Published in Immunity on October 01, 2002
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Cytokine signaling modules in inflammatory responses. Immunity (2008) 4.09
CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature (2013) 4.04
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood (2005) 3.76
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CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. J Clin Invest (2010) 2.38
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G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells. Blood (2006) 1.76
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Elevating body temperature enhances hematopoiesis and neutrophil recovery after total body irradiation in an IL-1-, IL-17-, and G-CSF-dependent manner. Blood (2012) 1.46
Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression. Cancer Cell (2014) 1.45
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Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection. Blood (2006) 1.06
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Kinetics of neutrophils in mice exposed to radiation and/or granulocyte colony-stimulating factor treatment. Radiat Res (2013) 1.01
Neutrophils control the magnitude and spread of the immune response in a thromboxane A2-mediated process. J Exp Med (2013) 1.01
Intrapulmonary G-CSF rescues neutrophil recruitment to the lung and neutrophil release to blood in Gram-negative bacterial infection in MCP-1-/- mice. J Immunol (2012) 0.99
Neutrophil roles in left ventricular remodeling following myocardial infarction. Fibrogenesis Tissue Repair (2013) 0.99
Alcohol suppresses the granulopoietic response to pulmonary Streptococcus pneumoniae infection with enhancement of STAT3 signaling. J Immunol (2011) 0.98
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Localized bacterial infection induces systemic activation of neutrophils through Cxcr2 signaling in zebrafish. J Leukoc Biol (2013) 0.98
Depletion of dendritic cells enhances innate anti-bacterial host defense through modulation of phagocyte homeostasis. PLoS Pathog (2012) 0.98
Neonatal sepsis and neutrophil insufficiencies. Int Rev Immunol (2010) 0.96
FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood (2006) 0.93
Type I interferon signaling regulates the composition of inflammatory infiltrates upon infection with Listeria monocytogenes. Cell Immunol (2011) 0.92
Enhanced neutrophil motility by granulocyte colony-stimulating factor: the role of extracellular signal-regulated kinase and phosphatidylinositol 3-kinase. Immunology (2006) 0.91
Granulocyte colony-stimulating factor protects mice during respiratory virus infections. PLoS One (2012) 0.90
STAT5 is an ambivalent regulator of neutrophil homeostasis. PLoS One (2007) 0.90
Alcohol impairs the myeloid proliferative response to bacteremia in mice by inhibiting the stem cell antigen-1/ERK pathway. J Immunol (2012) 0.87
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Primary structure and antibacterial activity of chicken bone marrow-derived beta-defensins. Antimicrob Agents Chemother (2009) 0.86
Human regulatory T cells of G-CSF mobilized allogeneic stem cell donors qualify for clinical application. PLoS One (2012) 0.86
Overexpression of protein kinase C-{epsilon} in the mouse epidermis leads to a spontaneous myeloproliferative-like disease. Am J Pathol (2005) 0.85
ATP-binding cassette transporter 1 attenuates ovalbumin-induced neutrophilic airway inflammation. Am J Respir Cell Mol Biol (2014) 0.84
Neutrophil migration under normal and sepsis conditions. Cardiovasc Hematol Disord Drug Targets (2015) 0.83
Central role of conventional dendritic cells in regulation of bone marrow release and survival of neutrophils. J Immunol (2014) 0.82
The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts. Am J Pathol (2008) 0.82
Endothelial CD36 Contributes to Postischemic Brain Injury by Promoting Neutrophil Activation via CSF3. J Neurosci (2015) 0.82
Innate immune regulation by STAT-mediated transcriptional mechanisms. Immunol Rev (2014) 0.81
Giardia duodenalis infection reduces granulocyte infiltration in an in vivo model of bacterial toxin-induced colitis and attenuates inflammation in human intestinal tissue. PLoS One (2014) 0.81
Improved antibacterial host defense and altered peripheral granulocyte homeostasis in mice lacking the adhesion class G protein receptor CD97. Infect Immun (2006) 0.81
Early sensing of Yersinia pestis airway infection by bone marrow cells. Front Cell Infect Microbiol (2012) 0.80
G-CSF is a key modulator of MDSC and could be a potential therapeutic target in colitis-associated colorectal cancers. Protein Cell (2016) 0.80
Depletion of CD11c(+) cells in the CD11c.DTR model drives expansion of unique CD64(+) Ly6C(+) monocytes that are poised to release TNF-α. Eur J Immunol (2015) 0.78
Mobilization without immune depletion fails to restore immunological tolerance or preserve beta cell function in recent onset type 1 diabetes. Clin Exp Immunol (2015) 0.78
