Published in JAMA on October 21, 2002
Health Professionals Follow-up Study | NCT00005182
The Cycle Nation Project (Phase 2: Feasibility) | NCT04035941
Heart disease and stroke statistics--2012 update: a report from the American Heart Association. Circulation (2011) 31.98
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A review of the application of propensity score methods yielded increasing use, advantages in specific settings, but not substantially different estimates compared with conventional multivariable methods. J Clin Epidemiol (2005) 7.31
A systematic review of the evidence for Canada's Physical Activity Guidelines for Adults. Int J Behav Nutr Phys Act (2010) 4.05
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Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol (2004) 3.48
The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease. Nat Rev Immunol (2011) 2.77
The association between physical activity and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol (2008) 2.43
Physical activity and survival after prostate cancer diagnosis in the health professionals follow-up study. J Clin Oncol (2011) 2.42
Gotta catch'em all! Pokémon GO and physical activity among young adults: difference in differences study. BMJ (2016) 2.17
Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease. Am J Gastroenterol (2011) 2.15
Effect of exercise intensity on abdominal fat loss during calorie restriction in overweight and obese postmenopausal women: a randomized, controlled trial. Am J Clin Nutr (2009) 1.77
Association between fear of crime and mental health and physical functioning. Am J Public Health (2007) 1.74
Can exercise teach us how to treat heart disease? Circulation (2012) 1.70
Polyphenols and human health: prevention of disease and mechanisms of action. Nutrients (2010) 1.66
Prevalence of physical activity among Chinese adults: results from the International Collaborative Study of Cardiovascular Disease in Asia. Am J Public Health (2005) 1.63
Physical Activity and Risk of Coronary Heart Disease and Stroke in Older Adults: The Cardiovascular Health Study. Circulation (2015) 1.56
Association of Fitness in Young Adulthood With Survival and Cardiovascular Risk: The Coronary Artery Risk Development in Young Adults (CARDIA) Study. JAMA Intern Med (2016) 1.50
Impact of inactivity and exercise on the vasculature in humans. Eur J Appl Physiol (2009) 1.49
Changes in vascular hemodynamics in older women following 16 weeks of combined aerobic and resistance training. J Clin Hypertens (Greenwich) (2012) 1.42
Chocolate and prevention of cardiovascular disease: a systematic review. Nutr Metab (Lond) (2006) 1.40
Frequency, Type, and Volume of Leisure-Time Physical Activity and Risk of Coronary Heart Disease in Young Women. Circulation (2016) 1.39
Physical activity after diagnosis and risk of prostate cancer progression: data from the cancer of the prostate strategic urologic research endeavor. Cancer Res (2011) 1.38
Exercise training and cardiac rehabilitation in primary and secondary prevention of coronary heart disease. Mayo Clin Proc (2009) 1.33
Using built environment characteristics to predict walking for exercise. Int J Health Geogr (2008) 1.32
A prospective study of weight training and risk of type 2 diabetes mellitus in men. Arch Intern Med (2012) 1.23
The Claudication: Exercise Vs. Endoluminal Revascularization (CLEVER) study: rationale and methods. J Vasc Surg (2008) 1.22
Quantifying the dose-response of walking in reducing coronary heart disease risk: meta-analysis. Eur J Epidemiol (2009) 1.21
Invited commentary: Taking advantage of time-varying neighborhood environments. Am J Epidemiol (2014) 1.19
Walking for prevention of cardiovascular disease in men and women: a systematic review of observational studies. Obes Rev (2008) 1.18
Physical activity decreases diverticular complications. Am J Gastroenterol (2009) 1.16
Established risk factors account for most of the racial differences in cardiovascular disease mortality. PLoS One (2007) 1.12
Does active commuting improve psychological wellbeing? Longitudinal evidence from eighteen waves of the British Household Panel Survey. Prev Med (2014) 1.08
Vigorous-intensity leisure-time physical activity and risk of major chronic disease in men. Med Sci Sports Exerc (2012) 1.06
