Published in Nat Struct Mol Biol on December 29, 2003
Single-molecule force spectroscopy: optical tweezers, magnetic tweezers and atomic force microscopy. Nat Methods (2008) 6.75
Exploring the energy landscape of GFP by single-molecule mechanical experiments. Proc Natl Acad Sci U S A (2004) 2.65
Anisotropic deformation response of single protein molecules. Proc Natl Acad Sci U S A (2006) 2.28
Structure of three tandem filamin domains reveals auto-inhibition of ligand binding. EMBO J (2007) 1.85
Revealing the bifurcation in the unfolding pathways of GFP by using single-molecule experiments and simulations. Proc Natl Acad Sci U S A (2007) 1.74
Cytoskeletal polymer networks: the molecular structure of cross-linkers determines macroscopic properties. Proc Natl Acad Sci U S A (2006) 1.73
Protein structure by mechanical triangulation. Proc Natl Acad Sci U S A (2006) 1.65
Mechanically unfolding the small, topologically simple protein L. Biophys J (2005) 1.57
Cytoskeletal bundle mechanics. Biophys J (2007) 1.55
Five challenges to bringing single-molecule force spectroscopy into living cells. Nat Methods (2011) 1.45
Conformational changes and signaling in cell and matrix physics. Curr Biol (2009) 1.33
Direct observation of active protein folding using lock-in force spectroscopy. Biophys J (2007) 1.32
Atomic force microscopy reveals parallel mechanical unfolding pathways of T4 lysozyme: evidence for a kinetic partitioning mechanism. Proc Natl Acad Sci U S A (2008) 1.30
The folding pathway of a fast-folding immunoglobulin domain revealed by single-molecule mechanical experiments. EMBO Rep (2005) 1.21
Stepwise unfolding of ankyrin repeats in a single protein revealed by atomic force microscopy. Biophys J (2005) 1.20
Dynamic force sensing of filamin revealed in single-molecule experiments. Proc Natl Acad Sci U S A (2012) 1.17
Influence of substrate binding on the mechanical stability of mouse dihydrofolate reductase. Biophys J (2005) 1.11
Selection of optimal variants of Gō-like models of proteins through studies of stretching. Biophys J (2008) 1.10
The counterbend phenomenon in dynein-disabled rat sperm flagella and what it reveals about the interdoublet elasticity. Biophys J (2005) 1.00
Mechanical properties of bovine rhodopsin and bacteriorhodopsin: possible roles in folding and function. Langmuir (2008) 0.99
Phosphorylation facilitates the integrin binding of filamin under force. Biophys J (2009) 0.99
Molecular mechanics of filamin's rod domain. Biophys J (2007) 0.95
Fast and forceful refolding of stretched alpha-helical solenoid proteins. Biophys J (2010) 0.95
Complex unfolding kinetics of single-domain proteins in the presence of force. Biophys J (2010) 0.94
Single molecule mechanics of the kinesin neck. Proc Natl Acad Sci U S A (2009) 0.94
Analyzing forced unfolding of protein tandems by ordered variates, 1: Independent unfolding times. Biophys J (2007) 0.91
Fast-folding alpha-helices as reversible strain absorbers in the muscle protein myomesin. Proc Natl Acad Sci U S A (2011) 0.89
Flexible light-chain and helical structure of F-actin explain the movement and step size of myosin-VI. Biophys J (2006) 0.88
Order statistics theory of unfolding of multimeric proteins. Biophys J (2010) 0.88
Secondary structure, mechanical stability, and location of transition state of proteins. Biophys J (2007) 0.88
N-terminal strands of filamin Ig domains act as a conformational switch under biological forces. Proteins (2010) 0.87
Dynamic role of cross-linking proteins in actin rheology. Biophys J (2011) 0.86
The effect of temperature on mechanical resistance of the native and intermediate states of I27. Biophys J (2008) 0.86
Retracted Stretching to understand proteins - a survey of the protein data bank. Biophys J (2007) 0.86
Characterizing folding, structure, molecular interactions and ligand gated activation of single sodium/proton antiporters. Naunyn Schmiedebergs Arch Pharmacol (2006) 0.84
Mechanobiology of platelets: techniques to study the role of fluid flow and platelet retraction forces at the micro- and nano-scale. Int J Mol Sci (2011) 0.83
