Published in Am J Physiol on March 01, 1994
Demonstration of an early and a late phase of ischemic preconditioning in mice. Am J Physiol (1998) 3.11
Sustained in vivo cardiac protection by a rationally designed peptide that causes epsilon protein kinase C translocation. Proc Natl Acad Sci U S A (1999) 2.44
Protein kinase C, an elusive therapeutic target? Nat Rev Drug Discov (2012) 2.33
Remote ischemic conditioning. J Am Coll Cardiol (2015) 1.66
Time-dependent and ethanol-induced cardiac protection from ischemia mediated by mitochondrial translocation of varepsilonPKC and activation of aldehyde dehydrogenase 2. J Mol Cell Cardiol (2008) 1.44
Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT. Am J Physiol Heart Circ Physiol (2008) 1.42
Mechanism of cardioprotection by early ischemic preconditioning. Cardiovasc Drugs Ther (2010) 1.41
Direct evidence that protein kinase C plays an essential role in the development of late preconditioning against myocardial stunning in conscious rabbits and that epsilon is the isoform involved. J Clin Invest (1998) 1.39
Retracted Microarray analysis for differentially expressed genes of patients undergoing total knee arthroplasty with ischemia preconditioning. J Orthop Surg Res (2014) 1.39
Aldehyde dehydrogenase 2 in cardiac protection: a new therapeutic target? Trends Cardiovasc Med (2009) 1.38
Formation of protein kinase C(epsilon)-Lck signaling modules confers cardioprotection. J Clin Invest (2002) 1.34
Cardioprotection from ischemia by a brief exposure to physiological levels of ethanol: role of epsilon protein kinase C. Proc Natl Acad Sci U S A (1999) 1.23
Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion. Cardiovasc Res (2009) 1.18
Massive palmitoylation-dependent endocytosis during reoxygenation of anoxic cardiac muscle. Elife (2013) 1.10
Preconditioning rabbit cardiomyocytes: role of pH, vacuolar proton ATPase, and apoptosis. J Clin Invest (1996) 1.09
Massive endocytosis triggered by surface membrane palmitoylation under mitochondrial control in BHK fibroblasts. Elife (2013) 1.02
Protein kinase C as a stress sensor. Cell Signal (2007) 1.00
Physiology of potassium channels in the inner membrane of mitochondria. Pflugers Arch (2011) 0.99
Activation of epsilon protein kinase C correlates with a cardioprotective effect of regular ethanol consumption. Proc Natl Acad Sci U S A (1998) 0.97
N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1. Am J Physiol Heart Circ Physiol (2008) 0.97
Postconditioning: a mechanical maneuver that triggers biological and molecular cardioprotective responses to reperfusion. Heart Fail Rev (2007) 0.94
Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling. J Biol Chem (2013) 0.92
Signalling pathways and mechanisms of protection in pre- and postconditioning: historical perspective and lessons for the future. Br J Pharmacol (2014) 0.90
Molecular Characterization of Reactive Oxygen Species in Myocardial Ischemia-Reperfusion Injury. Biomed Res Int (2015) 0.89
Getting to the heart of proteomics. N Engl J Med (2009) 0.88
A novel anti-diabetic drug, miglitol, markedly reduces myocardial infarct size in rabbits. Br J Pharmacol (1999) 0.88
JTV-519, a novel cardioprotective agent, improves the contractile recovery after ischaemia-reperfusion in coronary perfused guinea-pig ventricular muscles. Br J Pharmacol (2000) 0.87
Opening of mitochondrial K+ channels increases ischemic ATP levels by preventing hydrolysis. J Bioenerg Biomembr (2002) 0.85
Ischemic conditioning: the challenge of protecting the diabetic heart. Cardiovasc Diagn Ther (2014) 0.85
Hypoxia-regulated activity of PKCepsilon in the lens. Invest Ophthalmol Vis Sci (2008) 0.85
Sulprostone-induced reduction of myocardial infarct size in the rabbit by activation of ATP-sensitive potassium channels. Br J Pharmacol (1996) 0.85
Morphine and remifentanil-induced cardioprotection: its experimental and clinical outcomes. Korean J Anesthesiol (2011) 0.85
Modulation of cardiac interstitial noradrenaline levels through K(ATP) channels during ischemic preconditioning in rabbits: comparison of the effect of anesthesia between pentobarbital and ketamine + xylazine. Heart Vessels (1997) 0.84
Heat stress activates AKT via focal adhesion kinase-mediated pathway in neonatal rat ventricular myocytes. Am J Physiol Heart Circ Physiol (2008) 0.83
Blockade of the KATP-channel by glibenclamide aggravates ischemic injury, and counteracts ischemic preconditioning. Basic Res Cardiol (1997) 0.83
