Published in EMBO J on January 01, 1994
Osmotic stress signaling and osmoadaptation in yeasts. Microbiol Mol Biol Rev (2002) 8.02
MAP kinase pathways in the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev (1998) 6.20
Cell wall integrity signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev (2005) 5.46
puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in Drosophila. Genes Dev (1998) 4.64
Activation and regulation of the Spc1 stress-activated protein kinase in Schizosaccharomyces pombe. Mol Cell Biol (1996) 3.18
Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. Biochim Biophys Acta (2007) 3.07
Roles of the Candida albicans mitogen-activated protein kinase homolog, Cek1p, in hyphal development and systemic candidiasis. Infect Immun (1998) 2.98
Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases. Mol Cell Biol (1997) 2.65
Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J (1996) 2.59
A walk-through of the yeast mating pheromone response pathway. Peptides (2005) 2.47
Signalling in the yeasts: an informational cascade with links to the filamentous fungi. Microbiol Mol Biol Rev (1998) 2.45
Cutting activates a 46-kilodalton protein kinase in plants. Proc Natl Acad Sci U S A (1995) 2.28
Yeast RLM1 encodes a serum response factor-like protein that may function downstream of the Mpk1 (Slt2) mitogen-activated protein kinase pathway. Mol Cell Biol (1995) 2.14
Cooperative binding interactions required for function of the Ty1 sterile responsive element. Mol Cell Biol (1997) 2.12
MAP kinase phosphatases. Genome Biol (2002) 1.88
Jasmonate-based wound signal transduction requires activation of WIPK, a tobacco mitogen-activated protein kinase. Plant Cell (1999) 1.85
A catalytic mechanism for the dual-specific phosphatases. Proc Natl Acad Sci U S A (1995) 1.68
The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism. Mol Cell Biol (1996) 1.66
Dynamic analysis of MAPK signaling using a high-throughput microfluidic single-cell imaging platform. Proc Natl Acad Sci U S A (2009) 1.52
MP2C, a plant protein phosphatase 2C, functions as a negative regulator of mitogen-activated protein kinase pathways in yeast and plants. Proc Natl Acad Sci U S A (1998) 1.51
Ptc1, a type 2C Ser/Thr phosphatase, inactivates the HOG pathway by dephosphorylating the mitogen-activated protein kinase Hog1. Mol Cell Biol (2001) 1.51
Heat stress activates the yeast high-osmolarity glycerol mitogen-activated protein kinase pathway, and protein tyrosine phosphatases are essential under heat stress. Eukaryot Cell (2002) 1.50
Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans. Mol Biol Cell (1997) 1.45
Two human cDNAs, including a homolog of Arabidopsis FUS6 (COP11), suppress G-protein- and mitogen-activated protein kinase-mediated signal transduction in yeast and mammalian cells. Mol Cell Biol (1996) 1.41
Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway. Mol Biol Cell (1995) 1.36
Mot3, a Zn finger transcription factor that modulates gene expression and attenuates mating pheromone signaling in Saccharomyces cerevisiae. Genetics (1998) 1.36
Activation of the Saccharomyces cerevisiae filamentation/invasion pathway by osmotic stress in high-osmolarity glycogen pathway mutants. Genetics (1999) 1.33
pmp1+, a suppressor of calcineurin deficiency, encodes a novel MAP kinase phosphatase in fission yeast. EMBO J (1998) 1.32
Differential regulation of the cell wall integrity mitogen-activated protein kinase pathway in budding yeast by the protein tyrosine phosphatases Ptp2 and Ptp3. Mol Cell Biol (1999) 1.32
Suppressors of a Saccharomyces cerevisiae pkc1 mutation identify alleles of the phosphatase gene PTC1 and of a novel gene encoding a putative basic leucine zipper protein. Genetics (1995) 1.28
Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomes. EMBO J (2004) 1.27
Oscillatory phosphorylation of yeast Fus3 MAP kinase controls periodic gene expression and morphogenesis. Curr Biol (2008) 1.27
MOT2 encodes a negative regulator of gene expression that affects basal expression of pheromone-responsive genes in Saccharomyces cerevisiae. Mol Cell Biol (1994) 1.23
Pheromone induction promotes Ste11 degradation through a MAPK feedback and ubiquitin-dependent mechanism. Proc Natl Acad Sci U S A (2002) 1.18
Regulation of the G-protein-coupled alpha-factor pheromone receptor by phosphorylation. Mol Cell Biol (1996) 1.18
HYS2, an essential gene required for DNA replication in Saccharomyces cerevisiae. Nucleic Acids Res (1995) 1.18
Distinct, constitutively active MAPK phosphatases function in Xenopus oocytes: implications for p42 MAPK regulation In vivo. Mol Biol Cell (1999) 1.11
Effect of the pheromone-responsive G(alpha) and phosphatase proteins of Saccharomyces cerevisiae on the subcellular localization of the Fus3 mitogen-activated protein kinase. Mol Cell Biol (2003) 1.10
