Published in Proc Natl Acad Sci U S A on December 01, 1993
A mitochondrial homolog of bacterial GrpE interacts with mitochondrial hsp70 and is essential for viability. EMBO J (1994) 1.60
Chaperones divide yeast proteins into classes of expression level and evolutionary rate. Genome Biol Evol (2012) 1.49
Cyclophilin 20 is involved in mitochondrial protein folding in cooperation with molecular chaperones Hsp70 and Hsp60. Mol Cell Biol (1995) 1.29
Role of the chaperonin cofactor Hsp10 in protein folding and sorting in yeast mitochondria. J Cell Biol (1994) 1.10
Expression of stress proteins and mitochondrial chaperonins in chronically stimulated skeletal muscle. Biochem J (1995) 1.08
SCS1, a multicopy suppressor of hsp60-ts mutant alleles, does not encode a mitochondrially targeted protein. Mol Cell Biol (1995) 1.08
Hsp60-independent protein folding in the matrix of yeast mitochondria. EMBO J (1996) 1.02
Molecular chaperones and mitochondrial protein folding. J Bioenerg Biomembr (1997) 0.99
Merging molecular mechanism and evolution: theory and computation at the interface of biophysics and evolutionary population genetics. Curr Opin Struct Biol (2014) 0.89
The MitCHAP-60 disease is due to entropic destabilization of the human mitochondrial Hsp60 oligomer. J Biol Chem (2009) 0.83
The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species. Microbiol Mol Biol Rev (2016) 0.82
The potential role of heat shock proteins in acute spinal cord injury. Eur Spine J (2014) 0.80
Mitochondrial heat shock protein (Hsp) 70 and Hsp10 cooperate in the formation of Hsp60 complexes. J Biol Chem (2015) 0.80
Evidence for a novel ATP-dependent membrane-associated protease in spinach leaf mitochondria. Biochem J (1995) 0.78
9-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, is a potent antifungal agent that inhibits the growth of Cryptococcus neoformans by regulating gene expression. PLoS One (2014) 0.77
Automated high-throughput purification of 6xHis-tagged proteins. J Biomol Tech (2002) 0.77
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem (1976) 903.81
Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. J Biol Chem (1987) 34.69
Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J Biol Chem (1982) 12.07
Homologous plant and bacterial proteins chaperone oligomeric protein assembly. Nature (1988) 9.55
Chaperonin-mediated protein folding at the surface of groEL through a 'molten globule'-like intermediate. Nature (1991) 6.20
GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli. Nature (1989) 5.15
Protein folding in mitochondria requires complex formation with hsp60 and ATP hydrolysis. Nature (1989) 4.57
Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfoleded state depends on two chaperonin proteins and Mg-ATP. Nature (1999) 4.57
A heat shock operon in Coxiella burnetti produces a major antigen homologous to a protein in both mycobacteria and Escherichia coli. J Bacteriol (1988) 3.06
GroE facilitates refolding of citrate synthase by suppressing aggregation. Biochemistry (1991) 2.92
Chaperonin-facilitated refolding of ribulosebisphosphate carboxylase and ATP hydrolysis by chaperonin 60 (groEL) are K+ dependent. Biochemistry (1990) 2.62
The universally conserved GroE (Hsp60) chaperonins. Annu Rev Microbiol (1991) 2.56
Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor. Nature (1989) 2.33
Sequential action of mitochondrial chaperones in protein import into the matrix. EMBO J (1991) 2.27
Chaperonin-mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity. EMBO J (1992) 2.20
Purification and properties of the groES morphogenetic protein of Escherichia coli. J Biol Chem (1986) 2.00
A major antigen from Mycobacterium tuberculosis which is homologous to the heat shock proteins groES from E. coli and the htpA gene product of Coxiella burneti. Nucleic Acids Res (1988) 1.96
Chaperonins facilitate the in vitro folding of monomeric mitochondrial rhodanese. J Biol Chem (1991) 1.92
Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring. J Biol Chem (1992) 1.59
Hydrolysis of adenosine 5'-triphosphate by Escherichia coli GroEL: effects of GroES and potassium ion. Biochemistry (1993) 1.47
Conformational states of ribulosebisphosphate carboxylase and their interaction with chaperonin 60. Biochemistry (1992) 1.38
The synthesis and purification of 2'-carboxy-D-arabinitol 1-phosphate, a natural inhibitor of ribulose 1,5-bisphosphate carboxylase, investigated by 31P n.m.r. Biochem J (1989) 1.21
