Published in Nat Struct Biol on August 01, 2002
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Desmosomal dysfunction due to mutations in desmoplakin causes arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ Res (2006) 2.95
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An epithelial tissue in Dictyostelium challenges the traditional origin of metazoan multicellularity. Bioessays (2012) 2.81
Working out the strength and flexibility of desmosomes. Nat Rev Mol Cell Biol (2004) 2.63
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High-resolution crystal structure of human protease-activated receptor 1. Nature (2012) 2.44
Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle. Nat Struct Biol (2002) 2.38
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Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature (2013) 2.14
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p120 catenin associates with kinesin and facilitates the transport of cadherin-catenin complexes to intercellular junctions. J Cell Biol (2003) 2.02
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Deconstructing the skin: cytoarchitectural determinants of epidermal morphogenesis. Nat Rev Mol Cell Biol (2011) 1.94
Plakins: a family of versatile cytolinker proteins. Trends Cell Biol (2002) 1.91
ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules. Mol Cell (2002) 1.88
Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling. PLoS One (2008) 1.86
Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling. J Biol Chem (2002) 1.84
Intermediate filament-membrane attachments function synergistically with actin-dependent contacts to regulate intercellular adhesive strength. J Cell Biol (2002) 1.83
AlphaE-catenin regulates actin dynamics independently of cadherin-mediated cell-cell adhesion. J Cell Biol (2010) 1.81
Regulation of desmosome assembly and adhesion. Semin Cell Dev Biol (2004) 1.74
Desmoglein 1-dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis. J Cell Biol (2009) 1.73
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Plakophilin 2: a critical scaffold for PKC alpha that regulates intercellular junction assembly. J Cell Biol (2008) 1.47
Desmoplakin regulates desmosome hyperadhesion. J Invest Dermatol (2011) 1.41
G4-forming sequences in the non-transcribed DNA strand pose blocks to T7 RNA polymerase and mammalian RNA polymerase II. J Biol Chem (2008) 1.40
Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells. J Biol Chem (2004) 1.37
Crystal structure of the S.cerevisiae exocyst component Exo70p. J Mol Biol (2005) 1.37
In vitro and in vivo reconstitution of the cadherin-catenin-actin complex from Caenorhabditis elegans. Proc Natl Acad Sci U S A (2010) 1.37
Defining desmosomal plakophilin-3 interactions. J Cell Biol (2003) 1.36
Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism. Nature (2007) 1.36
Desmoplakin assembly dynamics in four dimensions: multiple phases differentially regulated by intermediate filaments and actin. J Cell Biol (2005) 1.35
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Biochemical and structural analysis of alpha-catenin in cell-cell contacts. Biochem Soc Trans (2008) 1.32
Discriminating roles of desmosomal cadherins: beyond desmosomal adhesion. J Dermatol Sci (2006) 1.32
Plakoglobin suppresses keratinocyte motility through both cell-cell adhesion-dependent and -independent mechanisms. Proc Natl Acad Sci U S A (2005) 1.29
Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium. Mol Biol Cell (2007) 1.27
αE-catenin is an autoinhibited molecule that coactivates vinculin. Proc Natl Acad Sci U S A (2012) 1.25
Direct ubiquitination of beta-catenin by Siah-1 and regulation by the exchange factor TBL1. J Biol Chem (2010) 1.18
The differentiation-dependent desmosomal cadherin desmoglein 1 is a novel caspase-3 target that regulates apoptosis in keratinocytes. J Biol Chem (2005) 1.17
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Multiple modes of binding enhance the affinity of DC-SIGN for high mannose N-linked glycans found on viral glycoproteins. J Biol Chem (2006) 1.17
Coordinated expression of desmoglein 1 and desmocollin 1 regulates intercellular adhesion. Differentiation (2004) 1.17
Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor. J Biol Chem (2005) 1.15
Mechanism for recognition of an unusual mycobacterial glycolipid by the macrophage receptor mincle. J Biol Chem (2013) 1.15
The cytoplasmic face of cell contact sites. Curr Opin Struct Biol (2002) 1.14
Interaction of the bullous pemphigoid antigen 1 (BP230) and desmoplakin with intermediate filaments is mediated by distinct sequences within their COOH terminus. Mol Biol Cell (2003) 1.14
Desmosomes at a glance. J Cell Sci (2009) 1.14
Plakophilins: multifunctional scaffolds for adhesion and signaling. Curr Opin Cell Biol (2009) 1.13
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation. J Clin Invest (2013) 1.11
Structure of the armadillo repeat domain of plakophilin 1. J Mol Biol (2004) 1.10
Three-dimensional structure of the amino-terminal domain of syntaxin 6, a SNAP-25 C homolog. Proc Natl Acad Sci U S A (2002) 1.10
Scavenger receptor C-type lectin binds to the leukocyte cell surface glycan Lewis(x) by a novel mechanism. J Biol Chem (2007) 1.08
Plakoglobin regulates cell motility through Rho- and fibronectin-dependent Src signaling. J Cell Sci (2010) 1.08
EGFR and ADAMs cooperate to regulate shedding and endocytic trafficking of the desmosomal cadherin desmoglein 2. Mol Biol Cell (2008) 1.07
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Plakophilin 2 couples actomyosin remodeling to desmosomal plaque assembly via RhoA. Mol Biol Cell (2010) 1.04
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Intermediate filament assembly: dynamics to disease. Trends Cell Biol (2008) 1.01
The calcium ATPase SERCA2 regulates desmoplakin dynamics and intercellular adhesive strength through modulation of PKCα signaling. FASEB J (2010) 1.01
The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism. Cancer Prev Res (Phila) (2009) 1.00
Structure, function, and regulation of desmosomes. Prog Mol Biol Transl Sci (2013) 1.00
New insights into the molecular basis of desmoplakin- and desmin-related cardiomyopathies. J Cell Sci (2006) 0.99
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Desmosomal cadherins utilize distinct kinesins for assembly into desmosomes. J Cell Biol (2011) 0.98