Published in Circulation on March 11, 2003
Nurses' Health Study (Cardiovascular Component) | NCT00005152
Hydroxychloroquine to Improve Insulin Sensitivity in Rheumatoid Arthritis (RA PLUS) | NCT01132118
Effects of Abatacept on Myocarditis in Rheumatoid Arthritis (AMiRA) | NCT03619876
Enalapril Maleate on Arterial Stiffness in Rheumatoid Arthritis. | NCT03667131
Cardiovascular Profiles in Rheumatoid Arthritis (RA-HF) | NCT03960515
Patterns of cardiovascular risk in rheumatoid arthritis. Ann Rheum Dis (2006) 3.48
Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases. Arthritis Res Ther (2009) 3.47
Reduction in the incidence of myocardial infarction in patients with rheumatoid arthritis who respond to anti-tumor necrosis factor alpha therapy: results from the British Society for Rheumatology Biologics Register. Arthritis Rheum (2007) 3.34
Risk for cardiovascular disease early and late after a diagnosis of giant-cell arteritis: a cohort study. Ann Intern Med (2014) 2.76
Independent association of rheumatoid arthritis with increased left ventricular mass but not with reduced ejection fraction. Arthritis Rheum (2009) 2.33
Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study. Arthritis Res Ther (2006) 2.28
Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study. Arthritis Res Ther (2008) 2.15
Cardiovascular admissions and mortality in an inception cohort of patients with rheumatoid arthritis with onset in the 1980s and 1990s. Ann Rheum Dis (2005) 2.11
Rheumatoid Arthritis, Anti-Cyclic Citrullinated Peptide Positivity, and Cardiovascular Disease Risk in the Women's Health Initiative. Arthritis Rheumatol (2015) 2.07
Risk of atrial fibrillation and stroke in rheumatoid arthritis: Danish nationwide cohort study. BMJ (2012) 1.94
Cardiovascular morbidity and mortality in rheumatoid arthritis. Am J Med (2008) 1.77
Explaining the cardiovascular risk associated with rheumatoid arthritis: traditional risk factors versus markers of rheumatoid arthritis severity. Ann Rheum Dis (2010) 1.76
Increased incidence of cardiovascular disease in patients with rheumatoid arthritis: results from a community based study. Ann Rheum Dis (2004) 1.75
Cardiovascular, rheumatologic, and pharmacologic predictors of stroke in patients with rheumatoid arthritis: a nested, case-control study. Arthritis Rheum (2008) 1.73
Subclinical atherosclerosis in rheumatoid arthritis and systemic lupus erythematosus. Am J Med (2008) 1.70
Plasma carboxypeptidase B downregulates inflammatory responses in autoimmune arthritis. J Clin Invest (2011) 1.63
Molecular imaging of rheumatoid arthritis by radiolabelled monoclonal antibodies: new imaging strategies to guide molecular therapies. Eur J Nucl Med Mol Imaging (2009) 1.62
Diastolic heart function in RA patients. Rheumatol Int (2007) 1.59
Lipids and inflammation: serial measurements of the lipid profile of blood donors who later developed rheumatoid arthritis. Ann Rheum Dis (2006) 1.56
Integrated safety in tocilizumab clinical trials. Arthritis Res Ther (2011) 1.55
Carotid atherosclerosis predicts incident acute coronary syndromes in rheumatoid arthritis. Arthritis Rheum (2011) 1.49
Interpretation of observational studies. Heart (2004) 1.46
IL-17 and TNF-α sustain neutrophil recruitment during inflammation through synergistic effects on endothelial activation. J Immunol (2012) 1.44
Bisphosphonate use is associated with reduced risk of myocardial infarction in patients with rheumatoid arthritis. J Bone Miner Res (2013) 1.44
The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28. Arthritis Res Ther (2006) 1.43
Association of Triple Therapy With Improvement in Cholesterol Profiles Over Two-Year Followup in the Treatment of Early Aggressive Rheumatoid Arthritis Trial. Arthritis Rheumatol (2016) 1.42
Severe extra-articular disease manifestations are associated with an increased risk of first ever cardiovascular events in patients with rheumatoid arthritis. Ann Rheum Dis (2006) 1.42
Hypoxia--a key regulator of angiogenesis and inflammation in rheumatoid arthritis. Nat Rev Rheumatol (2012) 1.41
