNA polymerase activity in the slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1980) 0.94
Ribonucleoprotein organization of eukaryotic RNA. XV. Different nucleoprotein structures of globin messenger RNA sequences in nuclear and polyribosomal ribonucleoprotein particles. J Mol Biol (1981) 0.94
Messenger RNA biosynthesis and nuclear structure. Am Sci (1981) 0.93
Messenger RNA sequences in nuclear ribonucleoprotein particles are complexed with protein as shown by nuclease protection. J Mol Biol (1981) 0.92
Direct characterization of influenza viral NS1 mRNA and related sequences from infected HeLa cells and a cell-free transcription system. Biochim Biophys Acta (1986) 0.92
Heterogeneous nuclear RNA secondary structure: oligo (U) sequences base-paired with poly (A) and their possible role as binding sites for heterogeneous nuclear RNA-specific proteins. Proc Natl Acad Sci U S A (1977) 0.91
Feedback phosphorylation of the yeast a-factor receptor requires activation of the downstream signaling pathway from G protein through mitogen-activated protein kinase. Mol Cell Biol (2000) 0.91
3' processing of human pre-U2 small nuclear RNA: a base-pairing interaction between the 3' extension of the precursor and an internal region. Mol Cell Biol (1997) 0.90
Assembly of nuclear ribonucleoprotein particles during in vitro transcription. Proc Natl Acad Sci U S A (1982) 0.88
G2-population cells in mouse kidney and duodenum and their behavior during the cell division cycle. Exp Cell Res (1970) 0.88
Photochemical cross-linking of secondary structure in HeLa cell heterogeneous nuclear RNA in situ 1. Nucleic Acids Res (1979) 0.88
A hybrid toxin from bacteriophage f1 attachment protein and colicin E3 has altered cell receptor specificity. J Bacteriol (1988) 0.87
Chromatin structure and gene transcription: nucleosomes permit a new synthesis. Int Rev Cytol (1978) 0.87
The U2 small nuclear ribonucleoprotein particle associates with nuclear factors in a pre-mRNA independent reaction. J Biol Chem (1991) 0.87
Asg7p-Ste3p inhibition of pheromone signaling: regulation of the zygotic transition to vegetative growth. Mol Cell Biol (2000) 0.87
A discrete 3' region of U6 small nuclear RNA modulates the phosphorylation cycle of the C1 heterogeneous nuclear ribonucleoprotein particle protein. Mol Cell Biol (1996) 0.86
Cassettes of the f1 intergenic region. Nucleic Acids Res (1989) 0.86
RNA synthesis in HeLa cells. Pattern in hypertonic medium and its similarity to synthesis during G2-prophase. J Cell Biol (1970) 0.86
RNA-dependent phosphorylation of a nuclear RNA binding protein. Proc Natl Acad Sci U S A (1997) 0.85