Physical Activity and Cardiovascular Disease: How Much is Enough? Am J Lifestyle Med (2009) 1.03
Association of self-reported physical activity with laboratory markers of nutrition and inflammation: the Comprehensive Dialysis Study. J Ren Nutr (2011) 1.02
Physical inactivity and mortality risk. Cardiol Res Pract (2011) 1.00
Adherence to heart-healthy behaviors in a sample of the U.S. population. Prev Chronic Dis (2005) 0.99
Novel risk factors for atrial fibrillation: useful for risk prediction and clinical decision making? Circulation (2012) 0.97
Physical activity, body mass index, and diabetes risk in men: a prospective study. Am J Med (2009) 0.96
Impact of walking on life expectancy and lifetime medical expenditure: the Ohsaki Cohort Study. BMJ Open (2011) 0.95
Measures of physical activity and their correlates: the Swedish National March Cohort. Eur J Epidemiol (2009) 0.94
Association of walking with survival and RRT among patients with CKD stages 3-5. Clin J Am Soc Nephrol (2014) 0.94
The association between physical activity and both incident coronary artery calcification and ankle brachial index progression: the multi-ethnic study of atherosclerosis. Atherosclerosis (2013) 0.93
Physical activity, health benefits, and mortality risk. ISRN Cardiol (2012) 0.93
Physical activity and the risk of incident atrial fibrillation in women. Circ Cardiovasc Qual Outcomes (2011) 0.90
Effects of resistance training on central blood pressure in obese young men. J Hum Hypertens (2013) 0.90
Physical activity of moderate intensity in leisure time and the risk of all cause mortality. Br J Sports Med (2005) 0.90
Leisure-Time Physical Activity and Cardiovascular Mortality in an Elderly Population in Northern Manhattan: A Prospective Cohort Study. J Gen Intern Med (2016) 0.88
Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin. Cardiovasc Res (2012) 0.88
Associations between multiple accelerometry-assessed physical activity parameters and selected health outcomes in elderly people--results from the KORA-age study. PLoS One (2014) 0.87
Association of objectively measured physical activity with cardiovascular risk in mobility-limited older adults. J Am Heart Assoc (2015) 0.86
Vascular Aging across the Menopause Transition in Healthy Women. Adv Vasc Med (2014) 0.86
The efficacy of a 9-month treadmill walking program on the exercise capacity and weight reduction for adolescents with severe autism. J Autism Dev Disord (2007) 0.85
Leisure-time physical activity and all-cause mortality. PLoS One (2014) 0.84
Metabolic syndrome and physical activity in southern Brazilian community-dwelling elders: a population-based, cross-sectional study. BMC Public Health (2009) 0.84
Speed and duration of walking and other leisure time physical activity and the risk of heart failure: a prospective cohort study from the Copenhagen City Heart Study. PLoS One (2014) 0.84
Perceived barriers to walking for physical activity. Prev Chronic Dis (2006) 0.83
Associations of Tai Chi, walking, and jogging with mortality in Chinese men. Am J Epidemiol (2013) 0.83
No pain, no gain? Thoughts on the Caerphilly study. Br J Sports Med (2004) 0.83
Economic evaluation of the direct healthcare cost savings resulting from the use of walking interventions to prevent coronary heart disease in Australia. Int J Health Care Finance Econ (2009) 0.82
Theory-based behavioral intervention increases self-reported physical activity in South African men: a cluster-randomized controlled trial. Prev Med (2014) 0.82
Modifying health behavior to prevent cardiovascular diseases: a nationwide survey among German primary care physicians. Int J Environ Res Public Health (2014) 0.82
Sports participation in patients with implantable cardioverter-defibrillators. Herzschrittmacherther Elektrophysiol (2012) 0.81
Telemetric analysis of haemodynamic regulation during voluntary exercise training in mouse models. Exp Physiol (2011) 0.81
High-intensity interval exercise and cerebrovascular health: curiosity, cause, and consequence. J Cereb Blood Flow Metab (2015) 0.80
Physical activity and inactivity and risk of hip fractures in men. Am J Public Health (2014) 0.80
Calcium handling proteins: structure, function, and modulation by exercise. Heart Fail Rev (2014) 0.79
The effect of leisure-time physical activity on the risk of acute myocardial infarction depending on body mass index: a population-based case-control study. BMC Public Health (2006) 0.79
