Published in Mol Cell Biol on August 01, 1999
Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science (2003) 12.90
Processing bodies require RNA for assembly and contain nontranslating mRNAs. RNA (2005) 6.54
General translational repression by activators of mRNA decapping. Cell (2005) 6.40
Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay. Mol Cell Biol (2002) 5.80
A Sm-like protein complex that participates in mRNA degradation. EMBO J (2000) 5.08
The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA (2001) 4.80
Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression. Genome Biol (2003) 4.45
Global signatures of protein and mRNA expression levels. Mol Biosyst (2009) 4.43
Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA. PLoS Biol (2009) 4.32
Genome-wide protein interaction screens reveal functional networks involving Sm-like proteins. Yeast (2000) 3.85
A parsimonious model for gene regulation by miRNAs. Science (2011) 3.79
The control of mRNA decapping and P-body formation. Mol Cell (2008) 3.58
Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430. Curr Biol (2006) 3.51
The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast. EMBO J (2000) 3.38
mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E. Mol Cell Biol (2000) 3.06
Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs. Curr Opin Cell Biol (2009) 3.01
The two proteins Pat1p (Mrt1p) and Spb8p interact in vivo, are required for mRNA decay, and are functionally linked to Pab1p. Mol Cell Biol (2000) 3.00
Multiple portions of poly(A)-binding protein stimulate translation in vivo. EMBO J (2000) 2.78
The DEAD box protein Dhh1 stimulates the decapping enzyme Dcp1. EMBO J (2002) 2.65
A novel mRNA-decapping activity in HeLa cytoplasmic extracts is regulated by AU-rich elements. EMBO J (2001) 2.63
A role for the eIF4E-binding protein 4E-T in P-body formation and mRNA decay. J Cell Biol (2005) 2.51
Analysis of recombinant yeast decapping enzyme. RNA (2003) 2.50
Analysis of P-body assembly in Saccharomyces cerevisiae. Mol Biol Cell (2007) 2.37
A network of multiple regulatory layers shapes gene expression in fission yeast. Mol Cell (2007) 2.29
P-bodies and stress granules: possible roles in the control of translation and mRNA degradation. Cold Spring Harb Perspect Biol (2012) 2.19
Multiple mRNA decapping enzymes in mammalian cells. Mol Cell (2010) 2.12
Optimisation of transgene action at the post-transcriptional level: high quality parthenocarpic fruits in industrial tomatoes. BMC Biotechnol (2002) 2.07
Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes. Mol Cell Biol (2000) 2.07
RNA degradation in Saccharomyces cerevisae. Genetics (2012) 2.06
Widespread use of poly(A) tail length control to accentuate expression of the yeast transcriptome. RNA (2007) 1.99
Cap-dependent deadenylation of mRNA. EMBO J (2000) 1.96
Tristetraprolin (TTP): interactions with mRNA and proteins, and current thoughts on mechanisms of action. Biochim Biophys Acta (2013) 1.90
Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation: implications for the control of mRNA decapping. Mol Biol Cell (1999) 1.88
Functional characterization of the mammalian mRNA decapping enzyme hDcp2. RNA (2003) 1.88
Accumulation of polyadenylated mRNA, Pab1p, eIF4E, and eIF4G with P-bodies in Saccharomyces cerevisiae. Mol Biol Cell (2007) 1.83
Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae. Genetics (2001) 1.80
Computational modeling of eukaryotic mRNA turnover. RNA (2001) 1.79
Pat1 contains distinct functional domains that promote P-body assembly and activation of decapping. Mol Cell Biol (2007) 1.64
The RNA polymerase II subunit Rpb4p mediates decay of a specific class of mRNAs. Genes Dev (2005) 1.60
Poly(A)-binding proteins regulate both mRNA deadenylation and decapping in yeast cytoplasmic extracts. RNA (2001) 1.59
Stress-specific composition, assembly and kinetics of stress granules in Saccharomyces cerevisiae. J Cell Sci (2010) 1.58
The decapping activator Lsm1p-7p-Pat1p complex has the intrinsic ability to distinguish between oligoadenylated and polyadenylated RNAs. RNA (2007) 1.54
