Published in EMBO J on July 15, 1994
Exploring the DNA-binding specificities of zinc fingers with DNA microarrays. Proc Natl Acad Sci U S A (2001) 5.08
Selection of DNA binding sites for zinc fingers using rationally randomized DNA reveals coded interactions. Proc Natl Acad Sci U S A (1994) 4.12
Ultrahigh-throughput screening in drop-based microfluidics for directed evolution. Proc Natl Acad Sci U S A (2010) 3.72
Efficient construction of a large nonimmune phage antibody library: the production of high-affinity human single-chain antibodies to protein antigens. Proc Natl Acad Sci U S A (1998) 2.32
By-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selection. Nucleic Acids Res (2010) 1.87
A hierarchical approach to protein molecular evolution. Proc Natl Acad Sci U S A (1999) 1.80
The importance of being tyrosine: lessons in molecular recognition from minimalist synthetic binding proteins. ACS Chem Biol (2009) 1.65
scFv antibody: principles and clinical application. Clin Dev Immunol (2012) 1.64
Induction of human papillomavirus type 18 late gene expression and genomic amplification in organotypic cultures from transfected DNA templates. J Virol (1997) 1.59
Sequencing antibody repertoires: the next generation. MAbs (2011) 1.52
A novel strategy for generating monoclonal antibodies from single, isolated lymphocytes producing antibodies of defined specificities. Proc Natl Acad Sci U S A (1996) 1.45
CARbodies: Human Antibodies Against Cell Surface Tumor Antigens Selected From Repertoires Displayed on T Cell Chimeric Antigen Receptors. Mol Ther Nucleic Acids (2013) 1.45
Llama antibodies against a lactococcal protein located at the tip of the phage tail prevent phage infection. J Bacteriol (2005) 1.31
Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. J Neurosci (2008) 1.28
A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells. Proc Natl Acad Sci U S A (1996) 1.24
A convenient approach to the synthesis of trinucleotide phosphoramidites--synthons for the generation of oligonucleotide/peptide libraries. Nucleic Acids Res (1996) 1.19
A method for the generation of combinatorial antibody libraries using pIX phage display. Proc Natl Acad Sci U S A (2002) 1.18
Human autoantibody recognition of DNA. Proc Natl Acad Sci U S A (1995) 1.17
Synthetic antibody libraries focused towards peptide ligands. J Mol Biol (2008) 1.15
Using phage and yeast display to select hundreds of monoclonal antibodies: application to antigen 85, a tuberculosis biomarker. PLoS One (2012) 1.13
By-passing selection: direct screening for antibody-antigen interactions using protein arrays. Nucleic Acids Res (2000) 1.09
In vitro potency, pharmacokinetic profiles, and pharmacological activity of optimized anti-IL-21R antibodies in a mouse model of lupus. MAbs (2010) 1.09
A compact phage display human scFv library for selection of antibodies to a wide variety of antigens. BMC Biotechnol (2009) 1.08
CIS display: In vitro selection of peptides from libraries of protein-DNA complexes. Proc Natl Acad Sci U S A (2004) 1.07
On the influence of vector design on antibody phage display. J Biotechnol (2006) 1.07
High-level secretion of recombinant monomeric murine and human single-chain Fv antibodies from Drosophila S2 cells. Protein Eng Des Sel (2011) 1.06
Specific secretion of active single-chain Fv antibodies into the supernatants of Escherichia coli cultures by use of the hemolysin system. Appl Environ Microbiol (2000) 1.03
High-affinity recombinant phage antibodies to the pan-carcinoma marker epithelial glycoprotein-2 for tumour targeting. Br J Cancer (1998) 1.02
A method for directed evolution and functional cloning of enzymes. Proc Natl Acad Sci U S A (1998) 1.01
Use of a single-chain antibody library for ovarian cancer biomarker discovery. Mol Cell Proteomics (2010) 1.00
Eliminating helper phage from phage display. Nucleic Acids Res (2006) 0.99
Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus. PLoS One (2009) 0.98
Natural and man-made V-gene repertoires for antibody discovery. Front Immunol (2012) 0.98
Antibody engineering to develop new antirheumatic therapies. Arthritis Res Ther (2009) 0.97
An improved helper phage system for efficient isolation of specific antibody molecules in phage display. Nucleic Acids Res (2002) 0.97
Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization. Nat Biotechnol (2010) 0.97
Selection of functional human antibodies from retroviral display libraries. Nucleic Acids Res (2005) 0.97
The affinity-selection of a minibody polypeptide inhibitor of human interleukin-6. EMBO J (1994) 0.95
Generation, affinity maturation, and characterization of a human anti-human NKG2D monoclonal antibody with dual antagonistic and agonistic activity. J Mol Biol (2008) 0.94
The multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategies. J Biol Chem (2010) 0.94
Disruption of anthrax toxin binding with the use of human antibodies and competitive inhibitors. Infect Immun (1999) 0.94
Mining human antibody repertoires. MAbs (2010) 0.92
Recombinatorial cloning using heterologous lox sites. Genome Res (2004) 0.92
Selection of single chain variable fragments (scFv) against the glycoprotein antigen of the rabies virus from a human synthetic scFv phage display library and their fusion with the Fc region of human IgG1. Clin Exp Immunol (2001) 0.92
A novel heavy domain antibody library with functionally optimized complementarity determining regions. PLoS One (2013) 0.91
A strategy of exon shuffling for making large peptide repertoires displayed on filamentous bacteriophage. Proc Natl Acad Sci U S A (1996) 0.91
Accelerating phage-display library selection by reversible and site-specific biotinylation. Protein Eng Des Sel (2009) 0.90
Affinity-matured anti-glycoprotein NMB recombinant immunotoxins targeting malignant gliomas and melanomas. Int J Cancer (2010) 0.90
Routes to covalent catalysis by reactive selection for nascent protein nucleophiles. J Am Chem Soc (2007) 0.90
Direct selection of monoclonal phosphospecific antibodies without prior phosphoamino acid mapping. J Biol Chem (2009) 0.89
Identification of a GTP-bound Rho specific scFv molecular sensor by phage display selection. BMC Biotechnol (2008) 0.88
Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies. PLoS One (2008) 0.86
Basis for selection of improved carbohydrate-binding single-chain antibodies from synthetic gene libraries. Proc Natl Acad Sci U S A (1995) 0.85
A large semi-synthetic single-chain Fv phage display library based on chicken immunoglobulin genes. BMC Biotechnol (2004) 0.85
Reactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamics. Proc Natl Acad Sci U S A (2011) 0.84
Isolation of high-affinity single-chain antibodies against Mycobacterium avium subsp. paratuberculosis surface proteins from sheep with Johne's disease. Clin Vaccine Immunol (2006) 0.82
Targeting the active site of the placental isozyme of alkaline phosphatase by phage-displayed scFv antibodies selected by a specific uncompetitive inhibitor. BMC Biotechnol (2005) 0.82
The use of phage display to generate conformation-sensor recombinant antibodies. Nat Protoc (2012) 0.82
Human monomeric antibody fragments to TRAIL-R1 and TRAIL-R2 that display potent in vitro agonism. MAbs (2009) 0.82
A broad set of different llama antibodies specific for a 16 kDa heat shock protein of Mycobacterium tuberculosis. PLoS One (2011) 0.82
Phage display on the base of filamentous bacteriophages: application for recombinant antibodies selection. Acta Naturae (2009) 0.81
Selection of recombinant antibodies specific for pathogenic Streptococcus suis by subtractive phage display. Infect Immun (2000) 0.81
Oligonucleotide-assisted cleavage and ligation: a novel directional DNA cloning technology to capture cDNAs. Application in the construction of a human immune antibody phage-display library. Nucleic Acids Res (2005) 0.81
