Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression.

PubWeight™: 1.60‹?› | Rank: Top 4%

🔗 View Article (PMID 11544477)

Published in Nat Genet on October 01, 2001

Authors

Z Herceg1, W Hulla, D Gell, C Cuenin, M Lleonart, S Jackson, Z Q Wang

Author Affiliations

1: International Agency for Research on Cancer (IARC), 150 Cours Albert Thomas, F-69008, Lyon, France.

Articles citing this

Exome sequencing identifies GRIN2A as frequently mutated in melanoma. Nat Genet (2011) 7.31

Chromatin remodelling during development. Nature (2010) 5.86

An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell (2008) 4.27

Open chromatin in pluripotency and reprogramming. Nat Rev Mol Cell Biol (2011) 2.69

Genes and pathways driving glioblastomas in humans and murine disease models. Neurosurg Rev (2003) 2.32

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance. Mol Cell (2009) 2.29

Chromatin modifiers and remodellers: regulators of cellular differentiation. Nat Rev Genet (2013) 1.98

Chromatin regulatory mechanisms in pluripotency. Annu Rev Cell Dev Biol (2010) 1.51

A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex. Am J Hum Genet (2016) 1.41

Identification of Drosophila mitotic genes by combining co-expression analysis and RNA interference. PLoS Genet (2008) 1.41

Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks. EMBO J (2006) 1.36

MRG15 regulates embryonic development and cell proliferation. Mol Cell Biol (2005) 1.35

The histone H3 acetylase dGcn5 is a key player in Drosophila melanogaster metamorphosis. Mol Cell Biol (2005) 1.30

The high-mobility-group box protein SSRP1/T160 is essential for cell viability in day 3.5 mouse embryos. Mol Cell Biol (2003) 1.21

Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition. Mol Cell Biol (2007) 1.13

Homozygous disruption of the Tip60 gene causes early embryonic lethality. Dev Dyn (2009) 1.12

TAF10 (TAF(II)30) is necessary for TFIID stability and early embryogenesis in mice. Mol Cell Biol (2003) 1.11

Chromatin as an oxygen sensor and active player in the hypoxia response. Cell Signal (2011) 1.05

Mammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression. J Biol Chem (2012) 1.03

Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes. Mol Cell Biol (2010) 1.01

The transcriptional histone acetyltransferase cofactor TRRAP associates with the MRN repair complex and plays a role in DNA double-strand break repair. Mol Cell Biol (2006) 1.01

Integrated regulation of PIKK-mediated stress responses by AAA+ proteins RUVBL1 and RUVBL2. Nucleus (2012) 0.94

HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression. EMBO J (2004) 0.93

Structure/function analysis of the phosphatidylinositol-3-kinase domain of yeast tra1. Genetics (2007) 0.90

Essential role of p400/mDomino chromatin-remodeling ATPase in bone marrow hematopoiesis and cell-cycle progression. J Biol Chem (2010) 0.88

Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex. EMBO J (2011) 0.88

Distinct roles of DMAP1 in mouse development. Mol Cell Biol (2011) 0.88

Genome-wide analysis of gene expression regulated by the HAT cofactor Trrap in conditional knockout cells. Nucleic Acids Res (2003) 0.87

Histological and transcriptome-wide level characteristics of fetal myofiber hyperplasia during the second half of gestation in Texel and Ujumqin sheep. BMC Genomics (2011) 0.86

Role of ZBP-89 in human globin gene regulation and erythroid differentiation. Blood (2011) 0.84

Mutational analysis of the C-terminal FATC domain of Saccharomyces cerevisiae Tra1. Curr Genet (2010) 0.84

Chromatin-remodeling complex specificity and embryonic vascular development. Cell Mol Life Sci (2012) 0.80

SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells. Epigenetics (2014) 0.79

Epigenetics of pluripotent cells. Acta Naturae (2012) 0.78

The chromatin regulator DMAP1 modulates activity of the nuclear factor B (NF-B) transcription factor Relish in the Drosophila innate immune response. J Biol Chem (2014) 0.77

Lysine Acetylation and Deacetylation in Brain Development and Neuropathies. Genomics Proteomics Bioinformatics (2017) 0.75

Transient Shifts of Incubation Temperature Reveal Immediate and Long-Term Transcriptional Response in Chicken Breast Muscle Underpinning Resilience and Phenotypic Plasticity. PLoS One (2016) 0.75

Ataxia telangiectasia mutated (ATM) interacts with p400 ATPase for an efficient DNA damage response. BMC Mol Biol (2016) 0.75

KATapulting toward Pluripotency and Cancer. J Mol Biol (2016) 0.75

Tissue-specific inactivation of HAT cofactor TRRAP reveals its essential role in B cells. Cell Cycle (2014) 0.75

Articles by these authors

(truncated to the top 100)

Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature (1999) 23.62

c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling. Science (1994) 5.97

Prevention of falls in the elderly trial (PROFET): a randomised controlled trial. Lancet (1999) 5.37

