Published in Cell on October 18, 1996
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Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinase. Mol Cell Biol (2002) 1.19
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A basic motif in the N-terminal region of RAG1 enhances V(D)J recombination activity. Mol Cell Biol (1997) 1.15
Footprint analysis of the RAG protein recombination signal sequence complex for V(D)J type recombination. Mol Cell Biol (1998) 1.15
Nicking is asynchronous and stimulated by synapsis in 12/23 rule-regulated V(D)J cleavage. Nucleic Acids Res (1997) 1.11
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The origins of the Rag genes--from transposition to V(D)J recombination. Semin Immunol (2009) 1.07
A C-terminal region of RAG1 contacts the coding DNA during V(D)J recombination. Mol Cell Biol (2001) 1.06
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DNA mismatches and GC-rich motifs target transposition by the RAG1/RAG2 transposase. Nucleic Acids Res (2003) 1.05
Omenn syndrome: a disorder of Rag1 and Rag2 genes. J Clin Immunol (1999) 1.03
RAG transposase can capture and commit to target DNA before or after donor cleavage. Mol Cell Biol (2001) 1.00
V(D)J recombination: in vitro coding joint formation. Mol Cell Biol (1997) 1.00
RAG-1 and RAG-2-dependent assembly of functional complexes with V(D)J recombination substrates in solution. Mol Cell Biol (1997) 0.98
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Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase. Nucleic Acids Res (2003) 0.98
A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2. J Mol Biol (2009) 0.98
The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences. Mol Cell Biol (1997) 0.97
Activation of 12/23-RSS-dependent RAG cleavage by hSWI/SNF complex in the absence of transcription. Mol Cell (2008) 0.95
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Conditional RAG-1 mutants block the hairpin formation step of V(D)J recombination. Mol Cell Biol (2001) 0.93
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Functional organization of single and paired V(D)J cleavage complexes. Mol Cell Biol (2001) 0.92
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Role of recombination activating genes in the generation of antigen receptor diversity and beyond. Immunology (2012) 0.87
Synapsis of recombination signal sequences located in cis and DNA underwinding in V(D)J recombination. Mol Cell Biol (2004) 0.86
Non-consensus heptamer sequences destabilize the RAG post-cleavage complex, making ends available to alternative DNA repair pathways. Nucleic Acids Res (2010) 0.86
Quantitative analyses of RAG-RSS interactions and conformations revealed by atomic force microscopy. Biochemistry (2008) 0.85
Identification and characterization of a gain-of-function RAG-1 mutant. Mol Cell Biol (2006) 0.85
A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity. J Mol Biol (2009) 0.84
In vitro processing of the 3'-overhanging DNA in the postcleavage complex involved in V(D)J joining. Mol Cell Biol (2004) 0.84
DNA cleavage activity of the V(D)J recombination protein RAG1 is autoregulated. Mol Cell Biol (2004) 0.84
Rag-1 mutations associated with B-cell-negative scid dissociate the nicking and transesterification steps of V(D)J recombination. Mol Cell Biol (2001) 0.84
RAG and HMGB1 create a large bend in the 23RSS in the V(D)J recombination synaptic complexes. Nucleic Acids Res (2013) 0.84
Elucidating the domain architecture and functions of non-core RAG1: the capacity of a non-core zinc-binding domain to function in nuclear import and nucleic acid binding. BMC Biochem (2011) 0.84
Footprint analysis of recombination signal sequences in the 12/23 synaptic complex of V(D)J recombination. Mol Cell Biol (2002) 0.84
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Thermal dependency of RAG1 self-association properties. BMC Biochem (2008) 0.80
The DNA-binding region of RAG 1 is not a homeodomain. Genome Biol (2002) 0.80
V(D)J recombination frequency is affected by the sequence interposed between a pair of recombination signals: sequence comparison reveals a putative recombinational enhancer element. Nucleic Acids Res (1997) 0.79
Molecular analysis of T-B-NK+ severe combined immunodeficiency and Omenn syndrome cases in Saudi Arabia. BMC Med Genet (2009) 0.78
An interdomain boundary in RAG1 facilitates cooperative binding to RAG2 in formation of the V(D)J recombinase complex. Protein Sci (2015) 0.78
Cooperative recruitment of HMGB1 during V(D)J recombination through interactions with RAG1 and DNA. Nucleic Acids Res (2013) 0.78
Recruitment of RAG1 and RAG2 to Chromatinized DNA during V(D)J Recombination. Mol Cell Biol (2015) 0.76
Biochemical Characterization of Nonamer Binding Domain of RAG1 Reveals its Thymine Preference with Respect to Length and Position. Sci Rep (2016) 0.75
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