Published in Proc Natl Acad Sci U S A on June 01, 1986
Regulation of tissue-specific alternative splicing: exon-specific cis-elements govern the splicing of leukocyte common antigen pre-mRNA. EMBO J (1989) 2.41
Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs. Nucleic Acids Res (1990) 1.68
Sequences downstream of AAUAAA signals affect pre-mRNA cleavage and polyadenylation in vitro both directly and indirectly. Mol Cell Biol (1989) 1.67
Assembly of pre-mRNA splicing complex is cap dependent. Nucleic Acids Res (1987) 1.30
A 62,000 molecular weight spliceosome protein crosslinks to the intron polypyrimidine tract. Nucleic Acids Res (1990) 1.10
A discrete 3' region of U6 small nuclear RNA modulates the phosphorylation cycle of the C1 heterogeneous nuclear ribonucleoprotein particle protein. Mol Cell Biol (1996) 0.86
Purified U5 small nuclear ribonucleoprotein can relieve the inhibition of spliceosome assembly and splicing by snRNP-free nuclear proteins. Nucleic Acids Res (1989) 0.81
In vitro processing of the human growth hormone primary transcript. Nucleic Acids Res (1987) 0.81
Intron sequences and the length of the downstream second exon affect the binding of hnRNP C proteins in an in vitro splicing reaction. Nucleic Acids Res (1988) 0.79
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus. Proc Natl Acad Sci U S A (1979) 14.61
Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell (1984) 12.30
Human beta-globin pre-mRNA synthesized in vitro is accurately spliced in Xenopus oocyte nuclei. Cell (1983) 9.77
Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Cell (1984) 9.13
The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro. Cell (1983) 9.00
U2 as well as U1 small nuclear ribonucleoproteins are involved in premessenger RNA splicing. Cell (1985) 8.85
Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences. Cell (1985) 7.49
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell (1985) 6.85
A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell (1985) 6.27
The "spliceosome": yeast pre-messenger RNA associates with a 40S complex in a splicing-dependent reaction. Science (1985) 5.82
Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. Science (1986) 5.52
Identification and characterization of the packaging proteins of core 40S hnRNP particles. Cell (1977) 5.50
The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies. J Biol Chem (1984) 4.68
A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing. Cell (1982) 4.22
Structural organization of nuclear complexes containing DNA-like RNA. J Mol Biol (1968) 3.38
Proteins associated with heterogeneous nuclear RNA in eukaryotic cells. J Mol Biol (1974) 3.13
Characterization of the non-histone nuclear proteins associated with rapidly labeled heterogeneous nuclear RNA. J Biol Chem (1977) 2.84
Morphological studies of transcription. Acta Endocrinol Suppl (Copenh) (1972) 2.81
RNP particles at splice junction sequences on Drosophila chorion transcripts. Cell (1985) 2.69
Monoclonal antibodies to heterogeneous nuclear RNA-protein complexes. The core proteins comprise a conserved group of related polypeptides. J Biol Chem (1984) 2.43
Ultraviolet light-induced crosslinking of mRNA to proteins. Nucleic Acids Res (1979) 2.38
Structure of nuclear ribonucleoprotein: heterogeneous nuclear RNA is complexed with a major sextet of proteins in vivo. Proc Natl Acad Sci U S A (1983) 2.19
Some properties of RNA:protein complexes from the nucleus of eukaryotic cells. Cold Spring Harb Symp Quant Biol (1974) 2.11
Correlation of hnRNP structure and nascent transcript cleavage. Cell (1981) 2.06
Ribonucleoprotein structure in nascent hnRNA is nonrandom and sequence-dependent. Cell (1980) 1.93
