Published in Hum Genet on April 26, 2006
Genetic susceptibility to lymphoma. Haematologica (2007) 2.03
Roles of Werner syndrome protein in protection of genome integrity. DNA Repair (Amst) (2010) 1.82
The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis. Hum Genet (2008) 1.48
Current understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessment. Carcinogenesis (2011) 1.26
Association between the ERCC5 Asp1104His polymorphism and cancer risk: a meta-analysis. PLoS One (2012) 0.99
Association of BRCA2 N372H polymorphism with cancer susceptibility: a comprehensive review and meta-analysis. Sci Rep (2014) 0.89
Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma in a pooled analysis of three studies. Br J Haematol (2010) 0.89
Werner syndrome protein, WRN, protects cells from DNA damage induced by the benzene metabolite hydroquinone. Toxicol Sci (2008) 0.88
Depletion of WRN enhances DNA damage in HeLa cells exposed to the benzene metabolite, hydroquinone. Mutat Res (2007) 0.87
Integrative analysis of cancer prognosis data with multiple subtypes using regularized gradient descent. Genet Epidemiol (2012) 0.87
Survival patterns among lymphoma patients with a family history of lymphoma. J Clin Oncol (2008) 0.86
WRN Mutation Update: Mutation Spectrum, Patient Registries, and Translational Prospects. Hum Mutat (2016) 0.86
Association between the PARP1 Val762Ala polymorphism and cancer risk: evidence from 43 studies. PLoS One (2014) 0.85
Association between PARP-1 V762A polymorphism and cancer susceptibility: a meta-analysis. Genet Epidemiol (2011) 0.85
Genetic polymorphisms in DNA repair genes as modulators of Hodgkin disease risk. Cancer (2009) 0.83
Association between the XPG Asp1104His and XPF Arg415Gln polymorphisms and risk of cancer: a meta-analysis. PLoS One (2014) 0.83
Occupational solvent exposure, genetic variation of DNA repair genes, and the risk of non-Hodgkin's lymphoma. Eur J Cancer Prev (2012) 0.81
Polymorphisms in DNA repair pathway genes, body mass index, and risk of non-Hodgkin lymphoma. Am J Hematol (2013) 0.81
Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. Occup Environ Med (2009) 0.81
PARP-1 Val762Ala polymorphism is associated with reduced risk of non-Hodgkin lymphoma in Korean males. BMC Med Genet (2010) 0.80
SHMT1 C1420T polymorphism contributes to the risk of non-Hodgkin lymphoma: evidence from 7309 patients. Chin J Cancer (2015) 0.79
Host genetics in follicular lymphoma. Best Pract Res Clin Haematol (2011) 0.79
A new method to detect loss of heterozygosity using cohort heterozygosity comparisons. BMC Cancer (2010) 0.79
Association of the Asp312Asn and Lys751Gln polymorphisms in the XPD gene with the risk of non-Hodgkin's lymphoma: evidence from a meta-analysis. Chin J Cancer (2015) 0.78
Association of LIG4 and XRCC4 gene polymorphisms with the risk of human glioma in a Chinese population. Int J Clin Exp Pathol (2015) 0.78
A missense single nucleotide polymorphism, V114I of the Werner syndrome gene, is associated with risk of osteoporosis and femoral fracture in the Japanese population. J Bone Miner Metab (2015) 0.78
Polymorphisms of DNA repair and oxidative stress genes in B-cell lymphoma patients. Biomed Rep (2012) 0.77
Genetic variation in DNA repair pathways and risk of non-Hodgkin's lymphoma. PLoS One (2014) 0.77
Polymorphisms in DNA repair genes and MDR1 and the risk for non-Hodgkin lymphoma. Int J Mol Sci (2014) 0.77
PARP-1 Val762Ala polymorphism and risk of cancer: a meta-analysis based on 39 case-control studies. PLoS One (2014) 0.77
The association between RAD23B Ala249Val polymorphism and cancer susceptibility: evidence from a meta-analysis. PLoS One (2014) 0.77
Association of IL10 -819C>T and -592C>A Polymorphisms with Non-Hodgkin Lymphoma Susceptibility: Evidence from Published Studies. J Cancer (2015) 0.76
DNA repair deficiency as a susceptibility marker for spontaneous lymphoma in golden retriever dogs: a case-control study. PLoS One (2013) 0.75
WRN Cys1367Arg polymorphism is not associated with skull base chordoma. Biomed Rep (2014) 0.75
Different non-synonymous polymorphisms modulate the interaction of the WRN protein to its protein partners and its enzymatic activities. Oncotarget (2016) 0.75
Polymorphisms in DNA repair genes, hair dye use, and the risk of non-Hodgkin lymphoma. Cancer Causes Control (2014) 0.75
Predicting deleterious amino acid substitutions. Genome Res (2001) 28.95
Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst (2004) 19.00
Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation. Am J Hum Genet (2002) 4.29
SNP500Cancer: a public resource for sequence validation and assay development for genetic variation in candidate genes. Nucleic Acids Res (2004) 3.47
Collection of genomic DNA from adults in epidemiological studies by buccal cytobrush and mouthwash. Cancer Epidemiol Biomarkers Prev (2001) 3.40
Mechanisms of human DNA repair: an update. Toxicology (2003) 2.24
