Published in Mol Cell Biol on February 01, 1993
Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Yeast (2000) 3.85
Modified nucleotides at the 5' end of human U2 snRNA are required for spliceosomal E-complex formation. RNA (2004) 1.63
Interactions of U2 gene loci and their nuclear transcripts with Cajal (coiled) bodies: evidence for PreU2 within Cajal bodies. Mol Biol Cell (2000) 1.27
Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis. Mol Cell (2010) 1.27
Pseudouridine formation in U2 small nuclear RNA. Proc Natl Acad Sci U S A (1994) 1.24
Determinants for cap trimethylation of the U2 small nuclear RNA are not conserved between Trypanosoma brucei and higher eukaryotic organisms. Nucleic Acids Res (2000) 1.12
3'-box-dependent processing of human pre-U1 snRNA requires a combination of RNA and protein co-factors. Nucleic Acids Res (2004) 0.93
3' processing of human pre-U2 small nuclear RNA: a base-pairing interaction between the 3' extension of the precursor and an internal region. Mol Cell Biol (1997) 0.90
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Res (1984) 86.56
Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci U S A (1985) 68.48
RNA metabolism in the HeLa cell nucleus. J Mol Biol (1966) 17.11
Are snRNPs involved in splicing? Nature (1980) 15.47
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1979) 14.61
Spliceosomal snRNAs. Annu Rev Genet (1988) 8.09
The biochemistry of 3'-end cleavage and polyadenylation of messenger RNA precursors. Annu Rev Biochem (1992) 4.20
Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing. Genes Dev (1989) 3.95
A compensatory base change in human U2 snRNA can suppress a branch site mutation. Genes Dev (1989) 3.79
Formation of the 3' end of U1 snRNA requires compatible snRNA promoter elements. Cell (1986) 3.69
3' end formation of U1 snRNA precursors is coupled to transcription from snRNA promoters. Cell (1986) 3.61
Intracellular transport of microinjected 5S and small nuclear RNAs. Nature (1982) 3.28
The trimethylguanosine cap structure of U1 snRNA is a component of a bipartite nuclear targeting signal. Cell (1990) 3.24
U6 small nuclear RNA is transcribed by RNA polymerase III. Proc Natl Acad Sci U S A (1986) 3.14
An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus. Science (1990) 2.98
Formation of the 3' end of U1 snRNA is directed by a conserved sequence located downstream of the coding region. EMBO J (1985) 2.69
Sequences required for 3' end formation of human U2 small nuclear RNA. Cell (1985) 2.57
Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used. Genes Dev (1988) 2.55
Human genes for U2 small nuclear RNA are tandemly repeated. Mol Cell Biol (1984) 2.52
Base-pairing interactions between small nuclear RNAs and nuclear RNA precursors as revealed by psoralen cross-linking in vivo. Cell (1981) 2.49
The capped U6 small nuclear RNA is transcribed by RNA polymerase III. J Biol Chem (1987) 2.39
Intron splicing: a conserved internal signal in introns of Drosophila pre-mRNAs. Nucleic Acids Res (1985) 2.35
Recognition of U1 and U2 small nuclear RNAs can be altered by a 5-amino-acid segment in the U2 small nuclear ribonucleoprotein particle (snRNP) B" protein and through interactions with U2 snRNP-A' protein. Mol Cell Biol (1991) 2.33
Histone 3' ends: essential and regulatory functions. Gene Expr (1992) 2.31
Lethal and temperature-sensitive mutations and their suppressors identify an essential structural element in U2 small nuclear RNA. Genes Dev (1990) 2.31
Base pairing between U2 and U6 snRNAs is necessary for splicing of a mammalian pre-mRNA. Nature (1991) 2.30
Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles. Genes Dev (1990) 2.26
