Published in J Autoimmun on December 11, 2009
Complement in immune and inflammatory disorders: pathophysiological mechanisms. J Immunol (2013) 2.10
Pros and cons for C4d as a biomarker. Kidney Int (2012) 2.03
Epidemiology of environmental exposures and human autoimmune diseases: findings from a National Institute of Environmental Health Sciences Expert Panel Workshop. J Autoimmun (2012) 1.43
C5a receptor (CD88) blockade protects against MPO-ANCA GN. J Am Soc Nephrol (2013) 1.38
Complement--tapping into new sites and effector systems. Nat Rev Immunol (2014) 1.30
The immune system in children with malnutrition--a systematic review. PLoS One (2014) 1.22
Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency. Mol Immunol (2010) 1.18
Glomerular and tubular C4d depositions in IgA nephropathy: relations with histopathology and with albuminuria. Int J Clin Exp Pathol (2013) 1.11
Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy. J Am Soc Nephrol (2014) 1.11
Immunodeficiency and autoimmunity: lessons from systemic lupus erythematosus. Trends Mol Med (2011) 1.10
Emerging and Novel Functions of Complement Protein C1q. Front Immunol (2015) 0.99
Neutrophil extracellular traps can activate alternative complement pathways. Clin Exp Immunol (2015) 0.98
PharmGKB summary: very important pharmacogene information for N-acetyltransferase 2. Pharmacogenet Genomics (2014) 0.97
Complement in disease: a defence system turning offensive. Nat Rev Nephrol (2016) 0.97
A novel antibody against human properdin inhibits the alternative complement system and specifically detects properdin from blood samples. PLoS One (2014) 0.96
Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. J Clin Immunol (2012) 0.93
Follicular dendritic cells in health and disease. Front Immunol (2012) 0.90
The complement cascade and renal disease. Arch Immunol Ther Exp (Warsz) (2013) 0.90
The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice. Arthritis Rheum (2011) 0.89
Proteinase 3-ANCA Vasculitis versus Myeloperoxidase-ANCA Vasculitis. J Am Soc Nephrol (2015) 0.87
Current and emerging strategies for the treatment and management of systemic lupus erythematosus based on molecular signatures of acute and chronic inflammation. J Inflamm Res (2010) 0.86
To B or not to B: role of B cells in pathogenesis of arthritis in HLA transgenic mice. J Autoimmun (2011) 0.86
The critical role of complement alternative pathway regulator factor H in allergen-induced airway hyperresponsiveness and inflammation. J Immunol (2011) 0.85
The lectin pathway of complement and rheumatic heart disease. Front Pediatr (2015) 0.84
Association between copy number variation of complement component C4 and Graves' disease. J Biomed Sci (2011) 0.84
Primary biliary cirrhosis and autoimmune hepatitis: apotopes and epitopes. J Gastroenterol (2010) 0.84
Proinflammatory proteins in female and male patients with primary antiphospholipid syndrome: preliminary data. Clin Rheumatol (2016) 0.84
Analysis of immunoglobulin, complements and CRP levels in serum of captive northern pig-tailed macaques (Macaca leonina). Dongwuxue Yanjiu (2014) 0.83
Role of Complement in Autoimmune Hemolytic Anemia. Transfus Med Hemother (2015) 0.83
With complements from ANCA mice. J Am Soc Nephrol (2013) 0.83
Antineutrophilic cytoplasmic antibody-associated vasculitis with hypocomplementemia has a higher incidence of serious organ damage and a poor prognosis. Medicine (Baltimore) (2016) 0.82
Systemic Lupus Erythematosus and Deficiencies of Early Components of the Complement Classical Pathway. Front Immunol (2016) 0.82
Autoantibodies with enzymatic properties in human autoimmune diseases. J Autoimmun (2011) 0.82
Inhibition of complement alternative pathway suppresses experimental autoimmune anterior uveitis by modulating T cell responses. J Biol Chem (2011) 0.81
Novel developments in thrombotic microangiopathies: is there a common link between hemolytic uremic syndrome and thrombotic thrombocytic purpura? Pediatr Nephrol (2011) 0.81
Rosuvastatin improves impaired endothelial function, lowers high sensitivity CRP, complement and immuncomplex production in patients with systemic sclerosis--a prospective case-series study. Arthritis Res Ther (2013) 0.80
Case report: lupus nephritis with autoantibodies to complement alternative pathway proteins and C3 gene mutation. BMC Nephrol (2015) 0.80
Markers of childhood lupus nephritis indicating disease activity. Pediatr Nephrol (2010) 0.80
Complementary serum proteomic analysis of autoimmune hepatitis in mice and patients. J Transl Med (2013) 0.80
Mannose binding lectin and susceptibility to rheumatoid arthritis in Brazilian patients and their relatives. PLoS One (2014) 0.79