Subnuclear particles containing a small nuclear RNA and heterogeneous nuclear RNA. J Mol Biol (1981) 1.90
Nuclear ribonucleoprotein particles probed in living cells. Proc Natl Acad Sci U S A (1981) 1.79
Small nuclear ribonucleoproteins of Drosophila: identification of U1 RNA-associated proteins and their behavior during heat shock. Mol Cell Biol (1982) 1.70
Transcription-dependent localization of U1 and U2 small nuclear ribonucleoproteins at major sites of gene activity in polytene chromosomes. J Mol Biol (1984) 1.66
cDNA cloning of a human autoimmune nuclear ribonucleoprotein antigen. Proc Natl Acad Sci U S A (1985) 1.59
Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells. Mol Cell Biol (1983) 1.54
Immunofluorescent localization of the proteins of nuclear ribonucleoprotein complexes. J Cell Biol (1980) 1.53
Messenger RNA processing and nuclear structure: isolation of nuclear ribonucleoprotein particles containing beta-globin messenger RNA precursors. J Cell Biol (1980) 1.35
Nuclear RNA-protein interactions and messenger RNA processing. J Cell Biol (1983) 1.33
Nucleoprotein organization of inverted repeat DNA transcripts in heterogeneous nuclear RNA-ribonucleoprotein particles from HeLa cells. J Mol Biol (1978) 1.15
In vitro assembly of a pre-messenger ribonucleoprotein. Proc Natl Acad Sci U S A (1983) 1.09
The nucleolus, chromosomes, and visualization of genetic activity. J Cell Biol (1981) 1.04
Sequence dependent interaction of hnRNP proteins with late adenoviral transcripts. Nucleic Acids Res (1982) 1.02
Non-random localization of ribonucleoprotein (RNP) structures within an adenovirus mRNA precursor. Nucleic Acids Res (1982) 0.99
Ribonucleoprotein organization of eukaryotic RNA. XXXI. Structure of the U1 small nuclear ribonucleoprotein. J Mol Biol (1984) 0.99
Ribonucleoprotein organization of eukaryotic RNA. XXX. Evidence that U1 small nuclear RNA is a ribonucleoprotein when base-paired with pre-messenger RNA in vivo. J Mol Biol (1984) 0.99
RNA splicing in neurospora mitochondria: structure of the unspliced 35S precursor ribosomal RNA detected by psoralen cross-linking. Cell (1983) 0.98
Secondary structure of splice sites in adenovirus mRNA precursors. Nucleic Acids Res (1984) 0.96
Centrifugation of nuclear ribonucleoprotein particles of sea urchin embryos in cesium sulfate. Biochemistry (1973) 0.96
Specific regions of the intervening sequences of beta-globin RNA are resistant to nuclease in 50S heterogeneous nuclear RNA-protein complexes. Proc Natl Acad Sci U S A (1985) 0.84
Induction of AIDS in rhesus monkeys by molecularly cloned simian immunodeficiency virus. Science (1990) 8.07
Intranuclear diffusion and hybridization state of oligonucleotides measured by fluorescence correlation spectroscopy in living cells. Proc Natl Acad Sci U S A (1998) 3.36
U6 small nuclear RNA is transcribed by RNA polymerase III. Proc Natl Acad Sci U S A (1986) 3.14
Proteins associated with heterogeneous nuclear RNA in eukaryotic cells. J Mol Biol (1974) 3.13
Upstream elements required for efficient transcription of a human U6 RNA gene resemble those of U1 and U2 genes even though a different polymerase is used. Genes Dev (1988) 2.55
Base-pairing interactions between small nuclear RNAs and nuclear RNA precursors as revealed by psoralen cross-linking in vivo. Cell (1981) 2.49
Structure of nuclear ribonucleoprotein: identification of proteins in contact with poly(A)+ heterogeneous nuclear RNA in living HeLa cells. J Cell Biol (1981) 2.42
Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells. Curr Biol (1999) 2.20
Structure of nuclear ribonucleoprotein: heterogeneous nuclear RNA is complexed with a major sextet of proteins in vivo. Proc Natl Acad Sci U S A (1983) 2.19