Identification of a mammalian 10-kDa heat shock protein, a mitochondrial chaperonin 10 homologue essential for assisted folding of trimeric ornithine transcarbamoylase in vitro. Proc Natl Acad Sci U S A (1992) 1.19
Identification of a groES-like chaperonin in mitochondria that facilitates protein folding. Proc Natl Acad Sci U S A (1990) 1.18
Identification, characterization, and DNA sequence of a functional "double" groES-like chaperonin from chloroplasts of higher plants. Proc Natl Acad Sci U S A (1992) 1.11
The sites for catalysis and activation of ribulosebisphosphate carboxylase share a common domain. Arch Biochem Biophys (1986) 1.02
Cloning and characterization of the yeast chaperonin HSP60 gene. Gene (1989) 0.94
Large-scale preparation of ribulosebisphosphate carboxylase from a recombinant system in Escherichia coli characterized by extreme plasmid instability. Appl Environ Microbiol (1985) 0.92
Ribulosebisphosphate carboxylase/oxygenase from Rhodospirillum rubrum. Methods Enzymol (1982) 0.90
The complete primary structure of rat chaperonin 10 reveals a putative beta alpha beta nucleotide-binding domain with homology to p21ras. Biochim Biophys Acta (1993) 0.80
Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondria. J Biol Chem (1982) 12.07
The activation of ribulose-1,5-bisphosphate carboxylase by carbon dioxide and magnesium ions. Equilibria, kinetics, a suggested mechanism, and physiological implications. Biochemistry (1976) 9.91
Ribulose-1,5-bisphosphate carboxylase-oxygenase. Annu Rev Biochem (1983) 8.54
D-Ribulose-1,5-bisphosphate carboxylase-oxygenase. Improved methods for the activation and assay of catalytic activities. Anal Biochem (1977) 7.51
Two nuclear mutations that block mitochondrial protein import in yeast. Proc Natl Acad Sci U S A (1984) 7.39
Biogenesis of mitochondria. Annu Rev Cell Biol (1988) 6.96
Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria. Nature (1986) 5.58
Involvement of GTP-binding "G" proteins in transport through the Golgi stack. Cell (1987) 5.28
Import of proteins into mitochondria: precursor forms of the extramitochondrially made F1-ATPase subunits in yeast. Proc Natl Acad Sci U S A (1979) 5.21
Ribulose diphosphate oxygenase. I. Synthesis of phosphoglycolate by fraction-1 protein of leaves. Biochemistry (1973) 5.19
GroE heat-shock proteins promote assembly of foreign prokaryotic ribulose bisphosphate carboxylase oligomers in Escherichia coli. Nature (1989) 5.15
Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport. Proc Natl Acad Sci U S A (1988) 4.63
Reconstitution of active dimeric ribulose bisphosphate carboxylase from an unfoleded state depends on two chaperonin proteins and Mg-ATP. Nature (1999) 4.57
Role of an N-ethylmaleimide-sensitive transport component in promoting fusion of transport vesicles with cisternae of the Golgi stack. Cell (1988) 4.37
Import of proteins into mitochondria. Energy-dependent uptake of precursors by isolated mitochondria. J Biol Chem (1982) 4.25
Ribulose diphosphate oxygenase. II. Further proof of reaction products and mechanism of action. Biochemistry (1973) 4.19
Protein translocation across membranes. Science (1988) 4.12
A new type of coated vesicular carrier that appears not to contain clathrin: its possible role in protein transport within the Golgi stack. Cell (1986) 4.04
Properties of avian retrovirus particles defective in viral protease. J Virol (1990) 4.03
Interaction of sugar phosphates with the catalytic site of ribulose-1,5-bisphosphate carboxylase. Biochemistry (1981) 3.99
The amino-terminal region of an imported mitochondrial precursor polypeptide can direct cytoplasmic dihydrofolate reductase into the mitochondrial matrix. EMBO J (1984) 3.69
How are proteins imported into mitochondria? Cell (1983) 3.69
Vesicular transport between the endoplasmic reticulum and the Golgi stack requires the NEM-sensitive fusion protein. Nature (1989) 3.62
Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J (1999) 3.58
Cytochromes c1 and b2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism. Cell (1992) 3.42
Import of proteins into mitochondria. The precursor of cytochrome c1 is processed in two steps, one of them heme-dependent. J Biol Chem (1982) 3.26
Chaperonin-mediated protein folding. Annu Rev Biophys Biomol Struct (2001) 3.24
Fixation of O(2) during Photorespiration: Kinetic and Steady-State Studies of the Photorespiratory Carbon Oxidation Cycle with Intact Leaves and Isolated Chloroplasts of C(3) Plants. Plant Physiol (1978) 3.20
