Published in J Mol Biol on July 03, 1998
Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process. EMBO J (2002) 3.57
Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM. Nat Struct Mol Biol (2005) 1.92
Ultrastructural and functional analyses of recombinant influenza virus ribonucleoproteins suggest dimerization of nucleoprotein during virus amplification. J Virol (2000) 1.86
Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 A resolution. EMBO J (2000) 1.69
Detection and selective dissociation of intact ribosomes in a mass spectrometer. Proc Natl Acad Sci U S A (2000) 1.65
Single-particle reconstruction of biological macromolecules in electron microscopy--30 years. Q Rev Biophys (2009) 1.61
Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. J Cell Biol (2000) 1.60
Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structures. Biophys J (2000) 1.52
Location of translational initiation factor IF3 on the small ribosomal subunit. Proc Natl Acad Sci U S A (1999) 1.51
Localization of an NH(2)-terminal disease-causing mutation hot spot to the "clamp" region in the three-dimensional structure of the cardiac ryanodine receptor. J Biol Chem (2007) 1.43
RNA location and modeling of a WD40 repeat domain within the vault. RNA (2000) 1.37
Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes. Proc Natl Acad Sci U S A (2004) 1.31
Characterization of the nuclear export adaptor protein Nmd3 in association with the 60S ribosomal subunit. J Cell Biol (2010) 1.30
Definition and estimation of resolution in single-particle reconstructions. Structure (2010) 1.27
Three-dimensional reconstruction of the recombinant type 3 ryanodine receptor and localization of its amino terminus. Proc Natl Acad Sci U S A (2001) 1.26
Three-dimensional localization of serine 2808, a phosphorylation site in cardiac ryanodine receptor. J Biol Chem (2007) 1.24
Structural aspects of RbfA action during small ribosomal subunit assembly. Mol Cell (2007) 1.20
Three-dimensional location of the imperatoxin A binding site on the ryanodine receptor. J Cell Biol (1999) 1.17
Monolithic microfluidic mixing-spraying devices for time-resolved cryo-electron microscopy. J Struct Biol (2009) 1.11
Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins. Proc Natl Acad Sci U S A (2007) 1.07
Localization of the dantrolene-binding sequence near the FK506-binding protein-binding site in the three-dimensional structure of the ryanodine receptor. J Biol Chem (2011) 1.05
CLIC2-RyR1 interaction and structural characterization by cryo-electron microscopy. J Mol Biol (2009) 1.04
Molecular Machines: putting the pieces together. J Cell Biol (2001) 1.03
Three-dimensional visualization of FKBP12.6 binding to an open conformation of cardiac ryanodine receptor. Biophys J (2005) 1.03
Localization of PKA phosphorylation site, Ser(2030), in the three-dimensional structure of cardiac ryanodine receptor. Biochem J (2008) 1.02
Calculation of the relative geometry of tRNAs in the ribosome from directed hydroxyl-radical probing data. RNA (2000) 0.99
Structural basis of the iron storage function of frataxin from single-particle reconstruction of the iron-loaded oligomer. Biochemistry (2008) 0.98
Cryoelectron microscopy reveals new features in the three-dimensional structure of phosphorylase kinase. Protein Sci (2005) 0.97
Calmodulin-binding locations on the skeletal and cardiac ryanodine receptors. J Biol Chem (2012) 0.95
The ribosome structure controls and directs mRNA entry, translocation and exit dynamics. Phys Biol (2008) 0.93
Selecting rRNA binding sites for the ribosomal proteins L4 and L6 from randomly fragmented rRNA: application of a method called SERF. Proc Natl Acad Sci U S A (2000) 0.92
Comparison of fungal 80 S ribosomes by cryo-EM reveals diversity in structure and conformation of rRNA expansion segments. J Mol Biol (2007) 0.88
Interactions of an essential Bacillus subtilis GTPase, YsxC, with ribosomes. J Bacteriol (2007) 0.88
Structural and functional characterization of ryanodine receptor-natrin toxin interaction. Biophys J (2008) 0.87
Site-directed hydroxyl radical probing of 30S ribosomal subunits by using Fe(II) tethered to an interruption in the 16S rRNA chain. Proc Natl Acad Sci U S A (1999) 0.81
Deformed grids for single-particle cryo-electron microscopy of specimens exhibiting a preferred orientation. J Struct Biol (2013) 0.81