Isolation of scFv fragments specific for monokine induced by interferon-gamma (MIG) using phage display. J Immunol Methods (2010) 0.80
Deep sequencing in library selection projects: what insight does it bring? Curr Opin Struct Biol (2015) 0.80
Intrabody and Parkinson's disease. Biochim Biophys Acta (2008) 0.80
In vitro immunization of naive human B cells yields high affinity immunoglobulin G antibodies as illustrated by phage display. Immunology (1996) 0.80
Isolation of anti-angiogenesis antibodies from a large combinatorial repertoire by colony filter screening. Nucleic Acids Res (2001) 0.80
A novel synthetic naïve human antibody library allows the isolation of antibodies against a new epitope of oncofetal fibronectin. MAbs (2011) 0.80
A highly functional synthetic phage display library containing over 40 billion human antibody clones. PLoS One (2014) 0.80
Epsilon haemoglobin specific antibodies with applications in noninvasive prenatal diagnosis. J Biomed Biotechnol (2009) 0.79
Tapping diversity lost in transformations--in vitro amplification of ligation reactions. Nucleic Acids Res (2006) 0.79
Functional analysis of the CXXC motif using phage antibodies that cross-react with protein disulphide-isomerase family proteins. Biochem J (2004) 0.79
Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies. MAbs (2013) 0.79
Phage display-derived human antibodies in clinical development and therapy. MAbs (2016) 0.79
A simple luciferase assay for signal transduction activity detection of epidermal growth factor displayed on phage. Nucleic Acids Res (1997) 0.79
A human monoclonal antibody specific to placental alkaline phosphatase, a marker of ovarian cancer. MAbs (2014) 0.78
Human scFv antibody fragments specific for hepatocellular carcinoma selected from a phage display library. World J Gastroenterol (2005) 0.78
Selection of single-chain antibodies against the VP8* subunit of rotavirus VP4 outer capsid protein and their expression in Lactobacillus casei. Appl Environ Microbiol (2004) 0.77
Ligand-targeted theranostic nanomedicines against cancer. J Control Release (2016) 0.77
Production of recombinant antibodies using bacteriophages. Eur J Microbiol Immunol (Bp) (2014) 0.77
Two neutralizing human anti-RSV antibodies: cloning, expression, and characterization. Mol Med (1999) 0.77
Antibodies-antidotes against organophosphorus compounds. Dokl Biochem Biophys (2009) 0.77
Characterization and applications of Nanobodies against human procalcitonin selected from a novel naïve Nanobody phage display library. J Nanobiotechnology (2015) 0.77
Production and characterization of a human recombinant monoclonal Fab fragment specific for influenza A viruses. Clin Diagn Lab Immunol (2003) 0.77
Anti-non-Gal-specific combination treatment with an anti-idiotypic Ab and an inhibitory small molecule mitigates the xenoantibody response. Xenotransplantation (2014) 0.76
Antibodies against non-immunizing antigens derived from a large immune scFv library. Mol Cells (2011) 0.76
Degradation of C-terminal tag sequences on domain antibodies purified from E. coli supernatant. MAbs (2014) 0.76
An efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification. MAbs (2012) 0.76
Generation of “LYmph Node Derived Antibody Libraries” (LYNDAL) for selecting fully human antibody fragments with therapeutic potential. MAbs (2014) 0.76
Fluorescent T7 display phages obtained by translational frameshift. Nucleic Acids Res (2006) 0.76
Continuous affinity-based selection: rapid screening and simultaneous amplification of bacterial surface-display libraries. Biochem J (2001) 0.76
Covalent binding antibodies suppress advanced glycation: on the innate tier of adaptive immunity. Acta Naturae (2009) 0.75
Development of a Novel Human Single Chain Antibody Against EGFRVIII Antigen by Phage Display Technology. Adv Pharm Bull (2016) 0.75