Rating of perceived exertion as a tool for prescribing and self regulating interval training: a pilot study. Biol Sport (2015) 0.79
Effects of walking on medical cost: A quantitative evaluation by simulation focusing on diabetes. J Diabetes Investig (2013) 0.79
The association between resistance exercise and cardiovascular disease risk in women. J Sci Med Sport (2014) 0.78
Exercise and vascular function: how much is too much? Can J Physiol Pharmacol (2014) 0.78
Minor changes in blood lipids after 6 weeks of high-volume low- intensity physical activity with strict energy balance control. Eur J Appl Physiol (2005) 0.78
The impact of exercise consultation on activity levels and metabolic markers in obese adolescents: a pilot study. Int J Pediatr Endocrinol (2010) 0.78
Physical activity, genes for physical fitness, and risk of coronary heart disease. Med Sci Sports Exerc (2013) 0.77
Physical activity level and risk of death: the severance cohort study. J Epidemiol (2012) 0.77
Electrode position markedly affects knee torque in tetanic, stimulated contractions. Eur J Appl Physiol (2015) 0.77
Epidemiology, diagnosis, and management of atrial fibrillation in women. Int J Womens Health (2015) 0.77
Walking to work in Canada: health benefits, socio-economic characteristics and urban-regional variations. BMC Public Health (2011) 0.77
The relationship between walking speed and changes in cardiovascular risk factors during a 12-day walking tour to Santiago de Compostela: a cohort study. BMJ Open (2012) 0.77
Untrained young men have dysfunctional HDL compared with strength-trained men irrespective of body weight status. J Appl Physiol (1985) (2013) 0.76
Dispositional Mindfulness Predicts Adaptive Affective Responses to Health Messages and Increased Exercise Motivation. Mindfulness (N Y) (2016) 0.76
Hard exercise, affect lability, and personality among individuals with bulimia nervosa. Eat Behav (2013) 0.76
Targeting Lifestyle Behavior Change in Adults with NAFLD During a 20-min Consultation: Summary of the Dietary and Exercise Literature. Curr Gastroenterol Rep (2016) 0.76
Determination of metabolic equivalents during low- and high-intensity resistance exercise in healthy young subjects and patients with type 2 diabetes. Biol Sport (2016) 0.76
Daily physical activity and type 2 diabetes: A review. World J Diabetes (2016) 0.76
A longitudinal study examining the effects of a season of American football on lipids and lipoproteins. Lipids Health Dis (2015) 0.76
Exercise intensity and risk of coronary heart disease. JAMA (2003) 0.75
Relationship of weekly activity minutes to metabolic syndrome in prediabetes: the healthy living partnerships to prevent diabetes. J Phys Act Health (2012) 0.75
Cardiovascular disease following hematopoietic stem cell transplantation: Pathogenesis, detection, and the cardioprotective role of aerobic training. Crit Rev Oncol Hematol (2015) 0.75
Implementation of the 2013 American College of Cardiology/American Heart Association Blood Cholesterol Guideline Including Data From the Improved Reduction of Outcomes: Vytorin Efficacy International Trial. Rev Cardiovasc Med (2015) 0.75
Exercise intensity and risk of coronary heart disease. JAMA (2003) 0.75
Dietary predictors of early-onset ischaemic heart disease in a sample drawn from a Pakistani population. Heart Asia (2012) 0.75
Dyslipidemia in the Arabian Gulf and its Impact on Cardiovascular Risk Outcome. Oman Med J (2015) 0.75
MiR-222 in Cardiovascular Diseases: Physiology and Pathology. Biomed Res Int (2017) 0.75
Smoking and Physical Activity in Healthy Adults: A Cross-Sectional Study in Tehran. Tanaffos (2015) 0.75
Heart Wellness Programme: a pilot community-based cardiac rehabilitation programme in a multiethnic society. Singapore Med J (2016) 0.75
Lack of exercise of "moderate to vigorous" intensity in people with low levels of physical activity is a major discriminant for sociodemographic factors and morbidity. PLoS One (2014) 0.75
Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nat Genet (2008) 35.06
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat Genet (2010) 16.96
Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet (2008) 16.25
Overweight, obesity, and mortality in a large prospective cohort of persons 50 to 71 years old. N Engl J Med (2006) 16.17
