Published in J Virol on October 01, 1996
Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. J Virol (1998) 4.71
Human gene targeting by viral vectors. Nat Genet (1998) 3.02
Genetic fate of recombinant adeno-associated virus vector genomes in muscle. J Virol (2003) 2.07
Adeno-associated virus vector integration junctions. J Virol (1997) 2.03
Design and packaging of adeno-associated virus gene targeting vectors. J Virol (2000) 1.54
Novel adeno-associated virus vector vaccine restricts replication of simian immunodeficiency virus in macaques. J Virol (2005) 1.36
Reduction in levels of the cyclin-dependent kinase inhibitor p27(kip-1) coupled with transforming growth factor beta neutralization induces cell-cycle entry and increases retroviral transduction of primitive human hematopoietic cells. Proc Natl Acad Sci U S A (1998) 1.26
High-fidelity correction of mutations at multiple chromosomal positions by adeno-associated virus vectors. J Virol (1999) 1.24
Transduction of human embryonic stem cells by ecotropic retroviral vectors. Nucleic Acids Res (2006) 1.19
Recombinant adeno-associated virus mediates a high level of gene transfer but less efficient integration in the K562 human hematopoietic cell line. J Virol (1997) 1.12
Adaptation of chimeric retroviruses in vitro and in vivo: isolation of avian retroviral vectors with extended host range. J Virol (2001) 1.09
Adeno-associated virus vectors and hematology. Blood (1999) 1.03
Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins. Mol Ther (2010) 0.94
Adeno-associated virus type 2-mediated transfer of ecotropic retrovirus receptor cDNA allows ecotropic retroviral transduction of established and primary human cells. J Virol (1997) 0.91
Development of high-titer retroviral producer cell lines by using Cre-mediated recombination. J Virol (1997) 0.77
Selective extraction of polyoma DNA from infected mouse cell cultures. J Mol Biol (1967) 106.91
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci U S A (1992) 35.45
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapy. Proc Natl Acad Sci U S A (1994) 8.13
A safe packaging line for gene transfer: separating viral genes on two different plasmids. J Virol (1988) 7.87
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection. Cell (1989) 7.64
Site-specific integration by adeno-associated virus. Proc Natl Acad Sci U S A (1990) 7.06
Helper-free stocks of recombinant adeno-associated viruses: normal integration does not require viral gene expression. J Virol (1989) 6.69
Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors. J Virol (1996) 6.22
Use of adeno-associated virus as a general transduction vector for mammalian cells. Curr Top Microbiol Immunol (1992) 6.16
Targeted integration of adeno-associated virus (AAV) into human chromosome 19. EMBO J (1991) 6.13
Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis. J Virol (1996) 5.94
The basic science of gene therapy. Science (1993) 5.94
Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection. Mol Cell Biol (1990) 5.81
Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. Proc Natl Acad Sci U S A (1982) 5.73
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain. Nat Genet (1994) 5.49
Adeno-associated virus general transduction vectors: analysis of proviral structures. J Virol (1988) 4.64
A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J Virol (1987) 4.57
Use of adeno-associated virus as a mammalian DNA cloning vector: transduction of neomycin resistance into mammalian tissue culture cells. Proc Natl Acad Sci U S A (1984) 3.92
T lymphocyte-directed gene therapy for ADA- SCID: initial trial results after 4 years. Science (1995) 3.87
Expression and structure of the human NGF receptor. Cell (1986) 3.82
Transfer of genes to humans: early lessons and obstacles to success. Science (1995) 3.64
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector. Proc Natl Acad Sci U S A (1993) 3.59
Adeno-associated virus (AAV) Rep proteins mediate complex formation between AAV DNA and its integration site in human DNA. Proc Natl Acad Sci U S A (1994) 3.59
Use of retroviral vectors for gene transfer and expression. Methods Enzymol (1993) 3.50
Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter. Genomics (1991) 3.47
A neutralizable epitope common to the envelope glycoproteins of ecotropic, polytropic, xenotropic, and amphotropic murine leukemia viruses. J Virol (1990) 3.00
Gene therapy in peripheral blood lymphocytes and bone marrow for ADA- immunodeficient patients. Science (1995) 2.79
Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses. J Virol (1993) 2.77
Adeno-associated viruses: an update. Adv Virus Res (1987) 2.71
Adeno-associated virus vectors preferentially transduce cells in S phase. Proc Natl Acad Sci U S A (1994) 2.62