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues. Mol Cell (2014) 1.52
Novel G-protein complex whose requirement is linked to the translational status of the cell. Mol Cell Biol (2002) 1.48
The yeast EDC1 mRNA undergoes deadenylation-independent decapping stimulated by Not2p, Not4p, and Not5p. EMBO J (2005) 1.47
Folding free energies of 5'-UTRs impact post-transcriptional regulation on a genomic scale in yeast. PLoS Comput Biol (2005) 1.46
Regulation of c-myc mRNA decay by translational pausing in a coding region instability determinant. Mol Cell Biol (2002) 1.43
Translation-independent inhibition of mRNA deadenylation during stress in Saccharomyces cerevisiae. RNA (2006) 1.40
Coupled evolution of transcription and mRNA degradation. PLoS Biol (2011) 1.40
The enhancer of decapping proteins, Edc1p and Edc2p, bind RNA and stimulate the activity of the decapping enzyme. RNA (2003) 1.39
The DEAD-box RNA helicase Ded1p affects and accumulates in Saccharomyces cerevisiae P-bodies. Mol Biol Cell (2007) 1.35
Poly(A)-binding-protein-mediated regulation of hDcp2 decapping in vitro. EMBO J (2004) 1.33
Reconsidering movement of eukaryotic mRNAs between polysomes and P bodies. Mol Cell (2011) 1.31
The DEAD-box protein Dhh1 promotes decapping by slowing ribosome movement. PLoS Biol (2012) 1.30
The target of rapamycin signaling pathway regulates mRNA turnover in the yeast Saccharomyces cerevisiae. Mol Biol Cell (2001) 1.27
The Arabidopsis cucumovirus multiplication 1 and 2 loci encode translation initiation factors 4E and 4G. J Virol (2004) 1.26
Arabidopsis decapping 5 is required for mRNA decapping, P-body formation, and translational repression during postembryonic development. Plant Cell (2009) 1.24
Mutations in the Saccharomyces cerevisiae LSM1 gene that affect mRNA decapping and 3' end protection. Genetics (2005) 1.23
Structural and functional control of the eukaryotic mRNA decapping machinery. Biochim Biophys Acta (2012) 1.23
Functional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codons. Mol Cell Biol (2011) 1.22
Deciphering the rules by which 5'-UTR sequences affect protein expression in yeast. Proc Natl Acad Sci U S A (2013) 1.18
RISC-target interaction: cleavage and translational suppression. Biochim Biophys Acta (2008) 1.18
Scd6 targets eIF4G to repress translation: RGG motif proteins as a class of eIF4G-binding proteins. Mol Cell (2012) 1.18
Identification of an mRNA-decapping regulator implicated in X-linked mental retardation. Mol Cell (2006) 1.17
Transcript-specific decapping and regulated stability by the human Dcp2 decapping protein. Mol Cell Biol (2007) 1.17
Sbp1p affects translational repression and decapping in Saccharomyces cerevisiae. Mol Cell Biol (2006) 1.09
Stm1 modulates translation after 80S formation in Saccharomyces cerevisiae. RNA (2011) 1.08
The intimate relationships of mRNA decay and translation. Trends Genet (2013) 1.07
PAB1 self-association precludes its binding to poly(A), thereby accelerating CCR4 deadenylation in vivo. Mol Cell Biol (2007) 1.03
Interrelations between translation and general mRNA degradation in yeast. Wiley Interdiscip Rev RNA (2014) 1.03
Gene codon composition determines differentiation-dependent expression of a viral capsid gene in keratinocytes in vitro and in vivo. Mol Cell Biol (2005) 1.03
Chemical-genetic profile analysis of five inhibitory compounds in yeast. BMC Chem Biol (2010) 1.02
A fission yeast homolog of Int-6, the mammalian oncoprotein and eIF3 subunit, induces drug resistance when overexpressed. Mol Biol Cell (2000) 1.02
The DHH1/RCKp54 family of helicases: an ancient family of proteins that promote translational silencing. Biochim Biophys Acta (2013) 1.01
Evidence that poly(A) binding protein has an evolutionarily conserved function in facilitating mRNA biogenesis and export. RNA (2003) 1.01
Stm1 modulates mRNA decay and Dhh1 function in Saccharomyces cerevisiae. Genetics (2008) 1.00
3' poly(A) is dispensable for translation. Proc Natl Acad Sci U S A (2000) 1.00
CAF1 plays an important role in mRNA deadenylation separate from its contact to CCR4. Nucleic Acids Res (2007) 0.99
