Published in Biochim Biophys Acta on April 30, 1976
Fibronectins: multifunctional modular glycoproteins. J Cell Biol (1982) 8.05
Role of collagenous matrices in the adhesion and growth of cells. J Cell Biol (1981) 5.60
Surface parasitism by Mycoplasma pneumoniae of respiratory epithelium. J Exp Med (1977) 5.35
Ubiquitous cell-surface glycoprotein on tumor cells is proliferation-associated receptor for transferrin. Proc Natl Acad Sci U S A (1981) 4.50
Levels of translatable mRNAs for cell surface protein, collagen precursors, and two membrane proteins are altered in Rous sarcoma virus-transformed chick embryo fibroblasts. Proc Natl Acad Sci U S A (1977) 3.80
Affinity of fibronectin to collagens of different genetic types and to fibrinogen. J Exp Med (1978) 3.46
Synthesis of fibronectin by cultured human endothelial cells. J Exp Med (1978) 2.79
Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed cells. J Cell Biol (1977) 2.40
Codistribution of pericellular matrix proteins in cultured fibroblasts and loss in transformation: fibronectin and procollagen. Proc Natl Acad Sci U S A (1978) 2.32
Extensive disulfide bonding at the mammalian cell surface. Proc Natl Acad Sci U S A (1977) 2.32
Immunological characterization of a major transformation-sensitive fibroblast cell surface glycoprotein. Localization, redistribution, and role in cell shape. J Cell Biol (1978) 2.05
Cell surface-associated structural proteins in connective tissue cells. Proc Natl Acad Sci U S A (1977) 1.99
Identification, localization, and role of fibronectin in cultured bovine endothelial cells. Proc Natl Acad Sci U S A (1978) 1.89
Isolation of a Chinese hamster fibroblast mutant defective in hexose transport and aerobic glycolysis: its use to dissect the malignant phenotype. Proc Natl Acad Sci U S A (1980) 1.86
Fibronectin has a dual role in locomotion and anchorage of primary chick fibroblasts and can promote entry into the division cycle. J Cell Biol (1982) 1.74
Interferon effects on microfilament organization, cellular fibronectin distribution, and cell motility in human fibroblasts. J Cell Biol (1980) 1.65
Functional domain structure of fibronectin. Proc Natl Acad Sci U S A (1980) 1.59
Synthesis and processing of precursor polypeptides to murine mammary tumor virus structural proteins. J Virol (1978) 1.53
Quantitation of a transformation-sensitive, adhesive cell surface glycoprotein. Decrease of several untransformed permanent cell lines. J Cell Biol (1977) 1.48
Induction of fibronectin gene transcription and mRNA is a primary response to growth-factor stimulation of AKR-2B cells. Proc Natl Acad Sci U S A (1988) 1.47
Corrugated attachment membrane in WI-38 fibroblasts: alternating fibronectin fibers and actin-containing focal contacts. Proc Natl Acad Sci U S A (1980) 1.43
Two functionally distinct pools of glycosaminoglycan in the substrate adhesion site of murine cells. J Cell Biol (1978) 1.43
Antigenic distinctions of glycoproteins in plasma and mitochondrial membranes of lymphoid cells neoplastically transformed by simian virus 40. Proc Natl Acad Sci U S A (1977) 1.41
Mobility and distribution of a cell surface glycoprotein and its interaction with other membrane components. Proc Natl Acad Sci U S A (1977) 1.41
Dissociation of fibronectin from gelatin-agarose by amino compounds. Biochem J (1978) 1.38
Mutated beta-actin gene: coexpression with an unmutated allele in a chemically transformed human fibroblast cell line. Proc Natl Acad Sci U S A (1981) 1.36
Identification and isolation of a collagen-binding fragment of the adhesive glycoprotein fibronectin. Proc Natl Acad Sci U S A (1979) 1.32
Changes in surface properties of normal and transformed cells caused by tunicamycin, an inhibitor of protein glycosylation. Proc Natl Acad Sci U S A (1977) 1.32
Direct association of fibronectin and actin molecules in vitro. J Cell Biol (1980) 1.28
The extracellular matrix of normal chick embryo fibroblasts: its effect on transformed chick fibroblasts and its proteolytic degradation by the transformants. J Cell Biol (1985) 1.23
Studies on cell adhesion and recognition. II. The kinetics of cell adhesion and cell spreading on surfaces coated with carbohydrate-reactive proteins (glycosidases and lectins) and fibronectin. J Cell Biol (1981) 1.22
Appearance of fibronectin during the differentiation of cartilage, bone, and bone marrow. J Cell Biol (1981) 1.22
Identification of an adhesion factor for chondrocytes. Proc Natl Acad Sci U S A (1980) 1.21