Prospects for the use of adeno-associated virus as a vector for human gene therapy. Hum Gene Ther (1994) 2.52
DNA-damaging agents greatly increase the transduction of nondividing cells by adeno-associated virus vectors. J Virol (1994) 2.50
Adeno-associated virus vectors for gene therapy. Gene Ther (1995) 2.32
Detection of receptor-specific murine leukemia virus binding to cells by immunofluorescence analysis. J Virol (1992) 2.25
Asymmetric replication in vitro from a human sequence element is dependent on adeno-associated virus Rep protein. J Virol (1995) 2.23
Adeno-associated virus vector for high-frequency integration, expression, and rescue of genes in mammalian cells. Mol Cell Biol (1985) 2.21
DNA synthesis and topoisomerase inhibitors increase transduction by adeno-associated virus vectors. Proc Natl Acad Sci U S A (1995) 2.20
Engraftment of gene-modified umbilical cord blood cells in neonates with adenosine deaminase deficiency. Nat Med (1995) 2.15
Recombinant junctions formed by site-specific integration of adeno-associated virus into an episome. J Virol (1995) 2.02
Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proc Natl Acad Sci U S A (1992) 1.82
Adeno-associated virus vector gene expression occurs in nondividing cells in the absence of vector DNA integration. Am J Respir Cell Mol Biol (1994) 1.80
Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. Blood (1994) 1.75
Adeno-associated virus: a vector system for efficient introduction and integration of DNA into a variety of mammalian cell types. Mol Cell Biol (1988) 1.72
Efficient gene transfer into nondividing cells by adeno-associated virus-based vectors. J Virol (1994) 1.63
Cell lines for the production of recombinant adeno-associated virus. Hum Gene Ther (1995) 1.62
Adeno-associated virus vectors transduce primary cells much less efficiently than immortalized cells. J Virol (1995) 1.58
Gene-marking to trace origin of relapse after autologous bone-marrow transplantation. Lancet (1993) 1.53
High-efficiency transfer of the T cell co-stimulatory molecule B7-2 to lymphoid cells using high-titer recombinant adeno-associated virus vectors. Hum Gene Ther (1995) 1.52
Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells. Blood (1994) 1.45
Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector. J Clin Invest (1994) 1.39
Inducible, high-level production of infectious murine leukemia retroviral vector particles pseudotyped with vesicular stomatitis virus G envelope protein. Hum Gene Ther (1995) 1.37
Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells. Proc Natl Acad Sci U S A (1994) 1.28
Adeno-associated virus 2-mediated high efficiency gene transfer into immature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood. J Exp Med (1994) 1.26
A new strategy for large-scale preparation of high-titer recombinant adeno-associated virus vectors by using packaging cell lines and sulfonated cellulose column chromatography. Hum Gene Ther (1996) 1.17
Adenovirus-mediated transfer of the amphotropic retrovirus receptor cDNA increases retroviral transduction in cultured cells. Hum Gene Ther (1995) 1.07
Retroviral infection and expression of cationic amino acid transporters in rodent hepatocytes. J Virol (1993) 0.94
Gene transfer into hematopoietic progenitor and stem cells: progress and problems. Stem Cells (1994) 0.89
A gene transfer strategy for making bone marrow cells resistant to trimetrexate. Blood (1996) 0.84
Gene marking after bone marrow transplantation. Eur J Cancer (1994) 0.78
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev (1993) 17.09
Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science (2000) 10.81
Sequence of the gene for the constant region of the mu chain of Balb/c mouse immunoglobulin. Gene (1981) 8.45
Genome of the bacterium Streptococcus pneumoniae strain R6. J Bacteriol (2001) 7.97
A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nat Genet (1996) 6.58
Jak2 is essential for signaling through a variety of cytokine receptors. Cell (1998) 5.92
Osteopetrosis in mice lacking NF-kappaB1 and NF-kappaB2. Nat Med (1997) 5.72
An analysis of statistical term strength and its use in the indexing and retrieval of molecular biology texts. Comput Biol Med (1996) 5.36
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN. Nat Med (2000) 5.04
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C. Nat Med (2000) 4.98
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development (2001) 4.89
Recombinant adeno-associated virus for muscle directed gene therapy. Nat Med (1997) 4.87
Efficacy of deferoxamine in preventing complications of iron overload in patients with thalassemia major. N Engl J Med (1994) 4.86
Processed pseudogenes: characteristics and evolution. Annu Rev Genet (1985) 4.40
A viral inhibitor of peptide transporters for antigen presentation. Nature (1995) 4.26