The Src homology-2 protein Shb modulates focal adhesion kinase signaling in a BCR-ABL myeloproliferative disorder causing accelerated progression of disease. J Hematol Oncol (2014) 0.78
The feasibility of in vivo imaging of infiltrating blood cells for predicting the functional prognosis after spinal cord injury. Sci Rep (2016) 0.78
G-CSF activation of AKT is not sufficient to prolong neutrophil survival. J Leukoc Biol (2013) 0.78
G-CSF-activated STAT3 enhances production of the chemokine MIP-2 in bone marrow neutrophils. J Leukoc Biol (2012) 0.78
G-CSF/anti-G-CSF antibody complexes drive the potent recovery and expansion of CD11b+Gr-1+ myeloid cells without compromising CD8+ T cell immune responses. J Hematol Oncol (2013) 0.78
Absence of CD9 reduces endometrial VEGF secretion and impairs uterine repair after parturition. Sci Rep (2014) 0.78
Regulatory Interactions in the Bone Marrow Microenvironment. IBMS Bonekey (2015) 0.77
G-CSF maintains controlled neutrophil mobilization during acute inflammation by negatively regulating CXCR2 signaling. J Exp Med (2016) 0.77
Activation of the aryl hydrocarbon receptor during development enhances the pulmonary CD4+ T-cell response to viral infection. Am J Physiol Lung Cell Mol Physiol (2015) 0.77
Macrophage-derived IL-1β enhances monosodium urate crystal-triggered NET formation. Inflamm Res (2016) 0.76
Neutrophil-mediated inflammation in the pathogenesis of Clostridium difficile infections. Anaerobe (2016) 0.76
The Essential Role of Neutrophils during Infection with the Intracellular Bacterial Pathogen Listeria monocytogenes. J Immunol (2016) 0.76
Neutrophil Dysfunction in Sepsis. Chin Med J (Engl) (2016) 0.75
Tpl2 promotes neutrophil trafficking, oxidative burst, and bacterial killing. J Leukoc Biol (2017) 0.75
Neutropenic sepsis is associated with distinct clinical and biological characteristics: a cohort study of severe sepsis. Crit Care (2016) 0.75
A novel murine model of Clostridium sordellii myonecrosis: Insights into the pathogenesis of disease. Anaerobe (2016) 0.75
The Essential Role of Type I Interferons in Differentiation and Activation of Tumor-Associated Neutrophils. Front Immunol (2016) 0.75
A late-lineage murine neutrophil precursor population exhibits dynamic changes during demand-adapted granulopoiesis. Sci Rep (2017) 0.75
Frontline Science: Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation. J Leukoc Biol (2016) 0.75
Neutrophils as protagonists and targets in chronic inflammation. Nat Rev Immunol (2017) 0.75
Dose-Dependent Suppression of Cytokine production from T cells by a Novel Phosphoinositide 3-Kinase Delta Inhibitor. Sci Rep (2016) 0.75
Mathematical model of stem cell differentiation and tissue regeneration with stochastic noise. Bull Math Biol (2014) 0.75
Granulocyte colony-stimulating factor blockade enables dexamethasone to inhibit lipopolysaccharide-induced murine lung neutrophils. PLoS One (2017) 0.75
FOXO1 Regulates Bacteria-Induced Neutrophil Activity. Front Immunol (2017) 0.75
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature (2008) 38.13
Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med (2009) 33.09
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing. Nature (2012) 14.33
DNMT3A mutations in acute myeloid leukemia. N Engl J Med (2010) 14.07
The origin and evolution of mutations in acute myeloid leukemia. Cell (2012) 9.66
Clonal architecture of secondary acute myeloid leukemia. N Engl J Med (2012) 6.71
Acquired copy number alterations in adult acute myeloid leukemia genomes. Proc Natl Acad Sci U S A (2009) 4.17
Use of whole-genome sequencing to diagnose a cryptic fusion oncogene. JAMA (2011) 4.11
CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature (2013) 4.04
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet (2011) 4.02
Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia. Blood (2008) 3.89
G-CSF potently inhibits osteoblast activity and CXCL12 mRNA expression in the bone marrow. Blood (2005) 3.76
The number of endothelial progenitor cell colonies in the blood is increased in patients with angiographically significant coronary artery disease. J Am Coll Cardiol (2006) 3.17
Rapid mobilization of functional donor hematopoietic cells without G-CSF using AMD3100, an antagonist of the CXCR4/SDF-1 interaction. Blood (2008) 3.11
High throughput digital quantification of mRNA abundance in primary human acute myeloid leukemia samples. J Clin Invest (2009) 2.66
Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth. Nat Med (2010) 2.44
CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. J Clin Invest (2010) 2.38
Suppression of CXCL12 production by bone marrow osteoblasts is a common and critical pathway for cytokine-induced mobilization. Blood (2009) 2.25
STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils. Blood (2006) 2.12
Characterization of hematopoietic progenitor mobilization in protease-deficient mice. Blood (2004) 2.01
Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice. J Exp Med (2011) 1.96
Mutations of the ELA2 gene found in patients with severe congenital neutropenia induce the unfolded protein response and cellular apoptosis. Blood (2007) 1.92
Regulation of neutrophil homeostasis. Curr Opin Hematol (2007) 1.87
CXCR4 is a key regulator of neutrophil release from the bone marrow under basal and stress granulopoiesis conditions. Blood (2009) 1.83
Next-generation sequencing identifies the natural killer cell microRNA transcriptome. Genome Res (2010) 1.75
A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes. Proc Natl Acad Sci U S A (2003) 1.69
G-CSF and AMD3100 mobilize monocytes into the blood that stimulate angiogenesis in vivo through a paracrine mechanism. Blood (2006) 1.66
Prevalence of mutations in ELANE, GFI1, HAX1, SBDS, WAS and G6PC3 in patients with severe congenital neutropenia. Br J Haematol (2009) 1.59
Mutations of the SBDS gene are present in most patients with Shwachman-Diamond syndrome. Blood (2004) 1.58
A mouse-based strategy for cyclophosphamide pharmacogenomic discovery. J Appl Physiol (1985) (2003) 1.55
Identification of somatic JAK1 mutations in patients with acute myeloid leukemia. Blood (2007) 1.55
Mechanisms of mobilization of hematopoietic progenitors with granulocyte colony-stimulating factor. Curr Opin Hematol (2002) 1.48
Pivotal role of granulocyte colony-stimulating factor in the development of progenitors in the common myeloid pathway. Blood (2003) 1.44
Granulocyte colony-stimulating factor induces osteoblast apoptosis and inhibits osteoblast differentiation. J Bone Miner Res (2008) 1.42
Genomics of AML: clinical applications of next-generation sequencing. Hematology Am Soc Hematol Educ Program (2011) 1.41
Csf3r mutations in mice confer a strong clonal HSC advantage via activation of Stat5. J Clin Invest (2008) 1.41
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The many causes of severe congenital neutropenia. N Engl J Med (2009) 1.40
Neutrophil elastase mutations and risk of leukaemia in severe congenital neutropenia. Br J Haematol (2007) 1.37
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N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells. Blood (2012) 1.33
Angiogenic cells can be rapidly mobilized and efficiently harvested from the blood following treatment with AMD3100. Blood (2006) 1.29
Lentiviral-mediated RNAi inhibition of Sbds in murine hematopoietic progenitors impairs their hematopoietic potential. Blood (2007) 1.25
Activation of Tyk2 and Stat3 is required for the apoptotic actions of interferon-beta in primary pro-B cells. J Biol Chem (2006) 1.23
Recruitment of the inflammatory subset of monocytes to sites of ischemia induces angiogenesis in a monocyte chemoattractant protein-1-dependent fashion. J Leukoc Biol (2008) 1.20
Contribution of granulocyte colony-stimulating factor to the acute mobilization of endothelial precursor cells by vascular disrupting agents. Cancer Res (2009) 1.20
Commonly dysregulated genes in murine APL cells. Blood (2006) 1.18
Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy. Br J Haematol (2010) 1.17
A truncation mutant of Csf3r cooperates with PML-RARα to induce acute myeloid leukemia in mice. Exp Hematol (2011) 1.17
Regulation of hematopoietic stem cell activity by inflammation. Front Immunol (2013) 1.17
Complete characterization of the microRNAome in a patient with acute myeloid leukemia. Blood (2010) 1.16
Mice expressing a neutrophil elastase mutation derived from patients with severe congenital neutropenia have normal granulopoiesis. Blood (2002) 1.09
Src family kinases are important negative regulators of G-CSF-dependent granulopoiesis. Blood (2006) 1.07
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection. Blood (2006) 1.06
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Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer. Cancer Immunol Immunother (2014) 0.96
Activation of the unfolded protein response is associated with impaired granulopoiesis in transgenic mice expressing mutant Elane. Blood (2011) 0.93
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Kruppel-like factor 7 overexpression suppresses hematopoietic stem and progenitor cell function. Blood (2012) 0.90
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Systemic levels of G-CSF and interleukin-6 determine the angiogenic potential of bone marrow resident monocytes. J Leukoc Biol (2010) 0.86
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Niche competition and cancer metastasis to bone. J Clin Invest (2011) 0.85
Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon. Blood (2013) 0.84
Cellular complexity of the bone marrow hematopoietic stem cell niche. Calcif Tissue Int (2013) 0.80
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G-CSF induced progenitor mobilization in mice with PIGA- blood cells. Hematol J (2004) 0.78
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