Published in Am J Hum Genet on July 01, 1978
Protein measurement with the Folin phenol reagent. J Biol Chem (1951) 1743.91
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels. Eur J Biochem (1974) 113.22
Analysis of bacteriophage T7 early RNAs and proteins on slab gels. J Mol Biol (1973) 30.17
Use of a mixture of proteinase-free collagenases for the specific assay of radioactive collagen in the presence of other proteins. Biochemistry (1971) 7.39
Cell surface proteins and malignant transformation. Biochim Biophys Acta (1976) 4.33
Interaction of soluble fibroblast surface antigen with fribrinogen and fibrin. J Exp Med (1975) 3.91
The in vitro differentiation of mast cells. Cultures of cells from immunized mouse lymph nodes and thoracic duct lymph on fibroblast monolayers. J Cell Biol (1967) 3.14
Altered relation of two collagen types in osteogenesis imperfecta. N Engl J Med (1977) 2.93
Density and cell cycle dependence of cell surface proteins in hamster fibroblasts. Cell (1974) 2.13
Flow cytofluorometric analysis of cell cycle distributions using propidium iodide. Properties of the method and mathematical analysis of the data. J Cell Biol (1976) 1.81
Dimethyl sulfoxide enhances polyethylene glycol-mediated somatic cell fusion. Somatic Cell Genet (1976) 1.78
Suppression of human nucleolus organizer activity in mouse-human somatic hybrid cells. Exp Cell Res (1976) 1.62
Suppression of production of mouse 28S ribosomal RNA in mouse-human hybrids segregating mouse chromosomes. Proc Natl Acad Sci U S A (1977) 1.60
Differential staining of the satellite regions of human acrocentric chromosomes. Experientia (1975) 1.49
Dominance of the senescent phenotype in heterokaryons between replicative and post-replicative human fibroblast-like cells. Proc Natl Acad Sci U S A (1974) 1.45
Synthesis of collagen and hyaluronic acid by fibroblast hybrids. Proc Natl Acad Sci U S A (1966) 1.38
Frequency of satellite association of human chromosomes is correlated with amount of Ag-staining of the nucleolus organizer region. Am J Hum Genet (1977) 1.30
Cultivated cells from diagnostic amniocentesis in second trimester pregnancies. I. Clonal morphology and growth potential. Pediatr Res (1974) 1.29
Isolation and analysis of somatic hybrids derived from two human diploid cells. Proc Natl Acad Sci U S A (1974) 1.18
Parasexual cycle in cultivated human somatic cells. Science (1969) 1.13
A technique for in situ karyotyping of primary amniotic fluid cell cultures. Humangenetik (1975) 1.02
Differentiation in human amniotic fluid cell cultures: I: Collagen production. J Med Genet (1977) 1.00
Cultivated cells from diagnostic amniocentesis in second trimester pregnancies. III. The fetal urine as a potential source of clonable cells. Humangenetik (1975) 0.97
USE OF TRIS(HYDROXYMETHYL)AMINOMETHANE BUFFERS IN CULTURES OF DIPLOID HUMAN FIBROBLASTS. Proc Soc Exp Biol Med (1964) 0.96
Visualization of ribosomal gene activity: silver stains proteins associated with rRNA transcribed from oocyte chromosomes. Chromosoma (1977) 0.91
Attempted hybridizations with senescent human fibroblasts. J Cell Physiol (1973) 0.89
Non-selective isolation, stability and longevity of hybrids between normal human somatic cells. Nature (1975) 0.78
Positional cloning of the Werner's syndrome gene. Science (1996) 10.98
Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype. Lab Invest (1970) 6.44
Structurally distinct collagen types. Annu Rev Biochem (1980) 6.43
Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine (Baltimore) (1966) 6.15
The elastic fiber. I. The separation and partial characterization of its macromolecular components. J Cell Biol (1969) 4.51
The nature of the intramolecular cross-links in collagen. The separation and characterization of peptides from the cross-link region of rat skin collagen. Biochemistry (1966) 4.04
The Werner syndrome protein is a DNA helicase. Nat Genet (1997) 4.03
Temporal processing deficits of language-learning impaired children ameliorated by training. Science (1996) 3.80
Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc Natl Acad Sci U S A (1989) 3.55
Mice that lack thrombospondin 2 display connective tissue abnormalities that are associated with disordered collagen fibrillogenesis, an increased vascular density, and a bleeding diathesis. J Cell Biol (1998) 3.27
An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis. Am Rev Respir Dis (1989) 3.12
Similar progression of diabetic retinopathy with insulin glargine and neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes: a long-term, randomised, open-label study. Diabetologia (2009) 2.98
Evidence for procollagen, a biosynthetic precursors of collagen. Proc Natl Acad Sci U S A (1971) 2.96