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product. Cell (1995) 4.64

Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med (1997) 4.57

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia. Nat Med (1997) 4.12

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell (1994) 3.91

Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature (1996) 3.83

DNA looping between sites for transcriptional activation: self-association of DNA-bound Sp1. Genes Dev (1991) 3.10

Subtypes of human immunodeficiency virus type 1 and disease stage among women in Nairobi, Kenya. J Virol (1999) 2.90

Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol (2001) 2.85

Health effects of caregiving: the caregiver health effects study: an ancillary study of the Cardiovascular Health Study. Ann Behav Med (1997) 2.79

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse. Proc Natl Acad Sci U S A (1996) 2.77

A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. Science (1999) 2.68

Immunological and virological analyses of persons infected by human immunodeficiency virus type 1 while participating in trials of recombinant gp120 subunit vaccines. J Virol (1998) 2.63

Nitric oxide: a key mediator in the early and late phase of carrageenan-induced rat paw inflammation. Br J Pharmacol (1996) 2.55

Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity. Immunity (1998) 2.43

Effect of Towne live virus vaccine on cytomegalovirus disease after renal transplant. A controlled trial. Ann Intern Med (1991) 2.42

IgA antibody-producing cells in peripheral blood after antigen ingestion: evidence for a common mucosal immune system in humans. Proc Natl Acad Sci U S A (1987) 2.37

Regulated progression of a cultured pre-B-cell line to the B-cell stage. Nature (1985) 2.32

Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase. J Cereb Blood Flow Metab (1997) 2.31

Oromandibular reconstruction with the radial-forearm osteocutaneous flap: experience with 60 consecutive cases. Plast Reconstr Surg (1999) 2.30

Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells. Curr Biol (2001) 2.21

Long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency with the G1528C mutation: clinical presentation of thirteen patients. J Pediatr (1997) 2.12

Negative and positive health effects of caring for a disabled spouse: longitudinal findings from the caregiver health effects study. Psychol Aging (2000) 2.09

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo. Nat Med (1997) 2.07

Multicentre survey of radiologically inserted gastrostomy feeding tube (RIG) in the UK. Clin Radiol (2012) 2.04

Dams, development, and health: a missed opportunity. Lancet (2001) 2.04

VHDJH formation and DJH replacement during pre-B differentiation: non-random usage of gene segments. EMBO J (1986) 1.99

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin. Nat Med (1999) 1.98

Creatinine in urine as an index of urinary excretion rate. Health Phys (1966) 1.97

Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol (2000) 1.97

Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. Proc Natl Acad Sci U S A (1999) 1.88

Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat Res (2001) 1.85

Cancer incidence and risk estimation among medical x-ray workers in China, 1950-1995. Health Phys (2002) 1.85

Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers. J Biol Chem (1998) 1.79

Expression of the subtype 2 angiotensin (AT2) receptor protein in rat kidney. Hypertension (1997) 1.77

New approaches to understanding p53 gene tumor mutation spectra. Mutat Res (1999) 1.75

Expression and function of PPARgamma in rat and human vascular smooth muscle cells. Circulation (2000) 1.73

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes. Proc Natl Acad Sci U S A (1999) 1.71

Dopaminergic drug effects on physiological connectivity in a human cortico-striato-thalamic system. Brain (2003) 1.70

Osteoblasts are target cells for transformation in c-fos transgenic mice. J Cell Biol (1993) 1.70

Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathies. J Clin Invest (1986) 1.70

Questionnaires to assess urinary and anal incontinence: review and recommendations. J Urol (2007) 1.67

Involvement in caregiving and adjustment to death of a spouse: findings from the caregiver health effects study. JAMA (2001) 1.67

Treatment of late-onset asthma with fluconazole. J Allergy Clin Immunol (1999) 1.67

The human IgA system: a reassessment. Clin Immunol Immunopathol (1986) 1.64

Raised plasma soluble P-selectin in peripheral arterial occlusive disease enhances leukocyte adhesion. Circ Res (2005) 1.64

Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy. Contrib Nephrol (1993) 1.64

Immune responses to human immunodeficiency virus (HIV) type 1 induced by canarypox expressing HIV-1MN gp120, HIV-1SF2 recombinant gp120, or both vaccines in seronegative adults. NIAID AIDS Vaccine Evaluation Group. J Infect Dis (1998) 1.64

Molecular and biochemical characterization of xrs mutants defective in Ku80. Mol Cell Biol (1997) 1.62

NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase. J Neurosci (2000) 1.61

The prevalence and spectrum of alpha and beta thalassaemia in Guangdong Province: implications for the future health burden and population screening. J Clin Pathol (2004) 1.59

The role of helix formation in the folding of a fully alpha-helical coiled coil. Proteins (1996) 1.58

Disadvantaged women and smoking. Can J Public Health (1996) 1.57

JunB is essential for mammalian placentation. EMBO J (1999) 1.57

Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool. Oncogene (2001) 1.57

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability. Nat Genet (1999) 1.56