Reciprocal space representations of helical objects and their projection images for helices constructed from motifs without spherical symmetry. Ultramicroscopy (2008) 0.79
Proteins neighboring 18S rRNA conserved sequences 609-618 and 1047-1061 within the 40S human ribosomal subunit. RNA (1999) 0.79
Organization of the 16S rRNA around its 5' terminus determined by photochemical crosslinking in the 30S ribosomal subunit. RNA (2000) 0.77
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
The UK Standardisation of Breast Radiotherapy (START) Trial B of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet (2008) 6.50
A ratchet-like inter-subunit reorganization of the ribosome during translocation. Nature (2000) 6.29
Three-dimensional reconstruction from a single-exposure, random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli. J Microsc (1987) 5.18
Structure of the 80S ribosome from Saccharomyces cerevisiae--tRNA-ribosome and subunit-subunit interactions. Cell (2001) 5.01
Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit. Science (2001) 4.79
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer. Oncogene (2012) 4.30
Use of multivariate statistics in analysing the images of biological macromolecules. Ultramicroscopy (1981) 4.19
Three-dimensional reconstruction of single particles embedded in ice. Ultramicroscopy (1992) 3.99
Solution structure of the E. coli 70S ribosome at 11.5 A resolution. Cell (2000) 3.99
Alignment of conduits for the nascent polypeptide chain in the ribosome-Sec61 complex. Science (1997) 3.95
The ribosome at improved resolution: new techniques for merging and orientation refinement in 3D cryo-electron microscopy of biological particles. Ultramicroscopy (1994) 3.68
A model of protein synthesis based on cryo-electron microscopy of the E. coli ribosome. Nature (1995) 3.56
The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial. Lancet Oncol (2008) 3.31
Echo-planar time course MRI of cat brain oxygenation changes. Magn Reson Med (1991) 3.12
Reduction of background problems in nonradioactive northern and Southern blot analyses enables higher sensitivity than 32P-based hybridizations. Anal Biochem (1993) 2.93
Architecture of the protein-conducting channel associated with the translating 80S ribosome. Cell (2001) 2.84
Computer averaging of electron micrographs of 40S ribosomal subunits. Science (1981) 2.79
Cryo-electron microscopy and three-dimensional reconstruction of the calcium release channel/ryanodine receptor from skeletal muscle. J Cell Biol (1994) 2.58
EF-G-dependent GTP hydrolysis induces translocation accompanied by large conformational changes in the 70S ribosome. Nat Struct Biol (1999) 2.56
Trail making test, part B as a measure of executive control: validation using a set-switching paradigm. J Clin Exp Neuropsychol (2000) 2.55
Visualization of elongation factor G on the Escherichia coli 70S ribosome: the mechanism of translocation. Proc Natl Acad Sci U S A (1998) 2.53
Parameters for the preparation of Escherichia coli ribosomes and ribosomal subunits active in tRNA binding. Methods Enzymol (1988) 2.51
Total reconstitution of functionally active 50S ribosomal subunits from Escherichia coli. Proc Natl Acad Sci U S A (1974) 2.51
Three-dimensional architecture of the calcium channel/foot structure of sarcoplasmic reticulum. Nature (1989) 2.37
Evidence that the G2661 region of 23S rRNA is located at the ribosomal binding sites of both elongation factors. Biochimie (1987) 2.36
An immortalized rat liver stellate cell line (HSC-T6): a new cell model for the study of retinoid metabolism in vitro. J Lipid Res (2000) 2.36
Glucose dehydrogenase from Acinetobacter calcoaceticus: a 'quinoprotein'. FEBS Lett (1979) 2.34
A common-lines based method for determining orientations for N > 3 particle projections simultaneously. Ultramicroscopy (1996) 2.32
Properties of the NAD(P)H-dependent xylose reductase from the xylose-fermenting yeast Pichia stipitis. Biochem J (1985) 2.31
Alopecia universalis associated with a mutation in the human hairless gene. Science (1998) 2.23
Effects of dopamine on postural control in parkinsonian subjects: scaling, set, and tone. J Neurophysiol (1996) 2.23
Three tRNA binding sites on Escherichia coli ribosomes. Proc Natl Acad Sci U S A (1981) 2.15
Incorporation of six additional proteins to complete the assembly map of the 50 S subunit from Escherichia coli ribosomes. J Biol Chem (1987) 2.15