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
A common genetic variant is associated with adult and childhood obesity. Science (2006) 14.95
Body-mass index and mortality among 1.46 million white adults. N Engl J Med (2010) 13.34
Intake of sugar-sweetened beverages and weight gain: a systematic review. Am J Clin Nutr (2006) 13.19
Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. N Engl J Med (2008) 12.41
Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med (2011) 12.29
Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA (2004) 11.69
Diabetes in Asia: epidemiology, risk factors, and pathophysiology. JAMA (2009) 11.52
Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr (2006) 10.95
Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA (2003) 10.05
A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med (2003) 9.24
The role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis. J Clin Endocrinol Metab (2007) 8.91
Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst (2004) 8.77
Adiposity as compared with physical activity in predicting mortality among women. N Engl J Med (2004) 8.63
Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis. Diabetes Care (2010) 8.52
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med (2008) 8.03
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA (2006) 7.73
Long-term colorectal-cancer incidence and mortality after lower endoscopy. N Engl J Med (2013) 7.72
The public health and economic benefits of taxing sugar-sweetened beverages. N Engl J Med (2009) 7.48
Plasma adiponectin levels and risk of myocardial infarction in men. JAMA (2004) 7.46
Short sleep duration and weight gain: a systematic review. Obesity (Silver Spring) (2008) 7.40
A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care (2003) 7.40
Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med (2002) 7.32
Optimal diets for prevention of coronary heart disease. JAMA (2002) 7.24
Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. J Natl Cancer Inst (2006) 7.19
Plasma 25-hydroxyvitamin D levels and risk of incident hypertension. Hypertension (2007) 6.99
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance. Am J Clin Nutr (2002) 6.96
Observational studies analyzed like randomized experiments: an application to postmenopausal hormone therapy and coronary heart disease. Epidemiology (2008) 6.87
Sugar-sweetened beverages, obesity, type 2 diabetes mellitus, and cardiovascular disease risk. Circulation (2010) 6.86
A pooled analysis of vitamin D dose requirements for fracture prevention. N Engl J Med (2012) 6.85
Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr (2005) 6.67
Trans fatty acids and cardiovascular disease. N Engl J Med (2006) 6.67
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet (2010) 6.66
Effect of Vitamin D on falls: a meta-analysis. JAMA (2004) 6.64
Cardiovascular morbidity and mortality in women diagnosed with rheumatoid arthritis. Circulation (2003) 6.62
Body-mass index and mortality among adults with incident type 2 diabetes. N Engl J Med (2014) 6.51
Meat intake and mortality: a prospective study of over half a million people. Arch Intern Med (2009) 6.42
A prospective study of sleep duration and mortality risk in women. Sleep (2004) 6.11
Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med (2012) 5.98
Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men. N Engl J Med (2003) 5.95
Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA (2005) 5.95
Vitamin D and risk of cause specific death: systematic review and meta-analysis of observational cohort and randomised intervention studies. BMJ (2014) 5.88
Inflammatory markers and the risk of coronary heart disease in men and women. N Engl J Med (2004) 5.86
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Major types of dietary fat and risk of coronary heart disease: a pooled analysis of 11 cohort studies. Am J Clin Nutr (2009) 5.79
Coffee consumption and risk for type 2 diabetes mellitus. Ann Intern Med (2004) 5.67
Correlates of long sleep duration. Sleep (2006) 5.67
Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials. Arch Intern Med (2009) 5.63
Alternative dietary indices both strongly predict risk of chronic disease. J Nutr (2012) 5.60
Dairy consumption and risk of type 2 diabetes mellitus in men: a prospective study. Arch Intern Med (2005) 5.59