Genetic evidence for base pairing between U2 and U6 snRNA in mammalian mRNA splicing. Nature (1991) 2.24
Functional analysis of mutant Xenopus U2 snRNAs. Cell (1989) 2.23
Human U2 and U1 RNA genes use similar transcription signals. EMBO J (1984) 2.01
U3 small nuclear RNA can be psoralen-cross-linked in vivo to the 5' external transcribed spacer of pre-ribosomal-RNA. Proc Natl Acad Sci U S A (1989) 2.00
The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins. Proc Natl Acad Sci U S A (1988) 1.98
Nucleocytoplasmic transport and processing of small nuclear RNA precursors. Mol Cell Biol (1990) 1.96
Chromatin structure and the cell cycle. Proc Natl Acad Sci U S A (1972) 1.91
Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly. J Cell Biol (1984) 1.81
Cyclic 2',3'-phosphates and nontemplated nucleotides at the 3' end of spliceosomal U6 small nuclear RNA's. Science (1992) 1.74
In vitro reconstitution of functional yeast U2 snRNPs. Genes Dev (1989) 1.66
Two conserved domains of yeast U2 snRNA are separated by 945 nonessential nucleotides. Cell (1988) 1.64
Protein binding sites are conserved in U1 small nuclear RNA from insects and mammals. Proc Natl Acad Sci U S A (1983) 1.63
Clustered genes for human U2 RNA. Proc Natl Acad Sci U S A (1984) 1.59
Small nuclear RNA U2 is base-paired to heterogeneous nuclear RNA. Science (1982) 1.53
Small RNAs in the nucleus and cytoplasm of HeLa cells. Biochem Biophys Res Commun (1976) 1.50
Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding. J Virol (1990) 1.48
Molecular cloning and characterization of a gene for rat U2 small nuclear RNA. J Mol Biol (1983) 1.47
Eukaryotic small ribonucleoproteins. Anti-La human autoantibodies react with U1 RNA-protein complexes. J Biol Chem (1984) 1.46
Efficient association of U2 snRNPs with pre-mRNA requires an essential U2 RNA structural element. Genes Dev (1991) 1.45
Precursors of U4 small nuclear RNA. J Cell Biol (1984) 1.36
Transcription boundaries of U1 small nuclear RNA. Mol Cell Biol (1985) 1.36
Short-lived, small RNAs in the cytoplasm of HeLa cells. Cell (1974) 1.35
Internal sequences that distinguish yeast from metazoan U2 snRNA are unnecessary for pre-mRNA splicing. Nature (1988) 1.34
Nuclear processing of the 3'-terminal nucleotides of pre-U1 RNA in Xenopus laevis oocytes. Mol Cell Biol (1992) 1.22
A weak interaction between the U2A' protein and U2 snRNA helps to stabilize their complex with the U2B" protein. Nucleic Acids Res (1991) 1.21
U2 small nuclear RNP assembly in vitro. Nucleic Acids Res (1989) 1.18
Ribonucleoprotein organization of eukaryotic RNA. XXXII. U2 small nuclear RNA precursors and their accurate 3' processing in vitro as ribonucleoprotein particles. J Mol Biol (1985) 1.15
Accurate and efficient 3' processing of U2 small nuclear RNA precursor in a fractionated cytoplasmic extract. Mol Cell Biol (1987) 1.10
RNA processing and ribonucleoprotein assembly studied in vivo by RNA transfection. Proc Natl Acad Sci U S A (1990) 1.03
Solid-phase processing of U2 snRNA precursors. Biochemistry (1986) 0.82
Drosophila 5 S RNA processing requires the 1-118 base pair and additional sequence proximal to the processing site. J Biol Chem (1991) 0.78
Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells. Proc Natl Acad Sci U S A (1998) 3.36
U6 small nuclear RNA is transcribed by RNA polymerase III. Proc Natl Acad Sci U S A (1986) 3.14
Proteins associated with heterogeneous nuclear RNA in eukaryotic cells. J Mol Biol (1974) 3.13
Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used. Genes Dev (1988) 2.55
Base-pairing interactions between small nuclear RNAs and nuclear RNA precursors as revealed by psoralen cross-linking in vivo. Cell (1981) 2.49
