Published in BMJ on December 21, 2002
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses. Endocr Rev (2012) 6.12
Parachute use to prevent death and major trauma related to gravitational challenge: systematic review of randomised controlled trials. BMJ (2003) 4.69
Issues in the reporting of epidemiological studies: a survey of recent practice. BMJ (2004) 4.69
Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med (2007) 3.71
Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology? Hum Genet (2007) 3.13
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression. Int J Epidemiol (2015) 2.78
The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) Statement. PLoS Med (2015) 2.72
Mendelian randomization: genetic anchors for causal inference in epidemiological studies. Hum Mol Genet (2014) 2.58
Embodiment: a conceptual glossary for epidemiology. J Epidemiol Community Health (2005) 2.42
Believability of relative risks and odds ratios in abstracts: cross sectional study. BMJ (2006) 1.89
Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study. Eur Heart J (2008) 1.76
Why do those out of work because of sickness or disability have a high mortality risk? Evidence from a Scottish cohort. Eur J Public Health (2012) 1.42
Effects of promoting longer-term and exclusive breastfeeding on adiposity and insulin-like growth factor-I at age 11.5 years: a randomized trial. JAMA (2013) 1.37
Fertility and markers of male reproductive function in Inuit and European populations spanning large contrasts in blood levels of persistent organochlorines. Environ Health Perspect (2008) 1.13
Socioeconomic position and hormone replacement therapy use: explaining the discrepancy in evidence from observational and randomized controlled trials. Am J Public Health (2004) 1.10
Evaluating genetic counseling for family members of individuals with schizophrenia in the molecular age. Schizophr Bull (2012) 1.08
Sample size and power calculations in Mendelian randomization with a single instrumental variable and a binary outcome. Int J Epidemiol (2014) 1.07
A questionnaire to assess the relevance and credibility of observational studies to inform health care decision making: an ISPOR-AMCP-NPC Good Practice Task Force report. Value Health (2014) 1.05
Epigenome-wide Association Studies and the Interpretation of Disease -Omics. PLoS Genet (2016) 1.05
The three stages of building and testing mid-level theories in a realist RCT: a theoretical and methodological case-example. Trials (2015) 1.02
STRengthening analytical thinking for observational studies: the STRATOS initiative. Stat Med (2014) 1.01
Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies. Am J Clin Nutr (2016) 0.98
Confounding in publications of observational intervention studies. Eur J Epidemiol (2007) 0.96
Randomised by (your) god: robust inference from an observational study design. J Epidemiol Community Health (2006) 0.93
Realist complex intervention science: Applying realist principles across all phases of the Medical Research Council framework for developing and evaluating complex interventions. Evaluation (Lond) (2016) 0.92
Methods used to estimate the size of the owned cat and dog population: a systematic review. BMC Vet Res (2013) 0.90
Using Mendelian randomisation to infer causality in depression and anxiety research. Depress Anxiety (2013) 0.88
MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization. Sci Rep (2015) 0.86
Positive psychology in cancer care: a story line resistant to evidence. Ann Behav Med (2010) 0.85
Publication bias and the canonization of false facts. Elife (2016) 0.84
Use of fibrates and cancer risk: a systematic review and meta-analysis of 17 long-term randomized placebo-controlled trials. PLoS One (2012) 0.80
From stem cells to the law courts: DNA methylation, the forensic epigenome and the possibility of a biosocial archive. Int J Epidemiol (2015) 0.79
Commentary: prostate cancer is omnipresent, but should we screen for it? Int J Epidemiol (2007) 0.78
Why do we read many articles with bad statistics? : what does the new American Statistical Association's statement on p-values mean? Korean J Anesthesiol (2016) 0.78
Randomized controlled trials in environmental health research: unethical or underutilized? PLoS Med (2015) 0.77
Model-Free Estimation of Tuning Curves and Their Attentional Modulation, Based on Sparse and Noisy Data. PLoS One (2016) 0.77
A critical appraisal of epidemiological studies comes from basic knowledge: a reader's guide to assess potential for biases. World J Emerg Surg (2007) 0.76
Optimized design and analysis of preclinical intervention studies in vivo. Sci Rep (2016) 0.75
Insect transformation with piggyBac: getting the number of injections just right. Insect Mol Biol (2016) 0.75
Re: Association of polymorphism in cytochrome P450 2C9 with susceptibility to head and neck cancer and treatment outcome: Pragmatic use of Hardy-Weinberg equilibrium and statistical interaction analysis. Appl Transl Genom (2014) 0.75
Logical fallacies in animal model research. Behav Brain Funct (2017) 0.75
[The REporting of studies Conducted using Observational Routinely-collected health Data (RECORD) statement]. Z Evid Fortbild Qual Gesundhwes (2016) 0.75