Sequential intermediates in the pathway of intercompartmental transport in a cell-free system. Cell (1984) 3.07
Carbamate formation on the epsilon-amino group of a lysyl residue as the basis for the activation of ribulosebisphosphate carboxylase by CO2 and Mg2+. Biochemistry (1980) 3.00
Determinants for glycophospholipid anchoring of the Saccharomyces cerevisiae GAS1 protein to the plasma membrane. Mol Cell Biol (1991) 2.96
A 70-kd protein of the yeast mitochondrial outer membrane is targeted and anchored via its extreme amino terminus. EMBO J (1984) 2.96
A chemically synthesized pre-sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers. EMBO J (1986) 2.91
Dynamics of the chaperonin ATPase cycle: implications for facilitated protein folding. Science (1994) 2.88
Import of proteins into mitochondria. Partial purification of a matrix-located protease involved in cleavage of mitochondrial precursor polypeptides. J Biol Chem (1983) 2.81
The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix. FEBS Lett (1984) 2.75
Dynamics of transitional endoplasmic reticulum sites in vertebrate cells. Mol Biol Cell (2000) 2.64
Chaperonin-facilitated refolding of ribulosebisphosphate carboxylase and ATP hydrolysis by chaperonin 60 (groEL) are K+ dependent. Biochemistry (1990) 2.62
Molecular chaperones and protein folding in plants. Plant Mol Biol (1996) 2.61
Golgi structure correlates with transitional endoplasmic reticulum organization in Pichia pastoris and Saccharomyces cerevisiae. J Cell Biol (1999) 2.60
A precursor protein partly translocated into yeast mitochondria is bound to a 70 kd mitochondrial stress protein. EMBO J (1990) 2.56
Possible role for fatty acyl-coenzyme A in intracellular protein transport. Nature (1987) 2.56
Yeast mitochondrial outer membrane specifically binds cytoplasmically-synthesized precursors of mitochondrial proteins. EMBO J (1983) 2.55
A role for actin, Cdc1p, and Myo2p in the inheritance of late Golgi elements in Saccharomyces cerevisiae. J Cell Biol (2001) 2.54
Cytochrome c oxidase from bakers' yeast. I. Isolation and properties. J Biol Chem (1973) 2.50
Isolation, identification, and synthesis of 2-carboxyarabinitol 1-phosphate, a diurnal regulator of ribulose-bisphosphate carboxylase activity. Proc Natl Acad Sci U S A (1987) 2.49
The outer membrane of yeast mitochondria: isolation of outside-out sealed vesicles. EMBO J (1983) 2.48
Import of proteins into mitochondria. Energy-dependent, two-step processing of the intermembrane space enzyme cytochrome b2 by isolated yeast mitochondria. J Biol Chem (1982) 2.46
Immunogenicity of hepatitis B Vaccines. Implications for persons at occupational risk of hepatitis B virus infection. Am J Prev Med (1998) 2.41
A monoclonal antibody against an activation epitope on mouse integrin chain beta 1 blocks adhesion of lymphocytes to the endothelial integrin alpha 6 beta 1. Proc Natl Acad Sci U S A (1993) 2.40
Imported mitochondrial proteins cytochrome b2 and cytochrome c1 are processed in two steps. Proc Natl Acad Sci U S A (1982) 2.39
Mitochondrial proteins essential for viability mediate protein import into yeast mitochondria. Nature (1991) 2.37
Import of proteins into mitochondria. Yeast cells grown in the presence of carbonyl cyanide m-chlorophenylhydrazone accumulate massive amounts of some mitochondrial precursor polypeptides. J Biol Chem (1982) 2.34
Import of proteins into mitochondria: a 70 kilodalton outer membrane protein with a large carboxy-terminal deletion is still transported to the outer membrane. EMBO J (1983) 2.33
Isolation of the nuclear yeast genes for citrate synthase and fifteen other mitochondrial proteins by a new screening method. EMBO J (1984) 2.33
Import of mitochondrial carriers mediated by essential proteins of the intermembrane space. Science (1998) 2.27
Sequential action of mitochondrial chaperones in protein import into the matrix. EMBO J (1991) 2.27
Cloning of the SNG1 gene of Arabidopsis reveals a role for a serine carboxypeptidase-like protein as an acyltransferase in secondary metabolism. Plant Cell (2000) 2.26
Heme is necessary for the accumulation and assembly of cytochrome c oxidase subunits in Saccharomyces cerevisiae. J Biol Chem (1978) 2.25
Protein import into yeast mitochondria is accelerated by the outer membrane protein MAS70. EMBO J (1990) 2.22
A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site. Nature (1989) 2.18
Mitochondrial presequences. J Biol Chem (1988) 2.18