Adenovirus type 12-induced rat tumor cells of neuroepithelial origin: persistence and expression of the viral genome. J Virol (1980) 1.19
The emergence of integrins: a personal and historical perspective. Matrix Biol (2004) 1.18
Polypeptides of cells transformed by RNA or DNA tumor viruses. Proc Natl Acad Sci U S A (1977) 1.17
Calcific shoulder periarthritis (tendinitis) in adult onset diabetes mellitus: a controlled study. Ann Rheum Dis (1989) 1.16
Comparison of [3H]glucosamine-labeled glycoproteins from human renal cancer and normal kidney epithelial cell cultures by two-dimensional polyacrylamide gel electrophoresis. Proc Natl Acad Sci U S A (1981) 1.12
Amniotic fluid fibronectin. Characterization and synthesis by cells in culture. J Cell Biol (1978) 1.12
Distribution of a major connective tissue protein, fibronectin, in normal and neoplastic human nervous tissue. Acta Neuropathol (1980) 1.11
Role of cell surface carbohydrates and proteins in cell behavior: studies on the biochemical reversion of an N-acetylglucosamine-deficient fibroblast mutant. Proc Natl Acad Sci U S A (1977) 1.09
Incorporation of l-[3H]fucose and d-[3H]glucosamine into cell-surface-associated glycoconjugates in epidermis of cultured pig skin slices. Biochem J (1980) 1.08
Biosynthesis and release of glycoproteins by human skin fibroblasts in culture. Biochem J (1977) 1.08
Enhanced prolidase activity and decreased collagen content in breast cancer tissue. Int J Exp Pathol (2006) 1.04
Regulation of collagen I gene expression by ras. Mol Cell Biol (1992) 1.03
Binding and internalization of thrombin by normal and transformed chick cells. Proc Natl Acad Sci U S A (1977) 1.02
Malignancies of metastatic murine lymphosarcoma cell lines and clones correlate with decreased cell surface display of RNA tumor virus envelope glycoprotein gp70. Proc Natl Acad Sci U S A (1980) 0.98
A fibronectin-like molecule is present in the developing cat cerebral cortex and is correlated with subplate neurons. J Cell Biol (1988) 0.97
Studies of fibronectin matrices in living cells with fluoresceinated gelatin. J Cell Biol (1980) 0.96
Mechanisms of Kirsten murine sarcoma virus transformation-induced changes in the collagen phenotype and synthetic rate of BALB 3T3 cells. Proc Natl Acad Sci U S A (1981) 0.95
Catecholamine hormone receptor differences identified on 3T3 and simian virus-transformed 3T3 cells. Proc Natl Acad Sci U S A (1977) 0.94
Radioiodination studies of tumour cell-surface proteins after different disaggregation procedures. Br J Cancer (1977) 0.94
Absence of fibronectin and presence of plasminogen activator in both normal and malignant human mammary epithelial cells in culture. J Cell Biol (1980) 0.93
Species-specific monoclonal antibodies in the assignment of the gene for human fibronectin to chromosome 2. EMBO J (1982) 0.91
Genetics of the large, external, transformation-sensitive (LETS) protein: assignment of a gene coding for expression of LETS to human chromosome 8. Proc Natl Acad Sci U S A (1978) 0.91
Characterization of cell-surface glycopeptides from mouse cerebral cortex that inhibit cell growth and protein synthesis. Biochem J (1980) 0.91
Comparison of cell-surface glycoproteins of rat hepatomas and embryonic rat liver. Br J Cancer (1977) 0.90
Collagen metabolism disturbances are accompanied by an increase in prolidase activity in lung carcinoma planoepitheliale. Int J Exp Pathol (2000) 0.89
Nontumoral, benign ad malignant stages of transformation of a diploid pig cell line. A review. Can J Comp Med (1981) 0.89
Expression of a high molecular weight cell surface glycoprotein (LETS protein) by preimplantation mouse embryos and teratocarcinoma stem cells. Proc Natl Acad Sci U S A (1978) 0.88
Isolation and characterization of two individual glycoprotein components from human milk-fat-globule membranes. Biochem J (1982) 0.88
Fibronectin in the developing sea urchin embryo. J Cell Biol (1980) 0.86
A common marker for cancer cells? Br J Cancer (1979) 0.86
Loss of type I procollagen gene expression in SV40-transformed human fibroblasts is accompanied by hypermethylation of these genes. Nucleic Acids Res (1982) 0.85
Detection of an early surface change during oncogenic transformation. Proc Natl Acad Sci U S A (1978) 0.85
Lactoperoxidase-catalysed iodination of surface proteins on human melanoma cells. Br J Cancer (1978) 0.84
Regulation of type VI collagen synthesis in transformed mesenchymal cells. Biochem J (1988) 0.83
