Published in J Am Soc Nephrol on May 10, 2006
The reno-vascular A2B adenosine receptor protects the kidney from ischemia. PLoS Med (2008) 2.43
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis. J Clin Immunol (2008) 1.42
Human mannose-binding lectin inhibitor prevents Shiga toxin-induced renal injury. Kidney Int (2016) 1.39
Association of C4d deposition with clinical outcomes in IgA nephropathy. Clin J Am Soc Nephrol (2014) 1.28
Pathogenesis of Henoch-Schönlein purpura nephritis. Pediatr Nephrol (2009) 1.21
Immunopathogenesis of IgAN. Semin Immunopathol (2007) 1.16
Human L-ficolin (ficolin-2) and its clinical significance. J Biomed Biotechnol (2012) 1.12
Glomerular and tubular C4d depositions in IgA nephropathy: relations with histopathology and with albuminuria. Int J Clin Exp Pathol (2013) 1.11
Eculizumab treatment for rescue of renal function in IgA nephropathy. Pediatr Nephrol (2014) 1.09
Transglutaminase is essential for IgA nephropathy development acting through IgA receptors. J Exp Med (2012) 1.08
Decreased circulating C3 levels and mesangial C3 deposition predict renal outcome in patients with IgA nephropathy. PLoS One (2012) 1.08
Excretion of complement proteins and its activation marker C5b-9 in IgA nephropathy in relation to renal function. BMC Nephrol (2011) 1.08
New developments in the genetics, pathogenesis, and therapy of IgA nephropathy. Kidney Int (2015) 1.04
Differential deposition of C4d and MBL in glomeruli of patients with ANCA-negative pauci-immune crescentic glomerulonephritis. J Clin Immunol (2009) 1.03
Genetic evidence of functional ficolin-2 haplotype as susceptibility factor in cutaneous leishmaniasis. PLoS One (2012) 1.02
Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study. Biochemistry (2010) 1.02
Complement in glomerular injury. Semin Immunopathol (2007) 0.99
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Determination of severity of murine IgA nephropathy by glomerular complement activation by aberrantly glycosylated IgA and immune complexes. Am J Pathol (2012) 0.96
New insights into the pathogenesis of IgA nephropathy. Semin Immunopathol (2014) 0.96
Biomarkers in IgA nephropathy: relationship to pathogenetic hits. Expert Opin Med Diagn (2013) 0.96
Urinary prognostic biomarkers and classification of IgA nephropathy by high resolution mass spectrometry coupled with liquid chromatography. PLoS One (2013) 0.93
The role of complement in membranous nephropathy. Semin Nephrol (2013) 0.90
Treatment of IgA nephropathy and Henoch-Schönlein nephritis. Nat Rev Nephrol (2013) 0.90
Fluorochrome-linked immunoassay for functional analysis of the mannose binding lectin complement pathway to the level of C3 cleavage. J Immunol Methods (2007) 0.89
Haematuria as a risk factor for chronic kidney disease progression in glomerular diseases: A review. Pediatr Nephrol (2015) 0.87
The alternative pathway of complement activation may be involved in the renal damage of human anti-glomerular basement membrane disease. PLoS One (2014) 0.87
Henoch-Schönlein purpura nephritis. Pediatr Nephrol (2014) 0.86
Urinary mannose-binding lectin is a biomarker for predicting the progression of immunoglobulin (Ig)A nephropathy. Clin Exp Immunol (2012) 0.86
Role of complement in IgA nephropathy. J Nephrol (2015) 0.85
Association of glomerular C4d deposition with various demographic data in IgA nephropathy patients; a preliminary study. J Nephropathol (2015) 0.84
The combined role of galactose-deficient IgA1 and streptococcal IgA-binding M Protein in inducing IL-6 and C3 secretion from human mesangial cells: implications for IgA nephropathy. J Immunol (2014) 0.83
Circulating ficolin-2 and ficolin-3 in normal pregnancy and pre-eclampsia. Clin Exp Immunol (2012) 0.83
The Origin and Activities of IgA1-Containing Immune Complexes in IgA Nephropathy. Front Immunol (2016) 0.83
Pathogenetic and therapeutic approaches to IgA nephropathy using a spontaneous animal model, the ddY mouse. Clin Exp Nephrol (2010) 0.82
