Published in J Leukoc Biol on February 01, 2003
Accumulation of senescent cells in mitotic tissue of aging primates. Mech Ageing Dev (2006) 3.14
Telomere length measurement-caveats and a critical assessment of the available technologies and tools. Mutat Res (2011) 1.79
Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes. PLoS Genet (2012) 1.57
Hematopoietic stem-cell behavior in nonhuman primates. Blood (2007) 1.27
Passage-dependent changes in baboon endothelial cells--relevance to in vitro aging. DNA Cell Biol (2004) 1.02
Lifelong leukocyte telomere dynamics and survival in a free-living mammal. Aging Cell (2015) 0.84
Age-related declines and disease-associated variation in immune cell telomere length in a wild mammal. PLoS One (2014) 0.84
Assessment of telomere length, phenotype, and DNA content. Curr Protoc Cytom (2004) 0.76
No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model. Mol Ther (2013) 0.76
A Cross-Sectional Study of Ageing and Cardiovascular Function over the Baboon Lifespan. PLoS One (2016) 0.75
Assessment of Telomere Length, Phenotype, and DNA Content. Curr Protoc Cytom (2017) 0.75
Prediction of survival in follicular lymphoma based on molecular features of tumor-infiltrating immune cells. N Engl J Med (2004) 12.20
Telomerase mutations in families with idiopathic pulmonary fibrosis. N Engl J Med (2007) 8.23
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia. N Engl J Med (2005) 7.09
The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. N Engl J Med (2006) 6.90
Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates. J Clin Invest (2008) 6.15
The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis. Mol Cell Biol (2003) 5.38
Telomeres and aging. Physiol Rev (2008) 4.79
TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita. Am J Hum Genet (2008) 4.12
Flow cytometry and FISH to measure the average length of telomeres (flow FISH). Nat Protoc (2006) 4.00
High-dose methotrexate with or without whole brain radiotherapy for primary CNS lymphoma (G-PCNSL-SG-1): a phase 3, randomised, non-inferiority trial. Lancet Oncol (2010) 3.88
Short telomeres are a risk factor for idiopathic pulmonary fibrosis. Proc Natl Acad Sci U S A (2008) 3.86
Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita. Blood (2007) 3.86
Disruption of dog-1 in Caenorhabditis elegans triggers deletions upstream of guanine-rich DNA. Nat Genet (2002) 3.50
Telomerase Inhibitor Imetelstat in Patients with Essential Thrombocythemia. N Engl J Med (2015) 3.00
Regulation of murine telomere length by Rtel: an essential gene encoding a helicase-like protein. Cell (2004) 2.91
Immune activation in patients with irritable bowel syndrome. Gastroenterology (2007) 2.82
Late presentation of dyskeratosis congenita as apparently acquired aplastic anaemia due to mutations in telomerase RNA. Lancet (2003) 2.76
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome. Blood (2003) 2.73
Constitutional hypomorphic telomerase mutations in patients with acute myeloid leukemia. Proc Natl Acad Sci U S A (2009) 2.44
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. Proc Natl Acad Sci U S A (2005) 2.01
CD27 expression promotes long-term survival of functional effector-memory CD8+ cytotoxic T lymphocytes in HIV-infected patients. J Exp Med (2004) 1.92
DNA template strand sequencing of single-cells maps genomic rearrangements at high resolution. Nat Methods (2012) 1.85
Telomere length measurement-caveats and a critical assessment of the available technologies and tools. Mutat Res (2011) 1.79
Telomere length is associated with disease severity and declines with age in dyskeratosis congenita. Haematologica (2011) 1.71
Long-term safety and efficacy of sustained eculizumab treatment in patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol (2013) 1.68
Synchrony of telomere length among hematopoietic cells. Exp Hematol (2010) 1.63