Structure of nuclear ribonucleoprotein: identification of proteins in contact with poly(A)+ heterogeneous nuclear RNA in living HeLa cells. J Cell Biol (1981) 2.42
Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells. Curr Biol (1999) 2.20
Structure of nuclear ribonucleoprotein: heterogeneous nuclear RNA is complexed with a major sextet of proteins in vivo. Proc Natl Acad Sci U S A (1983) 2.19
Comparison of proteins bound to heterogeneous nuclear RNA and messenger RNA in HeLa cells. J Mol Biol (1975) 2.00
Nuclear domains of the RNA subunit of RNase P. J Cell Sci (1997) 1.99
The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins. Proc Natl Acad Sci U S A (1988) 1.98
Signal recognition particle components in the nucleolus. Proc Natl Acad Sci U S A (2000) 1.95
Regulated transcription of the genes for actin and heat-shock proteins in cultured Drosophila cells. J Cell Biol (1981) 1.95
Reconstitution of the U1 small nuclear ribonucleoprotein particle. Mol Cell Biol (1987) 1.94
Chromatin structure and the cell cycle. Proc Natl Acad Sci U S A (1972) 1.91
Localization of signal recognition particle RNA in the nucleolus of mammalian cells. Proc Natl Acad Sci U S A (1998) 1.89
Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly. J Cell Biol (1984) 1.81
Nuclear ribonucleoprotein particles probed in living cells. Proc Natl Acad Sci U S A (1981) 1.79
Dynamic localization of RNase MRP RNA in the nucleolus observed by fluorescent RNA cytochemistry in living cells. J Cell Biol (1995) 1.77
Localization of pre-messenger RNA at discrete nuclear sites. Proc Natl Acad Sci U S A (1991) 1.74
Poly (A)-rich ribonucleoprotein complexes from HeLa cell messenger RNA. J Biol Chem (1976) 1.74
Small nuclear ribonucleoproteins of Drosophila: identification of U1 RNA-associated proteins and their behavior during heat shock. Mol Cell Biol (1982) 1.70
Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs. Nucleic Acids Res (1990) 1.68
Ribonucleoprotein organization of polyadenylate sequences in HeLa cell heterogeneous nuclear RNA. J Mol Biol (1975) 1.67
Transcription-dependent localization of U1 and U2 small nuclear ribonucleoproteins at major sites of gene activity in polytene chromosomes. J Mol Biol (1984) 1.66
Protein binding sites are conserved in U1 small nuclear RNA from insects and mammals. Proc Natl Acad Sci U S A (1983) 1.63
cDNA cloning of a human autoimmune nuclear ribonucleoprotein antigen. Proc Natl Acad Sci U S A (1985) 1.59
U1 small nuclear ribonucleoprotein particle-specific proteins interact with the first and second stem-loops of U1 RNA, with the A protein binding directly to the RNA independently of the 70K and Sm proteins. Mol Cell Biol (1989) 1.56
Chromatin: its isolation from cultured mammalian cells with particular reference to contamination by nuclear ribnucleoprotein particles. Biochemistry (1973) 1.54
Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells. Mol Cell Biol (1983) 1.54
Small nuclear RNA U2 is base-paired to heterogeneous nuclear RNA. Science (1982) 1.53
Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proc Natl Acad Sci U S A (1990) 1.50
Eukaryotic small ribonucleoproteins. Anti-La human autoantibodies react with U1 RNA-protein complexes. J Biol Chem (1984) 1.46
Comparison of mitotic phenomena and effects induced by hypertonic solutions in HeLa cells. J Cell Biol (1970) 1.37
Precursors of U4 small nuclear RNA. J Cell Biol (1984) 1.36
Transcription of a human U6 small nuclear RNA gene in vivo withstands deletion of intragenic sequences but not of an upstream TATATA box. Nucleic Acids Res (1989) 1.36
Transcription boundaries of U1 small nuclear RNA. Mol Cell Biol (1985) 1.36
Review: movement of mRNA from transcription site to nuclear pores. J Struct Biol (2000) 1.35