Polymorphisms in complement system genes and risk of non-Hodgkin lymphoma. Environ Mol Mutagen (2011) 0.79
Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study. Sci Rep (2016) 0.78
Complement in ANCA-associated vasculitis. Semin Nephrol (2013) 0.78
Complement in monoclonal antibody therapy of cancer. Immunol Res (2014) 0.78
The HLA-B*35 allele modulates ER stress, inflammation and proliferation in PBMCs from Limited Cutaneous Systemic Sclerosis patients. Arthritis Res Ther (2015) 0.77
Dysregulation of complement system and CD4+ T cell activation pathways implicated in allergic response. PLoS One (2013) 0.77
Anti-complement activity of the Ixodes scapularis salivary protein Salp20. Mol Immunol (2015) 0.77
Serum Cyr61 is associated with clinical disease activity and inflammation in patients with systemic lupus erythematosus. Medicine (Baltimore) (2015) 0.77
Update on immunoglobulin A nephropathy, Part I: Pathophysiology. World J Nephrol (2015) 0.76
1,25-Dihydroxyvitamin D3 promotes a sustained LPS-induced NF-κB-dependent expression of CD55 in human monocytic THP-1 cells. PLoS One (2012) 0.76
Celiac disease: a model disease for gene-environment interaction. Cell Mol Immunol (2011) 0.76
Enhanced dietary formulation to mitigate winter thermal stress in gilthead sea bream (Sparus aurata): a 2D-DIGE plasma proteome study. Fish Physiol Biochem (2016) 0.76
Complement C4 induces regulatory T cells differentiation through dendritic cell in systemic lupus erythematosus. Cell Biosci (2015) 0.75
The association of low complement with disease activity in systemic sclerosis: a prospective cohort study. Arthritis Res Ther (2016) 0.75
Explosion of autoimmune diseases and the mosaic of old and novel factors. Cell Mol Immunol (2011) 0.75
The Impact of T Cell Vaccination in Alleviating and Regulating Systemic Lupus Erythematosus Manifestation. J Immunol Res (2016) 0.75
C5b-9 Staining Correlates With Clinical and Tumor Stage in Gastric Adenocarcinoma. Appl Immunohistochem Mol Morphol (2016) 0.75
Comparison of molecular mechanisms of rheumatoid arthritis and osteoarthritis using gene microarrays. Mol Med Rep (2016) 0.75
Analysis of complement biomarkers in systemic sclerosis indicates a distinct pattern in scleroderma renal crisis. Arthritis Res Ther (2016) 0.75
Association of Complement C5 Gene Polymorphisms with Proliferative Diabetic Retinopathy of Type 2 Diabetes in a Chinese Han Population. PLoS One (2016) 0.75
Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N Engl J Med (2010) 11.05
Efficacy of remission-induction regimens for ANCA-associated vasculitis. N Engl J Med (2013) 5.67
Structures of complement component C3 provide insights into the function and evolution of immunity. Nature (2005) 4.01
Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. N Engl J Med (2013) 3.81
Granulomatosis with polyangiitis (Wegener's): an alternative name for Wegener's granulomatosis. Arthritis Rheum (2011) 3.60
Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases. Nat Immunol (2005) 2.82
The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility. J Immunol (2011) 2.44
Mannose binding lectin gene polymorphisms confer a major risk for severe infections after liver transplantation. Gastroenterology (2005) 2.30
Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation. Hepatology (2010) 2.25
Joint European League Against Rheumatism and European Renal Association-European Dialysis and Transplant Association (EULAR/ERA-EDTA) recommendations for the management of adult and paediatric lupus nephritis. Ann Rheum Dis (2012) 2.21
Allergy is a protective factor against age-related macular degeneration. Invest Ophthalmol Vis Sci (2014) 2.09
Pros and cons for C4d as a biomarker. Kidney Int (2012) 2.03
Neutrophil-activating potential of antineutrophil cytoplasm autoantibodies. J Leukoc Biol (2003) 1.88
Functional defect of circulating regulatory CD4+ T cells in patients with Wegener's granulomatosis in remission. Arthritis Rheum (2007) 1.86
Re-evaluation of the histopathologic classification of ANCA-associated glomerulonephritis: a study of 121 patients in a single center. Nephrol Dial Transplant (2011) 1.82
Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility. Arthritis Rheum (2002) 1.79
Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol (2006) 1.72
Bacterial infections in Wegener's granulomatosis: mechanisms potentially involved in autoimmune pathogenesis. Curr Opin Rheumatol (2011) 1.68
Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems. J Biol Chem (2003) 1.68
ANCA-associated vasculitides--advances in pathogenesis and treatment. Nat Rev Rheumatol (2010) 1.67
