Published in Appl Environ Microbiol on February 01, 2002
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A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism. Nature (2008) 2.22
Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range. Opt Express (2009) 2.03
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Gender-selective patterns of aggressive behavior in Drosophila melanogaster. Proc Natl Acad Sci U S A (2004) 1.99
Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding. J Am Chem Soc (2006) 1.96
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Crystal structures of transcription factor NusG in light of its nucleic acid- and protein-binding activities. EMBO J (2002) 1.79
Yeast MPH1 gene functions in an error-free DNA damage bypass pathway that requires genes from Homologous recombination, but not from postreplicative repair. Genetics (2004) 1.76
Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. EMBO J (2004) 1.75
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K-space linear Fourier domain mode locked laser and applications for optical coherence tomography. Opt Express (2008) 1.62
The crystal structure of dipeptidyl peptidase IV (CD26) reveals its functional regulation and enzymatic mechanism. Proc Natl Acad Sci U S A (2003) 1.62
Improved spectral optical coherence tomography using optical frequency comb. Opt Express (2008) 1.58
Catalysis at a dinuclear [CuSMo(==O)OH] cluster in a CO dehydrogenase resolved at 1.1-A resolution. Proc Natl Acad Sci U S A (2002) 1.57
New prognostic score based on treatment outcome of patients with relapsed Hodgkin's lymphoma registered in the database of the German Hodgkin's lymphoma study group. J Clin Oncol (2002) 1.53
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A functional Ni-Ni-[4Fe-4S] cluster in the monomeric acetyl-CoA synthase from Carboxydothermus hydrogenoformans. Proc Natl Acad Sci U S A (2003) 1.52
Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective. Brain Res Rev (2007) 1.50
Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins. Proc Natl Acad Sci U S A (2008) 1.48
Structure of the metal-independent restriction enzyme BfiI reveals fusion of a specific DNA-binding domain with a nonspecific nuclease. Proc Natl Acad Sci U S A (2005) 1.47
Gene transfer and genome plasticity in Thermotoga maritima, a model hyperthermophilic species. J Bacteriol (2005) 1.45
Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development. J Biol Chem (2003) 1.40
Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure (2003) 1.39
The 1.9-A crystal structure of the noncollagenous (NC1) domain of human placenta collagen IV shows stabilization via a novel type of covalent Met-Lys cross-link. Proc Natl Acad Sci U S A (2002) 1.38
Multi-MHz retinal OCT. Biomed Opt Express (2013) 1.36
Mechanism of the six-electron reduction of nitrite to ammonia by cytochrome c nitrite reductase. J Am Chem Soc (2002) 1.36
Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach. Biochim Biophys Acta (2004) 1.36
Expansion of the genetic code enables design of a novel "gold" class of green fluorescent proteins. J Mol Biol (2003) 1.34
Structure of the streptococcal endopeptidase IdeS, a cysteine proteinase with strict specificity for IgG. Proc Natl Acad Sci U S A (2004) 1.32
Investigations on the maturation and regulation of archaebacterial proteasomes. J Mol Biol (2003) 1.32
High-resolution positional tracking for long-term analysis of Drosophila sleep and locomotion using the "tracker" program. PLoS One (2012) 1.30
Structure of the stapled p53 peptide bound to Mdm2. J Am Chem Soc (2011) 1.30
HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues. Nat Struct Mol Biol (2010) 1.30
Substrate access and processing by the 20S proteasome core particle. Int J Biochem Cell Biol (2003) 1.29
Protein quality control in the bacterial periplasm. Annu Rev Microbiol (2011) 1.29
Catalytic domain structures of MT-SP1/matriptase, a matrix-degrading transmembrane serine proteinase. J Biol Chem (2001) 1.27
Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein. Proc Natl Acad Sci U S A (2003) 1.27
Ultrahigh-speed non-invasive widefield angiography. J Biomed Opt (2012) 1.25
Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations. J Mol Biol (2005) 1.25
Crystal structure of the Bse634I restriction endonuclease: comparison of two enzymes recognizing the same DNA sequence. Nucleic Acids Res (2002) 1.24
Crystal structure of 12-oxophytodienoate reductase 3 from tomato: self-inhibition by dimerization. Proc Natl Acad Sci U S A (2006) 1.24
New isolates and physiological properties of the Aquificales and description of Thermocrinis albus sp. nov. Extremophiles (2002) 1.24
Gene sequence and the 1.8 A crystal structure of the tungsten-containing formate dehydrogenase from Desulfovibrio gigas. Structure (2002) 1.23
Crystal structure of the dinuclear zinc aminopeptidase PepV from Lactobacillus delbrueckii unravels its preference for dipeptides. Structure (2002) 1.20
Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. Eur J Biochem (2004) 1.20
Flavin mononucleotide-based fluorescent reporter proteins outperform green fluorescent protein-like proteins as quantitative in vivo real-time reporters. Appl Environ Microbiol (2010) 1.19