Messenger RNA processing and nuclear structure: isolation of nuclear ribonucleoprotein particles containing beta-globin messenger RNA precursors. J Cell Biol (1980) 1.35
Nuclear RNA-protein interactions and messenger RNA processing. J Cell Biol (1983) 1.33
Nonhistone chromosomal proteins in synchronized HeLa cells. Proc Natl Acad Sci U S A (1972) 1.32
Secondary structure of heterogeneous nuclear RNA: two classes of double-stranded RNA in native ribonucleoprotein. Proc Natl Acad Sci U S A (1977) 1.31
The small nuclear RNAs of Drosophila. J Mol Biol (1984) 1.30
Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA. Proc Natl Acad Sci U S A (1993) 1.28
Diffusional protein transport within the nucleus: a message in the medium. Nat Cell Biol (2000) 1.26
Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1975) 1.25
Pseudouridine formation in U2 small nuclear RNA. Proc Natl Acad Sci U S A (1994) 1.24
Iron: its intracellular localization and possible role in cell division. Proc Natl Acad Sci U S A (1970) 1.20
Gene activation in eukaryotes: are nuclear acidic proteins the cause or the effect? Proc Natl Acad Sci U S A (1974) 1.20
U2 small nuclear RNP assembly in vitro. Nucleic Acids Res (1989) 1.18
Isolation and characterization of ribonucleoprotein particles containing heterogeneous nuclear RNA. Methods Cell Biol (1978) 1.17
U1 small nuclear ribonucleoprotein studied by in vitro assembly. J Cell Biol (1983) 1.16
Ribonucleoprotein organization of eukaryotic RNA. XXXII. U2 small nuclear RNA precursors and their accurate 3' processing in vitro as ribonucleoprotein particles. J Mol Biol (1985) 1.15
Nucleoprotein organization of inverted repeat DNA transcripts in heterogeneous nuclear RNA-ribonucleoprotein particles from HeLa cells. J Mol Biol (1978) 1.15
Sequence complexity of nuclear and messenger RNA in HeLa cells. J Mol Biol (1980) 1.15
Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A (1979) 1.15
Chromatin structure and the cell division cycle. Actinomycin binding in synchronized HeLa cells. J Cell Biol (1972) 1.11
Accurate and efficient 3' processing of U2 small nuclear RNA precursor in a fractionated cytoplasmic extract. Mol Cell Biol (1987) 1.10
A 62,000 molecular weight spliceosome protein crosslinks to the intron polypyrimidine tract. Nucleic Acids Res (1990) 1.10
In vitro assembly of a pre-messenger ribonucleoprotein. Proc Natl Acad Sci U S A (1983) 1.09
Evidence for a role of RNA in eukaryotic chromosome structure. Metabolically stable, small nuclear RNA species are covalently linked to chromosomal DNA in HeLa cells. J Mol Biol (1979) 1.07
A special class of non-histone protein tightly complexed with template-inactive DNA in chromatin. Biochemistry (1975) 1.07
Relationship between protein synthesis and ribosome assembly in HeLa cells. J Mol Biol (1971) 1.06
A 7-methylguanosine cap commits U3 and U8 small nuclear RNAs to the nucleolar localization pathway. Nucleic Acids Res (1998) 1.05
Identification of proteins that bind tightly to pre-mRNA during in vitro splicing. Proc Natl Acad Sci U S A (1986) 1.03
RNA processing and ribonucleoprotein assembly studied in vivo by RNA transfection. Proc Natl Acad Sci U S A (1990) 1.03
Ribonucleoprotein organization of eukaryotic RNA. XXXI. Structure of the U1 small nuclear ribonucleoprotein. J Mol Biol (1984) 0.99
Ribonucleoprotein organization of eukaryotic RNA. XXX. Evidence that U1 small nuclear RNA is a ribonucleoprotein when base-paired with pre-messenger RNA in vivo. J Mol Biol (1984) 0.99
Isolation and characterization of chromatin from the cellular slime mold, Dictyostelium discoideum. Biochemistry (1977) 0.95
A human U2 RNA mutant stalled in 3' end processing is impaired in nuclear import. Nucleic Acids Res (1999) 0.95