Comparison of proteins bound to heterogeneous nuclear RNA and messenger RNA in HeLa cells. J Mol Biol (1975) 2.00
Nuclear domains of the RNA subunit of RNase P. J Cell Sci (1997) 1.99
The Mr 70,000 protein of the U1 small nuclear ribonucleoprotein particle binds to the 5' stem-loop of U1 RNA and interacts with Sm domain proteins. Proc Natl Acad Sci U S A (1988) 1.98
Signal recognition particle components in the nucleolus. Proc Natl Acad Sci U S A (2000) 1.95
Regulated transcription of the genes for actin and heat-shock proteins in cultured Drosophila cells. J Cell Biol (1981) 1.95
Reconstitution of the U1 small nuclear ribonucleoprotein particle. Mol Cell Biol (1987) 1.94
Chromatin structure and the cell cycle. Proc Natl Acad Sci U S A (1972) 1.91
Localization of signal recognition particle RNA in the nucleolus of mammalian cells. Proc Natl Acad Sci U S A (1998) 1.89
Intracellular site of U1 small nuclear RNA processing and ribonucleoprotein assembly. J Cell Biol (1984) 1.81
Nuclear ribonucleoprotein particles probed in living cells. Proc Natl Acad Sci U S A (1981) 1.79
Dynamic localization of RNase MRP RNA in the nucleolus observed by fluorescent RNA cytochemistry in living cells. J Cell Biol (1995) 1.77
Localization of pre-messenger RNA at discrete nuclear sites. Proc Natl Acad Sci U S A (1991) 1.74
Poly (A)-rich ribonucleoprotein complexes from HeLa cell messenger RNA. J Biol Chem (1976) 1.74
Small nuclear ribonucleoproteins of Drosophila: identification of U1 RNA-associated proteins and their behavior during heat shock. Mol Cell Biol (1982) 1.70
Crosslinking of hnRNP proteins to pre-mRNA requires U1 and U2 snRNPs. Nucleic Acids Res (1990) 1.68
Ribonucleoprotein organization of polyadenylate sequences in HeLa cell heterogeneous nuclear RNA. J Mol Biol (1975) 1.67
Transcription-dependent localization of U1 and U2 small nuclear ribonucleoproteins at major sites of gene activity in polytene chromosomes. J Mol Biol (1984) 1.66
Protein binding sites are conserved in U1 small nuclear RNA from insects and mammals. Proc Natl Acad Sci U S A (1983) 1.63
cDNA cloning of a human autoimmune nuclear ribonucleoprotein antigen. Proc Natl Acad Sci U S A (1985) 1.59
U1 small nuclear ribonucleoprotein particle-specific proteins interact with the first and second stem-loops of U1 RNA, with the A protein binding directly to the RNA independently of the 70K and Sm proteins. Mol Cell Biol (1989) 1.56
Chromatin: its isolation from cultured mammalian cells with particular reference to contamination by nuclear ribnucleoprotein particles. Biochemistry (1973) 1.54
Heat shock alters nuclear ribonucleoprotein assembly in Drosophila cells. Mol Cell Biol (1983) 1.54
Small nuclear RNA U2 is base-paired to heterogeneous nuclear RNA. Science (1982) 1.53
Site-specific excision from RNA by RNase H and mixed-phosphate-backbone oligodeoxynucleotides. Proc Natl Acad Sci U S A (1990) 1.50
Eukaryotic small ribonucleoproteins. Anti-La human autoantibodies react with U1 RNA-protein complexes. J Biol Chem (1984) 1.46
Neural cell adhesion molecule-stimulated neurite outgrowth depends on activation of protein kinase C and the Ras-mitogen-activated protein kinase pathway. J Neurosci (2000) 1.38
The level of urokinase-type plasminogen activator receptor is increased in serum of ovarian cancer patients. Cancer Res (1998) 1.38
Comparison of mitotic phenomena and effects induced by hypertonic solutions in HeLa cells. J Cell Biol (1970) 1.37
Precursors of U4 small nuclear RNA. J Cell Biol (1984) 1.36
Transcription of a human U6 small nuclear RNA gene in vivo withstands deletion of intragenic sequences but not of an upstream TATATA box. Nucleic Acids Res (1989) 1.36
