Published in Biochem J on July 15, 1998
tRNA cleavage is a conserved response to oxidative stress in eukaryotes. RNA (2008) 3.39
Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. J Clin Invest (1999) 3.30
Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress. Mol Cell Biol (2001) 2.08
Hypoxia and oxidative stress in breast cancer. Oxidative stress: its effects on the growth, metastatic potential and response to therapy of breast cancer. Breast Cancer Res (2001) 1.97
Repression of gene expression by oxidative stress. Biochem J (1999) 1.85
Contribution of mitochondrial GSH transport to matrix GSH status and colonic epithelial cell apoptosis. Free Radic Biol Med (2007) 1.81
Glomerular angiotensinogen is induced in mesangial cells in diabetic rats via reactive oxygen species--ERK/JNK pathways. Hypertens Res (2010) 1.71
Cisplatin-induced apoptosis in human malignant testicular germ cell lines depends on MEK/ERK activation. Br J Cancer (2004) 1.68
Cell death pathways in photodynamic therapy of cancer. Cancers (Basel) (2011) 1.45
Essential roles of receptor-interacting protein and TRAF2 in oxidative stress-induced cell death. Mol Cell Biol (2004) 1.43
ERK activation promotes neuronal degeneration predominantly through plasma membrane damage and independently of caspase-3. J Cell Biol (2004) 1.38
Redox regulation of epidermal growth factor receptor signaling through cysteine oxidation. Biochemistry (2012) 1.35
Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency. PLoS Pathog (2011) 1.27
Signal transduction pathways involved in oxidative stress-induced intestinal epithelial cell apoptosis. Pediatr Res (2005) 1.23
An evolutionarily conserved Rit GTPase-p38 MAPK signaling pathway mediates oxidative stress resistance. Mol Biol Cell (2011) 1.22
Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. BMC Ophthalmol (2003) 1.21
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells. Nat Chem Biol (2012) 1.15
Sulfur mustard analog induces oxidative stress and activates signaling cascades in the skin of SKH-1 hairless mice. Free Radic Biol Med (2009) 1.15
Aldose reductase, oxidative stress, and diabetic mellitus. Front Pharmacol (2012) 1.10
Effect of simultaneous inhibition of TNF-alpha production and xanthine oxidase in experimental acute pancreatitis: the role of mitogen activated protein kinases. Ann Surg (2004) 1.08
Caveolin-induced activation of the phosphatidylinositol 3-kinase/Akt pathway increases arsenite cytotoxicity. Mol Cell Biol (2003) 1.07
Cellular localization and functional significance of CYP3A4 in the human epileptic brain. Epilepsia (2011) 1.07
Gab1 is an integrator of cell death versus cell survival signals in oxidative stress. Mol Cell Biol (2003) 1.07
H2S donor, S-propargyl-cysteine, increases CSE in SGC-7901 and cancer-induced mice: evidence for a novel anti-cancer effect of endogenous H2S? PLoS One (2011) 1.05
p38-mediated regulation of an Fas-associated death domain protein-independent pathway leading to caspase-8 activation during TGFbeta-induced apoptosis in human Burkitt lymphoma B cells BL41. Mol Biol Cell (2001) 1.05
MnSOD in oxidative stress response-potential regulation via mitochondrial protein influx. Antioxid Redox Signal (2013) 1.04
Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stress. Mol Cell Biol (2007) 1.03
Redox regulation of protein kinases. Crit Rev Biochem Mol Biol (2013) 1.03
Manganese superoxide dismutase: guardian of the powerhouse. Int J Mol Sci (2011) 1.02
Redox regulation of FoxO transcription factors. Redox Biol (2015) 1.01
Driving cellular plasticity and survival through the signal transduction pathways of metabotropic glutamate receptors. Curr Neurovasc Res (2005) 1.01
Apoptosis induction by oxidized glycated LDL in human retinal capillary pericytes is independent of activation of MAPK signaling pathways. Mol Vis (2009) 1.01
The cytoprotective effect of N-acetyl-L-cysteine against ROS-induced cytotoxicity is independent of its ability to enhance glutathione synthesis. Toxicol Sci (2010) 1.01
Negative regulation of human U6 snRNA promoter by p38 kinase through Oct-1. Gene (2012) 0.99
Reactive nitrogen species-induced cell death requires Fas-dependent activation of c-Jun N-terminal kinase. Mol Cell Biol (2004) 0.99
New insights into the role of oxidative stress in scleroderma fibrosis. Open Rheumatol J (2012) 0.99
Dynamics of H2O2 availability to ARPE-19 cultures in models of oxidative stress. Free Radic Biol Med (2010) 0.97