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome. Mol Cell (2005) 1.89
Genetic variation and willingness to participate in epidemiologic research: data from three studies. Cancer Epidemiol Biomarkers Prev (2005) 1.66
Current advances in unraveling the function of the Werner syndrome protein. Mutat Res (2005) 1.32
Alcohol use and risk of non-Hodgkin's lymphoma among Connecticut women (United States). Cancer Causes Control (2003) 1.26
Reduced expression levels of nucleotide excision repair genes in lung cancer: a case-control analysis. Carcinogenesis (2000) 1.26
Epidemiology of the Revised European-American Lymphoma Classification subtypes. Epidemiol Rev (1998) 1.18
Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population. Am J Med Genet (1997) 1.17
Variant XRCC3 implicated in cancer is functional in homology-directed repair of double-strand breaks. Oncogene (2002) 1.15
The enzymatic activities of the Werner syndrome protein are disabled by the amino acid polymorphism R834C. J Biol Chem (2004) 1.08
Analysis of gene expression profiles associated with cisplatin resistance in human ovarian cancer cell lines and tissues using cDNA microarray. Hum Cell (2001) 1.08
XRCC3 deficiency results in a defect in recombination and increased endoreduplication in human cells. EMBO J (2004) 1.07
Single nucleotide polymorphisms in the XPG gene: determination of role in DNA repair and breast cancer risk. Int J Cancer (2003) 1.06
Expression of nucleotide excision repair genes and the risk for squamous cell carcinoma of the head and neck. Cancer (2002) 1.06
Polymorphisms at the Werner locus: II. 1074Leu/Phe, 1367Cys/Arg, longevity, and atherosclerosis. Am J Med Genet (2000) 1.04
Recurring chromosomal abnormalities in non-Hodgkin's lymphoma: biologic and clinical significance. Semin Hematol (2000) 0.98
Cellular dynamics and modulation of WRN protein is DNA damage specific. Mech Ageing Dev (2005) 0.95
Characterization of the nuclear localization signal in the DNA helicase involved in Werner's syndrome. Int J Mol Med (1998) 0.94
Severe growth retardation and short life span of double-mutant mice lacking Xpa and exon 15 of Xpg. DNA Repair (Amst) (2005) 0.94
Dysregulation of DNA repair pathways in a transforming growth factor alpha/c-myc transgenic mouse model of accelerated hepatocarcinogenesis. Lab Invest (2003) 0.91
Mechanisms of formation of chromosomal aberrations: insights from studies with DNA repair-deficient cells. Cytogenet Genome Res (2004) 0.85
Microarray analysis in the HSV-1 latently infected mouse trigeminal ganglion. Cornea (2004) 0.84
Relationship between XPG codon 1104 polymorphism and risk of primary lung cancer. Carcinogenesis (2003) 0.84
Functional link between Myc and the Werner gene in tumorigenesis. Cell Cycle (2004) 0.82
The involvement of key DNA repair pathways in the formation of chromosome rearrangements in embryonic stem cells. DNA Repair (Amst) (2005) 0.81
Suppression of UV-induced apoptosis by the human DNA repair protein XPG. Cell Death Differ (2006) 0.81
Chromosomal doubling: the significance of polyploidization in the development of human tumors: possibly relevant findings on a lymphoma. Cancer Genet Cytogenet (2000) 0.76
Genome-wide association study identifies novel breast cancer susceptibility loci. Nature (2007) 29.23
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet (2007) 22.96
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet (2007) 21.18
Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst (2004) 19.00
Multiple loci identified in a genome-wide association study of prostate cancer. Nat Genet (2008) 17.65
Delivering affordable cancer care in high-income countries. Lancet Oncol (2011) 12.79
Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell (2009) 11.65
The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. JAMA (2013) 10.43
Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review. Cancer Epidemiol Biomarkers Prev (2005) 9.47
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat Genet (2009) 8.39
Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood (2005) 8.37
Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat Genet (2013) 8.24
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
A common coding variant in CASP8 is associated with breast cancer risk. Nat Genet (2007) 7.35
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. Nat Genet (2009) 7.30
Association between body-mass index and risk of death in more than 1 million Asians. N Engl J Med (2011) 6.89
A draft sequence for the genome of the domesticated silkworm (Bombyx mori). Science (2004) 6.62
The Shanghai Women's Health Study: rationale, study design, and baseline characteristics. Am J Epidemiol (2005) 6.44
WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res (2013) 6.17
Characterization of the human heart mitochondrial proteome. Nat Biotechnol (2003) 5.66
A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet (2013) 5.58
The Diesel Exhaust in Miners study: a nested case-control study of lung cancer and diesel exhaust. J Natl Cancer Inst (2012) 5.27
