Published in Am J Hum Genet on January 06, 2006
Telomere shortening in familial and sporadic pulmonary fibrosis. Am J Respir Crit Care Med (2008) 5.82
Telomere length is paternally inherited and is associated with parental lifespan. Proc Natl Acad Sci U S A (2007) 3.67
Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Aging Cell (2008) 3.24
Common variants near TERC are associated with mean telomere length. Nat Genet (2010) 2.98
Telomere length and mortality: a study of leukocytes in elderly Danish twins. Am J Epidemiol (2008) 2.85
Telomeres shorten at equivalent rates in somatic tissues of adults. Nat Commun (2013) 2.56
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A (2010) 2.47
Cohort Profile: TwinsUK and healthy ageing twin study. Int J Epidemiol (2012) 2.37
Telomere length in prospective and retrospective cancer case-control studies. Cancer Res (2010) 2.30
Associations between diet, lifestyle factors, and telomere length in women. Am J Clin Nutr (2010) 2.23
Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. Circulation (2008) 2.22
Telomere length in epidemiology: a biomarker of aging, age-related disease, both, or neither? Epidemiol Rev (2013) 2.05
Evolution in health and medicine Sackler colloquium: Genetic variation in human telomerase is associated with telomere length in Ashkenazi centenarians. Proc Natl Acad Sci U S A (2009) 1.96
Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study. Diabetes (2013) 1.91
A genome-wide association study identifies a locus on chromosome 14q21 as a predictor of leukocyte telomere length and as a marker of susceptibility for bladder cancer. Cancer Prev Res (Phila) (2011) 1.86
Race/ethnicity and telomere length in the Multi-Ethnic Study of Atherosclerosis. Aging Cell (2009) 1.85
The genetics and clinical manifestations of telomere biology disorders. Genet Med (2010) 1.83
Offspring's leukocyte telomere length, paternal age, and telomere elongation in sperm. PLoS Genet (2008) 1.80
Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur J Hum Genet (2013) 1.72
Synchrony of telomere length among hematopoietic cells. Exp Hematol (2010) 1.63
The role of telomere biology in bone marrow failure and other disorders. Mech Ageing Dev (2007) 1.56
The association of telomere length and genetic variation in telomere biology genes. Hum Mutat (2010) 1.53
A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk. Hum Mol Genet (2013) 1.52
Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control. Am J Hum Genet (2009) 1.51
A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length. J Med Genet (2009) 1.51
Telomere length and cognitive function in community-dwelling elders: findings from the Health ABC Study. Neurobiol Aging (2009) 1.46
Genetics of leukocyte telomere length and its role in atherosclerosis. Mutat Res (2011) 1.44
Inverse association between adiposity and telomere length: The Fels Longitudinal Study. Am J Hum Biol (2010) 1.37
Leukocyte telomere length is associated with cognitive performance in healthy women. Neurobiol Aging (2008) 1.36
Dietary patterns, food groups, and telomere length in the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Clin Nutr (2008) 1.35
Large-scale parent-child comparison confirms a strong paternal influence on telomere length. Eur J Hum Genet (2009) 1.33
Multiple genetic variants in telomere pathway genes and breast cancer risk. Cancer Epidemiol Biomarkers Prev (2010) 1.23
Early life stress and telomere length: investigating the connection and possible mechanisms: a critical survey of the evidence base, research methodology and basic biology. Bioessays (2012) 1.23
Genetic variation in TERT and TERC and human leukocyte telomere length and longevity: a cross-sectional and longitudinal analysis. Aging Cell (2011) 1.20
Greater endogenous estrogen exposure is associated with longer telomeres in postmenopausal women at risk for cognitive decline. Brain Res (2010) 1.16
Genome-wide association study of relative telomere length. PLoS One (2011) 1.16
Telomere length is inherited with resetting of the telomere set-point. Proc Natl Acad Sci U S A (2010) 1.15
Comparison between southern blots and qPCR analysis of leukocyte telomere length in the health ABC study. J Gerontol A Biol Sci Med Sci (2013) 1.15
Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33. Hum Mol Genet (2014) 1.09
Telomere length and the risk of cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations. PLoS One (2013) 1.07
No correlation between childhood maltreatment and telomere length. Biol Psychiatry (2010) 1.07