Detection of TNT-derivatives with recombinant phages. Bacteriophage (2012) 0.75
Rapid isolation of a single-chain antibody against the cyanobacterial toxin microcystin-LR by phage display and its use in the immunoaffinity concentration of microcystins from water. Appl Environ Microbiol (2002) 0.75
A study of the mechanism of the chaperone-like function of an scFv of human creatine kinase by computer simulation. PLoS One (2013) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene (1985) 213.67
Production of single-stranded plasmid DNA. Methods Enzymol (1987) 39.38
High efficiency transformation of E. coli by high voltage electroporation. Nucleic Acids Res (1988) 34.78
Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene (1989) 23.74
Segregation of New Lysogenic Types during Growth of a Doubly Lysogenic Strain Derived from Escherichia Coli K12. Genetics (1954) 18.73
An Hsp70-like protein in the ER: identity with the 78 kd glucose-regulated protein and immunoglobulin heavy chain binding protein. Cell (1986) 10.38
Formation, induction, and curing of bacteriophage P1 lysogens. Virology (1972) 10.28
Heavy chain variable region contribution to the NPb family of antibodies: somatic mutation evident in a gamma 2a variable region. Cell (1981) 9.54
Phage antibodies: filamentous phage displaying antibody variable domains. Nature (1990) 8.67
Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites. J Mol Biol (1981) 8.02
By-passing immunization. Human antibodies from V-gene libraries displayed on phage. J Mol Biol (1991) 6.62
Canonical structures for the hypervariable regions of immunoglobulins. J Mol Biol (1987) 6.42
Assembly of combinatorial antibody libraries on phage surfaces: the gene III site. Proc Natl Acad Sci U S A (1991) 5.94
Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda. Science (1989) 5.73
Conformations of immunoglobulin hypervariable regions. Nature (1990) 5.31
Making antibodies by phage display technology. Annu Rev Immunol (1994) 5.04
P1 site-specific recombination: nucleotide sequence of the recombining sites. Proc Natl Acad Sci U S A (1982) 4.99
Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors. Anal Biochem (1991) 4.82
Making antibody fragments using phage display libraries. Nature (1991) 4.61
Somatic mutation and the maturation of immune response to 2-phenyl oxazolone. Nature (1984) 4.45
Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system. J Immunol Methods (1991) 4.34
Chemical and serological studies with an iodine-containing synthetic immunological determinant 4-hydroxy-3-iodo-5-nitrophenylacetic acid (NIP) and related compounds. Immunology (1966) 4.08
Direct clone characterization from plaques and colonies by the polymerase chain reaction. Nucleic Acids Res (1989) 3.98
Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucleic Acids Res (1991) 3.89
The role of the loxP spacer region in P1 site-specific recombination. Nucleic Acids Res (1986) 3.63
Purification of his-tagged proteins in non-denaturing conditions suggests a convenient method for protein interaction studies. Nucleic Acids Res (1991) 3.48
Kinetic maturation of an immune response. Nature (1991) 3.26
The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J Mol Biol (1992) 3.19
Recombinant human Fab fragments neutralize human type 1 immunodeficiency virus in vitro. Proc Natl Acad Sci U S A (1992) 2.98
"Diabodies": small bivalent and bispecific antibody fragments. Proc Natl Acad Sci U S A (1993) 2.91
Theoretical studies of clonal selection: minimal antibody repertoire size and reliability of self-non-self discrimination. J Theor Biol (1979) 2.58
Selection of phage antibodies by binding affinity. Mimicking affinity maturation. J Mol Biol (1992) 2.50
Clonal recruitment and somatic mutation in the generation of immunological memory to the hapten NP. EMBO J (1986) 2.35