Biomarkers of endothelial dysfunction, cardiovascular risk factors and atherosclerosis in rheumatoid arthritis. Arthritis Res Ther (2005) 1.39
Rheumatoid arthritis is an independent risk factor for multi-vessel coronary artery disease: a case control study. Arthritis Res Ther (2005) 1.38
Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study. Arthritis Res Ther (2011) 1.35
Noncardiac vascular disease in rheumatoid arthritis: increase in venous thromboembolic events? Arthritis Rheum (2012) 1.34
Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment. Rheumatology (Oxford) (2014) 1.34
Why do people with rheumatoid arthritis still die prematurely? Ann Rheum Dis (2008) 1.28
Benefits of exercise in rheumatoid arthritis. J Aging Res (2011) 1.25
Traditional cardiovascular risk factors, inflammation and cardiovascular risk in rheumatoid arthritis. Rheumatology (Oxford) (2012) 1.24
Risk of diabetes among patients with rheumatoid arthritis, psoriatic arthritis and psoriasis. Ann Rheum Dis (2010) 1.21
Methotrexate modulates the kinetics of adenosine in humans in vivo. Ann Rheum Dis (2005) 1.18
Cardiovascular co-morbidity in rheumatic diseases. Vasc Health Risk Manag (2008) 1.16
The inextricable link between atherosclerosis and prototypical inflammatory diseases rheumatoid arthritis and systemic lupus erythematosus. Arthritis Res Ther (2009) 1.15
Correlation between endothelial function and carotid atherosclerosis in rheumatoid arthritis patients with long-standing disease. Arthritis Res Ther (2011) 1.14
Anti-tumour necrosis factor alpha therapy in rheumatoid arthritis: an update on safety. Ann Rheum Dis (2004) 1.14
Myocardial dysfunction in rheumatoid arthritis: epidemiology and pathogenesis. Arthritis Res Ther (2005) 1.13
Rheumatoid cachexia and cardiovascular disease. Nat Rev Rheumatol (2010) 1.11
Cardiovascular comorbidity in rheumatic diseases. Nat Rev Rheumatol (2015) 1.11
Is cumulative exposure to economic hardships more hazardous to women's health than men's? A 16-year follow-up study of the Swedish Survey of Living Conditions. J Epidemiol Community Health (2007) 1.10
Levels of C-reactive protein associated with high and very high cardiovascular risk are prevalent in patients with rheumatoid arthritis. PLoS One (2009) 1.09
Atherogenic lipid profiles and its management in patients with rheumatoid arthritis. Vasc Health Risk Manag (2007) 1.08
Cutaneous markers of coronary artery disease. World J Cardiol (2010) 1.07
Disease activity in rheumatoid arthritis and the risk of cardiovascular events. Arthritis Rheumatol (2015) 1.06
No increased risk of myocardial infarction among patients with ulcerative colitis or Crohn's disease. Clin Gastroenterol Hepatol (2011) 1.05
Non-steroidal anti-inflammatory drug use does not appear to be associated with increased cardiovascular mortality in patients with inflammatory polyarthritis: results from a primary care based inception cohort of patients. Ann Rheum Dis (2008) 1.05
Cardiovascular disease in patients with chronic inflammation: mechanisms underlying premature cardiovascular events in rheumatologic conditions. Eur Heart J (2014) 1.04
The influence of age at symptom onset and length of followup on mortality in patients with recent-onset inflammatory polyarthritis. Arthritis Rheum (2008) 1.04
Vascular effects of biologic agents in RA and spondyloarthropathies. Nat Rev Rheumatol (2009) 1.04
Rheumatoid arthritis prevalence, incidence, and mortality rates: a nationwide population study in Taiwan. Rheumatol Int (2012) 1.02
Cardiovascular risk in rheumatoid arthritis: comparing TNF-α blockade with nonbiologic DMARDs. Am J Med (2013) 1.01
Effect of rheumatoid factor on mortality and coronary heart disease. Ann Rheum Dis (2009) 1.01
Risk of subsequent ischemic and hemorrhagic stroke in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden. BMC Neurol (2012) 1.01
The role of endothelial function and its assessment in rheumatoid arthritis. Nat Rev Rheumatol (2010) 1.01
Physical activity measured by the SenseWear Armband in women with rheumatoid arthritis. Phys Ther (2011) 1.00
Statin treatment for rheumatoid arthritis: a promising novel indication. Clin Rheumatol (2007) 1.00