The association of telomere length with paternal history of premature myocardial infarction in the European Atherosclerosis Research Study II. J Mol Med (Berl) (2008) 1.06
Paternal age at birth is associated with offspring leukocyte telomere length in the nurses' health study. Hum Reprod (2012) 1.03
Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity. Biogerontology (2011) 1.03
Aging, telomeres and heart failure. Heart Fail Rev (2010) 1.02
The relationship between DXA-based and anthropometric measures of visceral fat and morbidity in women. BMC Cardiovasc Disord (2013) 1.01
Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer risk. Cancer Epidemiol Biomarkers Prev (2012) 1.00
Reduction of leucocyte telomere length in radiographic hand osteoarthritis: a population-based study. Ann Rheum Dis (2006) 1.00
Common variants near TERC are associated with leukocyte telomere length in the Chinese Han population. Eur J Hum Genet (2011) 0.95
Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration. Ann Rheum Dis (2006) 0.94
Genome wide association and linkage analyses identified three loci-4q25, 17q23.2, and 10q11.21-associated with variation in leukocyte telomere length: the Long Life Family Study. Front Genet (2014) 0.93
Telomeres, atherosclerosis, and human longevity: a causal hypothesis. Epidemiology (2015) 0.93
Diet-related telomere shortening and chromosome stability. Mutagenesis (2011) 0.92
Effects of brood size manipulation and common origin on phenotype and telomere length in nestling collared flycatchers. BMC Ecol (2012) 0.92
Functional haplotypes of the hTERT gene, leukocyte telomere length shortening, and the risk of peripheral arterial disease. PLoS One (2012) 0.91
Associations of cadmium and lead exposure with leukocyte telomere length: findings from National Health and Nutrition Examination Survey, 1999-2002. Am J Epidemiol (2014) 0.91
Association of TERC and OBFC1 haplotypes with mean leukocyte telomere length and risk for coronary heart disease. PLoS One (2013) 0.90
Genetic polymorphisms in telomere pathway genes, telomere length, and breast cancer survival. Breast Cancer Res Treat (2012) 0.90
QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study. Aging (Albany NY) (2013) 0.89
Maternal telomere length inheritance in the king penguin. Heredity (Edinb) (2014) 0.89
Cerebellar telomere length and psychiatric disorders. Behav Genet (2010) 0.88
The heritability of leucocyte telomere length dynamics. J Med Genet (2015) 0.87
Telomere length and common disease: study design and analytical challenges. Hum Genet (2015) 0.87
Sex difference in leukocyte telomere length is ablated in opposite-sex co-twins. Int J Epidemiol (2014) 0.84
A genome-wide association study identifies a locus on TERT for mean telomere length in Han Chinese. PLoS One (2014) 0.84
Genetic architecture of natural variation of telomere length in Arabidopsis thaliana. Genetics (2014) 0.82
Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme. Aging Cell (2011) 0.82
Heritability of telomere length in a study of long-lived families. Neurobiol Aging (2015) 0.82
Mediterranean diet and leukocyte telomere length in a multi-ethnic elderly population. Age (Dordr) (2015) 0.82
Sequence variation in telomerase reverse transcriptase (TERT) as a determinant of risk of cardiovascular disease: the Atherosclerosis Risk in Communities (ARIC) study. BMC Med Genet (2015) 0.81
Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort. Circ Cardiovasc Genet (2014) 0.81
Genetic variation in telomere maintenance genes, telomere length and breast cancer risk. PLoS One (2012) 0.81
Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases. F1000Res (2016) 0.81
Association between genetic variants in DNA and histone methylation and telomere length. PLoS One (2012) 0.80
QTL Mapping and Candidate Gene Analysis of Telomere Length Control Factors in Maize (Zea mays L.). G3 (Bethesda) (2011) 0.80
Constitutional and acquired autosomal aneuploidy. Clin Lab Med (2011) 0.77
Mother-offspring and nest-mate resemblance but no heritability in early-life telomere length in white-throated dippers. Proc Biol Sci (2015) 0.77
A test of biological and behavioral explanations for gender differences in telomere length: the multi-ethnic study of atherosclerosis. Biodemography Soc Biol (2014) 0.77
Does telomere length predict decline in physical functioning in older twin sisters during an 11-year follow-up? Age (Dordr) (2016) 0.76