Role of protein phosphatases and mitochondria in the neuroprotective effects of estrogens. Front Neuroendocrinol (2009) 0.96
Cooperative induction of CXCL10 involves NADPH oxidase: Implications for HIV dementia. Glia (2010) 0.96
Enhanced H(2)O(2)-induced cytotoxicity in "epithelioid" smooth muscle cells: implications for neointimal regression. Arterioscler Thromb Vasc Biol (2000) 0.95
The role of GSH efflux in staurosporine-induced apoptosis in colonic epithelial cells. Biochem Pharmacol (2008) 0.94
Cross-talk between signalling pathways and the multidrug resistant protein MDR-1. Br J Cancer (2001) 0.94
DPP4 deficiency exerts protective effect against H2O2 induced oxidative stress in isolated cardiomyocytes. PLoS One (2013) 0.93
RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells. Ann N Y Acad Sci (2010) 0.93
Molecular regulation of NADPH oxidase 5 via the MAPK pathway. Am J Physiol Heart Circ Physiol (2011) 0.93
HIV neuropathogenesis: a tight rope walk of innate immunity. J Neuroimmune Pharmacol (2010) 0.92
HIF1A induces expression of the WASF3 metastasis-associated gene under hypoxic conditions. Int J Cancer (2012) 0.92
Nrf2 and cardiovascular defense. Oxid Med Cell Longev (2013) 0.91
Hypoxia regulates insulin receptor substrate-2 expression to promote breast carcinoma cell survival and invasion. Cancer Res (2009) 0.91
Age-dependent changes in cell proliferation and cell death in the periodontal tissue and the submandibular gland in mice: a comparison with other tissues and organs. J Mol Histol (2007) 0.90
Hydrogen peroxide-induced Akt phosphorylation regulates Bax activation. Biochimie (2009) 0.90
Cardioprotection by polysaccharide sulfate against ischemia/reperfusion injury in isolated rat hearts. Acta Pharmacol Sin (2008) 0.90
Clinical experience with intravenous administration of ascorbic acid: achievable levels in blood for different states of inflammation and disease in cancer patients. J Transl Med (2013) 0.90
Gamma-oryzanol rich fraction regulates the expression of antioxidant and oxidative stress related genes in stressed rat's liver. Nutr Metab (Lond) (2010) 0.89
Preservation of cellular glutathione status and mitochondrial membrane potential by N-acetylcysteine and insulin sensitizers prevent carbonyl stress-induced human brain endothelial cell apoptosis. Curr Neurovasc Res (2009) 0.89
Identification of a protective role for protein phosphatase 1cgamma1 against oxidative stress-induced vascular smooth muscle cell apoptosis. J Biol Chem (2008) 0.88
Chikusetsu saponin IVa confers cardioprotection via SIRT1/ERK1/2 and Homer1a pathway. Sci Rep (2015) 0.88
Protective effect of canolol from oxidative stress-induced cell damage in ARPE-19 cells via an ERK mediated antioxidative pathway. Mol Vis (2011) 0.87
Watching the watcher: regulation of p53 by mitochondria. Future Oncol (2009) 0.85
Pharmacological and toxicological effects of co-exposure of human gingival fibroblasts to silver nanoparticles and sodium fluoride. Int J Nanomedicine (2014) 0.85
Phosphoinositide 3-kinase-dependent Ras activation by tauroursodesoxycholate in rat liver. Biochem J (2000) 0.84
Curbing cancer's sweet tooth: is there a role for MnSOD in regulation of the Warburg effect? Mitochondrion (2012) 0.84
Bornyl caffeate induces apoptosis in human breast cancer MCF-7 cells via the ROS- and JNK-mediated pathways. Acta Pharmacol Sin (2013) 0.83
The apoptotic volume decrease is an upstream event of MAP kinase activation during Staurosporine-induced apoptosis in HeLa cells. Int J Mol Sci (2012) 0.83
Bmi1 regulates auditory hair cell survival by maintaining redox balance. Cell Death Dis (2015) 0.83
Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: role of CYP2E1 and TNF-alpha and activation of JNK and P38 MAP kinase. Free Radic Biol Med (2009) 0.82
The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells. J Neurochem (2009) 0.82
Synergistic Activity of Carfilzomib and Panobinostat in Multiple Myeloma Cells via Modulation of ROS Generation and ERK1/2. Biomed Res Int (2015) 0.82
Differential effect of vinorelbine versus paclitaxel on ERK2 kinase activity during apoptosis in MCF-7 cells. Br J Cancer (2001) 0.81
The adaptor protein SH2B1β reduces hydrogen peroxide-induced cell death in PC12 cells and hippocampal neurons. J Mol Signal (2010) 0.80
Region- or state-related differences in expression and activation of extracellular signal-regulated kinases (ERKs) in naïve and pain-experiencing rats. BMC Neurosci (2007) 0.80