Management of cardiovascular disease risk in chronic inflammatory disorders. Nat Rev Rheumatol (2009) 0.98
Atherosclerosis and inflammation: insights from rheumatoid arthritis. Clin Rheumatol (2007) 0.98
A comparative study of arterial stiffness, flow-mediated vasodilation of the brachial artery, and the thickness of the carotid artery intima-media in patients with systemic autoimmune diseases. Clin Rheumatol (2009) 0.98
Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals. Arthritis Res Ther (2012) 0.97
Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis. Arthritis Res Ther (2012) 0.97
Data-driven identification of co-morbidities associated with rheumatoid arthritis in a large US health plan claims database. BMC Musculoskelet Disord (2010) 0.97
Assessment of myocardial abnormalities in rheumatoid arthritis using a comprehensive cardiac magnetic resonance approach: a pilot study. Arthritis Res Ther (2010) 0.95
Adipokines, inflammation, insulin resistance, and carotid atherosclerosis in patients with rheumatoid arthritis. Arthritis Res Ther (2013) 0.95
The impact of traditional cardiovascular risk factors on cardiovascular outcomes in patients with rheumatoid arthritis: a systematic review and meta-analysis. PLoS One (2015) 0.95
Risk of subsequent coronary heart disease in patients hospitalized for immune-mediated diseases: a nationwide follow-up study from Sweden. PLoS One (2012) 0.94
The association between reduction in inflammation and changes in lipoprotein levels and HDL cholesterol efflux capacity in rheumatoid arthritis. J Am Heart Assoc (2015) 0.94
Cardiovascular safety of biologic therapies for the treatment of RA. Nat Rev Rheumatol (2011) 0.92
Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken) (2013) 0.92
Patterns of preventive health services in rheumatoid arthritis patients compared to a primary care patient population. Rheumatol Int (2010) 0.92
Association between metabolic syndrome, BMI, and serum vitamin D concentrations in rheumatoid arthritis. Clin Rheumatol (2012) 0.92
Atherosclerosis and rheumatoid arthritis: more than a simple association. Mediators Inflamm (2012) 0.92
HIV and aging: emerging research issues. Curr Opin HIV AIDS (2014) 0.91
Longterm outcomes and treatment after myocardial infarction in patients with rheumatoid arthritis. J Rheumatol (2013) 0.91
Extra-articular Manifestations in Rheumatoid Arthritis. Maedica (Buchar) (2010) 0.91
Prothrombotic effects of tumor necrosis factor alpha in vivo are amplified by the absence of TNF-alpha receptor subtype 1 and require TNF-alpha receptor subtype 2. Arthritis Res Ther (2012) 0.91
Cardiorheumatology: cardiac involvement in systemic rheumatic disease. Nat Rev Cardiol (2014) 0.91
Rheumatoid arthritis patients receive less frequent acute reperfusion and secondary prevention therapy after myocardial infarction compared with the general population. Arthritis Res Ther (2010) 0.91
Lack of cardiovascular risk assessment in inflammatory arthritis and systemic lupus erythematosus patients at a tertiary care center. Clin Rheumatol (2011) 0.90
Rheumatoid arthritis, periodontal disease and coronary artery disease. Clin Rheumatol (2007) 0.90
Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study. Arthritis Res Ther (2008) 0.90
Management of rheumatoid arthritis: consensus recommendations from the Hong Kong Society of Rheumatology. Clin Rheumatol (2010) 0.90
Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS One (2015) 0.89
Cardiovascular disease in rheumatoid arthritis: a systematic literature review in latin america. Arthritis (2012) 0.89
Rheumatoid factor and anti-citrullinated protein antibody positivity, but not level, are associated with increased mortality in patients with rheumatoid arthritis: results from two large independent cohorts. Arthritis Res Ther (2014) 0.89
The association between disease activity and NT-proBNP in 238 patients with rheumatoid arthritis: a 10-year longitudinal study. Arthritis Res Ther (2008) 0.88