The unique structure of archaeal 'hami', highly complex cell appendages with nano-grappling hooks. Mol Microbiol (2005) 1.19
Crystal structure of the human CCA-adding enzyme: insights into template-independent polymerization. J Mol Biol (2003) 1.19
High speed engine gas thermometry by Fourier-domain mode-locked laser absorption spectroscopy. Opt Express (2007) 1.19
Structural basis of the adaptive molecular recognition by MMP9. J Mol Biol (2002) 1.18
Halorhabdus tiamatea sp. nov., a non-pigmented, extremely halophilic archaeon from a deep-sea, hypersaline anoxic basin of the Red Sea, and emended description of the genus Halorhabdus. Int J Syst Evol Microbiol (2008) 1.18
Intravascular optical coherence tomography imaging at 3200 frames per second. Opt Lett (2013) 1.17
Kinetic stabilization of Bacillus licheniformis alpha-amylase through introduction of hydrophobic residues at the surface. J Biol Chem (2003) 1.17
Salinisphaera shabanensis gen. nov., sp. nov., a novel, moderately halophilic bacterium from the brine-seawater interface of the Shaban Deep, Red Sea. Extremophiles (2002) 1.16
Application of NMR in structural proteomics: screening for proteins amenable to structural analysis. Structure (2002) 1.15
Crystal structures of MMP-9 complexes with five inhibitors: contribution of the flexible Arg424 side-chain to selectivity. J Mol Biol (2007) 1.13
Crystal structure of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Bacillus subtilis. J Mol Biol (2003) 1.13
Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli. Res Microbiol (2009) 1.12
Molecular structure of the rod domain of dictyostelium filamin. J Mol Biol (2004) 1.12
Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3. Proc Natl Acad Sci U S A (2009) 1.11
Structural basis for the inhibition of insulin-like growth factors by insulin-like growth factor-binding proteins. Proc Natl Acad Sci U S A (2006) 1.11
A new lineage of halophilic, wall-less, contractile bacteria from a brine-filled deep of the Red Sea. J Bacteriol (2008) 1.10
Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein. Proc Natl Acad Sci U S A (2009) 1.10
Determinants of enzymatic specificity in the Cys-Met-metabolism PLP-dependent enzymes family: crystal structure of cystathionine gamma-lyase from yeast and intrafamiliar structure comparison. Biol Chem (2003) 1.10
In situ structural and microangiographic assessment of human skin lesions with high-speed OCT. Biomed Opt Express (2012) 1.10
Active site geometry and substrate recognition of the molybdenum hydroxylase quinoline 2-oxidoreductase. Structure (2004) 1.09
Purification, crystallization, and X-ray analysis of the yeast 20S proteasome. Methods Enzymol (2005) 1.08
Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY). Proc Natl Acad Sci U S A (2002) 1.08
Cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774. The relevance of the two calcium sites in the structure of the catalytic subunit (NrfA). J Biol Chem (2003) 1.08
Crystal structure of fervidolysin from Fervidobacterium pennivorans, a keratinolytic enzyme related to subtilisin. J Mol Biol (2004) 1.07
Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition. Proc Natl Acad Sci U S A (2009) 1.07
Prokaryotic phylogenetic diversity and corresponding geochemical data of the brine-seawater interface of the Shaban Deep, Red Sea. Environ Microbiol (2002) 1.07
Determinants of structural and functional plasticity of a widely conserved protease chaperone complex. Nat Struct Mol Biol (2010) 1.07
Biosynthesis of pteridines. Reaction mechanism of GTP cyclohydrolase I. J Mol Biol (2003) 1.06
A variant of the hyperthermophile Archaeoglobus fulgidus adapted to grow at high salinity. FEMS Microbiol Lett (2003) 1.06
Crystal structures of active SRC kinase domain complexes. J Mol Biol (2005) 1.05
1.2 A crystal structure of the serine carboxyl proteinase pro-kumamolisin; structure of an intact pro-subtilase. Structure (2004) 1.05
Crystal structure of the carboxyltransferase subunit of the bacterial sodium ion pump glutaconyl-coenzyme A decarboxylase. EMBO J (2003) 1.04
The endoproteinase furin contains two essential Ca2+ ions stabilizing its N-terminus and the unique S1 specificity pocket. Acta Crystallogr D Biol Crystallogr (2005) 1.03
The 1.1 A resolution crystal structure of the p130cas SH3 domain and ramifications for ligand selectivity. J Mol Biol (2005) 1.02
Studies on the reaction mechanism of riboflavin synthase: X-ray crystal structure of a complex with 6-carboxyethyl-7-oxo-8-ribityllumazine. Structure (2002) 1.01
Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome. Chem Biol (2002) 1.01
The persisting challenge of selective and specific proteasome inhibition. J Pept Sci (2009) 1.01
Real time en face Fourier-domain optical coherence tomography with direct hardware frequency demodulation. Opt Lett (2008) 1.01
Ecology and microbial structures of archaeal/bacterial strings-of-pearls communities and archaeal relatives thriving in cold sulfidic springs. FEMS Microbiol Ecol (2004) 1.00
Structure-based optimization of novel azepane derivatives as PKB inhibitors. J Med Chem (2004) 1.00
In situ growth of the novel SM1 euryarchaeon from a string-of-pearls-like microbial community in its cold biotope, its physical separation and insights into its structure and physiology. Arch Microbiol (2003) 1.00