Published in Proc Natl Acad Sci U S A on February 29, 2000
A sensitized genetic screen to identify novel regulators and components of the Drosophila janus kinase/signal transducer and activator of transcription pathway. Genetics (2003) 1.63
Notch signaling regulates growth and differentiation in the mammalian lens. Dev Biol (2008) 1.29
Conservation of Pax 6 function and upstream activation by Notch signaling in eye development of frogs and flies. Proc Natl Acad Sci U S A (2002) 1.15
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Transcriptional activities of the Pax6 gene eyeless regulate tissue specificity of ectopic eye formation in Drosophila. Dev Biol (2009) 0.88
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The retinal determination gene eyes absent is regulated by the EGF receptor pathway throughout development in Drosophila. Genetics (2009) 0.87
Identification of retinal transformation hot spots in developing Drosophila epithelia. PLoS One (2010) 0.87
Position dependent responses to discontinuities in the retinal determination network. Dev Biol (2008) 0.86
Hrp48 attenuates Sxl expression to allow for proper notch expression and signaling in wing development. Proc Natl Acad Sci U S A (2010) 0.84
Transformation of eye to antenna by misexpression of a single gene. Mech Dev (2007) 0.83
Misexpression screen in Drosophila melanogaster aiming to reveal novel factors involved in formation of body parts. Genetics (2006) 0.82
The transcriptional co-factor Chip acts with LIM-homeodomain proteins to set the boundary of the eye field in Drosophila. Development (2010) 0.81
The Drosophila Pax6 paralogs have different functions in head development but can partially substitute for each other. Mol Genet Genomics (2009) 0.81
Gain of function notch phenotypes associated with ectopic expression of the Su(H) C-terminal domain illustrate separability of Notch and hairless-mediated activities. PLoS One (2013) 0.80
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The Eye Specification Network in Drosophila. Proc Indian Natl Sci Acad B Biol Sci (2004) 0.77
Expression of mutant CHMP2B, an ESCRT-III component involved in frontotemporal dementia, causes eye deformities due to Notch misregulation in Drosophila. FASEB J (2013) 0.76
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The master control gene for morphogenesis and evolution of the eye. Genes Cells (1996) 1.73
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Dorsal-ventral signaling in the Drosophila eye. Science (1998) 1.40
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Functional analysis of an eye specific enhancer of the eyeless gene in Drosophila. Proc Natl Acad Sci U S A (1999) 1.37
Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila. Development (1997) 1.37
Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb. Nature (1997) 1.33
The homeobox gene Distal-less induces ventral appendage development in Drosophila. Genes Dev (1997) 1.31
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Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. Science (1995) 7.35
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Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats. Cell (1985) 6.93
A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes. Nature (1984) 6.62
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Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science (1994) 5.75
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Translational and transcriptional control elements in the untranslated leader of the heat-shock gene hsp22. Cell (1986) 5.00
A homologous protein-coding sequence in Drosophila homeotic genes and its conservation in other metazoans. Cell (1984) 4.95
The white gene as a marker in a new P-element vector for gene transfer in Drosophila. Nucleic Acids Res (1987) 4.92
Control elements of the Drosophila segmentation gene fushi tarazu. Cell (1985) 4.83
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor. Cell (1991) 4.37
Fly and frog homoeo domains show homologies with yeast mating type regulatory proteins. Nature (1984) 4.33
The structure of the Antennapedia homeodomain determined by NMR spectroscopy in solution: comparison with prokaryotic repressors. Cell (1989) 4.13
Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila. Cell (1990) 4.07
Regulation and function of the Drosophila segmentation gene fushi tarazu. Cell (1987) 3.91
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat Genet (2000) 3.82
The suppressor of hairless protein participates in notch receptor signaling. Cell (1994) 3.81
Contact-dependent inhibition of cortical neurite growth mediated by notch signaling. Science (1999) 3.74
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Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell (1997) 3.47
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P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila. Genes Dev (1989) 3.45
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Alterations in Notch signaling in neoplastic lesions of the human cervix. Proc Natl Acad Sci U S A (1995) 3.33
Calcium depletion dissociates and activates heterodimeric notch receptors. Mol Cell Biol (2000) 3.15
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Spatial distribution of transcripts from the segmentation gene fushi tarazu during Drosophila embryonic development. Cell (1984) 2.72
Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins. Nat Genet (1992) 2.71
Processing of the notch ligand delta by the metalloprotease Kuzbanian. Science (1999) 2.71
The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae. J Cell Biol (1995) 2.69
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Isolation and sequence-specific DNA binding of the Antennapedia homeodomain. EMBO J (1988) 2.57
Eyeless initiates the expression of both sine oculis and eyes absent during Drosophila compound eye development. Development (1998) 2.56
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The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells. Blood (1998) 2.05
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