The INK4a /ARF locus: role in cell cycle control for renal cell epithelial tumor growth after the Chernobyl accident. Virchows Arch (2004) 0.80
Role of the ERK pathway for oxidant-induced parthanatos in human lymphocytes. PLoS One (2014) 0.80
NADPH oxidase 4 is required for interleukin-1β-mediated activation of protein kinase Cδ and downstream activation of c-jun N-terminal kinase signaling in smooth muscle. Free Radic Biol Med (2012) 0.79
Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress. Mol Cell Biol (2013) 0.79
Scolopendra subspinipes mutilans protected the cerulein-induced acute pancreatitis by inhibiting high-mobility group box protein-1. World J Gastroenterol (2013) 0.79
The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells. Toxicol Sci (2010) 0.79
Oryeongsan inhibits LPS-induced production of inflammatory mediators via blockade of the NF-kappaB, MAPK pathways and leads to HO-1 induction in macrophage cells. BMC Complement Altern Med (2014) 0.79
Reactive oxygen species regulate the generation of urokinase plasminogen activator in human hepatoma cells via MAPK pathways after treatment with hepatocyte growth factor. Exp Mol Med (2009) 0.78
Effects of nanotoxicity on female reproductivity and fetal development in animal models. Int J Mol Sci (2013) 0.78
Mitochondrial Ferritin Deletion Exacerbates β-Amyloid-Induced Neurotoxicity in Mice. Oxid Med Cell Longev (2017) 0.78
Effects of jnk inhibitor on inflammation and fibrosis in the ovary tissue of a rat model of polycystic ovary syndrome. Int J Clin Exp Pathol (2015) 0.77
Alteration of constitutive apoptosis in neutrophils by quinolones. Inflammation (2003) 0.77
Effect of hyperketonemia (Acetoacetate) on nuclear factor-κB and p38 mitogen-activated protein kinase activation mediated intercellular adhesion molecule 1 upregulation in endothelial cells. Metab Syndr Relat Disord (2014) 0.77
Doxorubicin and vinorelbine act independently via p53 expression and p38 activation respectively in breast cancer cell lines. Br J Cancer (2003) 0.77
Synergistic effects of nimesulide and 5-fluorouracil on tumor growth and apoptosis in the implanted hepatoma in mice. World J Gastroenterol (2003) 0.77
Heat-shock protein 90 alpha (HSP90α) modulates signaling pathways towards tolerance of oxidative stress and enhanced survival of hepatocytes of Mugil cephalus. Cell Stress Chaperones (2011) 0.76
Induction of apoptosis with diallyl disulfide in AGS gastric cancer cell line. J Korean Surg Soc (2011) 0.76
Effect of dihydrotestosterone on mouse embryonic stem cells exposed to H2O2-induced oxidative stress. J Vet Sci (2008) 0.76
Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One (2014) 0.76
Antioxidant and Hepatoprotective Effects of Procyanidins from Wild Grape (Vitis amurensis) Seeds in Ethanol-Induced Cells and Rats. Int J Mol Sci (2016) 0.76
Nicotine-Induced Apoptosis in Human Renal Proximal Tubular Epithelial Cells. PLoS One (2016) 0.76
Csk-Induced Phosphorylation of Src at Tyrosine 530 is Essential for H2O2-Mediated Suppression of ERK1/2 in Human Umbilical Vein Endothelial Cells. Sci Rep (2015) 0.75
Thymus vulgaris alleviates UVB irradiation induced skin damage via inhibition of MAPK/AP-1 and activation of Nrf2-ARE antioxidant system. J Cell Mol Med (2016) 0.75
Sabotaging of the oxidative stress response by an oncogenic noncoding RNA. FASEB J (2016) 0.75
Growth Hormone Deteriorates the Functional Outcome in an Experimental Model of Huntington's Disease Induced by 3-Nitropionic Acid. J Mov Disord (2013) 0.75
The Ethanol Extract from Lonicera japonica Thunb. Regresses Nonalcoholic Steatohepatitis in a Methionine- and Choline-Deficient Diet-Fed Animal Model. Nutrients (2015) 0.75
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells. Nucleic Acids Res (1989) 22.73
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science (1995) 17.76
Function and activation of NF-kappa B in the immune system. Annu Rev Immunol (1994) 17.04
Suppression of TNF-alpha-induced apoptosis by NF-kappaB. Science (1996) 12.23
A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc Natl Acad Sci U S A (1995) 10.25
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death. Cell (1996) 9.68
Mitogen-activated protein kinase pathways. Curr Opin Cell Biol (1997) 9.10
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins. Cell (1994) 8.52
Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis. Nature (1996) 6.75
MAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1. Nature (1997) 6.53