Multiple Nudix family proteins possess mRNA decapping activity. RNA (2013) 0.97
PUF3 acceleration of deadenylation in vivo can operate independently of CCR4 activity, possibly involving effects on the PAB1-mRNP structure. J Mol Biol (2010) 0.97
lsm1 mutations impairing the ability of the Lsm1p-7p-Pat1p complex to preferentially bind to oligoadenylated RNA affect mRNA decay in vivo. RNA (2008) 0.96
Regulation of protein synthesis by eIF4E phosphorylation in adult cardiocytes: the consequence of secondary structure in the 5'-untranslated region of mRNA. Biochem J (2004) 0.96
Activation of decapping involves binding of the mRNA and facilitation of the post-binding steps by the Lsm1-7-Pat1 complex. RNA (2009) 0.94
MicroRNA-target interactions: new insights from genome-wide approaches. Ann N Y Acad Sci (2012) 0.93
A eukaryotic translation initiation factor 4E-binding protein promotes mRNA decapping and is required for PUF repression. Mol Cell Biol (2012) 0.92
The RNA-binding protein Y14 inhibits mRNA decapping and modulates processing body formation. Mol Biol Cell (2012) 0.92
Host factors that control long terminal repeat retrotransposons in Saccharomyces cerevisiae: implications for regulation of mammalian retroviruses. Eukaryot Cell (2007) 0.92
Yeast mRNA cap-binding protein Cbc1/Sto1 is necessary for the rapid reprogramming of translation after hyperosmotic shock. Mol Biol Cell (2011) 0.91
Serum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stability. Nucleic Acids Res (2005) 0.90
Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis. BMC Genomics (2008) 0.90
Diauxic shift-dependent relocalization of decapping activators Dhh1 and Pat1 to polysomal complexes. Nucleic Acids Res (2011) 0.89
A mutation in a skin-specific isoform of SMARCAD1 causes autosomal-dominant adermatoglyphia. Am J Hum Genet (2011) 0.89
Mutational analysis of a Dcp2-binding element reveals general enhancement of decapping by 5'-end stem-loop structures. Nucleic Acids Res (2009) 0.88
Mass spectrometric identification of proteins that interact through specific domains of the poly(A) binding protein. Mol Genet Genomics (2012) 0.87
The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs. Elife (2016) 0.87
Not4-dependent translational repression is important for cellular protein homeostasis in yeast. EMBO J (2015) 0.85
Ribosome profiling reveals an important role for translational control in circadian gene expression. Genome Res (2015) 0.85
Activation of AP-1-dependent transcription by a truncated translation initiation factor. Eukaryot Cell (2005) 0.85
Nutrients and the Pkh1/2 and Pkc1 protein kinases control mRNA decay and P-body assembly in yeast. J Biol Chem (2010) 0.85
General and MicroRNA-Mediated mRNA Degradation Occurs on Ribosome Complexes in Drosophila Cells. Mol Cell Biol (2015) 0.84
A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation. Genes Dev (1993) 9.28
mRNA stability in mammalian cells. Microbiol Rev (1995) 8.78
The 3' to 5' degradation of yeast mRNAs is a general mechanism for mRNA turnover that requires the SKI2 DEVH box protein and 3' to 5' exonucleases of the exosome complex. EMBO J (1998) 7.83
Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript. Genes Dev (1994) 7.57
Two distinct destabilizing elements in the c-fos message trigger deadenylation as a first step in rapid mRNA decay. Genes Dev (1991) 7.51
Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G. EMBO J (1996) 7.28
Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells. Annu Rev Biochem (1996) 7.08
The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell (1989) 7.00
The translation initiation factor eIF-4E binds to a common motif shared by the translation factor eIF-4 gamma and the translational repressors 4E-binding proteins. Mol Cell Biol (1995) 6.99
Degradation of mRNA in eukaryotes. Cell (1995) 6.81
Yeast cells lacking 5'-->3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure. Mol Cell Biol (1993) 6.36
Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3' AU-rich sequences. Nature (1988) 6.35
An essential component of the decapping enzyme required for normal rates of mRNA turnover. Nature (1996) 6.15