Combined C4d and CD3 immunostaining predicts immunoglobulin (Ig)A nephropathy progression. Clin Exp Immunol (2015) 0.82
C3a, C5a renal expression and their receptors are correlated to severity of IgA nephropathy. J Clin Immunol (2013) 0.80
Pathological scenario with the mannose-binding lectin in patients with IgA nephropathy. J Biomed Biotechnol (2012) 0.79
Relationship between serum IgA/C3 ratio and severity of histological lesions using the Oxford classification in children with IgA nephropathy. Pediatr Nephrol (2014) 0.79
Prognostic value of glomerular C4d staining in patients with IgA nephritis. Int J Clin Exp Pathol (2014) 0.79
FCGR2B and FCRLB gene polymorphisms associated with IgA nephropathy. PLoS One (2013) 0.79
Be alert to tuberculosis-mediated glomerulonephritis: a retrospective study. Eur J Clin Microbiol Infect Dis (2011) 0.78
Role of genetic polymorphisms in factor H and MBL genes in Tunisian patients with immunoglobulin A nephropathy. Int J Nephrol Renovasc Dis (2010) 0.78
Mesangial C4d deposition may predict progression of kidney disease in pediatric patients with IgA nephropathy. Pediatr Nephrol (2017) 0.78
Secretory immunoglobulin A (IgA) responses in IgA nephropathy patients after mucosal immunization, as part of a polymeric IgA response. Clin Exp Immunol (2008) 0.77
Underweight Is an Independent Risk Factor for Renal Function Deterioration in Patients with IgA Nephropathy. PLoS One (2016) 0.77
IgA nephropathy associated with a novel N-terminal mutation in factor H. Eur J Pediatr (2010) 0.77
The Genetics of IgA Nephropathy: An Overview from Western Countries. Kidney Dis (Basel) (2015) 0.76
Disruption of Smad4 expression in T cells leads to IgA nephropathy-like manifestations. PLoS One (2013) 0.76
Update on immunoglobulin A nephropathy, Part I: Pathophysiology. World J Nephrol (2015) 0.76
Glomerular mannose-binding lectin deposition is a useful prognostic predictor in immunoglobulin A nephropathy. Clin Exp Immunol (2013) 0.76
Oxford classification of IgA nephropathy and C4d deposition; correlation and its implication. J Nephropharmacol (2015) 0.75
The Expression Profile of Complement Components in Podocytes. Int J Mol Sci (2016) 0.75
Novel biomarkers in glomerular disease. Adv Chronic Kidney Dis (2014) 0.75
Optimizing the translational value of animal models of glomerulonephritis: insights from recent murine prototypes. Am J Physiol Renal Physiol (2016) 0.75
Implication of urinary complement factor H in the progression of immunoglobulin A nephropathy. PLoS One (2015) 0.75
Identification of mannose-binding lectin as a mechanism in progressive immunoglobulin A nephropathy. Int J Clin Exp Pathol (2015) 0.75
The solution structures of native and patient monomeric human IgA1 reveal asymmetric extended structures: implications for function and IgAN disease. Biochem J (2015) 0.75
Therapeutic regulation of complement in patients with renal disease - where is the promise? Clin Nephrol (2012) 0.75
IgA Nephropathy. Clin J Am Soc Nephrol (2017) 0.75
Decreased Serum C3 Levels in Immunoglobulin A (IgA) Nephropathy with Chronic Kidney Disease: A Propensity Score Matching Study. Med Sci Monit (2017) 0.75
Serum C3 and Renal Outcome in Patients with Primary Focal Segmental Glomerulosclerosis. Sci Rep (2017) 0.75
Inflammation in IgA nephropathy. Pediatr Nephrol (2017) 0.75
Complement Recognition Pathways in Renal Transplantation. J Am Soc Nephrol (2017) 0.75
Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy. Kidney Int (2017) 0.75
Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy. Clin Proteomics (2017) 0.75
Complement C5-inhibiting therapy for the thrombotic microangiopathies: accumulating evidence, but not a panacea. Clin Kidney J (2017) 0.75
Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis. Nat Med (2011) 6.35
Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest (2004) 4.65
Structures of complement component C3 provide insights into the function and evolution of immunity. Nature (2005) 4.01
