Published in Mol Biol Cell on June 01, 1998
Force measurements in E-cadherin-mediated cell doublets reveal rapid adhesion strengthened by actin cytoskeleton remodeling through Rac and Cdc42. J Cell Biol (2004) 3.06
Rho GTPases have diverse effects on the organization of the actin filament system. Biochem J (2004) 2.23
Rho protein crosstalk: another social network? Trends Cell Biol (2011) 2.19
Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not beta1 integrins. Mol Cell Biol (2000) 1.83
Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism. Mol Biol Cell (2002) 1.74
Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor. Mol Biol Cell (2003) 1.72
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Scaffold mediated regulation of MAPK signaling and cytoskeletal dynamics: a perspective. Cell Signal (2007) 1.65
M-cadherin activates Rac1 GTPase through the Rho-GEF trio during myoblast fusion. Mol Biol Cell (2007) 1.51
Statin-induced inhibition of the Rho-signaling pathway activates PPARalpha and induces HDL apoA-I. J Clin Invest (2001) 1.47
SGEF, a RhoG guanine nucleotide exchange factor that stimulates macropinocytosis. Mol Biol Cell (2004) 1.42
RhoA GTPase regulates M-cadherin activity and myoblast fusion. Mol Biol Cell (2005) 1.40
Critical activities of Rac1 and Cdc42Hs in skeletal myogenesis: antagonistic effects of JNK and p38 pathways. Mol Biol Cell (2000) 1.39
Vav2 is required for cell spreading. J Cell Biol (2001) 1.36
Small GTPase RhoG is a key regulator for neurite outgrowth in PC12 cells. Mol Cell Biol (2000) 1.34
Cdc42 and actin control polarized expression of TI-VAMP vesicles to neuronal growth cones and their fusion with the plasma membrane. Mol Biol Cell (2005) 1.26
Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration. J Cell Sci (2008) 1.22
Regulation of Cdc42-mediated morphological effects: a novel function for p53. EMBO J (2002) 1.21
The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory function. Mol Cell Biol (2002) 1.20
Immunological function in mice lacking the Rac-related GTPase RhoG. Mol Cell Biol (2004) 1.19
Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells. Mol Biol Cell (2007) 1.12
miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling. EMBO J (2012) 1.07
Retinoic acid leads to cytoskeletal rearrangement through AMPK-Rac1 and stimulates glucose uptake through AMPK-p38 MAPK in skeletal muscle cells. J Biol Chem (2008) 1.06
N-cadherin association with lipid rafts regulates its dynamic assembly at cell-cell junctions in C2C12 myoblasts. Mol Biol Cell (2005) 1.06
Involvement of the Rho/Rac family member RhoG in caveolar endocytosis. Oncogene (2006) 1.03
Coordinate regulation of Salmonella enterica serovar Typhimurium invasion of epithelial cells by the Arp2/3 complex and Rho GTPases. Infect Immun (2003) 1.03
Kinectin is a key effector of RhoG microtubule-dependent cellular activity. Mol Cell Biol (2001) 1.01
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The GTP/GDP cycling of rho GTPase TCL is an essential regulator of the early endocytic pathway. Mol Biol Cell (2003) 0.98
The small GTPase RhoG mediates glioblastoma cell invasion. Mol Cancer (2012) 0.98
RhoG promotes neural progenitor cell proliferation in mouse cerebral cortex. Mol Biol Cell (2009) 0.95
RhoG protein regulates platelet granule secretion and thrombus formation in mice. J Biol Chem (2013) 0.90
Activation of AMP-activated protein kinase is essential for lysophosphatidic acid-induced cell migration in ovarian cancer cells. J Biol Chem (2011) 0.90
Yersinia pseudotuberculosis virulence determinants invasin, YopE, and YopT modulate RhoG activity and localization. Infect Immun (2009) 0.87
Apoptotic cell recognition receptors and scavenger receptors. Immunol Rev (2016) 0.87
RhoG protein regulates glycoprotein VI-Fc receptor γ-chain complex-mediated platelet activation and thrombus formation. J Biol Chem (2013) 0.86
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p104 binds to Rac1 and reduces its activity during myotube differentiation of C2C12 cell. ScientificWorldJournal (2014) 0.75
Human serum albumin and oxidative stress in preeclamptic women and the mechanism of albumin for stress reduction. Heliyon (2017) 0.75
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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell (1995) 24.99
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Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs. Cell (1995) 9.30
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The small GTPases Rho and Rac are required for the establishment of cadherin-dependent cell-cell contacts. J Cell Biol (1997) 5.15
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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J Biol Chem (1995) 4.62
A role for Rac in Tiam1-induced membrane ruffling and invasion. Nature (1995) 4.59
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes. J Biol Chem (1995) 4.03
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RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science (1996) 3.30
The guanine nucleotide exchange factor Tiam1 affects neuronal morphology; opposing roles for the small GTPases Rac and Rho. J Cell Biol (1997) 3.28
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Two GTPases, Cdc42 and Rac, bind directly to a protein implicated in the immunodeficiency disorder Wiskott-Aldrich syndrome. Curr Biol (1996) 3.13
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A novel partner for the GTP-bound forms of rho and rac. FEBS Lett (1995) 2.52
Regulation of phosphorylation pathways by p21 GTPases. The p21 Ras-related Rho subfamily and its role in phosphorylation signalling pathways. Eur J Biochem (1996) 2.47
Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation. Mol Cell Biol (1997) 2.44
Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity. Proc Natl Acad Sci U S A (1997) 2.14
A novel oncogene, ost, encodes a guanine nucleotide exchange factor that potentially links Rho and Rac signaling pathways. EMBO J (1994) 2.09
Cytokinesis arrest and redistribution of actin-cytoskeleton regulatory components in cells expressing the Rho GTPase CDC42Hs. J Cell Sci (1996) 2.08
Identification of a novel Rac1-interacting protein involved in membrane ruffling. EMBO J (1996) 2.00
Lysophosphatidic acid and microtubule-destabilizing agents stimulate fibronectin matrix assembly through Rho-dependent actin stress fiber formation and cell contraction. Mol Biol Cell (1997) 1.96
Endosome dynamics regulated by a Rho protein. Nature (1996) 1.90
The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization. Mol Cell Biol (1997) 1.78
RhoA-dependent phosphorylation and relocalization of ERM proteins into apical membrane/actin protrusions in fibroblasts. Mol Biol Cell (1998) 1.62
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Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase. J Biol Chem (1996) 1.55
Fas- or ceramide-induced apoptosis is mediated by a Rac1-regulated activation of Jun N-terminal kinase/p38 kinases and GADD153. J Biol Chem (1997) 1.51
Geranylgeranylated rho small GTPase(s) are essential for the degradation of p27Kip1 and facilitate the progression from G1 to S phase in growth-stimulated rat FRTL-5 cells. J Biol Chem (1997) 1.38
RalGDS-like factor (Rlf) is a novel Ras and Rap 1A-associating protein. Oncogene (1996) 1.35
The small GTPases Cdc42Hs, Rac1 and RhoG delineate Raf-independent pathways that cooperate to transform NIH3T3 cells. Curr Biol (1997) 1.28
Phosphatidylinositol 4,5-bisphosphate provides an alternative to guanine nucleotide exchange factors by stimulating the dissociation of GDP from Cdc42Hs. J Biol Chem (1996) 1.28
Rho is a negative regulator of human monocyte spreading. J Immunol (1996) 1.27
Inactivation of the small GTP binding protein Rho induces multinucleate cell formation and apoptosis in murine T lymphoma EL4. J Immunol (1996) 1.17
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