Features of apoptotic cells measured by flow cytometry. Cytometry (1992) 6.45
Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun. Nature (1995) 6.20
Molecular thanatopsis: a discourse on the BCL2 family and cell death. Blood (1996) 5.13
Daxx, a novel Fas-binding protein that activates JNK and apoptosis. Cell (1997) 4.39
MAPKs: new JNK expands the group. Trends Biochem Sci (1994) 4.10
H2O2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor. EMBO J (1993) 3.94
Activation of the IkappaB alpha kinase complex by MEKK1, a kinase of the JNK pathway. Cell (1997) 3.91
Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast. Curr Opin Cell Biol (1995) 3.79
Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. J Biol Chem (1996) 3.65
The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and gamma radiation. Duration of JNK activation may determine cell death and proliferation. J Biol Chem (1996) 3.38
Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3. Nature (1997) 2.46
Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. J Clin Invest (1997) 2.44
Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells. Circ Res (1997) 2.27
The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platinum, UV irradiation or heat. Curr Biol (1996) 2.18
Persistent activation of c-Jun N-terminal kinase 1 (JNK1) in gamma radiation-induced apoptosis. J Biol Chem (1996) 2.12
The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation. Proc Natl Acad Sci U S A (1995) 2.10
Regulation of apoptosis by bcl-2 family proteins and its role in cancer and chemoresistance. Curr Opin Oncol (1995) 2.04
Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells. J Biol Chem (1997) 2.02
IkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase. EMBO J (1997) 1.91
Activate NF-kappa B or die? Curr Biol (1997) 1.85
Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase. J Biol Chem (1997) 1.81
Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptor. Cancer Res (1996) 1.62
p27Kip1 overexpression causes apoptotic death of mammalian cells. Oncogene (1997) 1.57
Activation of the JNK pathway is essential for transformation by the Met oncogene. EMBO J (1997) 1.55
Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. J Biol Chem (1997) 1.51
Mitogen-activated protein kinase-mediated Fas apoptotic signaling pathway. Proc Natl Acad Sci U S A (1997) 1.47
Interaction between c-Rel and the mitogen-activated protein kinase kinase kinase 1 signaling cascade in mediating kappaB enhancer activation. J Biol Chem (1996) 1.45
MEK kinase is involved in tumor necrosis factor alpha-induced NF-kappaB activation and degradation of IkappaB-alpha. J Biol Chem (1996) 1.45
Lack of a role for Jun kinase and AP-1 in Fas-induced apoptosis. Mol Cell Biol (1997) 1.42
Regulation of stress-induced cytokine production by pyridinylimidazoles; inhibition of CSBP kinase. Bioorg Med Chem (1997) 1.31
Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes. Proc Natl Acad Sci U S A (1996) 1.19
Activation of c-Jun N-terminal kinase antagonizes an anti-apoptotic action of Bcl-2. J Biol Chem (1997) 1.14
Constitutively activated JNK is associated with HTLV-1 mediated tumorigenesis. Oncogene (1996) 1.12
Nuclear factor-kappaB is activated by hyperoxia but does not protect from cell death. J Biol Chem (1997) 1.01
Mitogen-activated protein kinase (MAPK) activation by butylated hydroxytoluene hydroperoxide: implications for cellular survival and tumor promotion. Cancer Res (1996) 1.00
Oxidants, oxidative stress and the biology of ageing. Nature (2000) 23.21
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity (2000) 16.03
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science (1997) 13.61
Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol (2001) 8.03
Integrating genotype and phenotype information: an overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Pharmacogenomics J (2001) 5.94
Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocr Rev (1984) 5.36
Reliable and global measurement of fluorescence resonance energy transfer using fluorescence microscopes. Biophys J (2001) 5.28
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents. Mol Cell Biol (1989) 5.25
HuR regulates p21 mRNA stabilization by UV light. Mol Cell Biol (2000) 4.96
The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med (1993) 4.88
Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I. Cell (1987) 4.76
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. Proc Natl Acad Sci U S A (2001) 4.58
