Published in Nature on February 17, 2000
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Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A (2003) 7.60
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Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta. J Cell Biochem (2005) 1.18
Smad signaling in skeletal development and regeneration. Cytokine Growth Factor Rev (2009) 1.17
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Tumour-stroma interactions in colorectal cancer: converging on beta-catenin activation and cancer stemness. Br J Cancer (2008) 1.13
Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer. Epigenetics (2013) 1.13
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TGF-β regulates β-catenin signaling and osteoblast differentiation in human mesenchymal stem cells. J Cell Biochem (2011) 1.11
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Inhibition of Wnt/Axin/beta-catenin pathway activity promotes ventral CNS midline tissue to adopt hypothalamic rather than floorplate identity. Development (2004) 0.98
Mad is required for wingless signaling in wing development and segment patterning in Drosophila. PLoS One (2009) 0.97
Antagonistic effect of the matricellular signaling protein CCN3 on TGF-beta- and Wnt-mediated fibrillinogenesis in systemic sclerosis and Marfan syndrome. J Invest Dermatol (2010) 0.97
Requirement of TCF7L2 for TGF-beta-dependent transcriptional activation of the TMEPAI gene. J Biol Chem (2010) 0.96
Phosphorylation of Mad controls competition between wingless and BMP signaling. Sci Signal (2011) 0.95
DACH1, a zona glomerulosa selective gene in the human adrenal, activates transforming growth factor-β signaling and suppresses aldosterone secretion. Hypertension (2015) 0.95
Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials (2014) 0.94
Expression of Siamois and Twin in the blastula Chordin/Noggin signaling center is required for brain formation in Xenopus laevis embryos. Mech Dev (2007) 0.93
Prognostic significance of BMP and activin membrane-bound inhibitor in colorectal cancer. World J Gastroenterol (2008) 0.93
Cloning and developmental expression of mouse pygopus 2, a putative Wnt signaling component. Genomics (2004) 0.93
A Wnt-TGFβ2 axis induces a fibrogenic program in muscle stem cells from dystrophic mice. Sci Transl Med (2014) 0.92
Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity. EMBO J (2011) 0.92
Controversy surrounding the increased expression of TGF beta 1 in asthma. Respir Res (2007) 0.92
β-Catenin-independent activation of TCF1/LEF1 in human hematopoietic tumor cells through interaction with ATF2 transcription factors. PLoS Genet (2013) 0.91
The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: implications in targeted cancer therapies. Lab Invest (2015) 0.91
Siamois and Twin are redundant and essential in formation of the Spemann organizer. Dev Biol (2011) 0.90
Canonical Wnt signalling requires the BMP pathway to inhibit oligodendrocyte maturation. ASN Neuro (2011) 0.87
Wnt/β-catenin pathway regulates bone morphogenetic protein (BMP2)-mediated differentiation of dental follicle cells. J Periodontal Res (2011) 0.86
Inhibition of Drosophila Wg signaling involves competition between Mad and Armadillo/beta-catenin for dTcf binding. PLoS One (2008) 0.86
Complexity in interpretation of embryonic epithelial-mesenchymal transition in response to transforming growth factor-beta signaling. Cells Tissues Organs (2007) 0.85
An arrayed RNA interference genome-wide screen identifies candidate genes involved in the MicroRNA 21 biogenesis pathway. Assay Drug Dev Technol (2012) 0.85
Modulation of β-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci (2013) 0.85
Concise review: breast cancer stem cells: regulatory networks, stem cell niches, and disease relevance. Stem Cells Transl Med (2014) 0.83
Wg signaling via Zw3 and mad restricts self-renewal of sensory organ precursor cells in Drosophila. Genetics (2011) 0.83
Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression. Nucleic Acids Res (2012) 0.83
Evolutionary rewiring of gene regulatory network linkages at divergence of the echinoid subclasses. Proc Natl Acad Sci U S A (2015) 0.82
Maintenance of a normal thymic microenvironment and T-cell homeostasis require Smad4-mediated signaling in thymic epithelial cells. Blood (2008) 0.82
Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin. J Cell Sci (2013) 0.81
Identification of DNA-dependent protein kinase catalytic subunit as a novel interaction partner of lymphocyte enhancer factor 1. Med Mol Morphol (2013) 0.80
Uncoupled responses of Smad4-deficient cancer cells to TNFalpha result in secretion of monomeric laminin-gamma2. Mol Cancer (2010) 0.80
Connective tissue disease: SSc-fibrosis takes flight with Wingless inhibition. Nat Rev Rheumatol (2012) 0.79
The human disease network in terms of dysfunctional regulatory mechanisms. Biol Direct (2015) 0.79
Downregulation of the Canonical WNT Signaling Pathway by TGFβ1 Inhibits Photoreceptor Differentiation of Adult Human Müller Glia with Stem Cell Characteristics. Stem Cells Dev (2015) 0.78
Pigment epithelium-derived factor attenuates myocardial fibrosis via inhibiting Endothelial-to-Mesenchymal Transition in rats with acute myocardial infarction. Sci Rep (2017) 0.78
A novel microRNA located in TrkC gene regulates Wnt signaling pathway and is differentially expressed in colorectal cancer specimens. J Biol Chem (2017) 0.78
Gene expression profiling in mouse liver infected with Clonorchis sinensis metacercariae. Parasitol Res (2009) 0.77
Both ciliary and non-ciliary functions of Foxj1a confer Wnt/β-catenin signaling in zebrafish left-right patterning. Biol Open (2015) 0.77
Quantitative proteomics identify DAB2 as a cardiac developmental regulator that inhibits WNT/β-catenin signaling. Proc Natl Acad Sci U S A (2016) 0.77
Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer. Gastroenterology (2016) 0.77
Wnt and BMP Signaling Crosstalk in Regulating Dental Stem Cells: Implications in Dental Tissue Engineering. Genes Dis (2016) 0.76
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