Published in J Biol Chem on October 18, 2010
A chemical biology strategy to analyze rheostat-like protein kinase-dependent regulation. Chem Biol (2013) 1.50
Cell division: control of the chromosomal passenger complex in time and space. Chromosoma (2013) 1.34
A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. J Cell Biol (2012) 1.27
Phosphorylation at serine 331 is required for Aurora B activation. J Cell Biol (2011) 1.10
Polo-like kinase-1 triggers histone phosphorylation by Haspin in mitosis. EMBO Rep (2014) 1.00
Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes. PLoS Genet (2014) 0.95
High-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis. Dev Cell (2014) 0.94
The Renaissance or the cuckoo clock. Philos Trans R Soc Lond B Biol Sci (2011) 0.85
Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase. Biol Open (2013) 0.82
Overexpression of hnRNPC2 induces multinucleation by repression of Aurora B in hepatocellular carcinoma cells. Oncol Lett (2013) 0.78
Targeting the INCENP IN-box-Aurora B interaction to inhibit CPC activity in vivo. Open Biol (2014) 0.78
Large tumor suppressors 1 and 2 regulate Aurora-B through phosphorylation of INCENP to ensure completion of cytokinesis. Heliyon (2016) 0.76
Bistability of a coupled Aurora B kinase-phosphatase system in cell division. Elife (2016) 0.76
A quantitative atlas of mitotic phosphorylation. Proc Natl Acad Sci U S A (2008) 10.07
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores. J Cell Biol (2003) 9.27
Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol (2007) 6.83
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. Mol Cell (2008) 5.38
Exploring the functional interactions between Aurora B, INCENP, and survivin in mitosis. Mol Biol Cell (2003) 4.28
The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis. J Cell Biol (1987) 4.05
Structure of a Survivin-Borealin-INCENP core complex reveals how chromosomal passengers travel together. Cell (2007) 3.98
Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis. Dev Cell (2010) 3.72
Phosphoproteome analysis of the human mitotic spindle. Proc Natl Acad Sci U S A (2006) 3.56
INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr Biol (2000) 3.55
Aurora B phosphorylates spatially distinct targets to differentially regulate the kinetochore-microtubule interface. Mol Cell (2010) 3.44
Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol Cell (2005) 3.14
Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94
Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins. Curr Opin Cell Biol (2009) 2.61
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation. Mol Biol Cell (2002) 2.56
Chromosomal passengers: toward an integrated view of mitosis. Chromosoma (1991) 2.54
Chromatin-associated protein phosphatase 1 regulates aurora-B and histone H3 phosphorylation. J Biol Chem (2001) 2.54
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci (2003) 2.48
Phosphorylation of the carboxyl terminus of inner centromere protein (INCENP) by the Aurora B Kinase stimulates Aurora B kinase activity. J Biol Chem (2002) 2.40
Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol (2006) 2.16
Force and length in the mitotic spindle. Curr Biol (2009) 2.11
Centromere targeting of the chromosomal passenger complex requires a ternary subcomplex of Borealin, Survivin, and the N-terminal domain of INCENP. Mol Biol Cell (2006) 1.94
Survivin mediates targeting of the chromosomal passenger complex to the centromere and midbody. EMBO Rep (2006) 1.82
Sli15(INCENP) dephosphorylation prevents mitotic checkpoint reengagement due to loss of tension at anaphase onset. Curr Biol (2010) 1.82
Cohesin cleavage and Cdk inhibition trigger formation of daughter nuclei. Nat Cell Biol (2010) 1.74
Relocation of the chromosomal passenger complex prevents mitotic checkpoint engagement at anaphase. Curr Biol (2010) 1.72
Model of chromosome motility in Drosophila embryos: adaptation of a general mechanism for rapid mitosis. Biophys J (2006) 1.57
INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization. J Cell Biol (2009) 1.23
A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes. Proc Natl Acad Sci U S A (2008) 1.01
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres. Chromosoma (2008) 0.94
Chromosomal passengers: conducting cell division. Nat Rev Mol Cell Biol (2007) 6.83
The cellular geography of aurora kinases. Nat Rev Mol Cell Biol (2003) 6.40
Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell (2003) 4.13
The dynamic kinetochore-microtubule interface. J Cell Sci (2004) 4.07
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle. J Cell Biol (2004) 3.49
The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. Cell (2010) 3.26
Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling. Nat Genet (2007) 3.08
The chromosomal passenger complex (CPC): from easy rider to the godfather of mitosis. Nat Rev Mol Cell Biol (2012) 2.99
Chromosomal passengers: the four-dimensional regulation of mitotic events. Chromosoma (2004) 2.94
Chk1 is required for spindle checkpoint function. Dev Cell (2007) 2.90
Condensin is required for nonhistone protein assembly and structural integrity of vertebrate mitotic chromosomes. Dev Cell (2003) 2.62
Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins. Curr Opin Cell Biol (2009) 2.61
Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. EMBO J (2004) 2.60
Inactivation of a human kinetochore by specific targeting of chromatin modifiers. Dev Cell (2008) 2.50
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J Cell Sci (2003) 2.48
A super-resolution map of the vertebrate kinetochore. Proc Natl Acad Sci U S A (2010) 2.36
Human CLASP1 is an outer kinetochore component that regulates spindle microtubule dynamics. Cell (2003) 2.20