Dynamic studies of scaffold-dependent mating pathway in yeast. Biophys J (2006) 1.08
A framework for mapping, visualisation and automatic model creation of signal-transduction networks. Mol Syst Biol (2012) 1.07
Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast. Mol Cell Biol (2004) 1.07
The EGP1 gene may be a positive regulator of protein phosphatase type 1 in the growth control of Saccharomyces cerevisiae. Mol Cell Biol (1995) 1.07
A specific protein-protein interaction accounts for the in vivo substrate selectivity of Ptp3 towards the Fus3 MAP kinase. Genes Dev (1999) 1.06
Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription. Nat Cell Biol (2011) 1.04
Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein-coupled receptor Ste2. Mol Cell Biol (2014) 1.02
Characterization of a murine gene encoding a developmentally regulated cytoplasmic dual-specificity mitogen-activated protein kinase phosphatase. Biochem J (2002) 0.96
Use of pleiotropy to model genetic interactions in a population. PLoS Genet (2012) 0.95
Identification and characterization of FAR3, a gene required for pheromone-mediated G1 arrest in Saccharomyces cerevisiae. Genetics (1996) 0.95
Pheromone-induced degradation of Ste12 contributes to signal attenuation and the specificity of developmental fate. Eukaryot Cell (2006) 0.95
Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol Biol Cell (1999) 0.93
POG1, a novel yeast gene, promotes recovery from pheromone arrest via the G1 cyclin CLN2. Genetics (1999) 0.91
The mating-specific G(alpha) protein of Saccharomyces cerevisiae downregulates the mating signal by a mechanism that is dependent on pheromone and independent of G(beta)(gamma) sequestration. Mol Cell Biol (1996) 0.87
Combined computational and experimental analysis reveals mitogen-activated protein kinase-mediated feedback phosphorylation as a mechanism for signaling specificity. Mol Biol Cell (2012) 0.85
The pheromone-induced nuclear accumulation of the Fus3 MAPK in yeast depends on its phosphorylation state and on Dig1 and Dig2. BMC Cell Biol (2007) 0.85
Dynamic localization of Fus3 mitogen-activated protein kinase is necessary to evoke appropriate responses and avoid cytotoxic effects. Mol Cell Biol (2010) 0.84
The Dynamical Systems Properties of the HOG Signaling Cascade. J Signal Transduct (2011) 0.83
Quantitative measurement of protein relocalization in live cells. Biophys J (2013) 0.83
G protein betagamma complex-mediated apoptosis by familial Alzheimer's disease mutant of APP. EMBO J (1997) 0.82
Different modulation of the outputs of yeast MAPK-mediated pathways by distinct stimuli and isoforms of the dual-specificity phosphatase Msg5. Mol Genet Genomics (2009) 0.82
Control of adaptation to mating pheromone by G protein beta subunits of Saccharomyces cerevisiae. Genetics (1994) 0.82
Inhibition of mitogen-activated protein kinase by a Drosophila dual-specific phosphatase. Biochem J (2000) 0.81
Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiae. J Biol Chem (2011) 0.81
Afr1p regulates the Saccharomyces cerevisiae alpha-factor receptor by a mechanism that is distinct from receptor phosphorylation and endocytosis. Genetics (1998) 0.81
Substitutions in the pheromone-responsive Gbeta protein of Saccharomyces cerevisiae confer a defect in recovery from pheromone treatment. Genetics (1998) 0.80
Point mutations identify a conserved region of the saccharomyces cerevisiae AFR1 gene that is essential for both the pheromone signaling and morphogenesis functions. Genetics (2000) 0.80
Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms. Mol Genet Genomics (2011) 0.79
Multiple Phosphatases Regulate Carbon Source-Dependent Germination and Primary Metabolism in Aspergillus nidulans. G3 (Bethesda) (2015) 0.79
Spatial and temporal signal processing and decision making by MAPK pathways. J Cell Biol (2017) 0.76
PTEN redundancy: overexpressing lpten, a homolog of Dictyostelium discoideum ptenA, the ortholog of human PTEN, rescues all behavioral defects of the mutant ptenA-. PLoS One (2014) 0.76
A conserved non-canonical docking mechanism regulates the binding of dual specificity phosphatases to cell integrity mitogen-activated protein kinases (MAPKs) in budding and fission yeasts. PLoS One (2014) 0.75
Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK. Mol Biol Cell (2015) 0.75
An Analog-sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway. J Biol Chem (2016) 0.75
Role and regulation of MKP-1 in airway inflammation. Respir Res (2017) 0.75
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal Biochem (1991) 16.18
Detection and quantification of phosphotyrosine in proteins. Methods Enzymol (1983) 11.89
PROSITE: a dictionary of sites and patterns in proteins. Nucleic Acids Res (1991) 9.18
Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein. Mol Cell Biol (1987) 7.38
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product. Science (1992) 5.55
G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase. Cell (1990) 5.55
The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein. Cell (1989) 5.07
FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation. Cell (1990) 4.89
The yeast SCG1 gene: a G alpha-like protein implicated in the a- and alpha-factor response pathway. Cell (1987) 4.85
Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes. Science (1991) 4.72
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction. Cell (1987) 4.50
Nucleotide sequences of STE2 and STE3, cell type-specific sterile genes from Saccharomyces cerevisiae. EMBO J (1985) 4.37
Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2. Cell (1990) 4.27
Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae. Mol Cell Biol (1987) 4.17
Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor. Proc Natl Acad Sci U S A (1986) 4.07
A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae. Cell (1989) 3.99
The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components. EMBO J (1992) 3.91
Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein. Genes Dev (1992) 3.65
FAR1 links the signal transduction pathway to the cell cycle machinery in yeast. Cell (1993) 3.59
The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene. Nucleic Acids Res (1985) 3.59
p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast. EMBO J (1991) 3.55
Physiological characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromones. Mol Cell Biol (1982) 3.37
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature (1992) 3.37
A Tyr/Ser protein phosphatase encoded by vaccinia virus. Nature (1991) 3.35
STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes. Genes Dev (1989) 3.28
Signal transduction during pheromone response in yeast. Annu Rev Cell Biol (1991) 3.08
The yeast STE12 protein binds to the DNA sequence mediating pheromone induction. Proc Natl Acad Sci U S A (1989) 3.01
Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR. EMBO J (1990) 2.94
Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1. Genes Dev (1992) 2.92
Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase. Genes Dev (1992) 2.85
PAC-1: a mitogen-induced nuclear protein tyrosine phosphatase. Science (1993) 2.80
FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction. Proc Natl Acad Sci U S A (1991) 2.79
MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro. Nature (1993) 2.33
Overproduction of the yeast STE12 protein leads to constitutive transcriptional induction. Genes Dev (1990) 2.30
The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. Oncogene (1993) 2.23
Constitutive mutants in the yeast pheromone response: ordered function of the gene products. Cell (1989) 2.22
cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein. Oncogene (1992) 2.17
Pheromone-induced signal transduction in Saccharomyces cerevisiae requires the sequential function of three protein kinases. Mol Cell Biol (1993) 2.03
Mutations in a gene encoding the alpha subunit of a Saccharomyces cerevisiae G protein indicate a role in mating pheromone signaling. Mol Cell Biol (1988) 1.98
Regulation of the yeast pheromone response pathway by G protein subunits. EMBO J (1990) 1.97
SGV1 encodes a CDC28/cdc2-related kinase required for a G alpha subunit-mediated adaptive response to pheromone in S. cerevisiae. Cell (1991) 1.74
Expression cloning of a human dual-specificity phosphatase. Proc Natl Acad Sci U S A (1992) 1.59
Yeast cells recover from mating pheromone alpha factor-induced division arrest by desensitization in the absence of alpha factor destruction. J Biol Chem (1984) 1.56
FAR1 is required for posttranscriptional regulation of CLN2 gene expression in response to mating pheromone. Mol Cell Biol (1993) 1.50
GPA1Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.31
A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation. Proc Natl Acad Sci U S A (1992) 1.27
G protein mutations that alter the pheromone response in Saccharomyces cerevisiae. Mol Cell Biol (1990) 1.09
Primary structure of a gene for subunit V of the cytochrome c oxidase from Saccharomyces cerevisiae. Curr Genet (1985) 0.99
In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell (1985) 11.63
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science (1997) 9.53
The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway. Nature (1999) 7.31
Nucleotide sequence of bacteriophage fd DNA. Nucleic Acids Res (1978) 7.25
Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J Biol Chem (2001) 7.21
Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains. Proc Natl Acad Sci U S A (1968) 6.82
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science (1995) 6.81
