Published in EMBO J on January 01, 1983
pEMBL: a new family of single stranded plasmids. Nucleic Acids Res (1983) 19.19
The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species. Nucleic Acids Res (1984) 2.57
Structure and cell-specific expression of a cloned human retinol binding protein gene: the 5'-flanking region contains hepatoma specific transcriptional signals. EMBO J (1985) 2.05
Molecular cloning of human haptoglobin cDNA: evidence for a single mRNA coding for alpha 2 and beta chains. EMBO J (1983) 1.94
The human alpha 1-antitrypsin gene is transcribed from two different promoters in macrophages and hepatocytes. EMBO J (1987) 1.85
High-level production of biologically active human alpha 1-antitrypsin in Escherichia coli. Proc Natl Acad Sci U S A (1984) 1.65
Cloning and sequencing of a full length cDNA coding for a human apoferritin H chain: evidence for a multigene family. EMBO J (1984) 1.42
Cloning and sequencing of a full length cDNA coding for human retinol-binding protein. Nucleic Acids Res (1983) 1.36
Complete amino acid sequence for human aldolase B derived from cDNA and genomic clones. Proc Natl Acad Sci U S A (1984) 1.30
Sequence of human haptoglobin cDNA: evidence that the alpha and beta subunits are coded by the same mRNA. Nucleic Acids Res (1983) 1.29
Isolation and nucleotide sequence of a full-length cDNA coding for aldolase B from human liver. Nucleic Acids Res (1984) 1.28
The predicted secondary structures of class I fructose-bisphosphate aldolases. Biochem J (1988) 0.94
The complete amino acid sequence of human skeletal-muscle fructose-bisphosphate aldolase. Biochem J (1988) 0.80
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc Natl Acad Sci U S A (1972) 83.88
Sequence and organization of the human mitochondrial genome. Nature (1981) 57.39
An efficient mRNA-dependent translation system from reticulocyte lysates. Eur J Biochem (1976) 46.42
Sequence data handling by computer. Nucleic Acids Res (1977) 45.33
Further procedures for sequence analysis by computer. Nucleic Acids Res (1978) 18.94
The making of strand-specific M13 probes. Gene (1982) 14.60
Methylation of single-stranded DNA in vitro introduces new restriction endonuclease cleavage sites. Nature (1978) 8.54
Human metallothionein genes--primary structure of the metallothionein-II gene and a related processed gene. Nature (1982) 7.05
The phenomenon of the acute phase response. Ann N Y Acad Sci (1982) 6.14
Structure and variation of human alpha 1-antitrypsin. Nature (1982) 4.13
Transcriptional control of the murine albumin/alpha-fetoprotein locus during development. Proc Natl Acad Sci U S A (1982) 3.37
The sequence of human serum albumin cDNA and its expression in E. coli. Nucleic Acids Res (1981) 2.97
Cloning of nematode tRNA genes and their expression in the frog oocyte. Nucleic Acids Res (1978) 2.91
Structures of the genes for the beta and epsilon subunits of spinach chloroplast ATPase indicate a dicistronic mRNA and an overlapping translation stop/start signal. Proc Natl Acad Sci U S A (1982) 2.86
Transcription of tRNA genes in vivo: single-stranded compared to double-stranded templates. Proc Natl Acad Sci U S A (1980) 2.73
Covalent structure of human haptoglobin: a serine protease homolog. Proc Natl Acad Sci U S A (1980) 2.21
Hormonal inducibility of rat alpha 2u globulin genes in transfected mouse cells. Nature (1981) 2.05
Cloning and sequence of cDNA coding for alpha 1-antitrypsin. Proc Natl Acad Sci U S A (1981) 1.91
mRNA in human cells contains sequences complementary to the Alu family of repeated DNA. Proc Natl Acad Sci U S A (1981) 1.32
Glucocorticoid regulation of the mouse metallothionein I gene is selectively lost following amplification of the gene. J Biol Chem (1982) 1.28
The primary structure of the human retinol-binding protein. FEBS Lett (1979) 1.16
Regulation of retinol-binding protein metabolism in cultured rat liver cell lines. Cell (1978) 1.01
Kinetics of induction of alpha 1-acid glycoprotein. Ann N Y Acad Sci (1982) 0.97
Nucleotide sequence of bacteriophage phi X174 DNA. Nature (1977) 95.69
pEMBL: a new family of single stranded plasmids. Nucleic Acids Res (1983) 19.19
Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors. Methods Enzymol (1983) 17.47
Oligonucleotide-directed mutagenesis: a simple method using two oligonucleotide primers and a single-stranded DNA template. DNA (1984) 14.55
The nucleotide sequence of bacteriophage phiX174. J Mol Biol (1978) 13.55
Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA. Nucleic Acids Res (1982) 13.52
A general method for defining restriction enzyme cleavage and recognition sites. Methods Enzymol (1980) 13.26