Deficient neurogenesis in forebrain-specific presenilin-1 knockout mice is associated with reduced clearance of hippocampal memory traces. Neuron (2001) 2.92
Correlation of procollagen mRNA levels in normal and transformed chick embryo fibroblasts with different rates of procollagen synthesis. Biochemistry (1978) 2.85
Cleavage at Asn-Gly bonds with hydroxylamine. Methods Enzymol (1977) 2.80
Transforming growth factor beta increases mRNA for matrix proteins both in the presence and in the absence of changes in mRNA stability. Proc Natl Acad Sci U S A (1988) 2.73
Genetic syndromes in man with potential relevance to the pathobiology of aging. Birth Defects Orig Artic Ser (1978) 2.66
Clinical parameters do not adequately predict outcome in necrotizing enterocolitis: a multi-institutional study. J Perinatol (2008) 2.64
Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell (1989) 2.61
The biosynthesis of collagen. Annu Rev Biochem (1974) 2.50
Chemical generation of nitric oxide in the mouth from the enterosalivary circulation of dietary nitrate. Nat Med (1995) 2.50
Extracellular proteins that modulate cell-matrix interactions. SPARC, tenascin, and thrombospondin. J Biol Chem (1991) 2.47
Thrombospondin: synthesis and secretion by cells in culture. J Cell Biol (1982) 2.33
PAPYRUS 3.0: DICOM-compatible file format. Med Inform (Lond) (1995) 2.32
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nat Med (1999) 2.25
Isolation and characterization of a glycoprotein secreted by aortic endothelial cells in culture. Apparent identity with platelet thrombospondin. J Biol Chem (1981) 2.25
Light microscopic immunolocation of thrombospondin in human tissues. J Histochem Cytochem (1985) 2.20
Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2. J Biol Chem (2000) 2.18
Control of Drosophila body pattern by the hunchback morphogen gradient. Cell (1992) 2.16
Association of an apolipoprotein CII allele with familial dementia of the Alzheimer type. J Neurogenet (1987) 2.12
Control of smooth muscle cell growth by components of the extracellular matrix: autocrine role for thrombospondin. Proc Natl Acad Sci U S A (1986) 2.10
Interdependence of cortical thymic epithelial cell differentiation and T-lineage commitment. Proc Natl Acad Sci U S A (1998) 2.10
Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission. Dev Dyn (1997) 2.05
Platelet-derived growth factor and heparin-like glycosaminoglycans regulate thrombospondin synthesis and deposition in the matrix by smooth muscle cells. J Cell Biol (1985) 2.05
Interactions of surfactant protein D with bacterial lipopolysaccharides. Surfactant protein D is an Escherichia coli-binding protein in bronchoalveolar lavage. J Clin Invest (1992) 2.04
Similar risk of malignancy with insulin glargine and neutral protamine Hagedorn (NPH) insulin in patients with type 2 diabetes: findings from a 5 year randomised, open-label study. Diabetologia (2009) 2.04
Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture. J Biol Chem (1984) 2.01
Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis. Proc Natl Acad Sci U S A (1999) 2.01
Borders of parasegments in Drosophila embryos are delimited by the fushi tarazu and even-skipped genes. Nature (1987) 2.00
Genetic heterogeneity of the human glutathione transferases: a complex of gene families. Pharmacol Ther (1990) 1.99
Cell surface-associated structural proteins in connective tissue cells. Proc Natl Acad Sci U S A (1977) 1.99
The Fanconi anaemia group G gene FANCG is identical with XRCC9. Nat Genet (1998) 1.99
Impaired S-phase transit of Werner syndrome cells expressed in lymphoblastoid cell lines. Exp Cell Res (1992) 1.98
Phosphotyrosyl-protein phosphatase. Specific inhibition by Zn. J Biol Chem (1981) 1.95
Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro. Proc Natl Acad Sci U S A (1991) 1.94
Effects of antimicrotubular agents on the secretion of collagen. A biochemical and morphological study. J Cell Biol (1974) 1.93
Differential expression of thrombospondin 1, 2, and 3 during murine development. Dev Dyn (1993) 1.92
Liver transplantation in 100 children: Cambridge and King's College Hospital series. BMJ (1992) 1.90
Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients. Diabetes Care (1990) 1.90
An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants. Hum Genet (1997) 1.88
Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism. Cytogenet Cell Genet (1981) 1.85
Matricellular proteins as modulators of cell-matrix interactions: adhesive defect in thrombospondin 2-null fibroblasts is a consequence of increased levels of matrix metalloproteinase-2. Mol Biol Cell (2000) 1.85
Interactions of thrombospondin with extracellular matrix proteins: selective binding to type V collagen. J Cell Biol (1984) 1.85
Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals. J Neurosci (1997) 1.80
