Published in J Cell Sci on June 03, 2003
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
Histone H3 Thr-3 phosphorylation by Haspin positions Aurora B at centromeres in mitosis. Science (2010) 3.13
Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference. Mol Biol Cell (2005) 3.04
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol (2012) 2.99
Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94
Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins. Curr Opin Cell Biol (2009) 2.61
Kinetochore localization of spindle checkpoint proteins: who controls whom? Mol Biol Cell (2004) 2.50
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly. Dev Cell (2007) 2.25
Shugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeres. Genes Dev (2007) 2.06
CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1. Mol Cell Biol (2005) 2.00
Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell (2006) 1.94
Essential role of survivin, an inhibitor of apoptosis protein, in T cell development, maturation, and homeostasis. J Exp Med (2003) 1.83
Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death. J Exp Med (2004) 1.80
Cell division and cell survival in the absence of survivin. Proc Natl Acad Sci U S A (2004) 1.79
New wirings in the survivin networks. Oncogene (2008) 1.76
Survivin study: an update of "what is the next wave"? J Cell Physiol (2006) 1.63
The spindle checkpoint: a quality control mechanism which ensures accurate chromosome segregation. Chromosome Res (2004) 1.60
Survivin modulates microtubule dynamics and nucleation throughout the cell cycle. Mol Biol Cell (2006) 1.57
Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. J Cell Biol (2008) 1.54
Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells. J Exp Med (2007) 1.52
BUB1 mediation of caspase-independent mitotic death determines cell fate. J Cell Biol (2007) 1.52
The human synMuv-like protein LIN-9 is required for transcription of G2/M genes and for entry into mitosis. EMBO J (2006) 1.51
Glc7/protein phosphatase 1 regulatory subunits can oppose the Ipl1/aurora protein kinase by redistributing Glc7. Mol Cell Biol (2006) 1.50
Threonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitro. Cell Cycle (2011) 1.48
Cell division: control of the chromosomal passenger complex in time and space. Chromosoma (2013) 1.34
Uncoupling the central spindle-associated function of the chromosomal passenger complex from its role at centromeres. Mol Biol Cell (2006) 1.33
Survivin as a preferential target for cancer therapy. Int J Mol Sci (2014) 1.28
Survivin 2alpha: a novel Survivin splice variant expressed in human malignancies. Mol Cancer (2005) 1.26
INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization. J Cell Biol (2009) 1.23
Error-prone mammalian female meiosis from silencing the spindle assembly checkpoint without normal interkinetochore tension. Proc Natl Acad Sci U S A (2012) 1.23
Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy. Mol Cancer (2009) 1.23
The chromosomal passenger complex controls spindle checkpoint function independent from its role in correcting microtubule kinetochore interactions. Mol Biol Cell (2007) 1.23
Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation. Mol Cell Biol (2005) 1.20
Kinetochores and disease: keeping microtubule dynamics in check! Curr Opin Cell Biol (2011) 1.19
Targeting aurora kinases as therapy in multiple myeloma. Blood (2007) 1.19
IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells. PLoS Pathog (2006) 1.17
The Nup107-160 nucleoporin complex promotes mitotic events via control of the localization state of the chromosome passenger complex. Mol Biol Cell (2009) 1.15
Contribution of hCAP-D2, a non-SMC subunit of condensin I, to chromosome and chromosomal protein dynamics during mitosis. Mol Cell Biol (2005) 1.15
Endothelial cells from humans and mice with polycystic kidney disease are characterized by polyploidy and chromosome segregation defects through survivin down-regulation. Hum Mol Genet (2010) 1.11
Phosphorylation at serine 331 is required for Aurora B activation. J Cell Biol (2011) 1.10
The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression. Mol Biol Cell (2010) 1.10
Role of survivin phosphorylation by aurora B in mitosis. Cell Cycle (2007) 1.07
A small C-terminal sequence of Aurora B is responsible for localization and function. Mol Biol Cell (2004) 1.07
Novel components of human mitotic chromosomes identified by proteomic analysis of the chromosome scaffold fraction. Chromosoma (2004) 1.06