Transcription boundaries of U1 small nuclear RNA. Mol Cell Biol (1985) 1.36
Review: movement of mRNA from transcription site to nuclear pores. J Struct Biol (2000) 1.35
Messenger RNA processing and nuclear structure: isolation of nuclear ribonucleoprotein particles containing beta-globin messenger RNA precursors. J Cell Biol (1980) 1.35
Nuclear RNA-protein interactions and messenger RNA processing. J Cell Biol (1983) 1.33
Nonhistone chromosomal proteins in synchronized HeLa cells. Proc Natl Acad Sci U S A (1972) 1.32
Secondary structure of heterogeneous nuclear RNA: two classes of double-stranded RNA in native ribonucleoprotein. Proc Natl Acad Sci U S A (1977) 1.31
East-West gradient in the incidence of inflammatory bowel disease in Europe: the ECCO-EpiCom inception cohort. Gut (2013) 1.30
The small nuclear RNAs of Drosophila. J Mol Biol (1984) 1.30
Serine/threonine phosphorylation regulates binding of C hnRNP proteins to pre-mRNA. Proc Natl Acad Sci U S A (1993) 1.28
Diffusional protein transport within the nucleus: a message in the medium. Nat Cell Biol (2000) 1.26
Ribonucleoprotein particles containing heterogeneous nuclear RNA in the cellular slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1975) 1.25
Pseudouridine formation in U2 small nuclear RNA. Proc Natl Acad Sci U S A (1994) 1.24
Assessment of heritability for personality, based on a short-form of the Eysenck Personality Inventory: a study of 12,898 twin pairs. Behav Genet (1980) 1.24
A pilot Swedish twin study of affective illness, including hospital- and population-ascertained subsamples. Arch Gen Psychiatry (1993) 1.22
A 21S enzyme complex from HeLa cells that functions in simian virus 40 DNA replication in vitro. Biochemistry (1990) 1.21
A cross-national self-report measure of depressive symptomatology. Int Psychogeriatr (1993) 1.21
Iron: its intracellular localization and possible role in cell division. Proc Natl Acad Sci U S A (1970) 1.20
Gene activation in eukaryotes: are nuclear acidic proteins the cause or the effect? Proc Natl Acad Sci U S A (1974) 1.20
The second European evidenced-based consensus on reproduction and pregnancy in inflammatory bowel disease. J Crohns Colitis (2015) 1.19
Genetic and environmental influences on blood pressure in elderly twins. Hypertension (1994) 1.19
An empirical test of telephone screening to identify potential dementia cases. Int Psychogeriatr (1995) 1.18
U2 small nuclear RNP assembly in vitro. Nucleic Acids Res (1989) 1.18
Isolation and characterization of ribonucleoprotein particles containing heterogeneous nuclear RNA. Methods Cell Biol (1978) 1.17
U1 small nuclear ribonucleoprotein studied by in vitro assembly. J Cell Biol (1983) 1.16
Isolation and partial characterization of a lentivirus from talapoin monkeys (Myopithecus talapoin). Virology (1999) 1.16
Ribonucleoprotein organization of eukaryotic RNA. XXXII. U2 small nuclear RNA precursors and their accurate 3' processing in vitro as ribonucleoprotein particles. J Mol Biol (1985) 1.15
Nucleoprotein organization of inverted repeat DNA transcripts in heterogeneous nuclear RNA-ribonucleoprotein particles from HeLa cells. J Mol Biol (1978) 1.15
Sequence complexity of nuclear and messenger RNA in HeLa cells. J Mol Biol (1980) 1.15
Heterogeneous nuclear RNA double-stranded regions probed in living HeLa cells by crosslinking with the psoralen derivative aminomethyltrioxsalen. Proc Natl Acad Sci U S A (1979) 1.15
Chromatin structure and the cell division cycle. Actinomycin binding in synchronized HeLa cells. J Cell Biol (1972) 1.11
Accurate and efficient 3' processing of U2 small nuclear RNA precursor in a fractionated cytoplasmic extract. Mol Cell Biol (1987) 1.10