Single-molecule force spectroscopy distinguishes target binding modes of calmodulin. Proc Natl Acad Sci U S A (2009) 0.83
The c2 domains of human synaptotagmin 1 have distinct mechanical properties. Biophys J (2009) 0.82
Tracking unfolding and refolding reactions of single proteins using atomic force microscopy methods. Methods (2013) 0.80
Detailed analysis of putative genes encoding small proteins in legume genomes. Front Plant Sci (2013) 0.79
Single-molecule experiments reveal the flexibility of a Per-ARNT-Sim domain and the kinetic partitioning in the unfolding pathway under force. Biophys J (2012) 0.79
Nucleotides regulate the mechanical hierarchy between subdomains of the nucleotide binding domain of the Hsp70 chaperone DnaK. Proc Natl Acad Sci U S A (2015) 0.78
Protein unfolding under force: crack propagation in a network. Biophys J (2011) 0.77
Connecting thermal and mechanical protein (un)folding landscapes. Biophys J (2014) 0.77
Cross-species mechanical fingerprinting of cardiac myosin binding protein-C. Biophys J (2013) 0.77
Mechanically unfolding protein L using a laser-feedback-controlled cantilever. Biophys J (2011) 0.76
Mechanics of proteins with a focus on atomic force microscopy. J Nanobiotechnology (2013) 0.76
Filamin structure, function and mechanics: are altered filamin-mediated force responses associated with human disease? Biophys Rev (2011) 0.75
Stochastic emergence of multiple intermediates detected by single-molecule quasi-static mechanical unfolding of protein. Biophysics (Nagoya-shi) (2009) 0.75
Mechanical unfolding studies of protein molecules. Biophysics (Nagoya-shi) (2012) 0.75
The mechanochemistry of copper reports on the directionality of unfolding in model cupredoxin proteins. Nat Commun (2015) 0.75
Mathematical modeling of Myosin induced bistability of Lamellipodial fragments. J Math Biol (2016) 0.75
As Simple As Possible, but Not Simpler: Exploring the Fidelity of Coarse-Grained Protein Models for Simulated Force Spectroscopy. PLoS Comput Biol (2016) 0.75
Simulation of lamellipodial fragments. J Math Biol (2011) 0.75
Energetics and dynamics of global integrals modeling interaction between stiff filaments. J Math Biol (2008) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope. J Cell Sci (2005) 3.33
Sequence and analysis of chromosome 2 of Dictyostelium discoideum. Nature (2002) 3.01
NUANCE, a giant protein connecting the nucleus and actin cytoskeleton. J Cell Sci (2002) 2.83
Filamins: promiscuous organizers of the cytoskeleton. Trends Biochem Sci (2006) 2.79
Exploring the energy landscape of GFP by single-molecule mechanical experiments. Proc Natl Acad Sci U S A (2004) 2.65
The Diaphanous-related formin dDia2 is required for the formation and maintenance of filopodia. Nat Cell Biol (2005) 2.47
The myosin coiled-coil is a truly elastic protein structure. Nat Mater (2002) 2.38
The complex folding network of single calmodulin molecules. Science (2011) 2.37
A rapid and efficient method to generate multiple gene disruptions in Dictyostelium discoideum using a single selectable marker and the Cre-loxP system. Nucleic Acids Res (2004) 2.31
Can tyrosine kinase inhibitors be discontinued in patients with metastatic renal cell carcinoma and a complete response to treatment? A multicentre, retrospective analysis. Eur Urol (2008) 2.29
Single-molecule folding. Curr Opin Struct Biol (2003) 2.28
Anisotropic deformation response of single protein molecules. Proc Natl Acad Sci U S A (2006) 2.28
Enaptin, a giant actin-binding protein, is an element of the nuclear membrane and the actin cytoskeleton. Exp Cell Res (2004) 2.27
Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope. Mol Biol Cell (2005) 2.15
Ligand-dependent equilibrium fluctuations of single calmodulin molecules. Science (2009) 2.05
Force-dependent stepping kinetics of myosin-V. Biophys J (2005) 1.88
Nesprin-2 Giant (NUANCE) maintains nuclear envelope architecture and composition in skin. J Cell Sci (2008) 1.86
Full distance-resolved folding energy landscape of one single protein molecule. Proc Natl Acad Sci U S A (2010) 1.85