Survivin-directed RNA interference cocktail is a potent suppressor of tumour growth in vivo. J Med Genet (2005) 1.05
DNA damage associated with mitosis and cytokinesis failure. Oncogene (2013) 1.04
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers. Mol Cancer (2009) 1.01
The chromosomal passenger complex and the spindle assembly checkpoint: kinetochore-microtubule error correction and beyond. Cell Div (2008) 0.99
High-content, high-throughput analysis of cell cycle perturbations induced by the HSP90 inhibitor XL888. PLoS One (2011) 0.97
Deletion of caveolin-1 protects hyperoxia-induced apoptosis via survivin-mediated pathways. Am J Physiol Lung Cell Mol Physiol (2009) 0.97
Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis. J Biol Chem (2010) 0.96
Survivin: potential role in diagnosis, prognosis and targeted therapy of gastric cancer. World J Gastroenterol (2007) 0.95
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres. Chromosoma (2008) 0.94
Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: a promising strategy to overcome drug resistance in cancer. Cancer Lett (2013) 0.91
Liaisons between survivin and Plk1 during cell division and cell death. J Biol Chem (2010) 0.91
A survivin-ran complex regulates spindle formation in tumor cells. Mol Cell Biol (2008) 0.91
CENP-V is required for centromere organization, chromosome alignment and cytokinesis. EMBO J (2008) 0.91
The Aurora B Kinase in Chromosome Bi-Orientation and Spindle Checkpoint Signaling. Front Oncol (2015) 0.91
Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP. Mol Cancer (2014) 0.90
Survivin-induced Aurora-B kinase activation: A mechanism by which APC mutations contribute to increased mitoses during colon cancer development. Am J Pathol (2010) 0.88
Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe. Cell Death Dis (2014) 0.88
Role of Survivin in cytokinesis revealed by a separation-of-function allele. Mol Biol Cell (2011) 0.88
Senescent cells in growing tumors: population dynamics and cancer stem cells. PLoS Comput Biol (2012) 0.87
Development of replication-competent adenovirus for bladder cancer by controlling adenovirus E1a and E4 gene expression with the survivin promoter. Oncotarget (2014) 0.87
Autoantibodies against the chromosomal passenger protein INCENP found in a patient with Graham Little-Piccardi-Lassueur syndrome. J Autoimmune Dis (2007) 0.86
Nuclear survivin expression is a positive prognostic factor in taxane-platinum-treated ovarian cancer patients. J Ovarian Res (2011) 0.85
Downregulation of survivin by RNAi inhibits growth of human gastric carcinoma cells. World J Gastroenterol (2007) 0.84
Upregulation of CENP-H in tongue cancer correlates with poor prognosis and progression. J Exp Clin Cancer Res (2009) 0.84
Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis. Blood (2006) 0.82
Regulation of mitosis and taxane response by Daxx and Rassf1. Oncogene (2011) 0.81
Survivin is essential for fertile egg production and female fertility in mice. Cell Death Dis (2014) 0.81
What Drosophila spermatocytes tell us about the mechanisms underlying cytokinesis. Cytoskeleton (Hoboken) (2012) 0.80
Death receptor-induced apoptosis reveals a novel interplay between the chromosomal passenger complex and CENP-C during interphase. Mol Biol Cell (2007) 0.80
Multifunctional Polymeric Micelles Co-loaded with Anti-Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer. Mol Cancer Ther (2015) 0.79
Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer. Cancer Cell Int (2014) 0.79
Survivin safeguards chromosome numbers and protects from aneuploidy independently from p53. Mol Cancer (2014) 0.79
EpCAM Aptamer-mediated Survivin Silencing Sensitized Cancer Stem Cells to Doxorubicin in a Breast Cancer Model. Theranostics (2015) 0.79
Quantitative analysis of survivin protein expression and its therapeutic depletion by an antisense oligonucleotide in human lung tumors. Mol Ther Nucleic Acids (2012) 0.78
The functional repertoire of survivin's tails. Cell Cycle (2015) 0.78
Evaluation of activity and combination strategies with the microtubule-targeting drug sagopilone in breast cancer cell lines. Front Oncol (2011) 0.77
An antimitotic and antivascular agent BPR0L075 overcomes multidrug resistance and induces mitotic catastrophe in paclitaxel-resistant ovarian cancer cells. PLoS One (2013) 0.77
Aurora-C Interactions with Survivin and INCENP Reveal Shared and Distinct Features Compared with Aurora-B Chromosome Passenger Protein Complex. PLoS One (2016) 0.76