5'-terminal cap structure in eucaryotic messenger ribonucleic acids. Microbiol Rev (1980) 6.14
Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (eIF4G) with picornaviral proteases. Implications for cap-dependent and cap-independent translational initiation. J Biol Chem (1995) 5.96
Turnover mechanisms of the stable yeast PGK1 mRNA. Mol Cell Biol (1995) 5.83
Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae. Mol Cell Biol (1990) 5.47
A mouse cytoplasmic exoribonuclease (mXRN1p) with preference for G4 tetraplex substrates. J Cell Biol (1997) 4.93
A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5'-terminal cap in mRNA. Proc Natl Acad Sci U S A (1978) 4.45
Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae. Microbiol Rev (1996) 4.34
New initiation factor activity required for globin mRNA translation. J Biol Chem (1983) 4.31
Mutations affecting stability and deadenylation of the yeast MFA2 transcript. Genes Dev (1992) 4.20
Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast. Genes Dev (1995) 4.15
Gene products that promote mRNA turnover in Saccharomyces cerevisiae. Mol Cell Biol (1992) 4.00
A small segment of the MAT alpha 1 transcript promotes mRNA decay in Saccharomyces cerevisiae: a stimulatory role for rare codons. Mol Cell Biol (1993) 3.91
TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function. Mol Cell Biol (1993) 3.85
Involvement of eukaryotic initiation factor 4A in the cap recognition process. J Biol Chem (1983) 3.70
The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro. Mol Cell Biol (1989) 3.69
Translational blockade imposed by cytokine-derived UA-rich sequences. Science (1989) 3.68
Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiae. Mol Cell Biol (1996) 3.58
Messenger RNA deadenylylation precedes decapping in mammalian cells. Proc Natl Acad Sci U S A (1997) 3.51
Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA. J Biol Chem (1994) 3.37
Cap recognition and the entry of mRNA into the protein synthesis initiation cycle. Trends Biochem Sci (1988) 3.17
Translation initiation factors eIF-iso4G and eIF-4B interact with the poly(A)-binding protein and increase its RNA binding activity. J Biol Chem (1997) 2.87
Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3' UTR and does not involve poly(A) tail shortening. EMBO J (1994) 2.70
The rate-limiting step in yeast PGK1 mRNA degradation is an endonucleolytic cleavage in the 3'-terminal part of the coding region. Mol Cell Biol (1992) 2.27
Translation initiation factor 4A from Saccharomyces cerevisiae: analysis of residues conserved in the D-E-A-D family of RNA helicases. Mol Cell Biol (1991) 2.27
mRNA cap-binding protein: cloning of the gene encoding protein synthesis initiation factor eIF-4E from Saccharomyces cerevisiae. Mol Cell Biol (1987) 2.21
Poly(A) tail shortening is the translation-dependent step in c-myc mRNA degradation. Mol Cell Biol (1990) 2.06
Purified yeast translational initiation factor eIF-3 is an RNA-binding protein complex that contains the PRT1 protein. J Biol Chem (1994) 2.06
A single amino acid substitution in yeast eIF-5A results in mRNA stabilization. EMBO J (1998) 2.00
Analysis of mutations in the yeast mRNA decapping enzyme. Genetics (1999) 1.93
A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with eIF4G for binding to eIF4E. EMBO J (1997) 1.92
GCD10, a translational repressor of GCN4, is the RNA-binding subunit of eukaryotic translation initiation factor-3. Genes Dev (1995) 1.86
Identification and characterization of cap-binding proteins from yeast. J Biol Chem (1989) 1.85
Translation in Saccharomyces cerevisiae: initiation factor 4E-dependent cell-free system. Mol Cell Biol (1989) 1.68
Overexpression of poly(A) binding protein prevents maturation-specific deadenylation and translational inactivation in Xenopus oocytes. EMBO J (1996) 1.62
Interactions of the eIF-4F subunits in the yeast Saccharomyces cerevisiae. J Biol Chem (1992) 1.56
Glucose-dependent turnover of the mRNAs encoding succinate dehydrogenase peptides in Saccharomyces cerevisiae: sequence elements in the 5' untranslated region of the Ip mRNA play a dominant role. Mol Biol Cell (1995) 1.51