Nuclear localization of the C2H2 zinc finger protein Msn2p is regulated by stress and protein kinase A activity. Genes Dev (1998) 6.75
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science (1998) 6.62
G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase. Cell (1990) 5.55
The Cognitive Abilities Screening Instrument (CASI): a practical test for cross-cultural epidemiological studies of dementia. Int Psychogeriatr (1994) 5.47
Studies on bacteriophage fd DNA. IV. The sequence of messenger RNA for the major coat protein gene. J Mol Biol (1977) 5.34
Mating signals control expression of mutations resulting from insertion of a transposable repetitive element adjacent to diverse yeast genes. Cell (1980) 5.20
Isolation and characterization of yeast mutants deficient in adenylate cyclase and cAMP-dependent protein kinase. Proc Natl Acad Sci U S A (1982) 5.04
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell (1991) 4.98
Expression of genes in yeast using the ADCI promoter. Methods Enzymol (1983) 4.94
A cyclin B homolog in S. cerevisiae: chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis. Cell (1991) 4.90
Nucleotide sequence of Escherichia coli K-12 replication origin. Proc Natl Acad Sci U S A (1979) 4.85
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction. Cell (1987) 4.50
Function of positive regulatory gene gal4 in the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae: evidence that the GAL81 region codes for part of the gal4 protein. J Bacteriol (1980) 4.36
Nucleotide sequence of small ColE1 derivatives: structure of the regions essential for autonomous replication and colicin E1 immunity. Mol Gen Genet (1979) 4.30
PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors. Mol Cell Biol (1986) 4.23
Genetic control of galactokinase synthesis in Saccharomyces cerevisiae: evidence for constitutive expression of the positive regulatory gene gal4. J Bacteriol (1978) 4.18
Interaction of super-repressible and dominant constitutive mutations for the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae. Mol Gen Genet (1977) 4.14
The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF. Nature (1999) 4.01
Retrotransposons of rice involved in mutations induced by tissue culture. Proc Natl Acad Sci U S A (1996) 4.00
Replication origin of the Escherichia coli K-12 chromosome: the size and structure of the minimum DNA segment carrying the information for autonomous replication. Mol Gen Genet (1980) 3.99
TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway. Mol Cell (2000) 3.90
Cyclin-B homologs in Saccharomyces cerevisiae function in S phase and in G2. Genes Dev (1992) 3.83
Synthesis and assembly of hepatitis B virus surface antigen particles in yeast. Nature (1982) 3.82
Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein. Genes Dev (1992) 3.65
FAR1 links the signal transduction pathway to the cell cycle machinery in yeast. Cell (1993) 3.59
MKK1 and MKK2, which encode Saccharomyces cerevisiae mitogen-activated protein kinase-kinase homologs, function in the pathway mediated by protein kinase C. Mol Cell Biol (1993) 3.54
TAB1: an activator of the TAK1 MAPKKK in TGF-beta signal transduction. Science (1996) 3.48
A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Mol Cell Biol (1993) 3.47
A protective role of gamma/delta T cells in primary infection with Listeria monocytogenes in mice. J Exp Med (1992) 3.37
Primary structure of the alpha-subunit of transducin and its relationship to ras proteins. Nature (1985) 3.28
STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes. Genes Dev (1989) 3.28
IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae. Mol Cell Biol (1989) 3.17
Integrin dynamics and matrix assembly: tensin-dependent translocation of alpha(5)beta(1) integrins promotes early fibronectin fibrillogenesis. J Cell Biol (2000) 3.13
Recruitment of Mec1 and Ddc1 checkpoint proteins to double-strand breaks through distinct mechanisms. Science (2001) 3.13
S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein. Cell (1990) 3.09
MOR1 is essential for organizing cortical microtubules in plants. Nature (2001) 3.07
Osmotic stress-induced gene expression in Saccharomyces cerevisiae requires Msn1p and the novel nuclear factor Hot1p. Mol Cell Biol (1999) 3.04
Nucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases. Proc Natl Acad Sci U S A (1986) 2.95
Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1. Genes Dev (1992) 2.92
Initiation of meiosis in yeast mutants defective in adenylate cyclase and cyclic AMP-dependent protein kinase. Cell (1983) 2.91
Mcm1 is required to coordinate G2-specific transcription in Saccharomyces cerevisiae. Mol Cell Biol (1995) 2.85
Sequence of promoter for coat protein gene of bacteriophage fd. Nature (1976) 2.82
Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters. Nature (2000) 2.74