Optimization and apoptosis induction by RNAi with UTMD technology in vitro. Oncol Lett (2012) 0.76
Use of DT40 conditional-knockout cell lines to study chromosomal passenger protein function. Biochem Soc Trans (2010) 0.76
A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles. Sci Rep (2016) 0.75
Mitotic activity of survivin is regulated by acetylation at K129. Cell Cycle (2015) 0.75
Evaluation of antitumor activity of survivin short interfering RNA delivered by lipid nanoparticles in colon cancer in vitro and in vivo. Oncol Lett (2017) 0.75
Baculoviral delivery of CRISPR/Cas9 facilitates efficient genome editing in human cells. PLoS One (2017) 0.75
Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol (2007) 6.83
The cellular geography of aurora kinases. Nat Rev Mol Cell Biol (2003) 6.40
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell (2003) 4.13
The dynamic kinetochore-microtubule interface. J Cell Sci (2004) 4.07
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Cell (2010) 3.26
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nat Genet (2007) 3.08
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol (2012) 2.99
Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94
Chk1 is required for spindle checkpoint function. Dev Cell (2007) 2.90
Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes. Dev Cell (2003) 2.62
Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins. Curr Opin Cell Biol (2009) 2.61
Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. EMBO J (2004) 2.60
Inactivation of a human kinetochore by specific targeting of chromatin modifiers. Dev Cell (2008) 2.50
A super-resolution map of the vertebrate kinetochore. Proc Natl Acad Sci U S A (2010) 2.36
Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics. Cell (2003) 2.20
Trashing the genome: the role of nucleases during apoptosis. Nat Rev Mol Cell Biol (2005) 2.19
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol (2006) 2.16
Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα. J Cell Biol (2012) 1.94
CENP-I is essential for centromere function in vertebrate cells. Dev Cell (2002) 1.94
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J (2004) 1.89
Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J (2002) 1.82
Condensin regulates the stiffness of vertebrate centromeres. Mol Biol Cell (2009) 1.81
MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity. J Cell Biol (2002) 1.81
INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila. Dev Cell (2006) 1.71
Condensin: Architect of mitotic chromosomes. Chromosome Res (2009) 1.67
Phosphorylation of survivin at threonine 34 inhibits its mitotic function and enhances its cytoprotective activity. Cell Cycle (2009) 1.62
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis. J Cell Sci (2002) 1.61
Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59
Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array. EMBO J (2002) 1.58
Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. J Cell Biol (2008) 1.54
Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair. Mol Cell (2006) 1.54
Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo. J Biol Chem (2003) 1.50
Threonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitro. Cell Cycle (2011) 1.48
Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit. Dev Cell (2011) 1.43
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly. EMBO J (2012) 1.41
Separating the anti-apoptotic and mitotic roles of survivin. J Biol Chem (2006) 1.40
Contrasting roles of condensin I and condensin II in mitotic chromosome formation. J Cell Sci (2012) 1.35
Specific downregulation of bcl-2 and xIAP by RNAi enhances the effects of chemotherapeutic agents in MCF-7 human breast cancer cells. Cancer Gene Ther (2004) 1.33
The chromosomal passenger complex activates Polo kinase at centromeres. PLoS Biol (2012) 1.33
Sgt1 is required for human kinetochore assembly. EMBO Rep (2004) 1.30
Chromosome engineering allows the efficient isolation of vertebrate neocentromeres. Dev Cell (2013) 1.30
Human artificial chromosome with a conditional centromere for gene delivery and gene expression. DNA Res (2010) 1.29
Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function. Mol Biol Cell (2006) 1.26
Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology. Expert Opin Drug Deliv (2014) 1.26
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains. J Cell Sci (2002) 1.25
INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization. J Cell Biol (2009) 1.23