Differential modulation of unapposed connexin 43 hemichannel electrical conductance by protein kinase C isoforms. Pflugers Arch (2008) 0.83
Therapeutic potential of ischaemic preconditioning. Br J Clin Pharmacol (2000) 0.82
Ischemic preconditioning and heat shock activate Akt via a focal adhesion kinase-mediated pathway in Langendorff-perfused adult rat hearts. Am J Physiol Heart Circ Physiol (2009) 0.82
The kallikrein-kinin system as a regulator of cardiovascular and renal function. Compr Physiol (2011) 0.81
Transcriptional responses in the adaptation to ischaemia-reperfusion injury: a study of the effect of ischaemic preconditioning in total knee arthroplasty patients. J Transl Med (2010) 0.80
Suppression of reperfusion arrhythmia by ischemic preconditioning in the rat: is it mediated by the adenosine receptor, prostaglandin, or bradykinin receptor? Basic Res Cardiol (1995) 0.79
Impact of hypoglycemic agents on myocardial ischemic preconditioning. World J Diabetes (2014) 0.79
Ischaemic preconditioning protects against myocardial dysfunction caused by ischaemia in isolated hypertrophied rat hearts. Basic Res Cardiol (1997) 0.78
Monophosphoryl Lipid A: A Novel Agent for Inducing Pharmacologic Myocardial Preconditioning. J Thromb Thrombolysis (1996) 0.77
Pre-conditioning with low-level laser (light) therapy: light before the storm. Dose Response (2014) 0.77
Novel therapeutic strategies for ischemic heart disease. Pharmacol Res (2014) 0.77
Reactive oxygen species in early and delayed cardiac adaptation. Exp Clin Cardiol (2001) 0.76
Mast cell degranulation does not contribute to ischemic preconditioning in isolated rabbit hearts. Basic Res Cardiol (1997) 0.76
Ethanol for cardiac ischemia: the role of protein kinase c. Ther Adv Cardiovasc Dis (2008) 0.76
A comparison between ischemic preconditioning and anti-adrenergic interventions: cAMP, energy metabolism and functional recovery. Basic Res Cardiol (1996) 0.76
PRKCE gene encoding protein kinase C-epsilon-Dual roles at sarcomeres and mitochondria in cardiomyocytes. Gene (2016) 0.75
Preconditioning: markers vs. epiphenomena. Basic Res Cardiol (1996) 0.75
Role of Trimetazidine in Ischemic Preconditioning in Patients With Symptomatic Coronary Artery Disease. Medicine (Baltimore) (2015) 0.75
Kinase activity-independent anchoring function of protein kinase C-{delta}. Focus on "Protein kinase C-{delta} regulates the subcellular localization of Shc in H2O2-treated cardiomyocytes". Am J Physiol Cell Physiol (2010) 0.75
Role of protein kinase C in the reduction of infarct size by N-methyl-1-deoxynojirimycin, an alpha-1,6-glucosidase inhibitor. Br J Pharmacol (2001) 0.75
Protein kinase C-mediated sodium glucose transporter 1 activation in precondition-induced cardioprotection. Drug Des Devel Ther (2016) 0.75
Coronary vasoregulation in health and disease. Can J Cardiol (2007) 0.75
Regulation of cardiac excitability by protein kinase C isozymes. Front Biosci (Schol Ed) (2012) 0.75
O-linked beta-N-acetylglucosamine: a new piece of the cardioprotection puzzle? Circ Res (2009) 0.75
Effects and interaction, of cariporide and preconditioning on cardiac arrhythmias and infarction in rat in vivo. Br J Pharmacol (1999) 0.75
Effects of Bordetella pertussis toxin pretreatment on the antiarrhythmic action of ischaemic preconditioning in anaesthetized rats. Br J Pharmacol (1995) 0.75
Effects of anesthesia and K+ ATP channel blockade on interstitial adenosine accumulation in ischemic rabbit myocardium. Basic Res Cardiol (1996) 0.75
Does glycogen depletion play an important role in ischemic preconditioning? Heart Vessels (1997) 0.75
Regulation of ion channels in myocardial cells and protection of ischemic myocardium. Heart Fail Rev (2000) 0.75
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity (2000) 16.03
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science (1997) 13.61
Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Pharmacogenomics J (2001) 5.94
Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes. Biophys J (2001) 5.28
HuR regulates p21 mRNA stabilization by UV light. Mol Cell Biol (2000) 4.96
The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med (1993) 4.88
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci U S A (2001) 4.58
Diffusion of the Interspecies Electron Carriers H(2) and Formate in Methanogenic Ecosystems and Its Implications in the Measurement of K(m) for H(2) or Formate Uptake. Appl Environ Microbiol (1989) 4.53