Mutational analysis of the Prt1 protein subunit of yeast translation initiation factor 3. Mol Cell Biol (1995) 1.35
Regulated poly(A) tail shortening in somatic cells mediated by cap-proximal translational repressor proteins and ribosome association. RNA (1997) 1.26
Disruption of ribosomal scanning on the 5'-untranslated region, and not restriction of translational initiation per se, modulates the stability of nonaberrant mRNAs in the yeast Saccharomyces cerevisiae. J Biol Chem (1997) 1.10
Protein synthesis in eukaryotic organisms: new insights into the function of translation initiation factor eIF-3. Bioessays (1995) 1.06
Upf1 and Upf2 proteins mediate normal yeast mRNA degradation when translation initiation is limited. Nucleic Acids Res (1998) 1.02
A turnover pathway for both stable and unstable mRNAs in yeast: evidence for a requirement for deadenylation. Genes Dev (1993) 9.28
A rapid method for localized mutagenesis of yeast genes. Yeast (1992) 7.79
Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript. Genes Dev (1994) 7.57
Degradation of mRNA in eukaryotes. Cell (1995) 6.81
An essential component of the decapping enzyme required for normal rates of mRNA turnover. Nature (1996) 6.15
Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA. Cell (1987) 6.08
Premature translational termination triggers mRNA decapping. Nature (1994) 6.05
Yeast Sm-like proteins function in mRNA decapping and decay. Nature (2000) 5.95
The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell (2001) 5.86
Turnover mechanisms of the stable yeast PGK1 mRNA. Mol Cell Biol (1995) 5.83
Identification and comparison of stable and unstable mRNAs in Saccharomyces cerevisiae. Mol Cell Biol (1990) 5.47
The DCP2 protein is required for mRNA decapping in Saccharomyces cerevisiae and contains a functional MutT motif. EMBO J (1999) 5.08
The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA (2001) 4.80
Yeast exosome mutants accumulate 3'-extended polyadenylated forms of U4 small nuclear RNA and small nucleolar RNAs. Mol Cell Biol (2000) 4.57
Mechanisms and control of mRNA turnover in Saccharomyces cerevisiae. Microbiol Rev (1996) 4.34
Mutations affecting stability and deadenylation of the yeast MFA2 transcript. Genes Dev (1992) 4.20
Multiple functions for the poly(A)-binding protein in mRNA decapping and deadenylation in yeast. Genes Dev (1995) 4.15
Targeting an mRNA for decapping: displacement of translation factors and association of the Lsm1p-7p complex on deadenylated yeast mRNAs. Mol Cell (2001) 4.12
A small segment of the MAT alpha 1 transcript promotes mRNA decay in Saccharomyces cerevisiae: a stimulatory role for rare codons. Mol Cell Biol (1993) 3.91
Quality control of mRNA 3'-end processing is linked to the nuclear exosome. Nature (2001) 3.69
Mutations in trans-acting factors affecting mRNA decapping in Saccharomyces cerevisiae. Mol Cell Biol (1996) 3.58
The Puf3 protein is a transcript-specific regulator of mRNA degradation in yeast. EMBO J (2000) 3.38
Differential effects of translational inhibition in cis and in trans on the decay of the unstable yeast MFA2 mRNA. J Biol Chem (1994) 3.37
Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome. EMBO J (1986) 3.35
mRNA decapping in yeast requires dissociation of the cap binding protein, eukaryotic translation initiation factor 4E. Mol Cell Biol (2000) 3.06
Mechanisms of mRNA degradation in eukaryotes. Trends Biochem Sci (1994) 2.96
Survival with the acquired immunodeficiency syndrome. Experience with 5833 cases in New York City. N Engl J Med (1987) 2.91
Isolation and characterization of Dcp1p, the yeast mRNA decapping enzyme. EMBO J (1998) 2.82
Mechanisms of mRNA surveillance in eukaryotes. Annu Rev Genet (1999) 2.73
The exosome: a proteasome for RNA? Cell (1999) 2.72
Function of the ski4p (Csl4p) and Ski7p proteins in 3'-to-5' degradation of mRNA. Mol Cell Biol (2000) 2.71
Prevention of premature birth by screening and treatment for common genital tract infections: results of a prospective controlled evaluation. Am J Obstet Gynecol (1995) 2.69
