Published in Shock on November 01, 2003
Epigenetic regulation of immune cell functions during post-septic immunosuppression. Epigenetics (2011) 1.38
Loss of Jak2 selectively suppresses DC-mediated innate immune response and protects mice from lethal dose of LPS-induced septic shock. PLoS One (2010) 1.07
Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages. Shock (2009) 1.00
Dendritic cell depletion exacerbates acetaminophen hepatotoxicity. Hepatology (2011) 1.00
Astragalus polysaccharides attenuate postburn sepsis via inhibiting negative immunoregulation of CD4+ CD25(high) T cells. PLoS One (2011) 0.96
Decrease of circulating dendritic cells in burn patients. Ann Burns Fire Disasters (2007) 0.92
Association between regulatory T cell activity and sepsis and outcome of severely burned patients: a prospective, observational study. Crit Care (2010) 0.90
The significance and regulatory mechanisms of innate immune cells in the development of sepsis. J Interferon Cytokine Res (2013) 0.84
Alterations of dendritic cells in sepsis: featured role in immunoparalysis. Biomed Res Int (2015) 0.82
Autophagy and ATP-induced anti-apoptosis in antigen presenting cells (APC) follows the cytokine storm in patients after major trauma. J Cell Commun Signal (2011) 0.81
Carbon monoxide down-modulates Toll-like receptor 4/MD2 expression on innate immune cells and reduces endotoxic shock susceptibility. Immunology (2015) 0.78
Adoptive transfer of fibrocytes enhances splenic T-cell numbers and survival in septic peritonitis. Shock (2013) 0.78
Major hepatectomy induces phenotypic changes in circulating dendritic cells and monocytes. J Clin Immunol (2009) 0.78
Platelet factor 4 is highly upregulated in dendritic cells after severe trauma. Mol Med (2009) 0.77
Effect of tumor necrosis factor-α induced protein 8 like-2 on immune function of dendritic cells in mice following acute insults. Oncotarget (2016) 0.76
Modulation of antigen processing by haem-oxygenase 1. Implications on inflammation and tolerance. Immunology (2016) 0.75
Genomic responses in mouse models poorly mimic human inflammatory diseases. Proc Natl Acad Sci U S A (2013) 16.74
A network-based analysis of systemic inflammation in humans. Nature (2005) 12.60
A genomic storm in critically injured humans. J Exp Med (2011) 6.67
MyD88-dependent expansion of an immature GR-1(+)CD11b(+) population induces T cell suppression and Th2 polarization in sepsis. J Exp Med (2007) 5.48
Application of genome-wide expression analysis to human health and disease. Proc Natl Acad Sci U S A (2005) 3.49
Whole blood and leukocyte RNA isolation for gene expression analyses. Physiol Genomics (2004) 3.22
Quantitative proteome analysis of human plasma following in vivo lipopolysaccharide administration using 16O/18O labeling and the accurate mass and time tag approach. Mol Cell Proteomics (2005) 2.50
Structural basis for the proinflammatory cytokine activity of high mobility group box 1. Mol Med (2003) 2.30
High dynamic range characterization of the trauma patient plasma proteome. Mol Cell Proteomics (2006) 2.25
Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care. J Trauma Acute Care Surg (2012) 2.24
Anti-TNF-alpha therapies: the next generation. Nat Rev Drug Discov (2003) 2.18
The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock. Crit Care Med (2012) 2.17
Benchmarking outcomes in the critically injured trauma patient and the effect of implementing standard operating procedures. Ann Surg (2012) 2.07
A paradoxical role for myeloid-derived suppressor cells in sepsis and trauma. Mol Med (2010) 2.06
Clinical microfluidics for neutrophil genomics and proteomics. Nat Med (2010) 2.02
B cells enhance early innate immune responses during bacterial sepsis. J Exp Med (2011) 1.99
Comparative proteome analyses of human plasma following in vivo lipopolysaccharide administration using multidimensional separations coupled with tandem mass spectrometry. Proteomics (2005) 1.94
Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients. Crit Care Med (2013) 1.94
Defective innate immunity predisposes murine neonates to poor sepsis outcome but is reversed by TLR agonists. Blood (2008) 1.94
Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis. J Immunol (2006) 1.86
Cell-specific expression and pathway analyses reveal alterations in trauma-related human T cell and monocyte pathways. Proc Natl Acad Sci U S A (2006) 1.82
Interleukin-10: a complex role in the pathogenesis of sepsis syndromes and its potential as an anti-inflammatory drug. Crit Care Med (2002) 1.78