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q. Eur J Immunol (2003) 1.67
Mannose-binding lectin engagement with late apoptotic and necrotic cells. Eur J Immunol (2003) 1.66
Serum amyloid P component binds to late apoptotic cells and mediates their uptake by monocyte-derived macrophages. Arthritis Rheum (2003) 1.65
Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells. J Immunol (2004) 1.64
IL-10-producing macrophages preferentially clear early apoptotic cells. Blood (2006) 1.53
Direct binding of C1q to apoptotic cells and cell blebs induces complement activation. Eur J Immunol (2002) 1.52
Functional characterization of the lectin pathway of complement in human serum. Mol Immunol (2003) 1.48
Acute hepatitis B in a healthcare worker: a case report of genuine vaccination failure. J Hepatol (2008) 1.46
Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation. J Immunol (2008) 1.44
Influenza vaccination does not result in an increase in relapses in patients with ANCA-associated vasculitis. Nephrol Dial Transplant (2007) 1.44
Human anti-neutrophil cytoplasm autoantibodies to proteinase 3 (PR3-ANCA) bind to neutrophils. Kidney Int (2005) 1.42
Complement activation is involved in renal damage in human antineutrophil cytoplasmic autoantibody associated pauci-immune vasculitis. J Clin Immunol (2008) 1.42
Neutrophil membrane expression of proteinase 3 (PR3) is related to relapse in PR3-ANCA-associated vasculitis. J Am Soc Nephrol (2002) 1.41
EULAR points to consider in the development of classification and diagnostic criteria in systemic vasculitis. Ann Rheum Dis (2010) 1.38
Skewed distribution of Th17 lymphocytes in patients with Wegener's granulomatosis in remission. Arthritis Rheum (2008) 1.37
High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus. Arthritis Res Ther (2011) 1.33
Granulomatosis with polyangiitis (Wegener's): an alternative name for Wegener's granulomatosis. Ann Rheum Dis (2011) 1.33
Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation. Biochemistry (2006) 1.32
Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes. J Clin Invest (2004) 1.31
A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet (2013) 1.29
ANCA-negative pauci-immune crescentic glomerulonephritis. Nat Rev Nephrol (2009) 1.29
Current status of outcome measures in vasculitis: focus on Wegener's granulomatosis and microscopic polyangiitis. Report from OMERACT 7. J Rheumatol (2005) 1.28
Humoral responses after influenza vaccination are severely reduced in patients with rheumatoid arthritis treated with rituximab. Arthritis Rheum (2010) 1.27
The future of damage assessment in vasculitis. J Rheumatol (2007) 1.27
Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays. Proteomics (2011) 1.27
Factor B structure provides insights into activation of the central protease of the complement system. Nat Struct Mol Biol (2007) 1.27
Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood (2002) 1.26
Increase in IL-21 producing T-cells in patients with systemic lupus erythematosus. Arthritis Res Ther (2011) 1.26
Evaluation of capture ELISA for detection of antineutrophil cytoplasmic antibodies directed against proteinase 3 in Wegener's granulomatosis: first results from a multicentre study. Rheumatology (Oxford) (2003) 1.25
Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational cohort study. Arthritis Res Ther (2011) 1.24
Myeloperoxidase is critically involved in the induction of organ damage after renal ischemia reperfusion. Am J Pathol (2007) 1.24
Complement activation by (auto-) antibodies. Mol Immunol (2011) 1.22
Preclinical validation of salivary biomarkers for primary Sjögren's syndrome. Arthritis Care Res (Hoboken) (2010) 1.21
Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration. Ophthalmology (2011) 1.20
The membrane attack complex of complement induces caspase activation and apoptosis. Eur J Immunol (2002) 1.20
Maturation of dendritic cells abrogates C1q production in vivo and in vitro. Blood (2004) 1.20
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins. J Immunol (2005) 1.19
Disturbed Th1, Th2, Th17 and T(reg) balance in patients with systemic lupus erythematosus. Clin Immunol (2011) 1.19
Patients' perceptions of the effects of systemic lupus erythematosus on health, function, income, and interpersonal relationships: a comparison with Wegener's granulomatosis. Arthritis Rheum (2002) 1.18
Recognition and clearance of apoptotic cells: a role for complement and pentraxins. Trends Immunol (2003) 1.17
Connective tissue growth factor and igf-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose. Diabetes (2003) 1.16