A 62,000 molecular weight spliceosome protein crosslinks to the intron polypyrimidine tract. Nucleic Acids Res (1990) 1.10
In vitro assembly of a pre-messenger ribonucleoprotein. Proc Natl Acad Sci U S A (1983) 1.09
Pregnancy outcome in inflammatory bowel disease: prospective European case-control ECCO-EpiCom study, 2003-2006. Aliment Pharmacol Ther (2011) 1.07
Evidence for a role of RNA in eukaryotic chromosome structure. Metabolically stable, small nuclear RNA species are covalently linked to chromosomal DNA in HeLa cells. J Mol Biol (1979) 1.07
A special class of non-histone protein tightly complexed with template-inactive DNA in chromatin. Biochemistry (1975) 1.07
Humoral immune reactivity to feline leukemia virus and associated antigens in cats naturally infected with feline leukemia virus. Cancer Res (1980) 1.06
Relationship between protein synthesis and ribosome assembly in HeLa cells. J Mol Biol (1971) 1.06
A 7-methylguanosine cap commits U3 and U8 small nuclear RNAs to the nucleolar localization pathway. Nucleic Acids Res (1998) 1.05
U2 small nuclear RNA 3' end formation is directed by a critical internal structure distinct from the processing site. Mol Cell Biol (1993) 1.04
Specificity assessment of feline T-lymphotropic lentivirus serology. Zentralbl Veterinarmed B (1988) 1.03
RNA processing and ribonucleoprotein assembly studied in vivo by RNA transfection. Proc Natl Acad Sci U S A (1990) 1.03
Complementation between urokinase-producing and receptor-producing cells in extracellular matrix degradation. Cell Regul (1991) 1.03
Detection of feline immunodeficiency virus (FIV) nucleic acids in FIV-seronegative cats. J Virol (1992) 1.01
N-linked glycosylation of the ligand-binding domain of the human urokinase receptor contributes to the affinity for its ligand. J Biol Chem (1993) 1.00
Ribonucleoprotein organization of eukaryotic RNA. XXXI. Structure of the U1 small nuclear ribonucleoprotein. J Mol Biol (1984) 0.99
Differential response to gefitinib of cells expressing normal EGFR and the mutant EGFRvIII. Br J Cancer (2005) 0.99
Ribonucleoprotein organization of eukaryotic RNA. XXX. Evidence that U1 small nuclear RNA is a ribonucleoprotein when base-paired with pre-messenger RNA in vivo. J Mol Biol (1984) 0.99
Small nuclear RNAs in the ciliate Tetrahymena. Nucleic Acids Res (1985) 0.98
A human U2 RNA mutant stalled in 3' end processing is impaired in nuclear import. Nucleic Acids Res (1999) 0.95
Isolation and characterization of chromatin from the cellular slime mold, Dictyostelium discoideum. Biochemistry (1977) 0.95
A beta-like DNA polymerase activity in the slime mold Dictyostelium discoideum. Proc Natl Acad Sci U S A (1980) 0.94
A soluble, ligand binding mutant of the human urokinase plasminogen activator receptor. J Biol Chem (1991) 0.94
Urokinase-urokinase receptor interaction: non-mitogenic signal transduction in human epidermal cells. Biochem Biophys Res Commun (1993) 0.94
A method for improving synchrony in the G2 phase of the cell cycle. J Cell Biol (1971) 0.94
Ribonucleoprotein organization of eukaryotic RNA. XV. Different nucleoprotein structures of globin messenger RNA sequences in nuclear and polyribosomal ribonucleoprotein particles. J Mol Biol (1981) 0.94
Messenger RNA biosynthesis and nuclear structure. Am Sci (1981) 0.93
Messenger RNA sequences in nuclear ribonucleoprotein particles are complexed with protein as shown by nuclease protection. J Mol Biol (1981) 0.92
Molecular comparison of retroviruses associated with human and simian AIDS. Hematol Oncol (1985) 0.91
Heterogeneous nuclear RNA secondary structure: oligo (U) sequences base-paired with poly (A) and their possible role as binding sites for heterogeneous nuclear RNA-specific proteins. Proc Natl Acad Sci U S A (1977) 0.91