Sequence of the gene for iso-1-cytochrome c in Saccharomyces cerevisiae. Cell (1979) 10.86
Routine versus clinically driven laboratory monitoring of HIV antiretroviral therapy in Africa (DART): a randomised non-inferiority trial. Lancet (2009) 7.96
A fast and simple method for sequencing DNA cloned in the single-stranded bacteriophage M13. J Mol Biol (1979) 7.73
Mutagenesis at a specific position in a DNA sequence. J Biol Chem (1978) 7.56
Report of the Committee on the Genetic Constitution of Chromosomes 7, 8 and 9. Cytogenet Cell Genet (1985) 7.28
Neutrophilic-chronic myeloid leukemia: a distinct disease with a specific molecular marker (BCR/ABL with C3/A2 junction) Blood (1996) 6.36
The specific non-symmetrical sequence recognized by restriction endonuclease MboII. J Mol Biol (1980) 6.36
Deletion mapping of sequences essential for in vivo transcription of the iso-1-cytochrome c gene. Proc Natl Acad Sci U S A (1981) 6.26
Environmental lead and children's intelligence: a systematic review of the epidemiological evidence. BMJ (1994) 5.55
The sequence of the DNAs coding for the mating-type loci of Saccharomyces cerevisiae. Cell (1981) 5.23
A position effect in the control of transcription at yeast mating type loci. Nature (1981) 5.23
The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence. Cell (1984) 5.10
The alcohol use disorder and associated disabilities interview schedule (AUDADIS): reliability of alcohol and drug modules in a clinical sample. Drug Alcohol Depend (1997) 5.10
Four mating-type genes control sexual differentiation in the fission yeast. EMBO J (1988) 5.00
Site-specific mutagenesis using synthetic oligodeoxyribonucleotide primers: II. In vitro selection of mutant DNA. Gene (1979) 4.99
The DNA sequence and analysis of human chromosome 6. Nature (2003) 4.75
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing. Nature (2000) 4.68
Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron (1999) 4.68
A novel method for site-directed mutagenesis: its application to an eukaryotic tRNAPro gene promoter. EMBO J (1982) 4.67
IL-6DBP, a nuclear protein involved in interleukin-6 signal transduction, defines a new family of leucine zipper proteins related to C/EBP. Cell (1990) 4.58
HIV-1 protease inhibitors. A review for clinicians. JAMA (1997) 4.34
Work system design for patient safety: the SEIPS model. Qual Saf Health Care (2006) 4.21
How biomedical investigators use library books. Bull Med Libr Assoc (1966) 4.20
A general method to select for M13 clones carrying base pair substitution mutants constructed in vitro. Nucleic Acids Res (1983) 4.14
Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB. Diabetes (2001) 3.83
Report of the committee on the genetic constitution of chromosomes 9 and 10. Cytogenet Cell Genet (1989) 3.79
Sequence comparison of five polymerases (L proteins) of unsegmented negative-strand RNA viruses: theoretical assignment of functional domains. J Gen Virol (1990) 3.72
Isolation and sequence of the gene for iso-2-cytochrome c in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1980) 3.62
[Mutant tRNA His ineffective in repression and lacking two pseudouridine modifications]. Nat New Biol (1972) 3.57
The liver-specific transcription factor LF-B1 contains a highly diverged homeobox DNA binding domain. Cell (1989) 3.51
Undergraduate research. Genomics Education Partnership. Science (2008) 3.45
High-level, plasmid-borne resistance to gentamicin in Streptococcus faecalis subsp. zymogenes. Antimicrob Agents Chemother (1979) 3.42
Identification and isolation of the yeast cytochrome c gene. Cell (1978) 3.39
The mapping and sequence determination of the single site in phiX174am3 replicative form DNA cleaved by restriction endonuclease Pst I. FEBS Lett (1976) 3.31
Prostate Testing for Cancer and Treatment (ProtecT) feasibility study. Health Technol Assess (2003) 3.25
Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nat Genet (1999) 3.25
Mutations of the yeast SUP4 tRNATyr locus: transcription of the mutant genes in vitro. Cell (1980) 3.24
Two different liver-specific factors stimulate in vitro transcription from the human alpha 1-antitrypsin promoter. EMBO J (1988) 3.14
Molecular cloning and characterization of protective outer membrane protein P.69 from Bordetella pertussis. Proc Natl Acad Sci U S A (1989) 3.13
The base-pairing specificity of cellulose-pdT9. Nucleic Acids Res (1975) 3.11
The Epstein-Barr virus BMLF1 promoter contains an enhancer element that is responsive to the BZLF1 and BRLF1 transactivators. J Virol (1989) 3.11
In vitro mutation analysis of the mating-type locus in yeast. Cell (1981) 3.09