A beta-like DNA polymerase activity in the slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1980) 0.94
A method for improving synchrony in the G2 phase of the cell cycle. J Cell Biol (1971) 0.94
Ribonucleoprotein organization of eukaryotic RNA. XV. Different nucleoprotein structures of globin messenger RNA sequences in nuclear and polyribosomal ribonucleoprotein particles. J Mol Biol (1981) 0.94
Messenger RNA biosynthesis and nuclear structure. Am Sci (1981) 0.93
Messenger RNA sequences in nuclear ribonucleoprotein particles are complexed with protein as shown by nuclease protection. J Mol Biol (1981) 0.92
Heterogeneous nuclear RNA secondary structure: oligo (U) sequences base-paired with poly (A) and their possible role as binding sites for heterogeneous nuclear RNA-specific proteins. Proc Natl Acad Sci U S A (1977) 0.91
3' processing of human pre-U2 small nuclear RNA: a base-pairing interaction between the 3' extension of the precursor and an internal region. Mol Cell Biol (1997) 0.90
G2-population cells in mouse kidney and duodenum and their behavior during the cell division cycle. Exp Cell Res (1970) 0.88
Assembly of nuclear ribonucleoprotein particles during in vitro transcription. Proc Natl Acad Sci U S A (1982) 0.88
Photochemical cross-linking of secondary structure in HeLa cell heterogeneous nuclear RNA in situ 1. Nucleic Acids Res (1979) 0.88
Chromatin structure and gene transcription: nucleosomes permit a new synthesis. Int Rev Cytol (1978) 0.87
The U2 small nuclear ribonucleoprotein particle associates with nuclear factors in a pre-mRNA independent reaction. J Biol Chem (1991) 0.87
RNA synthesis in HeLa cells. Pattern in hypertonic medium and its similarity to synthesis during G2-prophase. J Cell Biol (1970) 0.86
A discrete 3' region of U6 small nuclear RNA modulates the phosphorylation cycle of the C1 heterogeneous nuclear ribonucleoprotein particle protein. Mol Cell Biol (1996) 0.86
RNA-dependent phosphorylation of a nuclear RNA binding protein. Proc Natl Acad Sci U S A (1997) 0.85
Phosphorylation of messenger RNA-bound proteins in HeLa cells. Biochem Biophys Res Commun (1975) 0.84
The C-group heterogeneous nuclear ribonucleoprotein proteins bind to the 5' stem-loop of the U2 small nuclear ribonucleoprotein particle. J Biol Chem (1996) 0.84
Chromosomal proteins: tightly bound nucleic acid and its bearing on the measurement of nonhistone protein phosphorylation. Anal Biochem (1976) 0.83
Absence of translational control of histone synthesis during the HeLa cell life cycle. J Cell Biol (1970) 0.81
An intron-containing Schizosaccharomyces pombe U6 RNA gene can be transcribed by human RNA polymerase III. J Mol Biol (1990) 0.79
Evidence for an association between U1 RNA and interspersed repeat single-copy RNAs in the cytoplasm of sea urchin eggs. Development (1987) 0.79
A sequence related to 4.5 S RNA and the B1 family of repeated DNA in the 5' flanking region of the mouse beta-globin gene. J Mol Biol (1983) 0.78
Use of diphenylamine as a colorimetric reagent for ribonucleic acid. Anal Biochem (1969) 0.78
On the role of ions in mitosis. In Vitro (1974) 0.78
Is the nucleus in need of translation? Trends Cell Biol (2001) 0.78
Metabolic stability of messenger ribonucleoprotein in HeLa cells. Biochim Biophys Acta (1975) 0.77
Biotinylated antisense methylphosphonate oligodeoxynucleotides. Inhibition of spliceosome assembly and affinity selection of U1 and U2 small nuclear RNPs. J Biol Chem (1991) 0.77
Ternary solvents to investigate proteins at zub-zero temperatures. Biochimie (1975) 0.76
Human cell lines expressing hormone regulated T7 RNA polymerase localized at distinct intranuclear sites. Gene (2001) 0.76