Molecular characterization of the acute inflammatory response to infections with gram-negative versus gram-positive bacteria. Infect Immun (2003) 1.75
Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes. Hepatology (2008) 1.73
CD11c+ dendritic cells are required for survival in murine polymicrobial sepsis. J Immunol (2005) 1.71
Plasma cytokine measurements augment prognostic scores as indicators of outcome in patients with severe sepsis. Shock (2005) 1.71
Longitudinal studies of inter-alpha inhibitor proteins in severely septic patients: a potential clinical marker and mediator of severe sepsis. Crit Care Med (2007) 1.63
A better understanding of why murine models of trauma do not recapitulate the human syndrome. Crit Care Med (2014) 1.62
Human transcriptome array for high-throughput clinical studies. Proc Natl Acad Sci U S A (2011) 1.62
Continuous flow microfluidic device for rapid erythrocyte lysis. Anal Chem (2004) 1.61
CD14 receptor occupancy in severe sepsis: results of a phase I clinical trial with a recombinant chimeric CD14 monoclonal antibody (IC14). Crit Care Med (2004) 1.58
Role of Toll-like receptors in the development of sepsis. Shock (2008) 1.57
Sepsis induces early alterations in innate immunity that impact mortality to secondary infection. J Immunol (2010) 1.54
Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis. Shock (2007) 1.50
Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10. J Exp Med (2010) 1.50
A genomic score prognostic of outcome in trauma patients. Mol Med (2009) 1.48
Aberrant signaling in the TNFalpha/TNF receptor 1 pathway of the NZM2410 lupus-prone mouse. Clin Immunol (2004) 1.41
Characterization of the systemic loss of dendritic cells in murine lymph nodes during polymicrobial sepsis. J Immunol (2004) 1.36
Analysis of factorial time-course microarrays with application to a clinical study of burn injury. Proc Natl Acad Sci U S A (2010) 1.33
Treatment with GITR agonistic antibody corrects adaptive immune dysfunction in sepsis. Blood (2007) 1.29
Incidence, clinical predictors, genomics, and outcome of acute kidney injury among trauma patients. Ann Surg (2010) 1.27
Cost and Mortality Associated With Postoperative Acute Kidney Injury. Ann Surg (2015) 1.26
Large-scale multiplexed quantitative discovery proteomics enabled by the use of an (18)O-labeled "universal" reference sample. J Proteome Res (2009) 1.24
Preclinical models of shock and sepsis: what can they tell us? Shock (2005) 1.23
The origins of cachexia in acute and chronic inflammatory diseases. Nutr Clin Pract (2006) 1.23
Neutrophil mobilization from the bone marrow during polymicrobial sepsis is dependent on CXCL12 signaling. J Immunol (2011) 1.21
Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis. Circulation (2002) 1.19
Role of innate immunity in neonatal infection. Am J Perinatol (2013) 1.16
Parallels between cancer and infectious disease. N Engl J Med (2014) 1.16
Biology of interleukin-10 and its regulatory roles in sepsis syndromes. Crit Care Med (2005) 1.16
Biology of tumor necrosis factor-alpha- implications for psoriasis. Exp Dermatol (2004) 1.14
Cytokine profile after lung transplantation: correlation with allograft injury. Ann Thorac Surg (2006) 1.13
Flagellin enhances NK cell proliferation and activation directly and through dendritic cell-NK cell interactions. J Leukoc Biol (2005) 1.12
Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes. Diabetes (2011) 1.12
Critical role for CXC ligand 10/CXC receptor 3 signaling in the murine neonatal response to sepsis. Infect Immun (2011) 1.11
Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis. Anal Chem (2006) 1.11
Neutrophil elastase, MIP-2, and TLR-4 expression during human and experimental sepsis. Shock (2005) 1.09
A dynamic network of transcription in LPS-treated human subjects. BMC Syst Biol (2009) 1.07
Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma. J Trauma Acute Care Surg (2014) 1.06
Genomic and proteomic determinants of outcome in patients undergoing thoracoabdominal aortic aneurysm repair. J Immunol (2004) 1.06
Plasma proteome response to severe burn injury revealed by 18O-labeled "universal" reference-based quantitative proteomics. J Proteome Res (2010) 1.05
Interleukin-18: a novel prognostic cytokine in bacteria-induced sepsis. Crit Care Med (2006) 1.04
Inhibition of NF-kappa B augments sensitivity to 5-fluorouracil/folinic acid in colon cancer. J Surg Res (2004) 1.04