Myosin-V is a mechanical ratchet. Proc Natl Acad Sci U S A (2006) 1.83
Revealing the bifurcation in the unfolding pathways of GFP by using single-molecule experiments and simulations. Proc Natl Acad Sci U S A (2007) 1.74
The bundling activity of vasodilator-stimulated phosphoprotein is required for filopodium formation. Proc Natl Acad Sci U S A (2006) 1.72
Pathological consequences of VCP mutations on human striated muscle. Brain (2006) 1.68
Protein structure by mechanical triangulation. Proc Natl Acad Sci U S A (2006) 1.65
Temperature softening of a protein in single-molecule experiments. J Mol Biol (2005) 1.59
Single-molecule unfolding force distributions reveal a funnel-shaped energy landscape. Biophys J (2005) 1.58
Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton. J Cell Sci (2009) 1.58
Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication. Genome Res (2011) 1.53
Comparison of non-gated vs. electrocardiogram-gated 64-detector-row computed tomography for integrated electroanatomic mapping in patients undergoing pulmonary vein isolation. Europace (2010) 1.50
The titin-telethonin complex is a directed, superstable molecular bond in the muscle Z-disk. Proc Natl Acad Sci U S A (2009) 1.40
Direct observation of active protein folding using lock-in force spectroscopy. Biophys J (2007) 1.32
The cyclase-associated protein CAP as regulator of cell polarity and cAMP signaling in Dictyostelium. Mol Biol Cell (2003) 1.30
Practical aspects of the 2D 15N-[1h]-NOE experiment. J Biomol NMR (2002) 1.29
Oligomerization, F-actin interaction, and membrane association of the ubiquitous mammalian coronin 3 are mediated by its carboxyl terminus. J Biol Chem (2002) 1.29
Reticulon 4B (Nogo-B) is necessary for macrophage infiltration and tissue repair. Proc Natl Acad Sci U S A (2009) 1.27
The LINC-less granulocyte nucleus. Eur J Cell Biol (2008) 1.26
Dictyostelium Sun-1 connects the centrosome to chromatin and ensures genome stability. Traffic (2008) 1.26
Dictyostelium transcriptional host cell response upon infection with Legionella. Cell Microbiol (2006) 1.22
The folding pathway of a fast-folding immunoglobulin domain revealed by single-molecule mechanical experiments. EMBO Rep (2005) 1.21
Phospholipids regulate localization and activity of mDia1 formin. Eur J Cell Biol (2010) 1.20
Nesprin-2 giant safeguards nuclear envelope architecture in LMNA S143F progeria cells. Hum Mol Genet (2007) 1.20
Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope. Cell Mol Life Sci (2010) 1.20
High-resolution dissection of phagosome maturation reveals distinct membrane trafficking phases. Mol Biol Cell (2002) 1.18
Dynamic force sensing of filamin revealed in single-molecule experiments. Proc Natl Acad Sci U S A (2012) 1.17
Various bacterial pathogens and symbionts infect the amoeba Dictyostelium discoideum. Int J Med Microbiol (2002) 1.15
Blue light perception in plants. Detection and characterization of a light-induced neutral flavin radical in a C450A mutant of phototropin. J Biol Chem (2003) 1.14
Collapsin response mediator protein-4 regulates F-actin bundling. Exp Cell Res (2005) 1.14
Sun1 forms immobile macromolecular assemblies at the nuclear envelope. Biochim Biophys Acta (2008) 1.12
Molecular structure of the rod domain of dictyostelium filamin. J Mol Biol (2004) 1.12
From mechanical folding trajectories to intrinsic energy landscapes of biopolymers. Proc Natl Acad Sci U S A (2013) 1.10
Mechanical unfoldons as building blocks of maltose-binding protein. J Mol Biol (2008) 1.08
Highly stretched single polymers: atomic-force-microscope experiments versus ab-initio theory. Phys Rev Lett (2005) 1.08
Tightening the knot in phytochrome by single-molecule atomic force microscopy. Biophys J (2009) 1.06
Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila. Cell Microbiol (2010) 1.06
Single-molecule dynamics of mechanical coiled-coil unzipping. Langmuir (2007) 1.04
Nesprin-2 interacts with {alpha}-catenin and regulates Wnt signaling at the nuclear envelope. J Biol Chem (2010) 1.04