The cpr5 mutant of Arabidopsis expresses both NPR1-dependent and NPR1-independent resistance. Plant Cell (1997) 4.47
Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity (2000) 4.44
Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol (2001) 4.39
Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart. Circulation (1991) 4.30
Visual identification of individual transfected cells for electrophysiology using antibody-coated beads. Biotechniques (1994) 4.24
Junction adhesion molecule is a receptor for reovirus. Cell (2001) 4.00
Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev (1998) 3.84
Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4. J Biol Chem (2000) 3.75
Role of nitric oxide in the vascular effects of local warming of the skin in humans. J Appl Physiol (1985) (1999) 3.65
Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. J Biol Chem (1996) 3.65
Timing of cyclin D1 expression within G1 phase is controlled by Rho. Nat Cell Biol (2001) 3.63
Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates. Proc Natl Acad Sci U S A (1997) 3.59
Response regulator output in bacterial chemotaxis. EMBO J (1998) 3.40
Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY. Cell (1997) 3.32
Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors. Mol Ther (2000) 3.32
Blocker protection in the pore of a voltage-gated K+ channel and its structural implications. Nature (2000) 3.26
Proto-oncogene PML controls genes devoted to MHC class I antigen presentation. Nature (1998) 3.22
Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals. Circ Res (2000) 3.19
Subsequent pulmonary embolism: risk after a negative helical CT pulmonary angiogram--prospective comparison with scintigraphy. Radiology (2000) 3.06
IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J (1998) 2.99
Activation of a mitogen-activated protein kinase pathway is involved in disease resistance in tobacco. Proc Natl Acad Sci U S A (2001) 2.98
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest (1997) 2.93
Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles. J Virol (1997) 2.91
Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA export. EMBO J (1998) 2.90
Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem (2000) 2.89
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene (2012) 2.82
Structure of the adenylyl cyclase catalytic core. Nature (1997) 2.81
Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock. Proc Natl Acad Sci U S A (2001) 2.77
Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J Cell Biol (2001) 2.73
Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells. J Neurochem (2000) 2.71
The regulation of reactive oxygen species production during programmed cell death. J Cell Biol (1998) 2.62
The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells. J Cell Sci (1998) 2.58
The C termini of Arabidopsis cryptochromes mediate a constitutive light response. Cell (2000) 2.53
Nitric oxide and cutaneous active vasodilation during heat stress in humans. J Appl Physiol (1985) (1998) 2.53
The cellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem J (1998) 2.50
Uncoupling PR gene expression from NPR1 and bacterial resistance: characterization of the dominant Arabidopsis cpr6-1 mutant. Plant Cell (1998) 2.48
On the use of thiol-modifying agents to determine channel topology. Neuropharmacology (1996) 2.47
Increased thermal stability of proteins in the presence of naturally occurring osmolytes. Biochemistry (1992) 2.47
Zinc inhibition of mitochondrial aconitase and its importance in citrate metabolism of prostate epithelial cells. J Biol Chem (1997) 2.47
Profiling serine hydrolase activities in complex proteomes. Biochemistry (2001) 2.46
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene (2012) 2.41
A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis. Neurology (2011) 2.39
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
Establishment, maintenance and description of cell lines from the tick Ixodes scapularis. J Parasitol (1994) 2.36
Design of allele-specific inhibitors to probe protein kinase signaling. Curr Biol (1998) 2.36
Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene. Neuron (1997) 2.34
Ischaemic preconditioning: can the protection be bottled? Lancet (1993) 2.33
The transcriptome of the arbuscular mycorrhizal fungus Glomus intraradices (DAOM 197198) reveals functional tradeoffs in an obligate symbiont. New Phytol (2011) 2.29
