Published in Ai Zheng on August 01, 2002
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Apixaban versus warfarin in patients with atrial fibrillation. N Engl J Med (2011) 23.50
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Mapping the genetic architecture of gene expression in human liver. PLoS Biol (2008) 19.44
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A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature (2005) 5.50
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Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells. Nat Struct Mol Biol (2013) 4.04
Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase. Science (2003) 3.92
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The RickA protein of Rickettsia conorii activates the Arp2/3 complex. Nature (2004) 2.73
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Bacterial peptidoglycan triggers Candida albicans hyphal growth by directly activating the adenylyl cyclase Cyr1p. Cell Host Microbe (2008) 2.68
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Genome-wide genetic changes during modern breeding of maize. Nat Genet (2012) 2.60
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Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat Genet (2010) 2.41
Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis. Curr Biol (2002) 2.38
Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor. Genes Dev (2004) 2.35
The Arp2/3 complex is required for lamellipodia extension and directional fibroblast cell migration. J Cell Biol (2012) 2.34
ToxR regulon of Vibrio cholerae and its expression in vibrios shed by cholera patients. Proc Natl Acad Sci U S A (2003) 2.29
Mapping the genetic architecture of complex traits in experimental populations. Bioinformatics (2007) 2.27
The Ran GTPase mediates chromatin signaling to control cortical polarity during polar body extrusion in mouse oocytes. Dev Cell (2007) 2.27
Exercise prevents maternal high-fat diet-induced hypermethylation of the Pgc-1α gene and age-dependent metabolic dysfunction in the offspring. Diabetes (2014) 2.24
Prevalence of and risk factors for fatty liver in a general population of Shanghai, China. J Hepatol (2005) 2.21
Using allopurinol above the dose based on creatinine clearance is effective and safe in patients with chronic gout, including those with renal impairment. Arthritis Rheum (2011) 2.21
Giant-stroke, superelastic carbon nanotube aerogel muscles. Science (2009) 2.19
Highly coordinated gene regulation in mouse skeletal muscle regeneration. J Biol Chem (2002) 2.17
ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. J Clin Invest (2008) 2.16
Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. Blood (2010) 2.15
A paired-end sequencing strategy to map the complex landscape of transcription initiation. Nat Methods (2010) 2.14
Decoding a new neural machine interface for control of artificial limbs. J Neurophysiol (2007) 2.11
Detection of minor drug-resistant populations by parallel allele-specific sequencing. Nat Methods (2007) 2.09
Comprehensive analysis of microRNA expression patterns in renal biopsies of lupus nephritis patients. Rheumatol Int (2008) 2.09
Meta-analysis of effectiveness of first-generation drug-eluting stents versus coronary artery bypass grafting for unprotected left main coronary disease. Am J Cardiol (2012) 2.07
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Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver. Genome Res (2010) 2.06
Nuclear export and retention signals in the RS domain of SR proteins. Mol Cell Biol (2002) 2.04
Reduction in asthma-related emergency department visits after implementation of a smoke-free law. J Allergy Clin Immunol (2008) 2.02
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A (2011) 2.01
Elucidating the murine brain transcriptional network in a segregating mouse population to identify core functional modules for obesity and diabetes. J Neurochem (2006) 2.00
Pharmacokinetics of oral methotrexate in patients with rheumatoid arthritis. Arthritis Rheum (2008) 1.99
Bidirectional control of social hierarchy by synaptic efficacy in medial prefrontal cortex. Science (2011) 1.97
Mitochondrial translocation of cofilin is an early step in apoptosis induction. Nat Cell Biol (2003) 1.94
Focal atrial tachycardia originating from the non-coronary aortic sinus: electrophysiological characteristics and catheter ablation. J Am Coll Cardiol (2006) 1.88
Metabolism of bile salts in mice influences spore germination in Clostridium difficile. PLoS One (2010) 1.87
Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS One (2009) 1.87
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A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles. Mol Microbiol (2008) 1.83
MicroRNA-204/211 alters epithelial physiology. FASEB J (2010) 1.83
Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy. Nature (2012) 1.82
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Epigenetic signatures of autism: trimethylated H3K4 landscapes in prefrontal neurons. Arch Gen Psychiatry (2011) 1.81
A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing. Proc Natl Acad Sci U S A (2006) 1.78
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Cancer cell dependence on unsaturated fatty acids implicates stearoyl-CoA desaturase as a target for cancer therapy. Mol Cancer Res (2011) 1.76
Unusual variants of Alexander's disease. Ann Neurol (2005) 1.76
Dual modes of cdc42 recycling fine-tune polarized morphogenesis. Dev Cell (2009) 1.73
Dynamic maintenance of asymmetric meiotic spindle position through Arp2/3-complex-driven cytoplasmic streaming in mouse oocytes. Nat Cell Biol (2011) 1.73
PGC-1alpha plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle. Am J Physiol Cell Physiol (2009) 1.72
Forkhead transcription factor foxq1 promotes epithelial-mesenchymal transition and breast cancer metastasis. Cancer Res (2011) 1.71
Monitoring the safety of quadrivalent human papillomavirus vaccine: findings from the Vaccine Safety Datalink. Vaccine (2011) 1.70
Long-range polony haplotyping of individual human chromosome molecules. Nat Genet (2006) 1.69
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. Nat Genet (2010) 1.69
Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited. Mol Biol Cell (2011) 1.68
PML nuclear bodies and apoptosis. Oncogene (2004) 1.66