Recessive mutations conferring resistance to carbon catabolite repression of galactokinase synthesis in Saccharomyces cerevisiae. J Bacteriol (1983) 2.73
STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast. Genes Dev (1990) 2.72
A gene encoding a mitogen-activated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, cold, and water stress in Arabidopsis thaliana. Proc Natl Acad Sci U S A (1996) 2.72
A new role for MCM1 in yeast: cell cycle regulation of SW15 transcription. Genes Dev (1991) 2.70
Primary gastric B-cell lymphoma: results of a prospective multicenter study. The German-Austrian Gastrointestinal Lymphoma Study Group. Gastroenterology (2000) 2.65
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J Biol Chem (1996) 2.64
The proliferation of MAP kinase signaling pathways in yeast. Curr Opin Cell Biol (1995) 2.60
XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J (1999) 2.54
Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions. Proc Natl Acad Sci U S A (1988) 2.54
TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop. J Biol Chem (2000) 2.53
Hepatocyte growth factor gene therapy of liver cirrhosis in rats. Nat Med (1999) 2.51
Control of cell division in Saccharomyces cerevisiae mutants defective in adenylate cyclase and cAMP-dependent protein kinase. Exp Cell Res (1983) 2.48
Kinase activity-dependent nuclear export opposes stress-induced nuclear accumulation and retention of Hog1 mitogen-activated protein kinase in the budding yeast Saccharomyces cerevisiae. Mol Biol Cell (1999) 2.46
Expression of a human gene for interferon in yeast. Nature (1981) 2.46
Predictive value of microalbuminuria in medical ICU patients: results of a pilot study. Chest (2001) 2.43
The CaMKII UNC-43 activates the MAPKKK NSY-1 to execute a lateral signaling decision required for asymmetric olfactory neuron fates. Cell (2001) 2.43
Nucleotide sequence of the asnA gene coding for asparagine synthetase of E. coli K-12. Nucleic Acids Res (1981) 2.42
Distortion of proximodistal information causes JNK-dependent apoptosis in Drosophila wing. Nature (1999) 2.42
Combination therapy with fluconazole and flucytosine for cryptococcal meningitis in Ugandan patients with AIDS. Clin Infect Dis (1998) 2.40
Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression. J Biol Chem (1999) 2.40
IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein. Mol Cell Biol (1990) 2.40
Segregation of TRAF6-mediated signaling pathways clarifies its role in osteoclastogenesis. EMBO J (2001) 2.37
Structure of the Saccharomyces cerevisiae HO gene and analysis of its upstream regulatory region. Mol Cell Biol (1986) 2.36
CDC33 encodes mRNA cap-binding protein eIF-4E of Saccharomyces cerevisiae. Mol Cell Biol (1988) 2.33
MAP kinase-related FUS3 from S. cerevisiae is activated by STE7 in vitro. Nature (1993) 2.33
MAP kinase and Wnt pathways converge to downregulate an HMG-domain repressor in Caenorhabditis elegans. Nature (1999) 2.32
Prevalent connexin 26 gene (GJB2) mutations in Japanese. J Med Genet (2000) 2.29
Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation. Proc Natl Acad Sci U S A (1991) 2.26
IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-myc. Cell (1992) 2.25
Stress-induced map kinase Hog1 is part of transcription activation complexes. Mol Cell (2001) 2.23
The structure and evolution of ribosomal and 5S DNAs in Xenopus laevis and Xenopus mulleri. Cold Spring Harb Symp Quant Biol (1974) 2.22
Structure and gene organization in the transformed Hind III-G fragment of Ad12. Cell (1980) 2.22
The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis. Curr Biol (2001) 2.22
Stimulatory effects of yeast and mammalian 14-3-3 proteins on the Raf protein kinase. Science (1994) 2.21
Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. J Cell Biol (1999) 2.21
Activation regions in a yeast transposon have homology to mating type control sequences and to mammalian enhancers. Proc Natl Acad Sci U S A (1985) 2.20
The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3. Nature (1998) 2.18
Survivin promotes cell proliferation in human hepatocellular carcinoma. Hepatology (2000) 2.15
Role of TAK1 and TAB1 in BMP signaling in early Xenopus development. EMBO J (1998) 2.15
Yeast RLM1 encodes a serum response factor-like protein that may function downstream of the Mpk1 (Slt2) mitogen-activated protein kinase pathway. Mol Cell Biol (1995) 2.14
Cooperative binding interactions required for function of the Ty1 sterile responsive element. Mol Cell Biol (1997) 2.12
Identification of the structural gene and nonsense alleles for adenylate cyclase in Saccharomyces cerevisiae. J Bacteriol (1984) 2.09
Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae. Mol Cell Biol (2001) 2.09
Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway. Mol Cell Biol (1997) 2.07