Nuclear survivin has reduced stability and is not cytoprotective. J Biol Chem (2007) 1.23
Endopolyploidy in irradiated p53-deficient tumour cell lines: persistence of cell division activity in giant cells expressing Aurora-B kinase. Cell Biol Int (2008) 1.22
The chromosomal passenger complex: one for all and all for one. Cell (2007) 1.22
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci U S A (2011) 1.21
RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate. J Cell Sci (2003) 1.20
Efficiency of de novo centromere formation in human artificial chromosomes. Genomics (2002) 1.19
Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier. Mol Biol Cell (2009) 1.19
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate. Nucleic Acids Res (2002) 1.15
In vivo functional dissection of human inner kinetochore protein CENP-C. J Struct Biol (2002) 1.14
Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores. EMBO Rep (2004) 1.11
Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis. Development (2008) 1.10
Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis. Exp Cell Res (2007) 1.10
Reverse genetics of essential genes in tissue-culture cells: 'dead cells talking'. Trends Cell Biol (2002) 1.10
SUMOylation modulates the function of Aurora-B kinase. J Cell Sci (2010) 1.10
Molecular analysis of survivin isoforms: evidence that alternatively spliced variants do not play a role in mitosis. J Biol Chem (2005) 1.07
Mitotic chromosome formation and the condensin paradox. Exp Cell Res (2004) 1.07
A new generation of human artificial chromosomes for functional genomics and gene therapy. Cell Mol Life Sci (2012) 1.06
Novel components of human mitotic chromosomes identified by proteomic analysis of the chromosome scaffold fraction. Chromosoma (2004) 1.06
Molecular and genetic analysis of condensin function in vertebrate cells. Mol Biol Cell (2008) 1.06
Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res (2005) 1.05
Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function. J Cell Sci (2012) 1.03
Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes. Nat Commun (2013) 1.02
HACking the centromere chromatin code: insights from human artificial chromosomes. Chromosome Res (2012) 1.02
A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes. Proc Natl Acad Sci U S A (2008) 1.01
Involvement of centrosome amplification in radiation-induced mitotic catastrophe. Cell Cycle (2007) 1.01
Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere. ACS Synth Biol (2012) 0.99
Nuclear survivin abrogates multiple cell cycle checkpoints and enhances viral oncolysis. Cancer Res (2008) 0.99
Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis. J Cell Sci (2003) 0.99
Apoptosis-associated caspase activation assays. Methods (2008) 0.98
Gradient of increasing Aurora B kinase activity is required for cells to execute mitosis. J Biol Chem (2010) 0.96
Building mitotic chromosomes. Curr Opin Cell Biol (2010) 0.95
Polo-like kinase-activating kinases: Aurora A, Aurora B and what else? Cell Cycle (2012) 0.94
How do kinetochores CLASP dynamic microtubules? Cell Cycle (2003) 0.94
Super-resolution fluorescence microscopy as a tool to study the nanoscale organization of chromosomes. Curr Opin Chem Biol (2011) 0.93
Poorly differentiated carcinomas of the thyroid gland: a review of the clinicopathologic features of a series of 28 cases of a heterogeneous, clinically aggressive group of thyroid tumors. Int J Surg Pathol (2002) 0.92
A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells. BMC Cancer (2013) 0.92
Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells. J Biol Chem (2001) 0.91
Liaisons between survivin and Plk1 during cell division and cell death. J Biol Chem (2010) 0.91
CENP-V is required for centromere organization, chromosome alignment and cytokinesis. EMBO J (2008) 0.91
Caspase-7 gene disruption reveals an involvement of the enzyme during the early stages of apoptosis. J Biol Chem (2003) 0.89
p21 Promotes oncolytic adenoviral activity in ovarian cancer and is a potential biomarker. Mol Cancer (2010) 0.87
The polo-like kinase inhibitor BI 2536 exhibits potent activity against malignant plasma cells and represents a novel therapy in multiple myeloma. Exp Hematol (2010) 0.87
Genetic analysis of the short splice variant of the inhibitor of caspase-activated DNase (ICAD-S) in chicken DT40 cells. J Biol Chem (2007) 0.85
Repo-Man-PP1: a link between chromatin remodelling and nuclear envelope reassembly. Nucleus (2012) 0.85