High-density lipoprotein cholesterol subfractions HDL2 and HDL3 are reduced in women with rheumatoid arthritis and may augment the cardiovascular risk of women with RA: a cross-sectional study. Arthritis Res Ther (2012) 0.88
Rheumatoid arthritis and cardiovascular disease: an update on treatment issues. Curr Opin Rheumatol (2013) 0.87
Infliximab, a TNF-α inhibitor, reduces 24-h ambulatory blood pressure in rheumatoid arthritis patients. J Hum Hypertens (2013) 0.87
Asthma predicts cardiovascular disease events: the multi-ethnic study of atherosclerosis. Arterioscler Thromb Vasc Biol (2015) 0.87
Risk of venous thromboembolism in patients with rheumatoid arthritis. Arthritis Care Res (Hoboken) (2013) 0.87
The peroxisome proliferator activated receptor-γ pioglitazone improves vascular function and decreases disease activity in patients with rheumatoid arthritis. J Am Heart Assoc (2013) 0.86
Coagulation and the fibrin network in rheumatic disease: a role beyond haemostasis. Nat Rev Rheumatol (2012) 0.86
The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab (2010) 13.29
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 12.44
Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. N Engl J Med (2008) 12.41
Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med (2011) 12.29
Calcium plus vitamin D supplementation and the risk of fractures. N Engl J Med (2006) 12.09
Sugar-sweetened beverages, weight gain, and incidence of type 2 diabetes in young and middle-aged women. JAMA (2004) 11.69
Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA (2007) 10.50
Television watching and other sedentary behaviors in relation to risk of obesity and type 2 diabetes mellitus in women. JAMA (2003) 10.05
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat Genet (2010) 9.90
A prospective study of sleep duration and coronary heart disease in women. Arch Intern Med (2003) 9.24
Time trends in reported prevalence of kidney stones in the United States: 1976-1994. Kidney Int (2003) 9.11
Low-dose aspirin in the primary prevention of cancer: the Women's Health Study: a randomized controlled trial. JAMA (2005) 9.03
Two independent alleles at 6q23 associated with risk of rheumatoid arthritis. Nat Genet (2007) 8.74
Calcium plus vitamin D supplementation and the risk of colorectal cancer. N Engl J Med (2006) 8.73
Adiposity as compared with physical activity in predicting mortality among women. N Engl J Med (2004) 8.63
Vitamins E and C in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 8.32
25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study. Arch Intern Med (2008) 8.03
Fish intake, contaminants, and human health: evaluating the risks and the benefits. JAMA (2006) 7.73
Plasma adiponectin levels and risk of myocardial infarction in men. JAMA (2004) 7.46
A prospective study of self-reported sleep duration and incident diabetes in women. Diabetes Care (2003) 7.40
Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med (2002) 7.32
Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. J Natl Cancer Inst (2006) 7.19
Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA (2010) 7.12
Common variants at CD40 and other loci confer risk of rheumatoid arthritis. Nat Genet (2008) 7.07
Plasma 25-hydroxyvitamin D levels and risk of incident hypertension. Hypertension (2007) 6.99
Diet quality and major chronic disease risk in men and women: moving toward improved dietary guidance. Am J Clin Nutr (2002) 6.96
Comparison of abdominal adiposity and overall obesity in predicting risk of type 2 diabetes among men. Am J Clin Nutr (2005) 6.67
Trans fatty acids and cardiovascular disease. N Engl J Med (2006) 6.67
Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol (2006) 6.66
Calcium/vitamin D supplementation and cardiovascular events. Circulation (2007) 6.63
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4. Am J Hum Genet (2005) 6.61
Accuracy of Medicare claims-based diagnosis of acute myocardial infarction: estimating positive predictive value on the basis of review of hospital records. Am Heart J (2004) 6.57
Purine-rich foods, dairy and protein intake, and the risk of gout in men. N Engl J Med (2004) 6.53