Diffusion of the Interspecies Electron Carriers H(2) and Formate in Methanogenic Ecosystems and Its Implications in the Measurement of K(m) for H(2) or Formate Uptake. Appl Environ Microbiol (1989) 4.53
The cpr5 mutant of Arabidopsis expresses both NPR1-dependent and NPR1-independent resistance. Plant Cell (1997) 4.47
Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules. Immunity (2000) 4.44
Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis. Am J Pathol (2001) 4.39
Visual identification of individual transfected cells for electrophysiology using antibody-coated beads. Biotechniques (1994) 4.24
Junction adhesion molecule is a receptor for reovirus. Cell (2001) 4.00
Modification of yeast Cdc53p by the ubiquitin-related protein rub1p affects function of the SCFCdc4 complex. Genes Dev (1998) 3.84
Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4. J Biol Chem (2000) 3.75
Role of nitric oxide in the vascular effects of local warming of the skin in humans. J Appl Physiol (1985) (1999) 3.65
Activation of mitogen-activated protein kinase by H2O2. Role in cell survival following oxidant injury. J Biol Chem (1996) 3.65
Timing of cyclin D1 expression within G1 phase is controlled by Rho. Nat Cell Biol (2001) 3.63
Engineering unnatural nucleotide specificity for Rous sarcoma virus tyrosine kinase to uniquely label its direct substrates. Proc Natl Acad Sci U S A (1997) 3.59
Response regulator output in bacterial chemotaxis. EMBO J (1998) 3.40
Alternative initiation of translation and time-specific phosphorylation yield multiple forms of the essential clock protein FREQUENCY. Cell (1997) 3.32
Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors. Mol Ther (2000) 3.32
Blocker protection in the pore of a voltage-gated K+ channel and its structural implications. Nature (2000) 3.26
Proto-oncogene PML controls genes devoted to MHC class I antigen presentation. Nature (1998) 3.22
Subsequent pulmonary embolism: risk after a negative helical CT pulmonary angiogram--prospective comparison with scintigraphy. Radiology (2000) 3.06
IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J (1998) 2.99
Activation of a mitogen-activated protein kinase pathway is involved in disease resistance in tobacco. Proc Natl Acad Sci U S A (2001) 2.98
Overexpression of insulin-like growth factor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest (1997) 2.93
Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles. J Virol (1997) 2.91
Dbp5p, a cytosolic RNA helicase, is required for poly(A)+ RNA export. EMBO J (1998) 2.90
Characterization of the human cysteinyl leukotriene 2 receptor. J Biol Chem (2000) 2.89
Search for a resonance decaying into WZ boson pairs in pp collisions. Phys Rev Lett (2010) 2.83
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene (2012) 2.82
Structure of the adenylyl cyclase catalytic core. Nature (1997) 2.81
Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock. Proc Natl Acad Sci U S A (2001) 2.77
Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells. Mol Cell Biol (1986) 2.76
Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J Cell Biol (2001) 2.73
Sequential treatment of SH-SY5Y cells with retinoic acid and brain-derived neurotrophic factor gives rise to fully differentiated, neurotrophic factor-dependent, human neuron-like cells. J Neurochem (2000) 2.71
Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem (2000) 2.66
The regulation of reactive oxygen species production during programmed cell death. J Cell Biol (1998) 2.62
Regulation of the C/EBP-related gene gadd153 by glucose deprivation. Mol Cell Biol (1993) 2.59
The C8/144B monoclonal antibody recognizes cytokeratin 15 and defines the location of human hair follicle stem cells. J Cell Sci (1998) 2.58
The C termini of Arabidopsis cryptochromes mediate a constitutive light response. Cell (2000) 2.53
Nitric oxide and cutaneous active vasodilation during heat stress in humans. J Appl Physiol (1985) (1998) 2.53
Uncoupling PR gene expression from NPR1 and bacterial resistance: characterization of the dominant Arabidopsis cpr6-1 mutant. Plant Cell (1998) 2.48
On the use of thiol-modifying agents to determine channel topology. Neuropharmacology (1996) 2.47
Increased thermal stability of proteins in the presence of naturally occurring osmolytes. Biochemistry (1992) 2.47
Zinc inhibition of mitochondrial aconitase and its importance in citrate metabolism of prostate epithelial cells. J Biol Chem (1997) 2.47