Tumor-promoter-resistant cells lack trisialoganglioside response. Proc Natl Acad Sci U S A (1982) 0.83
Monovalent antibodies directed to transformation-sensitive membrane components inhibit the process of viral transformation. Proc Natl Acad Sci U S A (1978) 0.82
Effects of sodium butyrate on the membrane glycoconjugates of murine sarcoma virus-transformed rat cells. J Cell Biol (1980) 0.81
Steroid hormones mediate reversible phenotypic transition between transformed and untransformed states in mouse fibroblasts. Proc Natl Acad Sci U S A (1978) 0.81
Polypeptide heterogeneity of hamster and calf fibronectins. Biochem J (1980) 0.81
Protease effects on specific growth properties of normal and transformed baby hamster kidney cells. Proc Natl Acad Sci U S A (1977) 0.80
Isolation and characterization of rat plasma fibronectin. Biochem J (1981) 0.80
Cell-surface radioiodination with the sparingly soluble catalyst Iodogen. Difference between the dividing and non-dividing populations of rodent thymocytes. Biochem J (1981) 0.80
Differences in polyamine availability and insertion into fibronectins released from normal and transformed cells. Biochem J (1983) 0.79
Most iodinatable fibroblast surface proteins accompany the cytoplast membrane during cytochalasin B-mediated enucleation of chick embryo fibroblasts. J Cell Biol (1982) 0.79
Studies on the neuroprotective role of Piper longum in C6 glioma induced rats. Invest New Drugs (2010) 0.79
Aprotinin and growth of Walker 256 carcinosarcoma in the rat. Br J Cancer (1977) 0.77
Surface antigens on human melanoma cells studied with heterologous antisera. Br J Cancer (1980) 0.75
Regulation of growth and gene activity in euploid hybrids between human neonatal fibroblasts and epithelioid amniotic fluid cells. Am J Hum Genet (1978) 0.75
Biosynthesis, surface expression and function of the fibronectin receptor after rat liver cell transformation to tumorigenicity. Biochem J (1993) 0.75
Differing lectin-binding patterns of malignant melanoma and nevocellular and Spitz nevi. Arch Dermatol Res (1987) 0.75
Surface proteins in normal and transformed rat liver epithelial cells in culture. Br J Cancer (1980) 0.75
Analysis of immunoprecipitated surface glycoproteins in measles virions and in membranes of infected cells. J Virol (1978) 0.75
Imperial Cancer Research Fund British Association for Cancer Research. Joint symposium held at the Royal College of Surgeons, Lincolns Inn Fields, London 30 November--1 December 1978. Abstracts of papers. Br J Cancer (1979) 0.75
Analysis of mammary tumour cell metastasis and release of bound n-acetylneuraminic acid. Br J Cancer (1985) 0.75
Endocytosis of the antiprotease aprotinin by Landschütz ascites carcinoma cells and its effects in vitro and in vivo. Br J Cancer (1978) 0.75
Specific response of osteoblast-like cells on hydroxyapatite layer containing serum protein. J Mater Sci Mater Med (2006) 0.75
Lattices of type I collagen select invasive variants of K-ras oncogene-transfected NIH3T3 with less cellular fibronectin. Clin Exp Metastasis (1998) 0.75
Comparative genomics of the eukaryotes. Science (2000) 26.62
Integrins: a family of cell surface receptors. Cell (1987) 21.14
Genomic analysis of metastasis reveals an essential role for RhoC. Nature (2000) 10.11
Fibronectins: multifunctional modular glycoproteins. J Cell Biol (1982) 8.05
Alteration of cell-surface proteins by viral transformation and by proteolysis. Proc Natl Acad Sci U S A (1973) 6.98
Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development (1993) 6.56
Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts. Nature (1999) 6.50
Thrombospondin-1 is a major activator of TGF-beta1 in vivo. Cell (1998) 6.44
Three different fibronectin mRNAs arise by alternative splicing within the coding region. Cell (1983) 6.27
Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice. Cell (1993) 6.05
Fibronectin/integrin interaction induces tyrosine phosphorylation of a 120-kDa protein. Cell Regul (1991) 5.80
Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. J Clin Invest (1999) 5.65
Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin. Cell (1986) 5.29
The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation. J Biol Chem (1999) 4.92
10 nm filaments in normal and transformed cells. Cell (1978) 4.77
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. J Clin Invest (2000) 4.54
Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins. Cell (1996) 4.52
Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development. Development (1995) 4.44