Oxaliplatin, tetraplatin, cisplatin, and carboplatin: spectrum of activity in drug-resistant cell lines and in the cell lines of the National Cancer Institute's Anticancer Drug Screen panel. Biochem Pharmacol (1996) 2.67
Mechanisms and control of mRNA decapping in Saccharomyces cerevisiae. Annu Rev Biochem (2000) 2.66
Changes in tonsillectomy rates associated with feedback and review. Pediatrics (1977) 2.60
A point mutation in the conserved hexanucleotide at a yeast 5' splice junction uncouples recognition, cleavage, and ligation. Cell (1985) 2.56
The UK colorectal cancer screening pilot: results of the second round of screening in England. Br J Cancer (2007) 2.48
Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J (2000) 2.44
Analysis of the yeast genome: identification of new non-coding and small ORF-containing RNAs. Nucleic Acids Res (1997) 2.40
Measurement of mRNA decay rates in Saccharomyces cerevisiae. Methods Enzymol (1991) 2.17
Aberrant mRNAs with extended 3' UTRs are substrates for rapid degradation by mRNA surveillance. RNA (1999) 2.15
Functions of Lsm proteins in mRNA degradation and splicing. Curr Opin Cell Biol (2000) 2.14
Diversity of cytoplasmic functions for the 3' untranslated region of eukaryotic transcripts. Curr Opin Cell Biol (1995) 2.06
A trans-acting suppressor restores splicing of a yeast intron with a branch point mutation. Genes Dev (1987) 1.99
Chemotherapy plus local treatment in the management of intraocular retinoblastoma. Arch Ophthalmol (1996) 1.95
Analysis of mutations in the yeast mRNA decapping enzyme. Genetics (1999) 1.93
mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization? RNA (1999) 1.89
Recognition of yeast mRNAs as "nonsense containing" leads to both inhibition of mRNA translation and mRNA degradation: implications for the control of mRNA decapping. Mol Biol Cell (1999) 1.88
Functional evaluation following microvascular oromandibular reconstruction of the oral cancer patient: a comparative study of reconstructed and nonreconstructed patients. Laryngoscope (1991) 1.85
Separation of the mixture of trehalose 6,6'-dimycolates comprising the mycobacterial glycolipid fraction, "P3". Biochem Biophys Res Commun (1977) 1.82
Two related proteins, Edc1p and Edc2p, stimulate mRNA decapping in Saccharomyces cerevisiae. Genetics (2001) 1.80
Computational modeling of eukaryotic mRNA turnover. RNA (2001) 1.79
The conversion of 4-hydroxypyrazolo[3,4-d]pyrimidine (allopurinol) into 4,6-dihroxypyrazolo[3,4-d]pyrimidine (Oxipurinol) in vivo in the absence of xanthine-oxen oxidoreductase. Biochem J (1969) 1.76
Defects in the mRNA export factors Rat7p, Gle1p, Mex67p, and Rat8p cause hyperadenylation during 3'-end formation of nascent transcripts. RNA (2001) 1.71
Detection of Trichomonas vaginalis in pregnant women with the InPouch TV culture system. J Clin Microbiol (1993) 1.68
Time trends in incidence rates of first hip fracture in the Uppsala Health Care Region, Sweden, 1965-1983. Am J Epidemiol (1989) 1.62
The medical management of a heroin epidemic. Arch Gen Psychiatry (1972) 1.59
The yeast cytoplasmic LsmI/Pat1p complex protects mRNA 3' termini from partial degradation. Genetics (2001) 1.57
Bacterial vaginosis is associated with prematurity and vaginal fluid mucinase and sialidase: results of a controlled trial of topical clindamycin cream. Am J Obstet Gynecol (1994) 1.57
Performance measures in three rounds of the English bowel cancer screening pilot. Gut (2011) 1.52
Analysis of chimeric mRNAs derived from the STE3 mRNA identifies multiple regions within yeast mRNAs that modulate mRNA decay. Nucleic Acids Res (1992) 1.51
Epidemiologic features of Strongyloides stercoralis infection in an endemic area of the United States. Am J Trop Med Hyg (1982) 1.49
Local impact of the English arm of the UK Bowel Cancer Screening Pilot study. Br J Surg (2008) 1.42
Ritualised self harm in traditional aboriginal society. Aust N Z J Psychiatry (1994) 1.39
Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines. Mol Cell Biol (1992) 1.39
Postoperative radiation therapy after radical prostatectomy for prostate carcinoma. Cancer (1992) 1.38
