Hsp72 functions as a natural inhibitory protein of c-Jun N-terminal kinase.

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Published in EMBO J on February 01, 2001

Authors

H S Park1, J S Lee, S H Huh, J S Seo, E J Choi

Author Affiliations

1: National Creative Research Initiative Center for Cell Death, Graduate School of Biotechnology, Korea University, Seoul 136-701 Korea.

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Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly. Science (1990) 5.88

Peptide binding and release by proteins implicated as catalysts of protein assembly. Science (1989) 5.84

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Parallel signal processing among mammalian MAPKs. Trends Biochem Sci (1995) 4.46

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