Inactivation of the poly(ADP-ribose) polymerase gene affects oxygen radical and nitric oxide toxicity in islet cells. J Biol Chem (1995) 1.56

Retinoids inhibit proliferation of human coronary smooth muscle cells by modulating cell cycle regulators. Arterioscler Thromb Vasc Biol (2001) 1.54

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis. Nat Genet (1997) 1.52

Resurgence of vivax malaria in Henan Province, China. Bull World Health Organ (1998) 1.52

Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. Eur J Pharmacol (1996) 1.52

Differences in gene content between Salmonella enterica serovar Enteritidis isolates and comparison to closely related serovars Gallinarum and Dublin. J Bacteriol (2005) 1.50

Surgical patterns of venous drainage of the free forearm flap in head and neck reconstruction. Plast Reconstr Surg (1994) 1.49

Delayed complications after esophageal stent placement for treatment of malignant esophageal obstructions and esophagorespiratory fistulas. J Vasc Interv Radiol (2001) 1.48

Surveillance of the first 205 confirmed hospitalised cases of pandemic H1N1 influenza in Ireland, 28 April - 3 October 2009. Euro Surveill (2009) 1.46

High-throughput screen for detecting antimycobacterial agents. Antimicrob Agents Chemother (1995) 1.46

Peroxynitrite decomposition catalysts: therapeutics for peroxynitrite-mediated pathology. Proc Natl Acad Sci U S A (1998) 1.45

Co-existing biliary anomalies and anatomical variants in choledochal cyst. Br J Surg (1998) 1.45

Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro. Am J Pathol (2001) 1.42

Circulating tumor cells in immunohistochemical subtypes of metastatic breast cancer: lack of prediction in HER2-positive disease treated with targeted therapy. Ann Oncol (2011) 1.42

Organ donation after paracetamol overdose. BMJ (1993) 1.41

Acute fatty liver of pregnancy and long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency. Hepatology (1994) 1.41

Differential scanning calorimetry study of mixed-chain phosphatidylcholines with a common molecular weight identical with diheptadecanoylphosphatidylcholine. Biochemistry (1990) 1.41

DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours. Oncogene (2007) 1.40

Clinical validity of a self-test fructosamine in outpatient diabetic management. Diabetes Technol Ther (1999) 1.38

Microsurgical tongue revascularization following oromandibular cancer resection. Plast Reconstr Surg (2001) 1.38

Failure of poly(ADP-ribose) polymerase cleavage by caspases leads to induction of necrosis and enhanced apoptosis. Mol Cell Biol (1999) 1.35

Role of the angiotensin type 2 receptor in the regulation of blood pressure and renal function. Hypertension (2000) 1.34

Placental vascularisation requires the AP-1 component fra1. Development (2000) 1.34

Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. J Invest Dermatol (1995) 1.31

Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20. Nucleic Acids Res (1998) 1.30

Case-control study of the health of those looked after by local authorities. Arch Dis Child (2001) 1.29

Eradication of schistosomiasis in Guangxi, China. Part 1: Setting, strategies, operations, and outcomes, 1953-92. Bull World Health Organ (1998) 1.28

Poly(ADP-ribose) polymerase: a guardian angel protecting the genome and suppressing tumorigenesis. Biochim Biophys Acta (2001) 1.27

Contribution of visceral fat mass to the insulin resistance of aging. Metabolism (1995) 1.25

Microdetermination of rabbit immunoglobulin allotypes by ELISA using specific antibodies conjugated with peroxidase or with biotin. J Immunol Methods (1982) 1.23

Ultraviolet irradiation activates PI 3-kinase/AKT survival pathway via EGF receptors in human skin in vivo. Int J Oncol (2001) 1.23

Smoking among disadvantaged women: causes and cessation. Can J Nurs Res (1996) 1.22

The epidemiology of human trichinellosis in China during 2004-2009. Acta Trop (2011) 1.22

Surveillance of cirrhosis for hepatocellular carcinoma: systematic review and economic analysis. Health Technol Assess (2007) 1.21

DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression. Mol Cell Biol (2001) 1.20

Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase. Proc Natl Acad Sci U S A (2000) 1.20

A DNA double-strand break defective fibroblast cell line (180BR) derived from a radiosensitive patient represents a new mutant phenotype. Cancer Res (1997) 1.19

Ultrastructure of Treponema pallidum Nichols following lysis by physical and chemical methods. I. Envelope, wall, membrane and fibrils. Arch Mikrobiol (1971) 1.18

Keratin 15 expression in stratified epithelia: downregulation in activated keratinocytes. J Invest Dermatol (1999) 1.16

Eradication of schistosomiasis in Guangxi, China. Part 2: Political economy, management strategy and costs, 1953-92. Bull World Health Organ (1998) 1.16

The complex CD44 transcriptional unit; alternative splicing of three internal exons generates the epithelial form of CD44. Biochem Biophys Res Commun (1992) 1.16

Oestrogens for urinary incontinence in women. Cochrane Database Syst Rev (2003) 1.16