Association of low-level ozone and fine particles with respiratory symptoms in children with asthma. JAMA (2003) 5.19
Telomere dysfunction: a potential cancer predisposition factor. J Natl Cancer Inst (2003) 5.09
A SNP in a let-7 microRNA complementary site in the KRAS 3' untranslated region increases non-small cell lung cancer risk. Cancer Res (2008) 5.05
NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses. Lancet (2005) 5.01
Cutaneous melanoma attributable to sunbed use: systematic review and meta-analysis. BMJ (2012) 4.79
SNP500Cancer: a public resource for sequence validation, assay development, and frequency analysis for genetic variation in candidate genes. Nucleic Acids Res (2006) 4.63
A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation. PLoS Genet (2008) 4.57
Meta-analysis of risk factors for cutaneous melanoma: II. Sun exposure. Eur J Cancer (2005) 4.55
Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies. J Natl Cancer Inst (2010) 4.54
Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat Genet (2010) 4.51
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat Genet (2009) 4.38
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Hematotoxicity in workers exposed to low levels of benzene. Science (2004) 4.19
Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. Lancet Oncol (2006) 4.13
Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer. Gastroenterology (2009) 4.08
Cohort Profile: The China Health and Nutrition Survey--monitoring and understanding socio-economic and health change in China, 1989-2011. Int J Epidemiol (2009) 4.08
Genome-wide association study of circulating vitamin D levels. Hum Mol Genet (2010) 4.07
Improved identification of von Hippel-Lindau gene alterations in clear cell renal tumors. Clin Cancer Res (2008) 4.02
Critical role of prostate biopsy mortality in the number of years of life gained and lost within a prostate cancer screening programme. BJU Int (2012) 4.01
A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci. Nat Genet (2010) 3.93
Mutation of GATA3 in human breast tumors. Oncogene (2004) 3.92
Hospitalization, restricted activity, and the development of disability among older persons. JAMA (2004) 3.85
Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium. Blood (2008) 3.81
Genome-wide association studies identify four ER negative-specific breast cancer risk loci. Nat Genet (2013) 3.81
Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data. Proc Natl Acad Sci U S A (2011) 3.80
Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Res (2005) 3.78
International patterns and trends in thyroid cancer incidence, 1973-2002. Cancer Causes Control (2008) 3.72
Detectable clonal mosaicism and its relationship to aging and cancer. Nat Genet (2012) 3.69
Genomic DNA hypomethylation as a biomarker for bladder cancer susceptibility in the Spanish Bladder Cancer Study: a case-control study. Lancet Oncol (2008) 3.60
Alcohol poisoning is a main determinant of recent mortality trends in Russia: evidence from a detailed analysis of mortality statistics and autopsies. Int J Epidemiol (2008) 3.56
A shared susceptibility locus in PLCE1 at 10q23 for gastric adenocarcinoma and esophageal squamous cell carcinoma. Nat Genet (2010) 3.53
SNP500Cancer: a public resource for sequence validation and assay development for genetic variation in candidate genes. Nucleic Acids Res (2004) 3.47
Population substructure and control selection in genome-wide association studies. PLoS One (2008) 3.44
Lower urinary tract symptoms and male sexual dysfunction: the multinational survey of the aging male (MSAM-7). Eur Urol (2003) 3.31
Breast cancer. Lancet (2005) 3.27
'Environment' in cancer causation and etiological fraction: limitations and ambiguities. Carcinogenesis (2007) 3.20
Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet (2012) 3.20
Italian randomized trial among women with hysterectomy: tamoxifen and hormone-dependent breast cancer in high-risk women. J Natl Cancer Inst (2003) 3.20
Multiple human papillomavirus genotype infections in cervical cancer progression in the study to understand cervical cancer early endpoints and determinants. Int J Cancer (2009) 3.15
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study. Nat Genet (2011) 3.07
A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies. Nat Genet (2009) 3.06
Meta-analysis of risk factors for cutaneous melanoma: I. Common and atypical naevi. Eur J Cancer (2005) 3.02
Beyond odds ratios--communicating disease risk based on genetic profiles. Nat Rev Genet (2009) 3.01
Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One (2009) 3.00
Counterpoint: bias from population stratification is not a major threat to the validity of conclusions from epidemiological studies of common polymorphisms and cancer. Cancer Epidemiol Biomarkers Prev (2002) 2.99
Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. J Clin Invest (2011) 2.99