Submucosal glands are the predominant site of CFTR expression in the human bronchus. Nat Genet (1992) 4.12
Latent Semantic Indexing of medical diagnoses using UMLS semantic structures. Proc Annu Symp Comput Appl Med Care (1991) 4.09
An oligomer complementary to c-myc mRNA inhibits proliferation of HL-60 promyelocytic cells and induces differentiation. Mol Cell Biol (1988) 4.08
Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells. Genes Dev (1990) 4.07
A family of long reiterated DNA sequences, one copy of which is next to the human beta globin gene. Nucleic Acids Res (1980) 3.91
CTX-M-5, a novel cefotaxime-hydrolyzing beta-lactamase from an outbreak of Salmonella typhimurium in Latvia. Antimicrob Agents Chemother (1998) 3.74
Kinetic interactions of tazobactam with beta-lactamases from all major structural classes. Antimicrob Agents Chemother (1993) 3.74
Inducible production of c-fos antisense RNA inhibits 3T3 cell proliferation. Proc Natl Acad Sci U S A (1986) 3.71
Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F. Mol Cell Biol (1992) 3.58
Unexpected relationships between four large deletions in the human beta-globin gene cluster. Cell (1983) 3.57
Characterization of IMI-1 beta-lactamase, a class A carbapenem-hydrolyzing enzyme from Enterobacter cloacae. Antimicrob Agents Chemother (1996) 3.44
Simple correction method for k-space trajectory deviations in MRI. J Magn Reson (1998) 3.35
5-azacytidine selectively increases gamma-globin synthesis in a patient with beta+ thalassemia. N Engl J Med (1982) 3.29
The functional human dihydrofolate reductase gene. J Biol Chem (1984) 3.28
Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc Natl Acad Sci U S A (1996) 3.16
Transduction of dendritic cells by DNA viral vectors directs the immune response to transgene products in muscle fibers. J Virol (1998) 3.14
Role of the aromatic hydrocarbon receptor and [Ah] gene battery in the oxidative stress response, cell cycle control, and apoptosis. Biochem Pharmacol (2000) 3.01
RNA processing errors in patients with beta-thalassemia. Proc Natl Acad Sci U S A (1982) 2.99
Chromosomal organization of the human dihydrofolate reductase genes: dispersion, selective amplification, and a novel form of polymorphism. Proc Natl Acad Sci U S A (1984) 2.99
Vitamin D3 up-regulated protein 1 mediates oxidative stress via suppressing the thioredoxin function. J Immunol (2000) 2.96
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP. Immunity (1997) 2.93
A mouse alpha-globin-related pseudogene lacking intervening sequences. Nature (1980) 2.92
Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene. Cancer Res (2000) 2.91
The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways. J Biol Chem (1998) 2.88
Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma. Proc Natl Acad Sci U S A (1999) 2.87
Differences in human alpha-, beta- and delta-globin gene expression in monkey kidney cells. Cell (1982) 2.78
Interlocked feedback loops contribute to the robustness of the Neurospora circadian clock. Proc Natl Acad Sci U S A (2001) 2.77
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. Science (1999) 2.70
Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation. EMBO J (1998) 2.68
Direct gene transfer of human CFTR into human bronchial epithelia of xenografts with E1-deleted adenoviruses. Nat Genet (1993) 2.67
Mini-prep in ten minutes. Biotechniques (1990) 2.67
Adhesion formation after previous caesarean section-a meta-analysis and systematic review. BJOG (2010) 2.66
Molecular mechanism and species specificity of TAP inhibition by herpes simplex virus ICP47. EMBO J (1996) 2.64
Diverse roles of matrix metalloproteinases and tissue inhibitors of metalloproteinases in neuroinflammation and cerebral ischemia. Neuroscience (2008) 2.55
Augmentation by erythropoietin of the fetal-hemoglobin response to hydroxyurea in sickle cell disease. N Engl J Med (1993) 2.50
Investigation of low frequency drift in fMRI signal. Neuroimage (1999) 2.49
Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: biological efficacy study. Hum Gene Ther (1993) 2.48
Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice. J Clin Invest (1990) 2.37
A replication-defective human adenovirus recombinant serves as a highly efficacious vaccine carrier. Virology (1996) 2.35
Continuous subcutaenous administration of deferoxamine in patients with iron overload. N Engl J Med (1977) 2.31
Expression of the human c-fms proto-oncogene in hematopoietic cells and its deletion in the 5q- syndrome. Cell (1985) 2.28
The effect on blood-pressure of organ extracts. J Physiol (1911) 2.24
The human MDM-2 oncogene is overexpressed in leukemias. Blood (1993) 2.24
Generation of enhancer trap lines in Arabidopsis and characterization of expression patterns in the inflorescence. Plant J (1999) 2.24