Trashing the genome: the role of nucleases during apoptosis. Nat Rev Mol Cell Biol (2005) 2.19
Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore. EMBO J (2010) 2.17
Condensin and Repo-Man-PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat Cell Biol (2006) 2.16
CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1. Mol Cell Biol (2005) 2.00
Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα. J Cell Biol (2012) 1.94
CENP-I is essential for centromere function in vertebrate cells. Dev Cell (2002) 1.94
Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J (2004) 1.89
Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. EMBO J (2002) 1.82
Condensin regulates the stiffness of vertebrate centromeres. Mol Biol Cell (2009) 1.81
MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity. J Cell Biol (2002) 1.81
INCENP and Aurora B promote meiotic sister chromatid cohesion through localization of the Shugoshin MEI-S332 in Drosophila. Dev Cell (2006) 1.71
Condensin: Architect of mitotic chromosomes. Chromosome Res (2009) 1.67
Kinetochore localisation of the DNA damage response component 53BP1 during mitosis. J Cell Sci (2002) 1.61
Aurora-C kinase is a novel chromosomal passenger protein that can complement Aurora-B kinase function in mitotic cells. Cell Motil Cytoskeleton (2004) 1.59
Co-localization of centromere activity, proteins and topoisomerase II within a subdomain of the major human X alpha-satellite array. EMBO J (2002) 1.58
Deconstructing Survivin: comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. J Cell Biol (2008) 1.54
Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-strand break repair. Mol Cell (2006) 1.54
Aurora-B phosphorylation in vitro identifies a residue of survivin that is essential for its localization and binding to inner centromere protein (INCENP) in vivo. J Biol Chem (2003) 1.50
Vertebrate cells genetically deficient for Cdc14A or Cdc14B retain DNA damage checkpoint proficiency but are impaired in DNA repair. J Cell Biol (2010) 1.44
Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit. Dev Cell (2011) 1.43
Breaking the HAC Barrier: histone H3K9 acetyl/methyl balance regulates CENP-A assembly. EMBO J (2012) 1.41
Contrasting roles of condensin I and condensin II in mitotic chromosome formation. J Cell Sci (2012) 1.35
The chromosomal passenger complex activates Polo kinase at centromeres. PLoS Biol (2012) 1.33
Sgt1 is required for human kinetochore assembly. EMBO Rep (2004) 1.30
Chromosome engineering allows the efficient isolation of vertebrate neocentromeres. Dev Cell (2013) 1.30
Human artificial chromosome with a conditional centromere for gene delivery and gene expression. DNA Res (2010) 1.29
Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function. Mol Biol Cell (2006) 1.26
Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology. Expert Opin Drug Deliv (2014) 1.26
CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains. J Cell Sci (2002) 1.25
INCENP-aurora B interactions modulate kinase activity and chromosome passenger complex localization. J Cell Biol (2009) 1.23
The chromosomal passenger complex: one for all and all for one. Cell (2007) 1.22
Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells. Proc Natl Acad Sci U S A (2011) 1.21
RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate. J Cell Sci (2003) 1.20
Efficiency of de novo centromere formation in human artificial chromosomes. Genomics (2002) 1.19
Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier. Mol Biol Cell (2009) 1.19
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate. Nucleic Acids Res (2002) 1.15
In vivo functional dissection of human inner kinetochore protein CENP-C. J Struct Biol (2002) 1.14
Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores. EMBO Rep (2004) 1.11
Dual roles of Incenp crucial to the assembly of the acentrosomal metaphase spindle in female meiosis. Development (2008) 1.10
Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis. Exp Cell Res (2007) 1.10
Reverse genetics of essential genes in tissue-culture cells: 'dead cells talking'. Trends Cell Biol (2002) 1.10
SUMOylation modulates the function of Aurora-B kinase. J Cell Sci (2010) 1.10
Mitotic chromosome formation and the condensin paradox. Exp Cell Res (2004) 1.07
A new generation of human artificial chromosomes for functional genomics and gene therapy. Cell Mol Life Sci (2012) 1.06
Molecular and genetic analysis of condensin function in vertebrate cells. Mol Biol Cell (2008) 1.06
Novel components of human mitotic chromosomes identified by proteomic analysis of the chromosome scaffold fraction. Chromosoma (2004) 1.06
Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res (2005) 1.05
Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function. J Cell Sci (2012) 1.03
Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes. Nat Commun (2013) 1.02
HACking the centromere chromatin code: insights from human artificial chromosomes. Chromosome Res (2012) 1.02
A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes. Proc Natl Acad Sci U S A (2008) 1.01
Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere. ACS Synth Biol (2012) 0.99
Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis. J Cell Sci (2003) 0.99
Apoptosis-associated caspase activation assays. Methods (2008) 0.98
Building mitotic chromosomes. Curr Opin Cell Biol (2010) 0.95
How do kinetochores CLASP dynamic microtubules? Cell Cycle (2003) 0.94
Super-resolution fluorescence microscopy as a tool to study the nanoscale organization of chromosomes. Curr Opin Chem Biol (2011) 0.93
A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells. BMC Cancer (2013) 0.92
Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells. J Biol Chem (2001) 0.91
CENP-V is required for centromere organization, chromosome alignment and cytokinesis. EMBO J (2008) 0.91