Orientation-dependent function of a short CYC1 DNA fragment in directing mRNA 3' end formation in yeast. Proc Natl Acad Sci U S A (1988) 1.32
mRNA turnover in yeast promoted by the MATalpha1 instability element. Nucleic Acids Res (1996) 1.26
A multivariate analysis of factors associated with depression: evaluating the role of health literacy as a potential contributor. Arch Intern Med (2000) 1.26
Ability, achievement, and adjustment in homeless children. Am J Orthopsychiatry (1991) 1.25
A demonstration pilot trial for colorectal cancer screening in the United Kingdom: a new concept in the introduction of healthcare strategies. J Med Screen (2001) 1.25
Modelling potential impacts of bottom trawl fisheries on soft sediment biogeochemistry in the North Sea. Geochem Trans (2001) 1.21
Effects of mutations in the Saccharomyces cerevisiae RNA14, RNA15, and PAP1 genes on polyadenylation in vivo. Mol Cell Biol (1995) 1.20
Biologically active components from mycobacterial cell walls. IV. Protection of mice against aerosol infection with virulent mycobacterium tuberculosis. Cell Immunol (1975) 1.20
Surgical management of ventricular tachycardia in subannular left ventricular aneurysm. Ann Thorac Surg (1995) 1.16
Simplified scoring and psychometrics of the revised 12-item Short-Form Health Survey. Outcomes Manag Nurs Pract (2002) 1.14
TGF-beta in intestinal lymphoid organs contributes to the death of armed effector CD8 T cells and is associated with the absence of virus containment in rhesus macaques infected with the simian immunodeficiency virus. Cell Death Differ (2007) 1.14
Computational identification of cis-acting elements affecting post-transcriptional control of gene expression in Saccharomyces cerevisiae. Nucleic Acids Res (2000) 1.14
A stochastic and deterministic model of medical care utilization. Health Serv Res (1970) 1.10
Effect of water as a diluent on the glass transition behaviour of malto-oligosaccharides, amylose and amylopectin. Int J Biol Macromol (1989) 1.08
RNA turnover: the helicase story unwinds. Curr Biol (1996) 1.08
Sexual practices and attitudes of street youth in Belo Horizonte, Brazil. Street Youth Study Group. Soc Sci Med (1993) 1.07
Moieties of mycobacterial mycolates required for inducing granulomatous reactions. Cell Immunol (1978) 1.06
An adult formulation of a five-component acellular pertussis vaccine combined with diphtheria and tetanus toxoids is safe and immunogenic in adolescents and adults. Vaccine (2000) 1.05
Activation of a cryptic TACTAAC box in the Saccharomyces cerevisiae actin intron. Mol Cell Biol (1986) 1.05
Tn3 encodes a site-specific recombination system: identification of essential sequences, genes, and the actual site of recombination. Cold Spring Harb Symp Quant Biol (1981) 1.04
The effect of allograft meniscal replacement on intraarticular contact area and pressures in the human knee. A biomechanical study. Am J Sports Med (1997) 1.03
A comparison of a discriminant versus a clustering analysis of a patient classification for chronic disease care. Med Care (1974) 1.03
Clindamycin vaginal cream versus oral metronidazole in the treatment of bacterial vaginosis: a prospective double-blind clinical trial. South Med J (1992) 1.03
The quantitative determination of hypoxanthine and xanthine ("oxypurines") in skeletal muscle from two patients with congenital xanthine oxidase deficiency (xanthinuria). Biochem J (1970) 1.03
Aortic cannulation. Thorax (1969) 1.02
Preservation of isolated heart for 72 hours. Br Med J (1968) 1.02
Advancing newborn health: The Saving Newborn Lives initiative. Glob Public Health (2010) 1.00
Effect of cimetidine and other antihistaminics on the elimination of aminopyrine, phenacetin and caffeine. Life Sci (1980) 1.00
Optimal management of amiodarone therapy: efficacy and side effects. Pharmacotherapy (1999) 0.99
Induction of resistance to tuberculosis in mice with defined components of mycobacteria and with some unrelated materials. Immunology (1982) 0.98
European vestibular experiments on the Spacelab-1 mission: 3. Caloric nystagmus in microgravity. Exp Brain Res (1986) 0.96
Yeast mRNA decapping enzyme. Methods Enzymol (2001) 0.95