Structure of primary anti-(4-hydroxy-3-nitrophenyl)acetyl (NP) antibodies in normal and idiotypically suppressed C57BL/6 mice. Eur J Immunol (1985) 2.22
Length distribution of CDRH3 in antibodies. Proteins (1993) 2.12
Human anti-self antibodies with high specificity from phage display libraries. EMBO J (1993) 2.08
Structural repertoire of the human VH segments. J Mol Biol (1992) 2.06
By-passing immunization: building high affinity human antibodies by chain shuffling. Biotechnology (N Y) (1992) 2.05
Antibody fragments from a 'single pot' phage display library as immunochemical reagents. EMBO J (1994) 2.02
Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system. J Biol Chem (1992) 1.95
Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem. Proc Natl Acad Sci U S A (1992) 1.93
By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro. J Mol Biol (1992) 1.79
Definition of the human immunoglobulin variable lambda (IGLV) gene subgroups. Eur J Immunol (1990) 1.75
The effect of antibody isotype and antigenic epitope density on the complement-fixing activity of immune complexes: a systematic study using chimaeric anti-NIP antibodies with human Fc regions. Clin Exp Immunol (1991) 1.68
Structure and expression of the human immunoglobulin lambda genes. J Exp Med (1990) 1.56
Inheritance of antibody specificity V. Anti-2-phenyloxazolone in the mouse. J Exp Med (1978) 1.55
Human monoclonal Fab fragments derived from a combinatorial library bind to respiratory syncytial virus F glycoprotein and neutralize infectivity. Proc Natl Acad Sci U S A (1992) 1.54
DETERMINATION OF ANTIBODY AFFINITY FOR HAPTENS AND ANTIGENS BY MEANS OF FLUORESCENCE QUENCHING. Methods Med Res (1964) 1.45
A directory of human germ-line V kappa segments reveals a strong bias in their usage. Eur J Immunol (1994) 1.44
Human antibody fragments specific for human blood group antigens from a phage display library. Biotechnology (N Y) (1993) 1.40
Combinatorial infection and in vivo recombination: a strategy for making large phage antibody repertoires. Nucleic Acids Res (1993) 1.40
A surface expression vector for antibody screening. Gene (1991) 1.36
Immobilization chemistries suitable for use in the BIAcore surface plasmon resonance detector. Anal Biochem (1992) 1.35
Human immunoglobulin VH and D segments on chromosomes 15q11.2 and 16p11.2. Hum Mol Genet (1994) 1.29
Analysis of macromolecular interactions using immobilized ligands. Anal Biochem (1992) 1.27
Selection of human anti-hapten antibodies from semisynthetic libraries. Gene (1993) 1.23
Mechanisms of ligand binding by monoclonal anti-fluorescyl antibodies. J Biol Chem (1982) 1.22
Partial elucidation of an anti-hapten repertoire in BALB/c mice: comparative characterization of several monoclonal anti-fluorescyl antibodies. Mol Immunol (1981) 1.18
Heavy-chain directed B-cell maturation: continuous clonal selection beginning at the pre-B cell stage. Immunol Today (1994) 1.13
Cloning and sequencing of human immunoglobulin V lambda gene segments. Eur J Immunol (1993) 1.13
Fab assembly and enrichment in a monovalent phage display system. Biotechnology (N Y) (1991) 0.96
Analysis of active antibody concentration. Separation of affinity and concentration parameters. J Immunol Methods (1993) 0.95
Comparative properties of monoclonal antibodies comprising a high-affinity anti-fluorescyl idiotype family. Mol Immunol (1985) 0.93
Tolerance and ways to break it. Ann N Y Acad Sci (1993) 0.92
Selective enhancement of the tumour necrotic activity of TNF alpha with monoclonal antibody. Br J Cancer (1992) 0.89
Regulated expression of foreign genes fused to lac: control by glucose levels in growth medium. Nucleic Acids Res (1990) 0.89
Antibodies biotinylated via sugar moieties. Methods Enzymol (1990) 0.85
Idiotypic cross-reactivity of low-affinity anti-fluorescyl monoclonal antibodies. Mol Immunol (1984) 0.83
Participation of the lytic replicon in bacteriophage P1 plasmid maintenance. J Bacteriol (1989) 0.82