Order and intracellular location of the events involved in the maturation of a spliced tRNA. Nature (1980) 3.07
Site-specific mutagenesis using synthetic oligodeoxyribonucleotide primers: I. Optimum conditions and minimum ologodeoxyribonucleotide length. Gene (1979) 3.05
Cell-specific expression of a transfected human alpha 1-antitrypsin gene. Cell (1985) 2.99
Common and interchangeable elements in the promoters of genes transcribed by RNA polymerase iii. Cell (1983) 2.94
Loss of heterozygosity on chromosome 16p13.3 in hamartomas from tuberous sclerosis patients. Nat Genet (1994) 2.93
Physical interaction with Yes-associated protein enhances p73 transcriptional activity. J Biol Chem (2001) 2.93
Cloning of nematode tRNA genes and their expression in the frog oocyte. Nucleic Acids Res (1978) 2.91
Characterization of a short, cis-acting DNA sequence which conveys cell cycle stage-dependent transcription in Saccharomyces cerevisiae. Mol Cell Biol (1991) 2.91
Promoter of a eukaryotic tRNAPro gene is composed of three noncontiguous regions. Proc Natl Acad Sci U S A (1982) 2.91
Multisystem involvement in chronic liver disease. Studies on the incidence and pathogenesis. Am J Med (1973) 2.88
Mapping through somatic cell hybrids and cDNA probes of protein C to chromosome 2, factor X to chromosome 13, and alpha 1-acid glycoprotein to chromosome 9. Hum Genet (1986) 2.84
Nucleotide sequence of the yeast alcohol dehydrogenase II gene. J Biol Chem (1983) 2.82
Structure of the 3' hairpin termini of four rodent parvovirus genomes: nucleotide sequence homology at origins of DNA replication. Cell (1979) 2.78
Transcription of tRNA genes in vivo: single-stranded compared to double-stranded templates. Proc Natl Acad Sci U S A (1980) 2.73
In vitro mutagenesis. Annu Rev Genet (1985) 2.72
Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol Cell Biol (1988) 2.70
Cis- and trans-acting elements responsible for the cell-specific expression of the human alpha 1-antitrypsin gene. EMBO J (1987) 2.69
Hormone replacement therapy and breast cancer: what are the facts? Med J Aust (1995) 2.66
Redesigning enzyme structure by site-directed mutagenesis: tyrosyl tRNA synthetase and ATP binding. Nature (1982) 2.63
Transcription by RNA polymerase III. Curr Top Dev Biol (1983) 2.63
Primary sequence and immunological characterization of beta-subunit of high conductance Ca(2+)-activated K+ channel from smooth muscle. J Biol Chem (1994) 2.62
Frequent activation of N-myc genes by hepadnavirus insertion in woodchuck liver tumours. Nature (1990) 2.61
Purification of a NF1-like DNA-binding protein from rat liver and cloning of the corresponding cDNA. EMBO J (1988) 2.60
Treatment decision-making at the end of life: a survey of Australian doctors' attitudes towards patients' wishes and euthanasia. Med J Aust (1996) 2.59
Structure of the human alpha 1-acid glycoprotein gene: sequence homology with other human acute phase protein genes. Nucleic Acids Res (1985) 2.59
Oligonucleotide-directed mutagenesis: a simple method using two oligonucleotide primers and a single-stranded DNA template. Methods Enzymol (1987) 2.59
Conjugative R plasmids in Streptococcus agalactiae (group B). Plasmid (1979) 2.57
The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species. Nucleic Acids Res (1984) 2.57
Characterization of the genes coding for the Eco RV restriction and modification system of Escherichia coli. Nucleic Acids Res (1984) 2.52
Conjugative transfer of multiple-antibiotic resistance markers in beta-hemolytic group A, B, F, and G streptococci in the absence of extrachromosomal deoxyribonucleic acid. Plasmid (1981) 2.51
DNA sequences of two yeast promoter-up mutants. Nature (1983) 2.50
Regional gene assignment of human porphobilinogen deaminase and esterase A4 to chromosome 11q23 leads to 11qter. Proc Natl Acad Sci U S A (1981) 2.50
How white and African Americans view their health and social problems. Different experiences, different expectations. JAMA (1995) 2.48
Psychiatric Research Interview for Substance and Mental Disorders (PRISM): reliability for substance abusers. Am J Psychiatry (1996) 2.47
Nucleotide sequence of salmon testes and salmon liver cytoplasmic initiator tRNA. Cell (1975) 2.46
Cryptosporidiosis in hospital patients with gastroenteritis. Am J Trop Med Hyg (1983) 2.45
The role of emotionality and regulation in children's social functioning: a longitudinal study. Child Dev (1995) 2.43
The DNA sequence and biological annotation of human chromosome 1. Nature (2006) 2.42
Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff. Mol Cell Biol (2000) 2.41
Recombinant interleukin 6 regulates the transcriptional activation of a set of human acute phase genes. J Biol Chem (1988) 2.40