eNOS-derived nitric oxide regulates endothelial barrier function through VE-cadherin and Rho GTPases. J Cell Sci (2013) 1.04
Elastic bond network model for protein unfolding mechanics. Phys Rev Lett (2008) 1.03
Force as a single molecule probe of multidimensional protein energy landscapes. Curr Opin Struct Biol (2012) 1.03
Accelerated clearance of Plasmodium-infected erythrocytes in sickle cell trait and annexin-A7 deficiency. Cell Physiol Biochem (2009) 1.02
Torque generation of kinesin motors is governed by the stability of the neck domain. Mol Cell (2012) 1.01
Myosin V stepping mechanism. Proc Natl Acad Sci U S A (2007) 1.01
Regulation of a heterodimeric kinesin-2 through an unprocessive motor domain that is turned processive by its partner. Proc Natl Acad Sci U S A (2010) 1.01
Hsp27-2D-gel electrophoresis is a diagnostic tool to differentiate primary desminopathies from myofibrillar myopathies. FEBS Lett (2005) 1.00
The Dictyostelium genome encodes numerous RasGEFs with multiple biological roles. Genome Biol (2005) 1.00
Structures of actin-bound Wiskott-Aldrich syndrome protein homology 2 (WH2) domains of Spire and the implication for filament nucleation. Proc Natl Acad Sci U S A (2010) 1.00
gamma-Parvin is dispensable for hematopoiesis, leukocyte trafficking, and T-cell-dependent antibody response. Mol Cell Biol (2006) 1.00
Single molecule unzipping of coiled coils: sequence resolved stability profiles. Phys Rev Lett (2006) 1.00
Coronin 3 involvement in F-actin-dependent processes at the cell cortex. Exp Cell Res (2006) 1.00
Functions of LIM proteins in cell polarity and chemotactic motility. EMBO J (2002) 0.99
Nitric oxide synthase (NOS)-interacting protein interacts with neuronal NOS and regulates its distribution and activity. J Neurosci (2004) 0.99
Yersinia protein kinase YopO is activated by a novel G-actin binding process. J Biol Chem (2006) 0.99
Linking Ras to myosin function: RasGEF Q, a Dictyostelium exchange factor for RasB, affects myosin II functions. J Cell Biol (2008) 0.98
The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus (2012) 0.98
Calcium-dependent folding of single calmodulin molecules. Proc Natl Acad Sci U S A (2012) 0.98
LINC complex alterations in DMD and EDMD/CMT fibroblasts. Eur J Cell Biol (2012) 0.96
Superhelical architecture of the myosin filament-linking protein myomesin with unusual elastic properties. PLoS Biol (2012) 0.96
Hidden Markov analysis of trajectories in single-molecule experiments and the effects of missed events. Chemphyschem (2012) 0.96
Unusual combinatorial involvement of poly-A/T tracts in organizing genes and chromatin in Dictyostelium. Genome Res (2012) 0.96
Auto- and cross-power spectral analysis of dual trap optical tweezer experiments using Bayesian inference. Rev Sci Instrum (2012) 0.96
Cysteine engineering of polyproteins for single-molecule force spectroscopy. Nat Protoc (2006) 0.96
Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection. Traffic (2006) 0.96
Ligand binding mechanics of maltose binding protein. J Mol Biol (2009) 0.95
Enhanced heterogeneity of myocardial conduction and severe cardiac electrical instability in annexin A7-deficient mice. Cardiovasc Res (2007) 0.95
Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex. Proc Natl Acad Sci U S A (2010) 0.95
Induction of autoimmune diabetes through insulin (but not GAD65) DNA vaccination in nonobese diabetic and in RIP-B7.1 mice. Diabetes (2002) 0.95
CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet (2013) 0.95
Rigid DNA beams for high-resolution single-molecule mechanics. Angew Chem Int Ed Engl (2013) 0.94
Complex unfolding kinetics of single-domain proteins in the presence of force. Biophys J (2010) 0.94
Reduction of claustrophobia during magnetic resonance imaging: methods and design of the "CLAUSTRO" randomized controlled trial. BMC Med Imaging (2011) 0.94
Regulation of the actin cytoskeleton by an interaction of IQGAP related protein GAPA with filamin and cortexillin I. PLoS One (2010) 0.94
Nesprin interchain associations control nuclear size. Cell Mol Life Sci (2012) 0.94