Published in J Cell Biol on November 29, 1999
A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A (2005) 3.62
PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases. Mol Cell Biol (2002) 3.25
Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1). Proc Natl Acad Sci U S A (2000) 2.79
Septins: the fourth component of the cytoskeleton. Nat Rev Mol Cell Biol (2012) 2.77
Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1. EMBO J (2005) 2.54
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Mol Cell Proteomics (2010) 2.43
Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. J Cell Biol (2004) 2.42
Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stresses. J Biol Chem (2004) 2.27
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes Dev (2006) 2.15
Septin structure and function in yeast and beyond. Trends Cell Biol (2010) 1.99
The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity. J Cell Biol (2003) 1.97
Some assembly required: yeast septins provide the instruction manual. Trends Cell Biol (2005) 1.96
Genes involved in sister chromatid separation and segregation in the budding yeast Saccharomyces cerevisiae. Genetics (2001) 1.89
Sporulation in the budding yeast Saccharomyces cerevisiae. Genetics (2011) 1.88
Cell cycle-dependent assembly of a Gin4-septin complex. Mol Biol Cell (2002) 1.83
MAPL is a new mitochondrial SUMO E3 ligase that regulates mitochondrial fission. EMBO Rep (2009) 1.80
Genetic analysis of SUMOylation in Arabidopsis: conjugation of SUMO1 and SUMO2 to nuclear proteins is essential. Plant Physiol (2007) 1.79
Gene expression patterns associated with blood-feeding in the malaria mosquito Anopheles gambiae. BMC Genomics (2005) 1.73
Comparison of SUMO fusion technology with traditional gene fusion systems: enhanced expression and solubility with SUMO. Protein Sci (2005) 1.73
Small ubiquitin-like modifier modulates abscisic acid signaling in Arabidopsis. Plant Cell (2003) 1.70
Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements. PLoS Genet (2013) 1.67
Here come the septins: novel polymers that coordinate intracellular functions and organization. J Cell Sci (2006) 1.60
The septins. Genome Biol (2003) 1.58
SUMO: regulating the regulator. Cell Div (2006) 1.56
Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p. Eukaryot Cell (2003) 1.52
Emerging roles of the SUMO pathway in mitosis. Cell Div (2008) 1.48
Ikaros SUMOylation: switching out of repression. Mol Cell Biol (2005) 1.48
Structure of the Siz/PIAS SUMO E3 ligase Siz1 and determinants required for SUMO modification of PCNA. Mol Cell (2009) 1.46
Cell polarization and cytokinesis in budding yeast. Genetics (2012) 1.45
SUMOylation of the mitochondrial fission protein Drp1 occurs at multiple nonconsensus sites within the B domain and is linked to its activity cycle. FASEB J (2009) 1.45
SUMO regulates the assembly and function of a cytoplasmic intermediate filament protein in C. elegans. Dev Cell (2009) 1.43
Septins: molecular partitioning and the generation of cellular asymmetry. Cell Div (2009) 1.42
Septin function in yeast model systems and pathogenic fungi. Eukaryot Cell (2005) 1.41
SUMO modification regulates inactivation of the voltage-gated potassium channel Kv1.5. Proc Natl Acad Sci U S A (2007) 1.39
Mid2p stabilizes septin rings during cytokinesis in fission yeast. J Cell Biol (2003) 1.37
Misregulation of 2 microm circle copy number in a SUMO pathway mutant. Mol Cell Biol (2005) 1.36
Sumoylation of the budding yeast kinetochore protein Ndc10 is required for Ndc10 spindle localization and regulation of anaphase spindle elongation. J Cell Biol (2006) 1.34
Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor. Biochem J (2002) 1.33
SIZ1/SIZ2 control of chromosome transmission fidelity is mediated by the sumoylation of topoisomerase II. Genetics (2005) 1.30
Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9. J Virol (2001) 1.28
Septin stability and recycling during dynamic structural transitions in cell division and development. Curr Biol (2008) 1.27
The yeast nuclear pore complex and transport through it. Genetics (2012) 1.26
Quality control of a transcriptional regulator by SUMO-targeted degradation. Mol Cell Biol (2009) 1.25
The role of karyopherins in the regulated sumoylation of septins. J Cell Biol (2007) 1.22
One SUMO is sufficient to silence the dimeric potassium channel K2P1. Proc Natl Acad Sci U S A (2010) 1.22
SUMO modification of Rad22, the Schizosaccharomyces pombe homologue of the recombination protein Rad52. Nucleic Acids Res (2001) 1.20
The small ubiquitin-like modifier (SUMO) is required for gonadal and uterine-vulval morphogenesis in Caenorhabditis elegans. Genes Dev (2004) 1.20
Positive and negative regulation of APP amyloidogenesis by sumoylation. Proc Natl Acad Sci U S A (2002) 1.20
Genes adopt non-optimal codon usage to generate cell cycle-dependent oscillations in protein levels. Mol Syst Biol (2012) 1.19
Improved identification of SUMO attachment sites using C-terminal SUMO mutants and tailored protease digestion strategies. J Proteome Res (2006) 1.14
Stimulation of in vitro sumoylation by Slx5-Slx8: evidence for a functional interaction with the SUMO pathway. DNA Repair (Amst) (2007) 1.14
Regulation of distinct septin rings in a single cell by Elm1p and Gin4p kinases. Mol Biol Cell (2009) 1.13
Mitochondria and the culture of the Borg: understanding the integration of mitochondrial function within the reticulum, the cell, and the organism. Bioessays (2010) 1.12
Sumoylation and regulation of cardiac gene expression. Circ Res (2010) 1.08