Introduction of a fluorescent label into the carbohydrate moiety of glycoconjugates. Biochem Biophys Res Commun (1975) 0.82
Chemical basis for diversity in antibody specificity analysed by hapten binding to monoclonal anti-4-hydroxy-3-nitrophenacetyl (NP) immunoglobulins. Mol Immunol (1981) 0.81
Construction, characterization, and mutagenesis of an anti-fluorescein single chain antibody idiotype family. J Biol Chem (1992) 0.80
Linkage of low and high affinity anti-fluorescein idiotype families. Mol Immunol (1986) 0.79
Analysis of fMRI time-series revisited. Neuroimage (1995) 17.70
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 12.66
Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo. Dev Biol (2001) 10.32
Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell (1999) 9.84
Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli. Nature (1989) 5.23
A specific neural substrate for perceiving facial expressions of disgust. Nature (1997) 5.12
Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana. Genes Dev (1999) 4.35
Replacing the complementarity-determining regions in a human antibody with those from a mouse. Nature (1986) 4.19
Genquire: genome annotation browser/editor. Bioinformatics (2002) 4.17
Cloning immunoglobulin variable domains for expression by the polymerase chain reaction. Proc Natl Acad Sci U S A (1989) 3.99
Social intelligence in the normal and autistic brain: an fMRI study. Eur J Neurosci (1999) 3.94
Activation of auditory cortex during silent lipreading. Science (1997) 3.94
Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science (2001) 3.87
Mapping motor inhibition: conjunctive brain activations across different versions of go/no-go and stop tasks. Neuroimage (2001) 3.51
Evidence for cortical "disconnection" as a mechanism of age-related cognitive decline. Neurology (2001) 3.30
Non-invasive assessment of axonal fiber connectivity in the human brain via diffusion tensor MRI. Magn Reson Med (1999) 3.22
The amygdala theory of autism. Neurosci Biobehav Rev (2000) 3.19
Statistical methods of estimation and inference for functional MR image analysis. Magn Reson Med (1996) 3.13
Antibody arrays for high-throughput screening of antibody-antigen interactions. Nat Biotechnol (2000) 3.06
The functional neuroanatomy of social behaviour: changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain (2000) 3.03
Mapping auditory hallucinations in schizophrenia using functional magnetic resonance imaging. Arch Gen Psychiatry (2000) 2.93
Neural responses to facial and vocal expressions of fear and disgust. Proc Biol Sci (1998) 2.93
Cranial and cardiac neural crest defects in endothelin-A receptor-deficient mice. Development (1998) 2.92
Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: a study with functional MRI. Am J Psychiatry (1999) 2.72
ICK1, a cyclin-dependent protein kinase inhibitor from Arabidopsis thaliana interacts with both Cdc2a and CycD3, and its expression is induced by abscisic acid. Plant J (1998) 2.71
The human immunoglobulin VH repertoire. Immunol Today (1995) 2.60
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4. Science (1996) 2.56
Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene. Development (1998) 2.49
MSH2 deficient mice are viable and susceptible to lymphoid tumours. Nat Genet (1995) 2.49
APETALA1 and SEPALLATA3 interact to promote flower development. Plant J (2001) 2.33
Functional frontalisation with age: mapping neurodevelopmental trajectories with fMRI. Neurosci Biobehav Rev (2000) 2.31
Differential Regulation of beta-1,3-Glucanase Messenger RNAs in Response to Pathogen Infection. Plant Physiol (1991) 2.13
Human anti-self antibodies with high specificity from phage display libraries. EMBO J (1993) 2.08
Structural repertoire of the human VH segments. J Mol Biol (1992) 2.06