Effect of NSAIDs on risk of Alzheimer's disease: confounding factors were not discussed. BMJ (2003) 0.75
Measuring the statistical validity of summary meta-analysis and meta-regression results for use in clinical practice. Stat Med (2017) 0.75
The effect of targeted treatment on people with patellofemoral pain: a pragmatic, randomised controlled feasibility study. BMC Musculoskelet Disord (2017) 0.75
The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. The Alpha-Tocopherol, Beta Carotene Cancer Prevention Study Group. N Engl J Med (1994) 16.96
'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol (2003) 16.71
MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet (2002) 7.41
Alcohol, tobacco and breast cancer--collaborative reanalysis of individual data from 53 epidemiological studies, including 58,515 women with breast cancer and 95,067 women without the disease. Br J Cancer (2002) 5.83
Can dietary beta-carotene materially reduce human cancer rates? Nature (1981) 4.43
Evidence from randomised trials on the long-term effects of hormone replacement therapy. Lancet (2002) 3.70
Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence. Prev Med (1991) 3.53
Psychological stress and cardiovascular disease: empirical demonstration of bias in a prospective observational study of Scottish men. BMJ (2002) 3.33
Carcinogenic and endocrine disrupting effects of cigarette smoke and risk of breast cancer. Lancet (2002) 2.79
Vitamin A and lung cancer. Nutr Rev (1990) 1.49
Postmenopausal estrogen use and heart disease. N Engl J Med (1986) 1.19
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science (2007) 37.88
Newly identified loci that influence lipid concentrations and risk of coronary artery disease. Nat Genet (2008) 25.83
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet (2008) 22.35
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet (2010) 17.89
'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol (2003) 16.71
Common variants near MC4R are associated with fat mass, weight and risk of obesity. Nat Genet (2008) 15.94
Priority actions for the non-communicable disease crisis. Lancet (2011) 15.18
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
European guidelines on cardiovascular disease prevention in clinical practice. Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice. Eur Heart J (2003) 8.51
Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials. Am J Med (2004) 8.07
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet (2008) 7.31
Mapping cis- and trans-regulatory effects across multiple tissues in twins. Nat Genet (2012) 6.97
Those confounded vitamins: what can we learn from the differences between observational versus randomised trial evidence? Lancet (2004) 6.37
European guidelines on cardiovascular disease prevention in clinical practice: full text. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur J Cardiovasc Prev Rehabil (2007) 6.10
Where is the evidence that animal research benefits humans? BMJ (2004) 5.99
Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet (2009) 5.81
Statins for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev (2013) 5.57
Reduced dietary salt for the prevention of cardiovascular disease: a meta-analysis of randomized controlled trials (Cochrane review). Am J Hypertens (2011) 5.54
C-reactive protein and its role in metabolic syndrome: mendelian randomisation study. Lancet (2005) 5.51
Effect of infant feeding on the risk of obesity across the life course: a quantitative review of published evidence. Pediatrics (2005) 5.47
Statins for the primary prevention of cardiovascular disease. Cochrane Database Syst Rev (2011) 5.30
Patterns of cis regulatory variation in diverse human populations. PLoS Genet (2012) 5.28
Mendelian randomization: prospects, potentials, and limitations. Int J Epidemiol (2004) 5.07
Complex interventions to improve physical function and maintain independent living in elderly people: a systematic review and meta-analysis. Lancet (2008) 4.97
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
Predictive accuracy of the Framingham coronary risk score in British men: prospective cohort study. BMJ (2003) 4.74
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways. Nat Genet (2012) 4.73
Exercise-based cardiac rehabilitation for coronary heart disease. Cochrane Database Syst Rev (2011) 4.72
Is income inequality a determinant of population health? Part 1. A systematic review. Milbank Q (2004) 4.51
Jumping the gun: the problematic discourse on socioeconomic status and cardiovascular health in India. Int J Epidemiol (2013) 4.47
The ORION statement: guidelines for transparent reporting of outbreak reports and intervention studies of nosocomial infection. Lancet Infect Dis (2007) 4.34
Improving the prevention and management of chronic disease in low-income and middle-income countries: a priority for primary health care. Lancet (2008) 4.32
Chronic diseases and injuries in India. Lancet (2011) 4.27
A life course approach to chronic disease epidemiology. Annu Rev Public Health (2005) 4.17
Raising the priority of preventing chronic diseases: a political process. Lancet (2010) 4.16
Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood. Circulation (2010) 4.12
Genome-wide association study identifies five loci associated with lung function. Nat Genet (2009) 4.10
Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med (2011) 3.94
Subgroup analyses in randomized trials: risks of subgroup-specific analyses; power and sample size for the interaction test. J Clin Epidemiol (2004) 3.93
Prevention of chronic diseases: a call to action. Lancet (2007) 3.87
Systematic review of long term effects of advice to reduce dietary salt in adults. BMJ (2002) 3.87
Use of accelerometers in a large field-based study of children: protocols, design issues, and effects on precision. J Phys Act Health (2008) 3.81
Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes (2008) 3.76
Genetic loci influencing kidney function and chronic kidney disease. Nat Genet (2010) 3.75
Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med (2007) 3.71
Systematic review of the influence of childhood socioeconomic circumstances on risk for cardiovascular disease in adulthood. Ann Epidemiol (2005) 3.70
NHS waiting lists and evidence of national or local failure: analysis of health service data. BMJ (2003) 3.60
Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels. J Clin Invest (2008) 3.51
(Mis)use of factor analysis in the study of insulin resistance syndrome. Am J Epidemiol (2004) 3.43
European guidelines on cardiovascular disease prevention in clinical practice: third joint task force of European and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of eight societies and by invited experts). Eur J Cardiovasc Prev Rehabil (2003) 3.43
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nat Genet (2010) 3.37
Lessons from the withdrawal of rofecoxib. BMJ (2004) 3.33
Poverty, child undernutrition and morbidity: new evidence from India. Bull World Health Organ (2005) 3.30
Secular trends in mortality by stroke subtype in the 20th century: a retrospective analysis. Lancet (2002) 3.29
A road map for efficient and reliable human genome epidemiology. Nat Genet (2006) 3.21
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
Objectively measured physical activity and fat mass in a large cohort of children. PLoS Med (2007) 3.14
Chronic diseases and calls to action. Int J Epidemiol (2008) 3.11
WHO study on Prevention of REcurrences of Myocardial Infarction and StrokE (WHO-PREMISE). Bull World Health Organ (2005) 3.09
Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet (2009) 3.09
Non-communicable diseases in low and middle-income countries: a priority or a distraction? Int J Epidemiol (2005) 3.06
Sleep duration and mortality: The effect of short or long sleep duration on cardiovascular and all-cause mortality in working men and women. Sleep Med (2002) 3.06
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat Genet (2011) 3.03
Genetic epidemiology and public health: hope, hype, and future prospects. Lancet (2005) 3.00
Admissions for myocardial infarction and World Cup football: database survey. BMJ (2002) 2.99
Evaluating the impact of population and high-risk strategies for the primary prevention of cardiovascular disease. Eur Heart J (2004) 2.91
How can we improve adherence to blood pressure-lowering medication in ambulatory care? Systematic review of randomized controlled trials. Arch Intern Med (2004) 2.89
Educational and organisational interventions used to improve the management of hypertension in primary care: a systematic review. Br J Gen Pract (2005) 2.83
Comparison of the associations of body mass index and measures of central adiposity and fat mass with coronary heart disease, diabetes, and all-cause mortality: a study using data from 4 UK cohorts. Am J Clin Nutr (2010) 2.82
Seventy-five genetic loci influencing the human red blood cell. Nature (2012) 2.77
Does the misreporting of adult body size depend upon an individual's height and weight? Methodological debate. Int J Epidemiol (2004) 2.73
Manufacturing epidemics: the role of global producers in increased consumption of unhealthy commodities including processed foods, alcohol, and tobacco. PLoS Med (2012) 2.71
Measuring socioeconomic position in health research. Br Med Bull (2007) 2.71
European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Fourth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts). Eur J Cardiovasc Prev Rehabil (2007) 2.70
Associations of circulating C-reactive protein and interleukin-6 with cancer risk: findings from two prospective cohorts and a meta-analysis. Cancer Causes Control (2008) 2.68
Association between falls in elderly women and chronic diseases and drug use: cross sectional study. BMJ (2003) 2.63
Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med (2008) 2.61
A genome-wide association meta-analysis identifies new childhood obesity loci. Nat Genet (2012) 2.60
Inequalities in premature mortality in Britain: observational study from 1921 to 2007. BMJ (2010) 2.59
Hypertensive disorders in pregnancy and subsequently measured cardiovascular risk factors. Obstet Gynecol (2009) 2.56
What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts. Int J Epidemiol (2011) 2.54
Best-practice interventions to reduce socioeconomic inequalities of coronary heart disease mortality in UK: a prospective occupational cohort study. Lancet (2008) 2.53
The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study. J Allergy Clin Immunol (2008) 2.53