The presequences of two imported mitochondrial proteins contain information for intracellular and intramitochondrial sorting. Cell (1986) 2.14
Energy-dependent processing of cytoplasmically made precursors to mitochondrial proteins. Proc Natl Acad Sci U S A (1979) 2.14
Import of proteins into mitochondria. Extramitochondrial pools and post-translational import of mitochondrial protein precursors in vivo. J Biol Chem (1982) 2.12
Reduced nicotinamide adenine dinucleotide-nitrate reductase of Chlorella vulgaris. Purification, prosthetic groups, and molecular properties. J Biol Chem (1975) 2.12
Artificial mitochondrial presequences. Proc Natl Acad Sci U S A (1986) 2.11
Both ATP and an energized inner membrane are required to import a purified precursor protein into mitochondria. EMBO J (1987) 2.08
The first twelve amino acids of a yeast mitochondrial outer membrane protein can direct a nuclear-coded cytochrome oxidase subunit to the mitochondrial inner membrane. EMBO J (1985) 2.06
Purification and characterization of the nickel-containing multicomponent urease from Klebsiella aerogenes. J Biol Chem (1987) 2.02
A yeast mutant lacking mitochondrial manganese-superoxide dismutase is hypersensitive to oxygen. Proc Natl Acad Sci U S A (1986) 2.01
A purified precursor polypeptide requires a cytosolic protein fraction for import into mitochondria. EMBO J (1984) 1.99
Protein import into mitochondria: ATP-dependent protein translocation activity in a submitochondrial fraction enriched in membrane contact sites and specific proteins. J Cell Biol (1989) 1.98
Subunit IV of yeast cytochrome c oxidase: cloning and nucleotide sequencing of the gene and partial amino acid sequencing of the mature protein. EMBO J (1984) 1.97
Import of proteins into mitochondria: nucleotide sequence of the gene for a 70-kd protein of the yeast mitochondrial outer membrane. EMBO J (1983) 1.97
MAS1, a gene essential for yeast mitochondrial assembly, encodes a subunit of the mitochondrial processing protease. EMBO J (1988) 1.95
DNA-protein conjugates can enter mitochondria via the protein import pathway. Nature (1989) 1.95
Head impulse test in unilateral vestibular loss: vestibulo-ocular reflex and catch-up saccades. Neurology (2008) 1.93
Amphiphilicity is essential for mitochondrial presequence function. EMBO J (1988) 1.93
Chaperonins facilitate the in vitro folding of monomeric mitochondrial rhodanese. J Biol Chem (1991) 1.92
Mas37p, a novel receptor subunit for protein import into mitochondria. J Cell Biol (1995) 1.89
A two-subunit cytochrome c oxidase (cytochrome aa3) from Paracoccus dentrificans. Proc Natl Acad Sci U S A (1980) 1.88
Mitochondria: a historical review. J Cell Biol (1981) 1.88
Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells. J Biol Chem (1988) 1.87
Dynamic interaction between Isp45 and mitochondrial hsp70 in the protein import system of the yeast mitochondrial inner membrane. Proc Natl Acad Sci U S A (1994) 1.87
Import of proteins into yeast mitochondria: the purified matrix processing protease contains two subunits which are encoded by the nuclear MAS1 and MAS2 genes. EMBO J (1988) 1.87
Mitochondrial assembly in respiration-deficient mutants of Saccharomyces cerevisiae. II. Effect of nuclear and extrachromosomal mutations on the formation of cytochrome c oxidase. J Biol Chem (1973) 1.85
Three-dimensional vector analysis of the human vestibuloocular reflex in response to high-acceleration head rotations. I. Responses in normal subjects. J Neurophysiol (1996) 1.85
ATP-dependent proteases that also chaperone protein biogenesis. Trends Biochem Sci (1997) 1.85
Import of proteins into mitochondria. Annu Rev Genet (1991) 1.84
Protein unfolding and the energetics of protein translocation across biological membranes. Cell (1988) 1.84
A chimeric mitochondrial precursor protein with internal disulfide bridges blocks import of authentic precursors into mitochondria and allows quantitation of import sites. J Cell Biol (1988) 1.83
Chaperonin function: folding by forced unfolding. Science (1999) 1.83
A yeast mitochondrial outer membrane protein essential for protein import and cell viability. Nature (1990) 1.82
A yeast t-SNARE involved in endocytosis. Mol Biol Cell (1998) 1.82
Requirement for the yeast gene LON in intramitochondrial proteolysis and maintenance of respiration. Science (1994) 1.82
Fatty acyl-coenzyme A is required for budding of transport vesicles from Golgi cisternae. Cell (1989) 1.81