Role of Endothelin-1/Endothelin-A receptor-mediated signaling pathway in the aortic arch patterning in mice. J Clin Invest (1998) 2.04
Sequence of the human immunoglobulin diversity (D) segment locus: a systematic analysis provides no evidence for the use of DIR segments, inverted D segments, "minor" D segments or D-D recombination. J Mol Biol (1997) 2.03
Antibody fragments from a 'single pot' phage display library as immunochemical reagents. EMBO J (1994) 2.02
Methods for diagnosis and treatment of stimulus-correlated motion in generic brain activation studies using fMRI. Hum Brain Mapp (1999) 2.01
The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box protein required for normal patterning and growth in the floral meristem. Plant J (1999) 1.98
Diffusion tensor MRI assesses corticospinal tract damage in ALS. Neurology (1999) 1.98
Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells. Science (1989) 1.96
A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q. Nat Genet (1994) 1.81
Generic brain activation mapping in functional magnetic resonance imaging: a nonparametric approach. Magn Reson Imaging (1997) 1.78
Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3). J Clin Invest (2001) 1.78
The Arabidopsis BELL1 and KNOX TALE homeodomain proteins interact through a domain conserved between plants and animals. Plant Cell (2001) 1.77
Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. J Mol Biol (1999) 1.75
Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell (1998) 1.75
Cerebral correlates of preserved cognitive skills in autism: a functional MRI study of embedded figures task performance. Brain (1999) 1.75
Accelerated apoptosis in the Timp-3-deficient mammary gland. J Clin Invest (2001) 1.71
Normal-appearing white matter in ischemic leukoaraiosis: a diffusion tensor MRI study. Neurology (2001) 1.69
Conflicting MRI signals from gliosis and neuronal vacuolation in prion diseases. Neuroreport (1999) 1.68
Volumetric analysis reveals corticospinal tract degeneration and extramotor involvement in ALS. Neurology (2001) 1.68
Signaling pathways crucial for craniofacial development revealed by endothelin-A receptor-deficient mice. Dev Biol (2000) 1.65
In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells. Nucleic Acids Res (1992) 1.65
Salt-sensitive hypertension in endothelin-B receptor-deficient rats. J Clin Invest (2000) 1.65
A plant cyclin-dependent kinase inhibitor gene. Nature (1997) 1.65
Neurotoxic effects of gadopentetate dimeglumine: behavioral disturbance and morphology after intracerebroventricular injection in rats. AJNR Am J Neuroradiol (1996) 1.64
Serial precision of metabolite peak area ratios and water referenced metabolite peak areas in proton MR spectroscopy of the human brain. Magn Reson Imaging (1998) 1.63
Towards a functional neuroanatomy of self processing: effects of faces and words. Brain Res Cogn Brain Res (2000) 1.62
B- and T-cell markers in opsoclonus-myoclonus syndrome: immunophenotyping of CSF lymphocytes. Neurology (2004) 1.58
Transgenic expression of the endothelin-B receptor prevents congenital intestinal aganglionosis in a rat model of Hirschsprung disease. J Clin Invest (1998) 1.56
Characterization of events during the late stages of HPV16 infection in vivo using high-affinity synthetic Fabs to E4. Virology (1997) 1.56
Variable sensitivity of CCR5-tropic human immunodeficiency virus type 1 isolates to inhibition by RANTES analogs. J Virol (2000) 1.54
Pattern of neuronal activity associated with conscious and unconscious processing of visual signals. Proc Natl Acad Sci U S A (1997) 1.51
Design of a C/EBP-specific, dominant-negative bZIP protein with both inhibitory and gain-of-function properties. J Biol Chem (1996) 1.51
Patient-controlled analgesia in labour using remifentanil in two parturients with platelet abnormalities. Br J Anaesth (2000) 1.50
Distributed grey and white matter deficits in hyperkinetic disorder: MRI evidence for anatomical abnormality in an attentional network. Psychol Med (2001) 1.49