Rituximab targets podocytes in recurrent focal segmental glomerulosclerosis. Sci Transl Med (2011) 3.19
Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases. Nat Immunol (2005) 2.82
The lectin-complement pathway--its role in innate immunity and evolution. Immunol Rev (2004) 2.73
Loss of the tumor suppressor Vhlh leads to upregulation of Cxcr4 and rapidly progressive glomerulonephritis in mice. Nat Med (2006) 2.65
The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility. J Immunol (2011) 2.44
Mannose binding lectin gene polymorphisms confer a major risk for severe infections after liver transplantation. Gastroenterology (2005) 2.30
Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation. Hepatology (2010) 2.25
Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. J Immunol (2003) 2.23
Extracellular adenosine production by ecto-5'-nucleotidase protects during murine hepatic ischemic preconditioning. Gastroenterology (2008) 2.18
Allergy is a protective factor against age-related macular degeneration. Invest Ophthalmol Vis Sci (2014) 2.09
Pros and cons for C4d as a biomarker. Kidney Int (2012) 2.03
Gastrointestinal ischemia-reperfusion injury is lectin complement pathway dependent without involving C1q. J Immunol (2005) 2.02
Defining cell-type specificity at the transcriptional level in human disease. Genome Res (2013) 1.96
Mannose-binding lectin is a regulator of inflammation that accompanies myocardial ischemia and reperfusion injury. J Immunol (2005) 1.89
Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo. Blood (2008) 1.72
L-ficolin is a pattern recognition molecule specific for acetyl groups. J Biol Chem (2004) 1.70
L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement. J Immunol (2004) 1.70
Complement induction in spinal cord microglia results in anaphylatoxin C5a-mediated pain hypersensitivity. J Neurosci (2007) 1.70
Mannan-binding lectin activates C3 and the alternative complement pathway without involvement of C2. J Clin Invest (2006) 1.69
Autologous bone marrow-derived mesenchymal stromal cells for the treatment of allograft rejection after renal transplantation: results of a phase I study. Stem Cells Transl Med (2013) 1.68
Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems. J Biol Chem (2003) 1.68
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q. Eur J Immunol (2003) 1.67
Association of soluble CD89 levels with disease progression but not susceptibility in IgA nephropathy. Kidney Int (2010) 1.66
Mannose-binding lectin engagement with late apoptotic and necrotic cells. Eur J Immunol (2003) 1.66
The complement system in systemic autoimmune disease. J Autoimmun (2009) 1.64
Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells. J Immunol (2004) 1.64
Effect of capsulation of opportunistic pathogenic bacteria on binding of the pattern recognition molecules mannan-binding lectin, L-ficolin, and H-ficolin. Infect Immun (2005) 1.64
Role of extracellular nucleotide phosphohydrolysis in intestinal ischemia-reperfusion injury. FASEB J (2008) 1.63
Complement drives Th17 cell differentiation and triggers autoimmune arthritis. J Exp Med (2010) 1.62
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury. Proc Natl Acad Sci U S A (2011) 1.58
Structural insights into the innate immune recognition specificities of L- and H-ficolins. EMBO J (2007) 1.53
IL-10-producing macrophages preferentially clear early apoptotic cells. Blood (2006) 1.53
Direct binding of C1q to apoptotic cells and cell blebs induces complement activation. Eur J Immunol (2002) 1.52
Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D. J Exp Med (2009) 1.51
Mannose-binding lectin (MBL)-associated serine protease (MASP)-1 contributes to activation of the lectin complement pathway. J Immunol (2008) 1.50
Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2. Hum Mol Genet (2005) 1.50
Human M-ficolin is a secretory protein that activates the lectin complement pathway. J Immunol (2005) 1.49
Functional characterization of the lectin pathway of complement in human serum. Mol Immunol (2003) 1.48
Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species. Proc Natl Acad Sci U S A (2010) 1.47
Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation. J Immunol (2008) 1.44
The detrimental effects of IFN-α on vasculogenesis in lupus are mediated by repression of IL-1 pathways: potential role in atherogenesis and renal vascular rarefaction. J Immunol (2010) 1.42
Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity. Blood (2005) 1.41
Inflammation in amyotrophic lateral sclerosis spinal cord and brain is mediated by activated macrophages, mast cells and T cells. Amyotroph Lateral Scler Other Motor Neuron Disord (2004) 1.35
Role of the alternative pathway in the early complement activation following major trauma. Shock (2007) 1.35
Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation. Biochemistry (2006) 1.32
Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes. J Clin Invest (2004) 1.31
Mannose-binding lectin binds IgM to activate the lectin complement pathway in vitro and in vivo. Immunobiology (2006) 1.30
Neutrophil-derived glutamate regulates vascular endothelial barrier function. J Biol Chem (2002) 1.30
A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet (2013) 1.29
Human mannose-binding lectin and L-ficolin function as specific pattern recognition proteins in the lectin activation pathway of complement. J Biol Chem (2004) 1.29
The role of ficolins in innate immunity. Immunobiology (2002) 1.29
The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection. PLoS Pathog (2012) 1.28
Hydrogen sulfide therapy attenuates the inflammatory response in a porcine model of myocardial ischemia/reperfusion injury. J Thorac Cardiovasc Surg (2009) 1.27
Factor B structure provides insights into activation of the central protease of the complement system. Nat Struct Mol Biol (2007) 1.27
Glomerular podocytes contain neuron-like functional synaptic vesicles. FASEB J (2006) 1.27
Specific binding of L-ficolin and H-ficolin to apoptotic cells leads to complement activation. Immunobiology (2005) 1.26
Chronic renal allograft rejection: pathophysiologic considerations. Kidney Int (2005) 1.26
Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood (2002) 1.26
CD20-positive infiltrates in human membranous glomerulonephritis. J Nephrol (2005) 1.26
Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease. J Clin Invest (2012) 1.25
The death ligand TRAIL in diabetic nephropathy. J Am Soc Nephrol (2008) 1.25
Myeloperoxidase is critically involved in the induction of organ damage after renal ischemia reperfusion. Am J Pathol (2007) 1.24
Myocardial ischemia and reperfusion injury is dependent on both IgM and mannose-binding lectin. Am J Physiol Heart Circ Physiol (2009) 1.22
The MIF receptor CD74 in diabetic podocyte injury. J Am Soc Nephrol (2008) 1.22
Complement activation by (auto-) antibodies. Mol Immunol (2011) 1.22
Cannabinoid receptor 1 blockade ameliorates albuminuria in experimental diabetic nephropathy. Diabetes (2010) 1.21
Murine model of gastrointestinal ischemia associated with complement-dependent injury. J Appl Physiol (1985) (2002) 1.21
The role of mannose-binding lectin-associated serine protease-3 in activation of the alternative complement pathway. J Immunol (2011) 1.20
Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration. Ophthalmology (2011) 1.20
Maturation of dendritic cells abrogates C1q production in vivo and in vitro. Blood (2004) 1.20
The membrane attack complex of complement induces caspase activation and apoptosis. Eur J Immunol (2002) 1.20
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins. J Immunol (2005) 1.19
Role of ficolin in innate immunity and its molecular basis. Immunobiology (2007) 1.19
Activation of the lectin complement pathway by H-ficolin (Hakata antigen). J Immunol (2002) 1.19
Recognition and clearance of apoptotic cells: a role for complement and pentraxins. Trends Immunol (2003) 1.17
Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF and rapamycin. Transplantation (2008) 1.17