Embryonic mesodermal defects in alpha 5 integrin-deficient mice. Development (1993) 4.22
Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell (1998) 4.20
The structure of human thrombospondin, an adhesive glycoprotein with multiple calcium-binding sites and homologies with several different proteins. J Cell Biol (1986) 4.16
Relationships between fibronectin (LETS protein) and actin. Cell (1978) 4.12
Plakoglobin: a protein common to different kinds of intercellular adhering junctions. Cell (1986) 4.01
Thrombospondin-1 is required for normal murine pulmonary homeostasis and its absence causes pneumonia. J Clin Invest (1998) 4.00
A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis. Proc Natl Acad Sci U S A (1998) 3.54
Lymphoid cells recognize an alternatively spliced segment of fibronectin via the integrin receptor alpha 4 beta 1. Cell (1990) 3.46
Integrin-mediated signals regulated by members of the rho family of GTPases. J Cell Biol (1998) 3.46
Reappearance of an embryonic pattern of fibronectin splicing during wound healing in the adult rat. J Cell Biol (1989) 3.44
Developmental defects in mouse embryos lacking N-cadherin. Dev Biol (1997) 3.39
Restoration of normal morphology, adhesion and cytoskeleton in transformed cells by addition of a transformation-sensitive surface protein. Cell (1977) 3.36
Antibodies to the conserved cytoplasmic domain of the integrin beta 1 subunit react with proteins in vertebrates, invertebrates, and fungi. J Cell Biol (1988) 3.35
Hematopoietic progenitor cell rolling in bone marrow microvessels: parallel contributions by endothelial selectins and vascular cell adhesion molecule 1. J Exp Med (1998) 3.26
Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element. Genes Dev (1994) 3.20
Changes in integrin receptors on oncogenically transformed cells. Cell (1989) 3.09
Sequence and domain structure of talin. Nature (1990) 2.98
Thrombospondin-1 suppresses spontaneous tumor growth and inhibits activation of matrix metalloproteinase-9 and mobilization of vascular endothelial growth factor. Proc Natl Acad Sci U S A (2001) 2.82
Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors. J Cell Biol (1988) 2.72
Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest (2000) 2.68
The combined role of P- and E-selectins in atherosclerosis. J Clin Invest (1998) 2.53
Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers. Proc Natl Acad Sci U S A (1999) 2.47
alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. J Cell Biol (1997) 2.46
Surface distribution of LETS protein in relation to the cytoskeleton of normal and transformed cells. J Cell Biol (1977) 2.40
Self-complementary oligopeptide matrices support mammalian cell attachment. Biomaterials (1995) 2.40
Platelets roll on stimulated endothelium in vivo: an interaction mediated by endothelial P-selectin. Proc Natl Acad Sci U S A (1995) 2.37
Extensive disulfide bonding at the mammalian cell surface. Proc Natl Acad Sci U S A (1977) 2.32
Fibronectin binds to some bacteria but does not promote their uptake by phagocytic cells. Science (1983) 2.31
Cross-linking of fibronectin to sulfated proteoglycans at the cell surface. Cell (1979) 2.28
Plasma fibronectin is synthesized and secreted by hepatocytes. J Biol Chem (1983) 2.25
Targeted mutation of TNF receptor I rescues the RelA-deficient mouse and reveals a critical role for NF-kappa B in leukocyte recruitment. J Immunol (2001) 2.16
Fibronectins are essential for heart and blood vessel morphogenesis but are dispensable for initial specification of precursor cells. Blood (1997) 2.15
Density and cell cycle dependence of cell surface proteins in hamster fibroblasts. Cell (1974) 2.13
Hemostasis in the mouse (Mus musculus): a review. Thromb Haemost (1999) 2.13
A large glycoprotein lost from the surfaces of transformed cells. Ann N Y Acad Sci (1978) 2.11
Precocious mammary gland development in P-cadherin-deficient mice. J Cell Biol (1997) 2.10
Cell-type-specific fibronectin subunits generated by alternative splicing. J Biol Chem (1986) 2.09
Platelets adhere to and translocate on von Willebrand factor presented by endothelium in stimulated veins. Blood (2000) 2.05
An integrin receptor on normal and thrombasthenic platelets that binds thrombospondin. Blood (1989) 2.05
Multiple sites of alternative splicing of the rat fibronectin gene transcript. EMBO J (1987) 2.03
Expression of normal and mutant avian integrin subunits in rodent cells. J Cell Biol (1989) 2.03