Isolation of a collagen-binding fragment from fibronectin and cold-insoluble globulin. J Biol Chem (1979) 1.80
Accelerated wound healing in mice with a disruption of the thrombospondin 2 gene. J Invest Dermatol (1999) 1.79
Clonal selection, attenuation and differentiation in an in vitro model of hyperplasia. Am J Pathol (1974) 1.78
Characterization of the pro- 1 chain of procollagen. J Biol Chem (1972) 1.78
Dimethyl sulfoxide enhances polyethylene glycol-mediated somatic cell fusion. Somatic Cell Genet (1976) 1.78
Different requirements for homeotic genes in the soma and germ line of Drosophila. Cell (1983) 1.77
Structural studies on human type IV collagen. J Biol Chem (1979) 1.77
Isolation and characterization of the cyanogen bromide peptides from the alpha-1 chain of rat skin collagen. Biochemistry (1967) 1.77
Regulation of collagen gene expression. Prog Nucleic Acid Res Mol Biol (1989) 1.75
Prenatal diagnosis of human genome variation. Annu Rev Genet (1979) 1.73
The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism. J Biol Chem (2001) 1.72
Coordinate transcriptional regulation of type I procollagen genes by Rous sarcoma virus. J Biol Chem (1981) 1.68
Increased activity-regulating and neuroprotective efficacy of alpha-secretase-derived secreted amyloid precursor protein conferred by a C-terminal heparin-binding domain. J Neurochem (1996) 1.66
Adjuvant treatment of colorectal cancer (current expert opinion derived from the Third International Conference: Perspectives in Colorectal Cancer, Dublin, 2001). Eur J Cancer (2002) 1.66
Phenocopies induced with antisense RNA identify the wingless gene. Cell (1987) 1.64
Pulmonary surfactant proteins A and D enhance neutrophil uptake of bacteria. Am J Physiol (1998) 1.62
X-linked cutis laxa: defective cross-link formation in collagen due to decreased lysyl oxidase activity. N Engl J Med (1980) 1.62
The nature and location of intramolecular cross-links in collagen. Proc Natl Acad Sci U S A (1966) 1.60
Separating individual skin conductance responses in a short interstimulus-interval paradigm. J Neurosci Methods (2005) 1.59
Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. J Histochem Cytochem (1993) 1.56
Purification and biochemical characterization of CP4 (SP-D), a collagenous surfactant-associated protein. Biochemistry (1989) 1.55
Sulfated proteoglycans synthesized by vascular endothelial cells in culture. J Biol Chem (1983) 1.55
The amino acid sequence of peptides from the cross-linking region of rat skin collagen. Biochemistry (1967) 1.54
A monoclonal antibody to the carboxyterminal domain of procollagen type I visualizes collagen-synthesizing fibroblasts. Detection of an altered fibroblast phenotype in lungs of patients with pulmonary fibrosis. J Clin Invest (1986) 1.54
Microtubules in transcellular movement of procollagen. Nat New Biol (1972) 1.53
Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group. Am J Hum Genet (1997) 1.52
The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development (1992) 1.52
Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism. EMBO J (2001) 1.51
Surfactant protein D is a divalent cation-dependent carbohydrate-binding protein. J Biol Chem (1990) 1.51
Interspecies comparison of carcionogenic potency. J Toxicol Environ Health (1979) 1.50
Secretory phenotypes of endothelial cells in culture: comparison of aortic, venous, capillary, and corneal endothelium. Arteriosclerosis (1982) 1.49
Increased susceptibility of Down's syndrome fibroblasts to transformation by SV40. Proc Soc Exp Biol Med (1967) 1.49
Interactions of recombinant human pulmonary surfactant protein D and SP-D multimers with influenza A. Am J Physiol (1996) 1.49
Reverse mosaicism in Fanconi anemia: natural gene therapy via molecular self-correction. Cytogenet Genome Res (2002) 1.49
Alzheimer's PS-1 mutation perturbs calcium homeostasis and sensitizes PC12 cells to death induced by amyloid beta-peptide. Neuroreport (1996) 1.48
Presumed trisomy for the short arm of chromosome No. 9 not due to inherited translocation. Humangenetik (1971) 1.48
Symposium on in vitro studies related to atherogenesis. Life histories of hyperplastoid cell lines from aorta and skin. Exp Mol Pathol (1973) 1.47
TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax. Cell Death Differ (2006) 1.47
Altered secretion of type III procollagen in a form of type IV Ehlers-Danlos syndrome. Biochemical studies in cultured fibroblasts. Lab Invest (1981) 1.46
Comparative sequence studies of rat skin and tendon collagen. I. Evidence for incomplete hydroxylation of individual prolyl residues in the normal proteins. Biochemistry (1967) 1.46
Variegated translocation mosaicism in human skin fibroblast cultures. Cytogenet Cell Genet (1975) 1.45