Autoantibodies against protective molecules--C1q, C-reactive protein, serum amyloid P, mannose-binding lectin, and apolipoprotein A1: prevalence in systemic lupus erythematosus. Ann N Y Acad Sci (2007) 1.15
Antibody-mediated activation of the classical pathway of complement may compensate for mannose-binding lectin deficiency. Eur J Immunol (2004) 1.15
Human peritoneal macrophages show functional characteristics of M-CSF-driven anti-inflammatory type 2 macrophages. Eur J Immunol (2007) 1.14
Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands. Arthritis Rheum (2009) 1.14
Staphylococcus aureus and Wegener's granulomatosis. Arthritis Res (2001) 1.13
The spectrum of phenotypes caused by variants in the CFH gene. Mol Immunol (2009) 1.13
Complement activation by tubular cells is mediated by properdin binding. Am J Physiol Renal Physiol (2008) 1.12
Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage. Am J Pathol (2010) 1.12
Mini-review: A pivotal role for innate immunity in the clearance of apoptotic cells. Eur J Immunol (2004) 1.11
Health-related quality of life, employment and disability in patients with Sjogren's syndrome. Rheumatology (Oxford) (2009) 1.10
Churg-Strauss syndrome: just one disease entity? Arthritis Rheum (2005) 1.09
Urine levels of HMGB1 in Systemic Lupus Erythematosus patients with and without renal manifestations. Arthritis Res Ther (2012) 1.08
The clearance of apoptotic cells by complement. Immunobiology (2006) 1.08
Rats and mice immunised with chimeric human/mouse proteinase 3 produce autoantibodies to mouse Pr3 and rat granulocytes. Ann Rheum Dis (2007) 1.07
Urinary monocyte chemoattractant protein-1 (MCP-1) is a marker of active renal vasculitis. Nephrol Dial Transplant (2004) 1.07
Regulation of cytokine-induced HIF-1alpha expression in rheumatoid synovial fibroblasts. Ann N Y Acad Sci (2007) 1.06
Evidence that complement protein C1q interacts with C-reactive protein through its globular head region. J Immunol (2006) 1.05
Abundance of the long pentraxin PTX3 at sites of leukocytoclastic lesions in patients with small-vessel vasculitis. Arthritis Rheum (2006) 1.03
Review article: The role of CD4(+) T cells in ANCA-associated systemic vasculitis. Nephrology (Carlton) (2009) 1.03
Urinary matrix metalloproteinases reflect renal damage in anti-neutrophil cytoplasm autoantibody-associated vasculitis. Am J Physiol Renal Physiol (2007) 1.03
Low pretransplantation mannose-binding lectin levels predict superior patient and graft survival after simultaneous pancreas-kidney transplantation. J Am Soc Nephrol (2007) 1.02
Epstein-Barr virus-DNA load monitoring late after lung transplantation: a surrogate marker of the degree of immunosuppression and a safe guide to reduce immunosuppression. Transplantation (2007) 1.02
Complement production and regulation by dendritic cells: molecular switches between tolerance and immunity. Mol Immunol (2008) 1.01
Urinary CD4+ effector memory T cells reflect renal disease activity in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum (2009) 1.01
Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis. Ann Rheum Dis (2012) 1.01
Immune evasion of leptospira species by acquisition of human complement regulator C4BP. Infect Immun (2008) 1.00
Successful treatment of experimental glomerulonephritis with IdeS and EndoS, IgG-degrading streptococcal enzymes. Nephrol Dial Transplant (2010) 1.00
Molecular genetic analyses of human NKG2C (KLRC2) gene deletion. Int Immunol (2004) 1.00
Early atherosclerosis in systemic sclerosis and its relation to disease or traditional risk factors. Arthritis Res Ther (2008) 1.00
Complement in glomerular injury. Semin Immunopathol (2007) 0.99
Immune modulation of human dendritic cells by complement. Eur J Immunol (2007) 0.99
Inhibition of proinflammatory genes in anti-GBM glomerulonephritis by targeted dexamethasone-loaded AbEsel liposomes. Am J Physiol Renal Physiol (2007) 0.99
Association between mannose-binding lectin levels and graft survival in kidney transplantation. Am J Transplant (2005) 0.98
Granulomatosis with polyangiitis (Wegener's): an alternative name for Wegener's granulomatosis. J Am Soc Nephrol (2011) 0.98
Image analysis: a novel approach for the quantification of antineutrophil cytoplasmic antibody levels in patients with Wegener's granulomatosis. J Immunol Methods (2003) 0.97
Cellular immunity in Wegener's granulomatosis: characterizing T lymphocytes. Arthritis Rheum (2009) 0.97
Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus. Arthritis Res Ther (2010) 0.97
Bacterial DNA motifs trigger ANCA production in ANCA-associated vasculitis in remission. Rheumatology (Oxford) (2010) 0.97
Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody-associated vasculitis. Arthritis Rheum (2011) 0.96