The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain. Mol Cell Biol (1997) 1.47
A directory of human germ-line V kappa segments reveals a strong bias in their usage. Eur J Immunol (1994) 1.44
Vaginal misoprostol enhances intrauterine insemination. Hum Reprod (2001) 1.43
The COP9 signalosome interacts with SCF UFO and participates in Arabidopsis flower development. Plant Cell (2003) 1.43
Role of adenosine deaminase in lymphocyte proliferation. Clin Exp Immunol (1976) 1.41
Time courses of left and right amygdalar responses to fearful facial expressions. Hum Brain Mapp (2001) 1.40
Inhibition of CCAAT/enhancer-binding protein alpha and beta translation by upstream open reading frames. J Biol Chem (1998) 1.40
Screening of phage antibody libraries. Methods Enzymol (1996) 1.39
Pseudomonas aeruginosa autoinducer modulates host cell responses through calcium signalling. Cell Microbiol (2006) 1.38
Neural correlates of formal thought disorder in schizophrenia: preliminary findings from a functional magnetic resonance imaging study. Arch Gen Psychiatry (2001) 1.38
Auditory hallucinations and the temporal cortical response to speech in schizophrenia: a functional magnetic resonance imaging study. Am J Psychiatry (1997) 1.38
Anaerobic induction of alanine aminotransferase in barley root tissue. Plant Physiol (1989) 1.37
Functional magnetic resonance image analysis of a large-scale neurocognitive network. Neuroimage (1996) 1.37
A differential neural response to threatening and non-threatening negative facial expressions in paranoid and non-paranoid schizophrenics. Psychiatry Res (1999) 1.36
Disruption of ECE-1 and ECE-2 reveals a role for endothelin-converting enzyme-2 in murine cardiac development. J Clin Invest (2000) 1.36
Differences in frontal cortical activation by a working memory task after substitution of risperidone for typical antipsychotic drugs in patients with schizophrenia. Proc Natl Acad Sci U S A (1999) 1.35
Common and distinct neural substrates for pragmatic, semantic, and syntactic processing of spoken sentences: an fMRI study. J Cogn Neurosci (2000) 1.35
Functional MRI study of the cognitive generation of affect. Am J Psychiatry (1999) 1.32
Characterization of white matter damage in ischemic leukoaraiosis with diffusion tensor MRI. Stroke (1999) 1.28
Somatic insertions and deletions shape the human antibody repertoire. J Mol Biol (1999) 1.28
Sequence and evolution of the human germline V lambda repertoire. J Mol Biol (1996) 1.27
Interaction of the virulence protein VirF of Agrobacterium tumefaciens with plant homologs of the yeast Skp1 protein. Curr Biol (2001) 1.27
The C/EBP bZIP domain can mediate lipopolysaccharide induction of the proinflammatory cytokines interleukin-6 and monocyte chemoattractant protein-1. J Biol Chem (2000) 1.26
A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts. Nucleic Acids Res (1986) 1.25
Human Fc gamma RI and Fc gamma RII interact with distinct but overlapping sites on human IgG. J Immunol (1991) 1.25
Quality control for functional magnetic resonance imaging using automated data analysis and Shewhart charting. Magn Reson Med (1999) 1.25
Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2. Hum Mol Genet (1995) 1.24
Redundancy of C/EBP alpha, -beta, and -delta in supporting the lipopolysaccharide-induced transcription of IL-6 and monocyte chemoattractant protein-1. J Immunol (1998) 1.23
Cortical processing of human somatic and visceral sensation. J Neurosci (2000) 1.22
A functional study of auditory verbal imagery. Psychol Med (2001) 1.21
The imprint of somatic hypermutation on the repertoire of human germline V genes. J Mol Biol (1996) 1.21
Quaternary structure changes in aspartate transcarbamylase studied by X-ray solution scattering. Signal transmission following effector binding. J Mol Biol (1985) 1.21