Differential requirements for alpha4 integrins during fetal and adult hematopoiesis. Cell (1996) 2.01
A single rat fibronectin gene generates three different mRNAs by alternative splicing of a complex exon. Proc Natl Acad Sci U S A (1984) 2.00
Analysis of platelet adhesion with a radioactive chemical crosslinking reagent: interaction of thrombospondin with fibronectin and collagen. Cell (1982) 1.96
Talin contains three actin-binding sites each of which is adjacent to a vinculin-binding site. J Cell Sci (1996) 1.95
Mapping of the functional determinants of the integrin beta 1 cytoplasmic domain by site-directed mutagenesis. Cell Regul (1990) 1.94
Interaction of fibronectin with its receptor on platelets. Cell (1985) 1.92
alpha 3A beta 1 integrin localizes to focal contacts in response to diverse extracellular matrix proteins. J Cell Sci (1995) 1.88
The location of proteins labeled by the 125I-lactoperoxidase system in the NIL 8 hamster fibroblast. Cell (1975) 1.84
Control of alternative pre-mRNA splicing by distributed pentameric repeats. Proc Natl Acad Sci U S A (1997) 1.82
Hypoxia-induced exocytosis of endothelial cell Weibel-Palade bodies. A mechanism for rapid neutrophil recruitment after cardiac preservation. J Clin Invest (1996) 1.81
Fibronectin localization in the rat glomerulus. J Cell Biol (1980) 1.80
Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos. Development (1997) 1.75
Effects of LETS glycoprotein on cell motility. Cell (1978) 1.69
Novel roles for alpha3beta1 integrin as a regulator of cytoskeletal assembly and as a trans-dominant inhibitor of integrin receptor function in mouse keratinocytes. J Cell Biol (1998) 1.69
Alternative splicing of fibronectin is temporally and spatially regulated in the chicken embryo. Development (1989) 1.69
Biosynthesis and processing of fibronectin in NIL.8 hamster cells. J Biol Chem (1979) 1.66
Defects in hemostasis in P-selectin-deficient mice. Blood (1996) 1.64
Fibronectin regulates assembly of actin filaments and focal contacts in cultured cells via the heparin-binding site in repeat III13. Mol Biol Cell (1999) 1.64
Absence of P-selectin delays fatty streak formation in mice. J Clin Invest (1997) 1.63
Ras activation is necessary for integrin-mediated activation of extracellular signal-regulated kinase 2 and cytosolic phospholipase A2 but not for cytoskeletal organization. J Biol Chem (1996) 1.62
A difference between plasma and cellular fibronectins located with monoclonal antibodies. Cell (1981) 1.62
Transformed mammalian cells secrete specific proteins and phosphoproteins. Cell (1979) 1.62
Effects of cytochalasin B and colchicine on attachment of a major surface protein of fibroblasts. Biochim Biophys Acta (1977) 1.61
Fibronectins. Sci Am (1986) 1.61
A novel alpha integrin subunit associates with betaPS and functions in tissue morphogenesis and movement during Drosophila development. Development (1997) 1.60
Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling. Nat Med (2005) 1.58
Xenopus laevis integrins. Structural conservation and evolutionary divergence of integrin beta subunits. J Biol Chem (1988) 1.57
Interaction of dendritic cells with skin endothelium: A new perspective on immunosurveillance. J Exp Med (1999) 1.55
Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment. Proc Natl Acad Sci U S A (1999) 1.55
Mesodermal development in mouse embryos mutant for fibronectin. Dev Dyn (1996) 1.55
Elements regulating an alternatively spliced exon of the rat fibronectin gene. Mol Cell Biol (1993) 1.54
Alpha4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo. Immunity (1999) 1.51
Overlapping and independent functions of fibronectin receptor integrins in early mesodermal development. Dev Biol (1999) 1.51
On the origin of species of fibronectin. Proc Natl Acad Sci U S A (1985) 1.51
Alternative splicing of chicken fibronectin in embryos and in normal and transformed cells. Mol Cell Biol (1987) 1.51
Role of endothelial selectins in wound repair. Am J Pathol (1997) 1.50
Immunocytochemical localization of fibronectin in embryonic chick trunk and area vasculosa. Dev Biol (1981) 1.48
Alterations in surface proteins in chicken cells transformed by temperature-sensitive mutants of Rous sarcoma virus. Virology (1975) 1.48
Extrajunctional distribution of N-cadherin in cultured human endothelial cells. J Cell Sci (1992) 1.48
Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice. J Exp Med (1995) 1.47
Platelet-endothelial interactions in inflamed mesenteric venules. Blood (1998) 1.46