Roles of vaccinia virus genes E3L and K3L and host genes PKR and RNase L during intratracheal infection of C57BL/6 mice. J Virol (2010) 1.04
Acute kidney injury is associated with early cytokine changes after trauma. J Trauma Acute Care Surg (2013) 1.02
Differential toll-like receptor expression after ex vivo lipopolysaccharide exposure in patients with sepsis and following surgical stress. Clin Immunol (2006) 1.01
Protective immunity and defects in the neonatal and elderly immune response to sepsis. J Immunol (2014) 1.01
Cecal ligation and puncture. Curr Protoc Immunol (2010) 1.01
Functional genomics and gene expression profiling in sepsis: beyond class prediction. Clin Infect Dis (2005) 1.00
Microfluidics-based capture of human neutrophils for expression analysis in blood and bronchoalveolar lavage. Lab Invest (2011) 1.00
Human leukocyte antigen expression in sepsis: what have we learned? Crit Care Med (2005) 1.00
A critical role of CpG motifs in a murine peritonitis model by their binding to highly expressed toll-like receptor-9 on liver NKT cells. J Hepatol (2006) 1.00
Microfluidic leukocyte isolation for gene expression analysis in critically ill hospitalized patients. Clin Chem (2008) 0.99
Identification and interpretation of longitudinal gene expression changes in trauma. PLoS One (2010) 0.98
Increased lymphoid tissue apoptosis in baboons with bacteremic shock. Shock (2004) 0.97
Genome-wide monocytic mRNA expression in polytrauma patients for identification of clinical outcome. Shock (2005) 0.97
Pleiotropic IFN-dependent and -independent effects of IRF5 on the pathogenesis of experimental lupus. J Immunol (2012) 0.97
Selective activation of peripheral blood T cell subsets by endotoxin infusion in healthy human subjects corresponds to differential chemokine activation. J Immunol (2005) 0.96
Temporal patterns of gene expression in murine cutaneous burn wound healing. Physiol Genomics (2004) 0.95
Cytokines and wound healing: the role of cytokine and anticytokine therapy in the repair response. J Burn Care Rehabil (2004) 0.94
Is there value in plasma cytokine measurements in patients with severe trauma and sepsis? Methods (2013) 0.93
Cancer-induced expansion and activation of CD11b+ Gr-1+ cells predispose mice to adenoviral-triggered anaphylactoid-type reactions. Mol Ther (2009) 0.93
Role of endogenous interleukin-10 in local and distant organ injury after visceral ischemia-reperfusion. Shock (2003) 0.91
Pro- and antiinflammatory cytokine production after radiofrequency ablation of unresectable hepatic tumors. J Am Coll Surg (2002) 0.91
Differences in outcome between obese and nonobese patients following severe blunt trauma are not consistent with an early inflammatory genomic response. Crit Care Med (2010) 0.91
Maturation of murine bone marrow-derived dendritic cells with poly(I:C) produces altered TLR-9 expression and response to CpG DNA. Immunol Lett (2006) 0.89
Traditional resuscitative practices fail to resolve metabolic acidosis in morbidly obese patients after severe blunt trauma. J Trauma (2010) 0.89
Increased survival in sepsis by in vivo adenovirus-induced expression of IL-10 in dendritic cells. J Immunol (2002) 0.89
Stored packed red blood cell transfusion up-regulates inflammatory gene expression in circulating leukocytes. Ann Surg (2007) 0.89
Obese patients show a depressed cytokine profile following severe blunt injury. Shock (2012) 0.89
Aged mice are unable to mount an effective myeloid response to sepsis. J Immunol (2013) 0.89
Determination of burn patient outcome by large-scale quantitative discovery proteomics. Crit Care Med (2013) 0.88
Monocyte chemoattractant protein-1/CCR2 axis promotes vein graft neointimal hyperplasia through its signaling in graft-extrinsic cell populations. Arterioscler Thromb Vasc Biol (2012) 0.88
Interleukin-6 and STAT3 protect the liver from hepatic ischemia and reperfusion injury during ischemic preconditioning. Surgery (2006) 0.88
HMGB1 as a therapeutic target for sepsis: it's all in the timing! Expert Opin Ther Targets (2014) 0.88
Delayed neutralization of interferon-gamma prevents lethality in primate Gram-negative bacteremic shock. Crit Care Med (2005) 0.87
Differential maturation of murine bone-marrow derived dendritic cells with lipopolysaccharide and tumor necrosis factor-alpha. J Endotoxin Res (2005) 0.86
Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome. Crit Care Med (2016) 0.86
Maintenance of anti-Sm/RNP autoantibody production by plasma cells residing in ectopic lymphoid tissue and bone marrow memory B cells. J Immunol (2013) 0.85