Genetic variation in telomere maintenance genes in relation to ovarian cancer survival. Int J Mol Epidemiol Genet (2012) 0.76
Assessment of telomere length, phenotype, and DNA content. Curr Protoc Cytom (2004) 0.76
The Telomeric Complex and Metabolic Disease. Genes (Basel) (2017) 0.76
Discrimination and Telomere Length Among Older Adults in the United States. Public Health Rep (2017) 0.75
Estimating Telomere Length Heritability in an Unrelated Sample of Adults: Is Heritability of Telomere Length Modified by Life Course Socioeconomic Status? Biodemography Soc Biol (2016) 0.75
A biobehavioral perspective on telomere length and the exposome. Biol Res Nurs (2014) 0.75
The known genetic loci for telomere length may be involved in the modification of telomeres length after birth. Sci Rep (2016) 0.75
Relative Telomere Repeat Mass in Buccal and Leukocyte-Derived DNA. PLoS One (2017) 0.75
Dietary patterns, food groups and telomere length: a systematic review of current studies. Eur J Clin Nutr (2016) 0.75
Telomerase activity and the risk of lung cancer. J Korean Med Sci (2012) 0.75
Joint Assessment of Donor and Recipient hTERT Gene Polymorphism Provides Additional Information for Early Kidney Transplantation Outcomes. Med Sci Monit (2017) 0.75
Early life infection, but not breastfeeding, predicts adult blood telomere lengths in the Philippines. Am J Hum Biol (2017) 0.75
Assessment of Telomere Length, Phenotype, and DNA Content. Curr Protoc Cytom (2017) 0.75
Merlin--rapid analysis of dense genetic maps using sparse gene flow trees. Nat Genet (2001) 53.16
A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature (1996) 27.61
Telomeres shorten during ageing of human fibroblasts. Nature (1990) 23.97
A general test of association for quantitative traits in nuclear families. Am J Hum Genet (2000) 22.45
Extension of life-span by introduction of telomerase into normal human cells. Science (1998) 20.48
Telomere measurement by quantitative PCR. Nucleic Acids Res (2002) 18.69
Obesity, cigarette smoking, and telomere length in women. Lancet (2005) 8.59
Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet (2001) 7.53
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. N Engl J Med (2005) 7.09
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White cell telomere length and risk of premature myocardial infarction. Arterioscler Thromb Vasc Biol (2003) 5.04
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr Biol (1998) 4.59
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The rate of telomere sequence loss in human leukocytes varies with age. Proc Natl Acad Sci U S A (1998) 4.17
Telomere length as an indicator of biological aging: the gender effect and relation with pulse pressure and pulse wave velocity. Hypertension (2001) 4.07
Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data. Am J Hum Genet (2000) 3.69
Telomere length and possible link to X chromosome. Lancet (2004) 3.36
Mapping of a major locus that determines telomere length in humans. Am J Hum Genet (2004) 3.33
Telomere length inversely correlates with pulse pressure and is highly familial. Hypertension (2000) 3.32
Rise in insulin resistance is associated with escalated telomere attrition. Circulation (2005) 3.27
Telomere length in the newborn. Pediatr Res (2002) 3.26
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Telomere lengths are characteristic in each human individual. Exp Gerontol (2002) 2.13
Dyskeratosis congenita: telomerase, telomeres and anticipation. Curr Opin Genet Dev (2005) 1.50
Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis. Atherosclerosis (2000) 1.37
Human ageing and telomeres. Ciba Found Symp (1997) 1.25
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Telomerase therapeutics for degenerative diseases. Curr Mol Med (2005) 1.07
Gamma regression improves Haseman-Elston and variance components linkage analysis for sib-pairs. Genet Epidemiol (2004) 0.99
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Epigenetic differences arise during the lifetime of monozygotic twins. Proc Natl Acad Sci U S A (2005) 15.46
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Genome-wide association study identifies eight loci associated with blood pressure. Nat Genet (2009) 12.44
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet (2008) 12.32
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
Repeatability of published microarray gene expression analyses. Nat Genet (2008) 8.24
Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia. Am J Hum Genet (2008) 7.33
Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet (2012) 6.97
Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study. Lancet Neurol (2008) 6.76
The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med (2004) 6.55
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior. Nat Genet (2010) 6.49
Heritability of adult body height: a comparative study of twin cohorts in eight countries. Twin Res (2003) 6.43
A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet (2009) 6.31
Leukocyte telomere length and cardiovascular disease in the cardiovascular health study. Am J Epidemiol (2006) 5.28
Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains. Genome Res (2010) 5.08
A genome-wide perspective of genetic variation in human metabolism. Nat Genet (2009) 5.00
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet (2009) 4.97
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15. Nat Genet (2007) 4.61
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Gene transfer in humans using a conditionally replicating lentiviral vector. Proc Natl Acad Sci U S A (2006) 4.23
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population. PLoS Genet (2012) 4.05
Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet (2013) 3.87
The association between physical activity in leisure time and leukocyte telomere length. Arch Intern Med (2008) 3.68
Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. Lancet (2012) 3.48
Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci. PLoS Genet (2007) 3.47
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Telomere length and possible link to X chromosome. Lancet (2004) 3.36
Rise in insulin resistance is associated with escalated telomere attrition. Circulation (2005) 3.27
Telomere length in the newborn. Pediatr Res (2002) 3.26
Leukocyte telomeres are longer in African Americans than in whites: the National Heart, Lung, and Blood Institute Family Heart Study and the Bogalusa Heart Study. Aging Cell (2008) 3.24
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
New gene functions in megakaryopoiesis and platelet formation. Nature (2011) 3.14
Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults. Proc Natl Acad Sci U S A (2007) 3.10
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations. Nat Genet (2012) 3.04
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Geographical structure and differential natural selection among North European populations. Genome Res (2009) 3.03
Common variants near TERC are associated with mean telomere length. Nat Genet (2010) 2.98
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Impartial comparative analysis of measurement of leukocyte telomere length/DNA content by Southern blots and qPCR. Nucleic Acids Res (2011) 2.92
Measurement of telomere length by the Southern blot analysis of terminal restriction fragment lengths. Nat Protoc (2010) 2.88
Leukocyte telomere dynamics: longitudinal findings among young adults in the Bogalusa Heart Study. Am J Epidemiol (2008) 2.86
Telomere length and mortality: a study of leukocytes in elderly Danish twins. Am J Epidemiol (2008) 2.85
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med (2009) 2.80
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet (2009) 2.58
Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet (2010) 2.57
Telomeres shorten at equivalent rates in somatic tissues of adults. Nat Commun (2013) 2.56
Genome-wide association identifies OBFC1 as a locus involved in human leukocyte telomere biology. Proc Natl Acad Sci U S A (2010) 2.47
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand. Arthritis Rheum (2009) 2.47
The relationship of bone density and fracture to incident and progressive radiographic osteoarthritis of the knee: the Chingford Study. Arthritis Rheum (2002) 2.42
Short telomeres are associated with increased carotid atherosclerosis in hypertensive subjects. Hypertension (2004) 2.41
A twin approach to unraveling epigenetics. Trends Genet (2011) 2.38
Cohort Profile: TwinsUK and healthy ageing twin study. Int J Epidemiol (2012) 2.37
Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia. Nat Genet (2013) 2.36
Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. PLoS Genet (2011) 2.34
Activation markers of coagulation and fibrinolysis in twins: heritability of the prethrombotic state. Lancet (2002) 2.26
Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. Circulation (2008) 2.22
Leukocyte telomere length and mortality in the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci (2011) 2.19