Published in Mol Cell Biol on December 01, 2003
p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription. J Biol Chem (2010) 3.84
Role of nrf2 in oxidative stress and toxicity. Annu Rev Pharmacol Toxicol (2013) 3.73
Heme oxygenase-1 regulates cardiac mitochondrial biogenesis via Nrf2-mediated transcriptional control of nuclear respiratory factor-1. Circ Res (2008) 3.12
When NRF2 talks, who's listening? Antioxid Redox Signal (2010) 2.32
Retracted Expression of concern: Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. Am J Respir Crit Care Med (2009) 2.28
Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells. Mol Cell (2010) 2.24
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Regulation of proteasome activity in health and disease. Biochim Biophys Acta (2013) 1.52
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Regulation of notch1 signaling by nrf2: implications for tissue regeneration. Sci Signal (2010) 1.50
Chemoprotection by sulforaphane: keep one eye beyond Keap1. Cancer Lett (2006) 1.50
Oxidative stress-mediated regulation of proteasome complexes. Mol Cell Proteomics (2011) 1.50
Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress. J Biol Chem (2012) 1.46
Accelerated ovarian failure induced by 4-vinyl cyclohexene diepoxide in Nrf2 null mice. Mol Cell Biol (2006) 1.45
Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications. Apoptosis (2010) 1.31
Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis. Hum Mol Genet (2008) 1.24
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NRF2, cancer and calorie restriction. Oncogene (2010) 1.17
Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. J Biol Chem (2010) 1.16
Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages. Toxicol Appl Pharmacol (2009) 1.15
Treatment-induced oxidative stress and cellular antioxidant capacity determine response to bortezomib in mantle cell lymphoma. Clin Cancer Res (2011) 1.14
Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis. Free Radic Biol Med (2011) 1.13
The NRF2-heme oxygenase-1 system modulates cyclosporin A-induced epithelial-mesenchymal transition and renal fibrosis. Free Radic Biol Med (2010) 1.12
HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress. Free Radic Biol Med (2011) 1.11
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SPBP is a sulforaphane induced transcriptional coactivator of NRF2 regulating expression of the autophagy receptor p62/SQSTM1. PLoS One (2014) 0.80
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Piper betle induces phase I & II genes through Nrf2/ARE signaling pathway in mouse embryonic fibroblasts derived from wild type and Nrf2 knockout cells. BMC Complement Altern Med (2014) 0.79
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FABP4/aP2 regulates macrophage redox signaling and inflammasome activation via control of UCP2. Mol Cell Biol (2016) 0.76
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Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases. Redox Biol (2017) 0.76
Nuclear factor erythroid-2 related factor 2 (Nrf2)-mediated protein quality control in cardiomyocytes. Front Biosci (Landmark Ed) (2016) 0.76
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Chronic Heat Stress Induces Immune Response, Oxidative Stress Response, and Apoptosis of Finishing Pig Liver: A Proteomic Approach. Int J Mol Sci (2016) 0.75
Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis. Sci Rep (2017) 0.75
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Thioridazine enhances sensitivity to carboplatin in human head and neck cancer cells through downregulation of c-FLIP and Mcl-1 expression. Cell Death Dis (2017) 0.75
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Dysregulated Nox4 ubiquitination contributes to redox imbalance and age-related severity of acute lung injury. Am J Physiol Lung Cell Mol Physiol (2017) 0.75
Agrimonolide and Desmethylagrimonolide Induced HO-1 Expression in HepG2 Cells through Nrf2-Transduction and p38 Inactivation. Front Pharmacol (2017) 0.75
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