Ischemic preconditioning: from adenosine receptor to KATP channel. Annu Rev Physiol (2000) 2.28
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway. Genes Dev (1997) 2.26
Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China. Ann Neurol (1993) 2.23
Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures. J Cell Biol (2001) 2.23
Odd-parity superconductivity in Sr2RuO4. Science (2004) 2.22
Systemic gene expression after intravenous DNA delivery into adult mice. Science (1993) 2.21
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci U S A (2001) 2.21
Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. EMBO J (2001) 2.19
Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity (1999) 2.18
Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic window. Stroke (2001) 2.16
Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium. J Mol Cell Cardiol (1997) 2.15
Characterization of apelin, the ligand for the APJ receptor. J Neurochem (2000) 2.11
Intravenous pretreatment with A1-selective adenosine analogues protects the heart against infarction. Circulation (1992) 2.08
Dissecting glycoprotein quality control in the secretory pathway. Trends Biochem Sci (2001) 2.08
Method for obtaining structure and interactions from oriented lipid bilayers. Phys Rev E Stat Nonlin Soft Matter Phys (2000) 2.08
Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases. Proc Natl Acad Sci U S A (1994) 2.07
PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. J Cell Biol (2000) 2.07
Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease. J Intern Med (2014) 2.06
Identification of a global repressor gene, rsmA, of Erwinia carotovora subsp. carotovora that controls extracellular enzymes, N-(3-oxohexanoyl)-L-homoserine lactone, and pathogenicity in soft-rotting Erwinia spp. J Bacteriol (1995) 2.06
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol Cell Biol (2000) 2.06
Discovery of a receptor related to the galanin receptors. FEBS Lett (1999) 2.01
Xanthine oxidase as a source of free radical damage in myocardial ischemia. J Mol Cell Cardiol (1985) 2.00
Cloning and functional expression of two families of beta-subunits of the large conductance calcium-activated K+ channel. J Biol Chem (2000) 1.99
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice. Carcinogenesis (2001) 1.99
Unnatural ligands for engineered proteins: new tools for chemical genetics. Annu Rev Biophys Biomol Struct (2000) 1.99
Investigating the hows and whys of DNA endoreduplication. J Exp Bot (2001) 1.97
Human hair follicle bulge cells are biochemically distinct and possess an epithelial stem cell phenotype. J Investig Dermatol Symp Proc (1999) 1.96
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
Programmed myocyte cell death affects the viable myocardium after infarction in rats. Exp Cell Res (1996) 1.95
Inactivation of rsmA leads to overproduction of extracellular pectinases, cellulases, and proteases in Erwinia carotovora subsp. carotovora in the absence of the starvation/cell density-sensing signal, N-(3-oxohexanoyl)-L-homoserine lactone. Appl Environ Microbiol (1995) 1.94
Exaggerated heart rate oscillations during two meditation techniques. Int J Cardiol (1999) 1.93
A receptor for interleukin 10 is related to interferon receptors. Proc Natl Acad Sci U S A (1993) 1.91
microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity. Br J Cancer (2010) 1.90
Response of MG63 osteoblast-like cells to titanium and titanium alloy is dependent on surface roughness and composition. Biomaterials (1998) 1.89
Malignant peritoneal mesothelioma-Results from the International Expanded Access Program using pemetrexed alone or in combination with a platinum agent. Lung Cancer (2008) 1.88
Structure of human chorionic gonadotropin at 2.6 A resolution from MAD analysis of the selenomethionyl protein. Structure (1994) 1.87
Breast-cancer diagnosis with nipple fluid bFGF. Lancet (2000) 1.86
Evidence for a zinc uptake transporter in human prostate cancer cells which is regulated by prolactin and testosterone. J Biol Chem (1999) 1.86
Inactivation of the winged helix transcription factor HNF3alpha affects glucose homeostasis and islet glucagon gene expression in vivo. Genes Dev (1999) 1.86
Fruiting body production in Basidiomycetes. Appl Microbiol Biotechnol (2000) 1.83
Synaptic vesicle transporter expression regulates vesicle phenotype and quantal size. J Neurosci (2000) 1.81
A DEAD-box-family protein is required for nucleocytoplasmic transport of yeast mRNA. Mol Cell Biol (1996) 1.79