Profiling serine hydrolase activities in complex proteomes. Biochemistry (2001) 2.46
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene (2012) 2.41
A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis. Neurology (2011) 2.39
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians. Diabetologia (2011) 2.37
Design of allele-specific inhibitors to probe protein kinase signaling. Curr Biol (1998) 2.36
Establishment, maintenance and description of cell lines from the tick Ixodes scapularis. J Parasitol (1994) 2.36
Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene. Neuron (1997) 2.34
The transcriptome of the arbuscular mycorrhizal fungus Glomus intraradices (DAOM 197198) reveals functional tradeoffs in an obligate symbiont. New Phytol (2011) 2.29
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway. Genes Dev (1997) 2.26
Acute motor axonal neuropathy: a frequent cause of acute flaccid paralysis in China. Ann Neurol (1993) 2.23
Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures. J Cell Biol (2001) 2.23
Odd-parity superconductivity in Sr2RuO4. Science (2004) 2.22
Systemic gene expression after intravenous DNA delivery into adult mice. Science (1993) 2.21
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia. Proc Natl Acad Sci U S A (2001) 2.21
Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J Biol Chem (2000) 2.20
Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. EMBO J (2001) 2.19
Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity (1999) 2.18
Human albumin therapy of acute ischemic stroke: marked neuroprotective efficacy at moderate doses and with a broad therapeutic window. Stroke (2001) 2.16
Loss of HuR is linked to reduced expression of proliferative genes during replicative senescence. Mol Cell Biol (2001) 2.15
Characterization of apelin, the ligand for the APJ receptor. J Neurochem (2000) 2.11
Dissecting glycoprotein quality control in the secretory pathway. Trends Biochem Sci (2001) 2.08
Method for obtaining structure and interactions from oriented lipid bilayers. Phys Rev E Stat Nonlin Soft Matter Phys (2000) 2.08
Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases. Proc Natl Acad Sci U S A (1994) 2.07
PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis. J Cell Biol (2000) 2.07
Excessive activation of the alternative complement pathway in autosomal dominant polycystic kidney disease. J Intern Med (2014) 2.06
Identification of a global repressor gene, rsmA, of Erwinia carotovora subsp. carotovora that controls extracellular enzymes, N-(3-oxohexanoyl)-L-homoserine lactone, and pathogenicity in soft-rotting Erwinia spp. J Bacteriol (1995) 2.06
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol Cell Biol (2000) 2.06
Preconditioning protects ischemic rabbit heart by protein kinase C activation. Am J Physiol (1994) 2.04
Discovery of a receptor related to the galanin receptors. FEBS Lett (1999) 2.01
Cloning and functional expression of two families of beta-subunits of the large conductance calcium-activated K+ channel. J Biol Chem (2000) 1.99
A Western-style diet induces benign and malignant neoplasms in the colon of normal C57Bl/6 mice. Carcinogenesis (2001) 1.99
Unnatural ligands for engineered proteins: new tools for chemical genetics. Annu Rev Biophys Biomol Struct (2000) 1.99
Investigating the hows and whys of DNA endoreduplication. J Exp Bot (2001) 1.97
Human hair follicle bulge cells are biochemically distinct and possess an epithelial stem cell phenotype. J Investig Dermatol Symp Proc (1999) 1.96
Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-Jun N-terminal kinase activity and AP-1-dependent gene activation. J Biol Chem (1995) 1.96
Mice lacking complex gangliosides develop Wallerian degeneration and myelination defects. Proc Natl Acad Sci U S A (1999) 1.95
Programmed myocyte cell death affects the viable myocardium after infarction in rats. Exp Cell Res (1996) 1.95
Inactivation of rsmA leads to overproduction of extracellular pectinases, cellulases, and proteases in Erwinia carotovora subsp. carotovora in the absence of the starvation/cell density-sensing signal, N-(3-oxohexanoyl)-L-homoserine lactone. Appl Environ Microbiol (1995) 1.94
Exaggerated heart rate oscillations during two meditation techniques. Int J Cardiol (1999) 1.93
Down-regulation of cyclin D1 expression by prostaglandin A(2) is mediated by enhanced cyclin D1 mRNA turnover. Mol Cell Biol (2000) 1.93
A receptor for interleukin 10 is related to interferon receptors. Proc Natl Acad Sci U S A (1993) 1.91