H(2)(15)O PET validation of steady-state arterial spin tagging cerebral blood flow measurements in humans. Magn Reson Med (2000) 2.20
Coiled-coil domain-mediated FRQ-FRQ interaction is essential for its circadian clock function in Neurospora. EMBO J (2001) 2.19
Beta O-39 thalassemia gene: a premature termination codon causes beta-mRNA deficiency without affecting cytoplasmic beta-mRNA stability. Blood (1984) 2.17
Developmental regulation of human globin genes. Annu Rev Biochem (1985) 2.16
Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis. Blood (1999) 2.14
An evaluation of computer assisted clinical classification algorithms. Proc Annu Symp Comput Appl Med Care (1994) 2.14
Biology of adenovirus vectors with E1 and E4 deletions for liver-directed gene therapy. J Virol (1996) 2.12
Gene-for-genes interactions between cotton R genes and Xanthomonas campestris pv. malvacearum avr genes. Mol Plant Microbe Interact (1993) 2.10
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Nat Commun (2013) 2.10
Cloning and expression of a cloxacillin-hydrolyzing enzyme and a cephalosporinase from Aeromonas sobria AER 14M in Escherichia coli: requirement for an E. coli chromosomal mutation for efficient expression of the class D enzyme. Antimicrob Agents Chemother (1994) 2.10
Atomistic free-volume zones and inelastic deformation of metallic glasses. Nat Mater (2010) 2.08
Adenovirus-mediated transfer of the CFTR gene to lung of nonhuman primates: toxicity study. Hum Gene Ther (1993) 2.07
Hukou and non-hukou migrations in China: comparisons and contrasts. Int J Popul Geogr (2000) 2.06
Fluorescent treponemal antibodies in fractionated syphilitic sera. The immunoglobulin class. Arch Dermatol (1969) 2.06
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. Mol Cell Biol (1993) 2.05
Salmonella enterica serovar typhi uses type IVB pili to enter human intestinal epithelial cells. Infect Immun (2000) 2.04
Cloning and characterization of DNA sequences surrounding the human gamma-, delta-, and beta-globin genes. Proc Natl Acad Sci U S A (1980) 2.04
Inducibility of the HS II enhancer depends on binding of an erythroid specific nuclear protein. Nucleic Acids Res (1990) 2.01
Phylogenetic position of the genus Hydrogenobacter. Int J Syst Bacteriol (1994) 1.98
Beta Thalassemia: mutations which affect processing of the beta-Globin mRNA precursor. Cell (1980) 1.98
Mapping transient, randomly occurring neuropsychological events using independent component analysis. Neuroimage (2001) 1.93
Impaired macrophage function and enhanced T cell-dependent immune response in mice lacking CCR5, the mouse homologue of the major HIV-1 coreceptor. J Immunol (1998) 1.92
microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity. Br J Cancer (2010) 1.90
pepM is an essential gene in Salmonella typhimurium. J Bacteriol (1989) 1.85
Pure red-cell aplasia of 10 years' duration due to persistent parvovirus B19 infection and its cure with immunoglobulin therapy. N Engl J Med (1989) 1.85
Combination of interleukins 3 and 6 preserves stem cell function in culture and enhances retrovirus-mediated gene transfer into hematopoietic stem cells. Proc Natl Acad Sci U S A (1989) 1.84
Purification, identification, and characterization of an osmotic response element binding protein. Biochem Biophys Res Commun (2000) 1.84
Regulated high level expression of a human gamma-globin gene introduced into erythroid cells by an adeno-associated virus vector. Proc Natl Acad Sci U S A (1992) 1.82
Empty and peptide-containing conformers of class I major histocompatibility complex molecules expressed in Drosophila melanogaster cells. Proc Natl Acad Sci U S A (1992) 1.79
Expression of the human c-fms proto-oncogene product (colony-stimulating factor-1 receptor) on peripheral blood mononuclear cells and choriocarcinoma cell lines. J Clin Invest (1986) 1.77
Nopp140 functions as a molecular link between the nucleolus and the coiled bodies. J Cell Biol (1998) 1.77
Sexual behaviour and contraceptive use among unmarried, young women migrant workers in five cities in China. Reprod Health Matters (2001) 1.77
Hepatic iron stores and plasma ferritin concentration in patients with sickle cell anemia and thalassemia major. Am J Hematol (1993) 1.76
Recombinant adeno-associated virus-mediated gene transfer into hematopoietic progenitor cells. Blood (1994) 1.75
Translation of rabbit haemoglobin messenger RNA by thalassaemic and non-thalassaemic ribosomes. Nat New Biol (1971) 1.75
Factors influencing in vivo transduction by recombinant adeno-associated viral vectors expressing the human factor IX cDNA. Blood (2001) 1.74
Isolation and translation of hemoglobin messenger RNA from thalassemia, sickle cell anemia, and normal human reticulocytes. J Clin Invest (1971) 1.74
Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator. J Exp Med (1994) 1.73