Mutations in the SBDS gene in acquired aplastic anemia. Blood (2007) 1.62
Telomerase levels control the lifespan of human T lymphocytes. Blood (2003) 1.59
A spectrum of severe familial liver disorders associate with telomerase mutations. PLoS One (2009) 1.57
Functional characterization of natural telomerase mutations found in patients with hematologic disorders. Blood (2006) 1.57
Collapse of telomere homeostasis in hematopoietic cells caused by heterozygous mutations in telomerase genes. PLoS Genet (2012) 1.57
RECQL, a member of the RecQ family of DNA helicases, suppresses chromosomal instability. Mol Cell Biol (2006) 1.54
Detection of G-quadruplex DNA in mammalian cells. Nucleic Acids Res (2013) 1.53
Identification of sister chromatids by DNA template strand sequences. Nature (2009) 1.53
Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia-telangiectasia. Hum Mol Genet (2003) 1.48
Telomere length measurement by fluorescence in situ hybridization and flow cytometry: tips and pitfalls. Cytometry (2002) 1.43
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita. Blood (2005) 1.37
Telomere length measurements in leukocyte subsets by automated multicolor flow-FISH. Cytometry A (2003) 1.36
Estimating human hematopoietic stem cell kinetics using granulocyte telomere lengths. Exp Hematol (2004) 1.33
Functional characterization of telomerase RNA variants found in patients with hematologic disorders. Blood (2004) 1.33
Phase II study of central nervous system (CNS)-directed chemotherapy including high-dose chemotherapy with autologous stem cell transplantation for CNS relapse of aggressive lymphomas. Haematologica (2012) 1.30
Ancestral mutation in telomerase causes defects in repeat addition processivity and manifests as familial pulmonary fibrosis. PLoS Genet (2011) 1.29
Telomere length in subpopulations of human hematopoietic cells. Stem Cells (2003) 1.28
RTEL1 contributes to DNA replication and repair and telomere maintenance. Mol Biol Cell (2012) 1.28
Longitudinal data on telomere length in leukocytes from newborn baboons support a marked drop in stem cell turnover around 1 year of age. Aging Cell (2006) 1.28
Hematopoietic stem-cell behavior in nonhuman primates. Blood (2007) 1.27
RTEL1: an essential helicase for telomere maintenance and the regulation of homologous recombination. Nucleic Acids Res (2010) 1.27
Telomere length in human natural killer cell subsets. Ann N Y Acad Sci (2007) 1.25
Synergistic role of Ku80 and poly(ADP-ribose) polymerase in suppressing chromosomal aberrations and liver cancer formation. Cancer Res (2002) 1.20
Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. Aging Cell (2007) 1.20
Alemtuzumab induces enhanced apoptosis in vitro in B-cells from patients with chronic lymphocytic leukemia by antibody-dependent cellular cytotoxicity. Eur J Pharmacol (2005) 1.16
Telomere length is inherited with resetting of the telomere set-point. Proc Natl Acad Sci U S A (2010) 1.15
Stem cells: hype and reality. Hematology Am Soc Hematol Educ Program (2002) 1.14
Telomeres, telomerase, and hematopoietic stem cell biology. Arch Med Res (2004) 1.10
Telomere length in Hutchinson-Gilford progeria syndrome. Mech Ageing Dev (2009) 1.10
Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure. Blood Cells Mol Dis (2006) 1.09
Long-term efficacy of the complement inhibitor eculizumab in cold agglutinin disease. Blood (2009) 1.08
Telomere maintenance in human B lymphocytes. Br J Haematol (2002) 1.08
Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies. Ann N Y Acad Sci (2009) 1.05
Characterization of primitive hematopoietic cells from patients with dyskeratosis congenita. Blood (2008) 1.04
Telomere length measurements using fluorescence in situ hybridization and flow cytometry. Methods Cell Biol (2004) 1.00
Longitudinal studies of telomere length in feline blood cells: implications for hematopoietic stem cell turnover in vivo. Exp Hematol (2002) 0.99
Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria. N Engl J Med (2015) 0.97
Reduced telomere length variation in healthy oldest old. Mech Ageing Dev (2008) 0.97
Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress--implications for tissue and organismal aging. Mech Ageing Dev (2011) 0.95
Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA). Blood (2009) 0.95
Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT. Blood (2005) 0.94
How to count chromosomes in a cell: An overview of current and novel technologies. Bioessays (2015) 0.92
Telomere length and the expression of natural telomeric genes in human fibroblasts. Hum Mol Genet (2003) 0.92
Telomere shortening in hematopoietic stem cell transplantation: a potential mechanism for late graft failure? Biol Blood Marrow Transplant (2002) 0.90
High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans. Nucleic Acids Res (2006) 0.90
The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly. J Biol Chem (2012) 0.89
Functional characterization of multiple domains involved in the subcellular localization of the hematopoietic Pbx interacting protein (HPIP). Oncogene (2002) 0.89
Telomeres and prognosis in patients with chronic lymphocytic leukaemia. Int J Hematol (2011) 0.88
Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1+ effector memory phenotype. Cancer Immunol Immunother (2013) 0.88
Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans. Nucleic Acids Res (2004) 0.88
Normalization of previously shortened telomere length under treatment with imatinib argues against a preexisting telomere length deficit in normal hematopoietic stem cells from patients with chronic myeloid leukemia. Ann N Y Acad Sci (2003) 0.86
Prolonged self-renewal activity unmasks telomerase control of telomere homeostasis and function of mouse hematopoietic stem cells. Blood (2011) 0.85
Chromosome orientation fluorescence in situ hybridization to study sister chromatid segregation in vivo. Nat Protoc (2010) 0.84
Analysis of repetitive DNA in chromosomes by flow cytometry. Nat Methods (2011) 0.83
Eculizumab, a terminal complement inhibitor, improves anaemia in patients with paroxysmal nocturnal haemoglobinuria. Br J Haematol (2008) 0.83
Telomere length in peripheral blood granulocytes reflects response to treatment with imatinib in patients with chronic myeloid leukemia. Blood (2003) 0.83
Outcome of elderly patients with primary CNS lymphoma in the G-PCNSL-SG-1 trial. Neurology (2012) 0.83
Strand-seq: a unifying tool for studies of chromosome segregation. Semin Cell Dev Biol (2013) 0.82
Telomeres in hematopoietic stem cells. Ann N Y Acad Sci (2003) 0.81
Effect of TERT and ATM on gene expression profiles in human fibroblasts. Genes Chromosomes Cancer (2004) 0.80
Prognostic impact of intraocular involvement in primary CNS lymphoma: experience from the G-PCNSL-SG1 trial. Ann Hematol (2014) 0.78
Hepatitis-associated aplastic anemia presenting as a familial bone marrow failure syndrome. J Pediatr Hematol Oncol (2009) 0.78
Flow cytometry and immunoselection of human stem cells. Methods Mol Med (2002) 0.77
Telomere length in paroxysmal nocturnal hemoglobinuria correlates with clone size. Exp Hematol (2007) 0.76
Renal histopathology of a baboon model with type 2 diabetes. Toxicol Pathol (2012) 0.76
Hand-foot syndrome: common presentation in an uncommon situation. Eur J Haematol (2013) 0.76
CLLU1 expression distinguishes chronic lymphocytic leukemia from other mature B-cell neoplasms. Leuk Res (2012) 0.75
Amyloid tumour. Br J Haematol (2009) 0.75
Nodular lesions of the scalp and a mediastinal mass in T cell acute lymphoblastic leukemia. Int J Hematol (2010) 0.75
Acral ischemia as a presenting manifestation of essential thrombocythemia. Int J Hematol (2011) 0.75
Feature analysis and centromere segmentation of human chromosome images using an iterative fuzzy algorithm. IEEE Trans Biomed Eng (2002) 0.75