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial. JAMA (2006) 6.51
Body-mass index and mortality among adults with incident type 2 diabetes. N Engl J Med (2014) 6.51
Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: Meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med (2010) 6.48
Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement. Kidney Int (2004) 6.32
Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med (2009) 6.16
A prospective study of sleep duration and mortality risk in women. Sleep (2004) 6.11
Surgery versus physical therapy for a meniscal tear and osteoarthritis. N Engl J Med (2013) 6.08
Sugar-sweetened beverages and genetic risk of obesity. N Engl J Med (2012) 5.98
Roles of drinking pattern and type of alcohol consumed in coronary heart disease in men. N Engl J Med (2003) 5.95
Inflammatory markers and the risk of coronary heart disease in men and women. N Engl J Med (2004) 5.86
Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial. JAMA (2006) 5.75
Coffee consumption and risk for type 2 diabetes mellitus. Ann Intern Med (2004) 5.67
Alternative dietary indices both strongly predict risk of chronic disease. J Nutr (2012) 5.60
Dairy consumption and risk of type 2 diabetes mellitus in men: a prospective study. Arch Intern Med (2005) 5.59
New loci associated with kidney function and chronic kidney disease. Nat Genet (2010) 5.58
Obesity, weight gain, and the risk of kidney stones. JAMA (2005) 5.34
Multivitamins in the prevention of cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 5.25
Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): a post-hoc analysis of a randomised controlled trial. Lancet (2009) 5.22
Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial. JAMA (2008) 5.13
Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular events. Ann Intern Med (2010) 5.05
Validity of International Classification of Diseases, Ninth Revision, Clinical Modification Codes for Acute Renal Failure. J Am Soc Nephrol (2006) 4.95
Physical activity, including walking, and cognitive function in older women. JAMA (2004) 4.90
Urologic diseases in America project: urolithiasis. J Urol (2005) 4.90
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Effects of estrogen plus progestin on health-related quality of life. N Engl J Med (2003) 4.83
Breast cancer after use of estrogen plus progestin in postmenopausal women. N Engl J Med (2009) 4.80
Red meat consumption and mortality: results from 2 prospective cohort studies. Arch Intern Med (2012) 4.72
Exercise type and intensity in relation to coronary heart disease in men. JAMA (2002) 4.69
Inflammatory markers and risk of developing type 2 diabetes in women. Diabetes (2004) 4.67
Vasectomy and risk of aggressive prostate cancer: a 24-year follow-up study. J Clin Oncol (2014) 4.67
Merging and emerging cohorts: not worth the wait. Nature (2007) 4.66
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies. Lancet (2012) 4.63
SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression. Nature (2011) 4.57
Dietary fat and meat intake in relation to risk of type 2 diabetes in men. Diabetes Care (2002) 4.48
Habitual caffeine intake and the risk of hypertension in women. JAMA (2005) 4.46
Health risks and benefits 3 years after stopping randomized treatment with estrogen and progestin. JAMA (2008) 4.42
Sexual function in men older than 50 years of age: results from the health professionals follow-up study. Ann Intern Med (2003) 4.40
Multivitamins in the prevention of cardiovascular disease in men: the Physicians' Health Study II randomized controlled trial. JAMA (2012) 4.40
Glycemic index, glycemic load, and dietary fiber intake and incidence of type 2 diabetes in younger and middle-aged women. Am J Clin Nutr (2004) 4.29
Dietary patterns, meat intake, and the risk of type 2 diabetes in women. Arch Intern Med (2004) 4.27
Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men. Circulation (2012) 4.24
Leukocyte count as a predictor of cardiovascular events and mortality in postmenopausal women: the Women's Health Initiative Observational Study. Arch Intern Med (2005) 4.24