A 9 A resolution X-ray crystallographic map of the large ribosomal subunit. Cell (1998) 2.14
Double-tilt electron tomography. Ultramicroscopy (1995) 2.12
Pubomyoaponeurotic foramen and posterior groin plait for groin hernia. Hernia (2003) 2.05
Assembly map of the large subunit (50S) of Escherichia coli ribosomes. Proc Natl Acad Sci U S A (1982) 1.94
The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Mol Cell (2001) 1.94
Identification of the chloramphenicol-binding protein in Escherichia coli ribosomes by partial reconstitution. Proc Natl Acad Sci U S A (1973) 1.94
Characterization of Prostaglandin G/H Synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts. Gastroenterology (1996) 1.92
Bovine serum amine oxidase: a mammalian enzyme having covalently bound PQQ as prosthetic group. FEBS Lett (1984) 1.92
Visualization of protein S1 within the 30S ribosomal subunit and its interaction with messenger RNA. Proc Natl Acad Sci U S A (2001) 1.91
Minimal set of ribosomal components for reconstitution of the peptidyltransferase activity. EMBO J (1982) 1.87
Reconstruction of glutamine synthetase using computer averaging. Ultramicroscopy (1978) 1.85
Purification and properties of methanol dehydrogenase from Hyphomicrobium x. Biochim Biophys Acta (1978) 1.83
Role of 5S RNA in assembly and function of the 50S subunit from Escherichia coli. Proc Natl Acad Sci U S A (1976) 1.82
Climate change and the integrity of science. Science (2010) 1.80
A ribosome-associated peptidyl-prolyl cis/trans isomerase identified as the trigger factor. EMBO J (1995) 1.79
High pressure effects on protein structure and function. Proteins (1996) 1.78
Direct visualization of A-, P-, and E-site transfer RNAs in the Escherichia coli ribosome. Science (1996) 1.78
Ribosomal proteins. Protein compositions of biosynthetic precursors and artifical subparticles from ribosomal subunits in Escherichia coli K 12. Eur J Biochem (1971) 1.77
Ultrastructure of the calcium release channel of sarcoplasmic reticulum. J Cell Biol (1988) 1.76
Structure of the colcemid-treated PtK1 kinetochore outer plate as determined by high voltage electron microscopic tomography. J Cell Biol (1993) 1.74
Three-dimensional reconstruction with contrast transfer function correction from energy-filtered cryoelectron micrographs: procedure and application to the 70S Escherichia coli ribosome. J Struct Biol (1997) 1.72
Endothelial progenitor cells correlate with lesion volume and growth in acute stroke. Neurology (2010) 1.69
Three-dimensional cryo-electron microscopy localization of EF2 in the Saccharomyces cerevisiae 80S ribosome at 17.5 A resolution. EMBO J (2000) 1.69
The elongation factor 3 unique in higher fungi and essential for protein biosynthesis is an E site factor. J Biol Chem (1995) 1.69
Preparation of functional ribosomal complexes and effect of buffer conditions on tRNA positions observed by cryoelectron microscopy. Methods Enzymol (2000) 1.68
Ribosomal components from Escherichia coli 50 S subunits involved in the reconstitution of peptidyltransferase activity. J Biol Chem (1981) 1.68
Identifying male college students' perceived health needs, barriers to seeking help, and recommendations to help men adopt healthier lifestyles. J Am Coll Health (2000) 1.67
Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding protein. Am J Clin Nutr (1999) 1.65
Detection and selective dissociation of intact ribosomes in a mass spectrometer. Proc Natl Acad Sci U S A (2000) 1.65
Psychiatric disorders in elderly from the Indian sub-continent living in Bradford. Int J Geriatr Psychiatry (1997) 1.62
Effect of buffer conditions on the position of tRNA on the 70 S ribosome as visualized by cryoelectron microscopy. J Biol Chem (1999) 1.62
Visualization of tRNA movements on the Escherichia coli 70S ribosome during the elongation cycle. J Cell Biol (2000) 1.60
A prospective, randomized study of continuous versus intermittent nebulized albuterol for severe status asthmaticus in children. Crit Care Med (1993) 1.60
Correspondence analysis of aligned images of biological particles. J Mol Biol (1982) 1.60
A new 3-D reconstruction scheme applied to the 50S ribosomal subunit of E. coli. J Microsc (1986) 1.60
Genetic association of the human corticotropin releasing hormone receptor 1 (CRHR1) with binge drinking and alcohol intake patterns in two independent samples. Mol Psychiatry (2006) 1.59