Shs1 plays separable roles in septin organization and cytokinesis in Saccharomyces cerevisiae. Genetics (2007) 1.08
Functional characterization of Dma1 and Dma2, the budding yeast homologues of Schizosaccharomyces pombe Dma1 and human Chfr. Mol Biol Cell (2004) 1.08
A draft of the human septin interactome. PLoS One (2010) 1.06
Topoisomerase I-dependent viability loss in saccharomyces cerevisiae mutants defective in both SUMO conjugation and DNA repair. Genetics (2007) 1.05
Cell cycle programs of gene expression control morphogenetic protein localization. J Cell Biol (2000) 1.04
Suppression of TGFβ-induced epithelial-mesenchymal transition like phenotype by a PIAS1 regulated sumoylation pathway in NMuMG epithelial cells. PLoS One (2010) 1.04
The 2 microm plasmid causes cell death in Saccharomyces cerevisiae with a mutation in Ulp1 protease. Mol Cell Biol (2005) 1.00
Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast. Cell Cycle (2009) 1.00
Sumoylation of the BLM ortholog, Sgs1, promotes telomere-telomere recombination in budding yeast. Nucleic Acids Res (2009) 0.98
Cytokinesis in yeast meiosis depends on the regulated removal of Ssp1p from the prospore membrane. EMBO J (2007) 0.98
In vivo modeling of polysumoylation uncovers targeting of Topoisomerase II to the nucleolus via optimal level of SUMO modification. Chromosoma (2007) 0.97
Pervasive and essential roles of the Top3-Rmi1 decatenase orchestrate recombination and facilitate chromosome segregation in meiosis. Mol Cell (2015) 0.97
Posttranslational modifications of proteins in the pathobiology of medically relevant fungi. Eukaryot Cell (2011) 0.96
In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice. Proc Natl Acad Sci U S A (2012) 0.95
SUMOylation-Mediated Regulation of Cell Cycle Progression and Cancer. Trends Biochem Sci (2015) 0.95
Specific interaction with cardiolipin triggers functional activation of Dynamin-Related Protein 1. PLoS One (2014) 0.94
Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans. Mol Biol Cell (2011) 0.94
Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function. Nucleic Acids Res (2003) 0.92
Nuclear import is required for the pro-apoptotic function of the Golgi protein p115. J Biol Chem (2008) 0.92
A role for SUMO in nucleotide excision repair. DNA Repair (Amst) (2011) 0.92
A novel role for the CBF3 kinetochore-scaffold complex in regulating septin dynamics and cytokinesis. J Cell Biol (2005) 0.92
Functional interaction between human herpesvirus 6 immediate-early 2 protein and ubiquitin-conjugating enzyme 9 in the absence of sumoylation. J Virol (2006) 0.92
Septin ring size scaling and dynamics require the coiled-coil region of Shs1p. Mol Biol Cell (2012) 0.91
Ras1 interacts with multiple new signaling and cytoskeletal loci in Drosophila eggshell patterning and morphogenesis. Genetics (2001) 0.91
Deficient SUMO attachment to Flp recombinase leads to homologous recombination-dependent hyperamplification of the yeast 2 microm circle plasmid. Mol Biol Cell (2008) 0.91
Regulation of septin dynamics by the Saccharomyces cerevisiae lysine acetyltransferase NuA4. PLoS One (2011) 0.90
Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress. Mol Cell Biol (2006) 0.90
UBC9 autosumoylation negatively regulates sumoylation of septins in Saccharomyces cerevisiae. J Biol Chem (2011) 0.90
Septins are important for cell polarity, septation and asexual spore formation in Neurospora crassa and show different patterns of localisation at germ tube tips. PLoS One (2013) 0.90
Sumo and the cellular stress response. Cell Div (2015) 0.89
Crystal structure of UBA2(ufd)-Ubc9: insights into E1-E2 interactions in Sumo pathways. PLoS One (2010) 0.89
Sumoylation of Rap1 mediates the recruitment of TFIID to promote transcription of ribosomal protein genes. Genome Res (2015) 0.89
SUMO-1 represses apoptosis signal-regulating kinase 1 activation through physical interaction and not through covalent modification. EMBO Rep (2005) 0.89
SUMOylation regulates the SNF1 protein kinase. Proc Natl Acad Sci U S A (2013) 0.89
SUMO modification of DNA topoisomerase II: trying to get a CENse of it all. DNA Repair (Amst) (2009) 0.89
Specific domain structures control abscisic acid-, salicylic acid-, and stress-mediated SIZ1 phenotypes. Plant Physiol (2009) 0.88
Dma/RNF8 proteins are evolutionarily conserved E3 ubiquitin ligases that target septins. Cell Cycle (2013) 0.87
Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol (2011) 0.87
A SUMO-targeted ubiquitin ligase is involved in the degradation of the nuclear pool of the SUMO E3 ligase Siz1. Mol Biol Cell (2013) 0.87
Sumo-dependent substrate targeting of the SUMO protease Ulp1. BMC Biol (2011) 0.85
SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis elegans dosage compensation complex on X chromosomes. Proc Natl Acad Sci U S A (2013) 0.85
Desumoylation of the endoplasmic reticulum membrane VAP family protein Scs2 by Ulp1 and SUMO regulation of the inositol synthesis pathway. Mol Cell Biol (2011) 0.85
Cardiac function and disease: emerging role of small ubiquitin-related modifier. Wiley Interdiscip Rev Syst Biol Med (2010) 0.85
An improved SUMmOn-based methodology for the identification of ubiquitin and ubiquitin-like protein conjugation sites identifies novel ubiquitin-like protein chain linkages. Proteomics (2010) 0.85
Asymmetric cell division in polyploid giant cancer cells and low eukaryotic cells. Biomed Res Int (2014) 0.84
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